• Title/Summary/Keyword: E-ICP

Search Result 181, Processing Time 0.033 seconds

The separation of arsenic metabolites in urine by high performance liquid chromatography-inductively coupled plasma-mass spectrometry

  • Chung, Jin-Yong;Lim, Hyoun-Ju;Kim, Young-Jin;Song, Ki-Hoon;Kim, Byoung-Gwon;Hong, Young-Seoub
    • Environmental Analysis Health and Toxicology
    • /
    • v.29
    • /
    • pp.18.1-18.9
    • /
    • 2014
  • Objectives The purpose of this study was to determine a separation method for each arsenic metabolite in urine by using a high performance liquid chromatography (HPLC)-inductively coupled plasma-mass spectrometer (ICP-MS). Methods Separation of the arsenic metabolites was conducted in urine by using a polymeric anion-exchange (Hamilton PRP X-100, $4.6mm{\times}150mm$, $5{\mu}m$) column on Agilent Technologies 1260 Infinity LC system coupled to Agilent Technologies 7700 series ICP/MS equipment using argon as the plasma gas. Results All five important arsenic metabolites in urine were separated within 16 minutes in the order of arsenobetaine, arsenite, dimethylarsinate, monomethylarsonate and arsenate with detection limits ranging from 0.15 to $0.27{\mu}g/L$ ($40{\mu}L$ injection). We used G-EQUAS No. 52, the German external quality assessment scheme and standard reference material 2669, National Institute of Standard and Technology, to validate our analyses. Conclusions The method for separation of arsenic metabolites in urine was established by using HPLC-ICP-MS. This method contributes to the evaluation of arsenic exposure, health effect assessment and other bio-monitoring studies for arsenic exposure in South Korea.

Large Area Plasma Characteristics using Internal Linear ICP (Inductively Coupled Plasma) Source for the FPD processing

  • Kim, Kyong-Nam;Lim, Jong-Hyeuk;Yeom, Geun-Young
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2006.08a
    • /
    • pp.544-547
    • /
    • 2006
  • In this study, the characteristics of large area internal linear ICP sources of $1,020mm{\times}920mm$ (substrate area is $880mm{\times}660mm$) were investigated using a multiple linear antennas with U-type parallel connection. Using the multiple linear antennas with U-type parallel connection, a high plasma density of $2{\times}10^{11}/cm^3$ and a high power transfer efficiency of about 88% could be obtained at 5kW of RF power and with 20mTorr Ar. A low plasma potential of less than 26V and a low electron temperature of $2.6{\sim}3.2eV$ could be also obtained. The measured plasma uniformity on the substrate size of 4th generation $(880mm{\times}660mm)$ was about 4%, therefore, it is believed that the multiple linear antennas with U-type parallel connection can be successfully applicable to the large area flat panel display processing.

  • PDF

Characteristics and Analysis of Natural Pine-Needles Extract (천연 솔잎추출물의 특성 및 분석)

  • Sung, Ki-Chun
    • Journal of the Korean Applied Science and Technology
    • /
    • v.21 no.4
    • /
    • pp.320-326
    • /
    • 2004
  • We have extracted the natural pine-needles to use ethanol in solvent, and could obtain the refined oil component from pine-needles extract. We have tested the antimicrobial effect from microbe experiment and analyzed with ICP/OES, GC/MS. we could obtain the next conclusion from the result of this experiment. In the first result of this experiment we could know that in case of increasing concentration of pine-needles, the number of microbe decreased more and more. Also we could know that the refined oil component of pine-needles appeared the sterilization effect of S-aureus and E-coli after 96hrs and 120hrs. So we could know that the refined oil component of appeared effect to microbe. In the second result of this experiment we could know that inorganic materials of Ca, Mg, V, Mn etcs from pine-needles detected to ICP/OES analysis and the aromatic compounds from refined oil component of pine-needles was certificated to GC/MS analysis.

The Matrix Effect of Biological Concomitant Element on the Signal Intensity of Ge, As, And Se in Inductively Coupled Plasma/Mass Spectrometry

  • Park, Kyung-Su;Kim, Sun-Tae;Kim, Young-Man;Kim, Yun-je;Lee, Won
    • Bulletin of the Korean Chemical Society
    • /
    • v.23 no.10
    • /
    • pp.1389-1393
    • /
    • 2002
  • The non-spectroscopic interference effects that occurred in inductively coupled plasma/mass spectrometry were studied for Ge, As and Se in human urine and serum. Many biological samples contain Na, K, Cl and organic compounds, which may cause the enhancement and depression on the analyte signal. The effect of 1% concomitant elements such as N, Cl, S, P, C, Na, and K on a 100 ㎍/L germanium, arsenic and selenium signal has been investigated by ICP/MS. The interference effects were not in the same direction. It appeared that concomitant elements such as Cl, S, and C induce an enhancement effect, whereas N and P did not show any significant effect. And, Na and K caused a depression. We have found a link between the abundance of analytes and the ionization potential of concomitant elements (eV), except carbon and nitrogen.

