• Title/Summary/Keyword: EMM

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Seasonal Distribution of T Serotyping and emm Genotyping of Group A Streptococci Obtained from Children with Streptococcal Infections in Masan, Korea, 2003~2004 (2003~2004년 경남 마산 지역에서 분리된 A군 연쇄구균의 T 혈청형과 emm 유전자형의 계절별 분포)

  • Jeon, Ho-Sang;Park, Hwa-Jin;Lee, Hee-Joo;Ma, Sang-Hyuk;Cha, Sung-Ho
    • Pediatric Infection and Vaccine
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    • v.12 no.1
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    • pp.52-60
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    • 2005
  • Purpose : The aim of this study is to know seasonal distribution of group A streptococci obtained from one center using emm genotyping and T serotyping in Masan from 2003 through 2004. Methods : Among children who visited the Changwon Fatima Hospital at Masan, Korea from June 2003 through February 2004, 100 patients who had clinical findings of acute pharyngitis, scarlet fever, and cellulitis were confirmed as GAS by culture, and were enrolled in our study. All obtained GAS were sent to the WHO Collaborative Center for Reference and Research on Streptococci, University of Minnesota, Minneapolis for T serotyping and emm genotyping. We classified these results again according to seasonal and disease's entities. Results : 19 different T serotypes was typed. T4(27.5%), T1(17.6%), T6(13.7%), and T12(13.7%) serotypes were relatively common in summer, while T4(28.3%), T12(15.2%), and T12/B3264(8.7%) were common in winter. T4 and T12 were persistent all year around. Distribution of T serotypes in 89 patients with pharyngotonsillitis were T4(26.7%), T12(14.0%), T1(12.8%), and T6(11.6%) in order of frequency. 15 different emm genotypes was typed. The number of emm 1, emm 6, emm 9, and emm 44 genotypes decreased or disappeared in winter, and the number of emm 3, emm 12, and emm 89 genotypes increased or reappeared in winter. Conclusion : Because T serotyping and emm genotyping are useful tools for evaluating epidemiology and pathogenesis of group A streptococci, we should monitor these strains every year, and should serotype and genotype GAS obtained from the invasive streptococcal infections.

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Epidemiological Characterization of Group A Streptococci Using emm Genotyping from Throat Cultures in Patients with Acute Pharyngitis in Children (소아과 의원을 방문한 급성인두염 환자의 인후배양과 emm 유전자형을 이용한 A군 연쇄구균의 역학조사)

  • Jung, Hyun Ju;Lee, Nam Yong;Kwon, Oh-Young;Maeng, Kook Young;Kim, Sunjoo
    • Pediatric Infection and Vaccine
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    • v.10 no.2
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    • pp.178-185
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    • 2003
  • Purpose : Group A streptococci(GAS) was isolated from the patients with acute pharyngitis. Epidemiological studies using T typing and emm genotyping was performed for GAS and compared with the results of the carriers. Methods : Throat cultures were taken from 246 children(123 boys, 123 girls) from November, 2001 to May, 2002 who visited a pediatrician's office located in Jinju, Gyeongnam province. T types were identified with slide agglutination and emm genotypes were identified with DNA sequencing after amplification of emm genes. Results : One hundred thirty(52.