Numerical Modeling of Plasma Characteristics of ICP System with a Pulsed dc Bias (수치모델을 이용한 pulsed dc bias ICP장치의 플라즈마 특성 해석)

  • Joo, Jung-Hoon
    • Journal of the Korean institute of surface engineering
    • /
    • v.43 no.3
    • /
    • pp.154-158
    • /
    • 2010
  • Numerical analysis is done to investigate the effects of pulse bias on the plasma processing characteristics like ion doping and ion nitriding by using fluid dynamic code with a 2D axi-symmetric model. For 10 mTorr of Ar plasma, -1 kV of pulse bias was simulated. Maximum sheath thickness was around 20 mm based on the electric potential profile. The peak electron temperature was about 20 eV, but did not affect the averaged plasma characteristics of the whole chamber. Maximum ion current density incident on the substrate was 200 $A/m^2$ at the center, but was decreased down to 1/10th at radius 100 mm, giving poor radial uniformity.

Effect of the Brain Death on Hemodynamic Changes and Myocardial Damages in Canine Brain Death Model -Electrocard iographic and Hemodynamic Changes in the Brain Death Model Induced by Gradual Increase of Intracranial Pressure- (잡견을 이용한 실험적 뇌사모델에서 뇌사가 혈역학적 변화와 심근손상에 미치는 영향 -제2보 : 뇌압을 점진적으로 증가시켜 유발한 뇌사모델의 심전도 및 혈역학적 변화-)

  • 조명찬;이동운
    • Journal of Chest Surgery
    • /
    • v.29 no.1
    • /
    • pp.1-6
    • /
    • 1996
  • We developed an experimental model of brain death using dogs. Brain death was induced by increasing the intracranial pressure (ICP) gradually by continuous Infusion of saline through an epidural Foley catheter in 5 mongrel dogs (weight, 18~22kg). Hemodynamic and electrocardiographic changes were evaluated continuously during the process of brain death and obtained the following results. 1. The average volume and time required to induce brain death was 4.8$\pm$1.0ml and 143.0$\pm$30.9minutes respectively. 2. There was a steady rise of the ICP after starting the constant infusion of saline, and ICP rised continuously until the brain death (122.0$\pm$62.5mmHg). After reaching to the maximal value (125.0$\pm$47.7mmHg) at 30 minutes after brain death, the ICP dropped and remained approximately constant at the slightly higher level than the mean arterial pressure (MAP). 3. MAP showed no change until the establishment of brain death and it declined gradually. The peak heart rate reached to 172.6$\pm$35.3/min at 30 minutes after the brain death. 4. Even though the body temperature and all hemodynamic variables, such as cardiac output, mean pulmonary arterial pressure, left ventricular (LV) end-diastolic pressure and LV maximum + dp/dt, were slightly greater than those of basal state, at the point of brain death, there was no statistically significant change during t e process of brain death. 5. There was no remarkable arrhythmias during the experiment except ventricular premature beats which was observed transiently in one dog at the time of brain death. Hemodynamic changes in the brain death model induced by gradual ICP increment were inconspicuous, and arrhythmias were rarely seen. Hyperdynamic state, which was observed at the point of brain death in another brain death model caused by abrupt ICP increase, was not observed.

  • PDF

The Effects of Herbal Formula (KH-204) on the Penile Erection and Corpus Cavernosum of Spontaneous Hypertensive Male Rats (본태성 고혈압 수컷 흰쥐에서 복합생약제제 (KH-204)가 음경발기 및 음경해면체 조직에 미치는 효과)

  • Sohn, Dong-Wan;Yoon, Byung-Il;Kim, Sung-Dae;Lee, Eun-Jeong;Kim, Hee-Seok;Hwang, Sung-Wan;Hwang, Sung-Yeoun;Kim, Du-Bae;Kim, Hyun-Woo;Cho, Yong-Hyun;Kim, Sae-Woong
    • Korean Journal of Pharmacognosy
    • /
    • v.38 no.3 s.150
    • /
    • pp.239-244
    • /
    • 2007
  • The herbal formulation (KH-204) mainly consisted of the fruits of Lycium chinense, Cornus officinalis, Rubus coreanus, Cuscuta chinensis and Schizandra chinensis. We investigated the effects of this herbal formulation on the penile erection and corpus cavernosum of spontaneous hypertensive male Rats (SHR). We used male SHR aged 16 weeks as a model of hypertension. The treatment groups received once a day oral doses KH-204 100 and 300 mg/kg per day for 4 weeks. Distilled water was administered in the control group. To investigate the penile erection, intracavernosal pressure (ICP) and mean arterial pressure (MAP) were recorded in all groups. We analyzed the distribution of NOS by immunohistochemical staining and the expression of nNOS, eNOS concentration in the isolated corpus cavernosum by western blotting. In the control group, ICP/MAP ratio was $14.9{\pm}1.4%$ after pelvic nerve stimulation. ICP/MAP ratio was markedly increased in the treatment group with KH-204 100, 300 mg/kg, compared with control group. Immunohistochemical staining for NOS showed that eNOS and nNOS was stained as brown color. Compared with the control group, NOS activities of KH-204 100, 300 mg/kg were increased significantly. Also the penile expression levels of nNOS, eNOS in KH-204 100, 300 mg/kg treatment group were more increased significantly than control group by western blotting. This study showed that KH-204 enhances the penile erection and the level of eNOS and nNOS expression of penile corpus cavernosum of male SHR.

Method development for quantitative analysis of naturally occurring radioactive nuclides in building materials (실내 건축자재 중 천연방사성핵종의 정량분석법 연구)

  • Lim, Jong-Myoung;Lee, Hoon;Kim, Chang-Jong;Jang, Mee;Park, Ji-Young;Chung, Kun Ho
    • Analytical Science and Technology
    • /
    • v.30 no.5
    • /
    • pp.252-261
    • /
    • 2017
  • Naturally occurring radioactive materials (NORMs) increase radiation exposure to the public as these materials are concentrated through artificial manufacturing processes by human activities. This study focuses on the development of a method for the quantitative analysis of $^{232}Th$, $^{235}U$, and $^{238}U$ in building materials. The accuracy and precision of inductively coupled plasma mass spectrometry (ICP-MS) for determination of digestion processes was evaluated for certified reference materials (CRMs) digested using various mixed acid (e.g., aqua regia, hydrofluoric acid, and perchloric acid) digestions and a $LiBO_2$ fusion method. The method validation results reveal that a $LiBO_2$ fusion and $Fe(OH)_3$ co-precipitation should be applied as the optimal sample digestion process for the quantitative analysis of radionuclides in building materials. The radioactivity of $^{232}Th$, $^{235}U$, and $^{238}U$ in a total of 51 building material (e.g., board, brick, cement, paint, tile, and wall paper) samples was quantitatively analyzed using an established process. Finally, the values of $^{238}U$ and $^{232}Th$ radioactivity were comprehensively compared with those from the indirect method using ${\gamma}$-spectrometry.

Removal of Cu(II) ions by Alginate/Carbon Nanotube/Maghemite Composite Magnetic Beads

  • Jeon, Son-Yeo;Yun, Ju-Mi;Lee, Young-Seak;Kim, Hyung-Il
    • Carbon letters
    • /
    • v.11 no.2
    • /
    • pp.117-121
    • /
    • 2010
  • The composites of alginate, carbon nanotube, and iron(III) oxide were prepared for the removal of heavy metal in aqueous pollutant. Both alginate and carbon nanotube were used as an adsorbent material and iron oxide was introduced for the easy recovery after removal of heavy metal to eliminate the secondary pollution. The morphology of composites was investigated by FE-SEM showing the carbon nanotubes coated with alginate and the iron oxide dispersed in the alginate matrix. The ferromagnetic properties of composites were shown by including iron(III) oxide additive. The copper ion removal was investigated with ICP AES. The copper ion removal efficiency increased greatly over 60% by using alginate-carbon nanotube composites.

Study on Retardation Effect of a Heavy Metal in Sandy Soils

  • Kim, Dong-Ju;Sung, Baek-Doo
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
    • /
    • 1998.06a
    • /
    • pp.43-49
    • /
    • 1998
  • Retardation effect of heavy metals in soils caused by adsorption onto the surfaces of solids particles is well known phenomena. The adsorption of metal ions has been recognized more strong in clay mineral and organic matter contents rather than sands and gravels. In this study, we investigated the retardation effect in two sandy soils by conducting batch and column tests. The column tests were conducted to obtain the relationship between concentration and time known as breakthrough curve (BTC). We applied pulse type injection of ZnCl$_2$solution on the inlet boundary and monitored the effluent concentration at the exit boundary under steady state condition using EC-meter and ICP-AES. Batch test consisted of an equilibrium procedure for fine fractions collected from two sandy soils for various initial ZnCl$_2$concentrations, and analysis of Zn ions in equilibrated solution using ICP-AES. The results of column test showed that i) the peak concentration of Zn analyzed by ICP was far less than that detected by EC-meter for both soils and ii) travel times for peak concentration were more less identical for two different monitoring techniques. The first result can be explained by ion exchange between Zn and other cations initially present in the soil particles since ICP analysis showed a significant amount of Ca, Mg ions in the effluent. From the second result, we found that retardation effect was not present in these soils due to strong cation exchange capacity of Zn ion over other cations since we did not apply a solution containing more adsorptive cations such as Al. The result of batch test also showed high distribution coefficients (K$_{d}$) for two soils supporting the dominant ion exchange phenomena. Based on the retardation factor obtained from the Kd, we predicted the BTC using CDE model and compared with the BTC of Zn concentration obtained from ICP The predicted BTC, however, disagreed with the monitored in terms of travel time and magnitude of the peak concentrations. The only way to describe the prominent decrease of Zn ion was to introduce decay or sink coefficient in the CDE model to account for irreversible decrease of Zn ions in liquid phase.e.

  • PDF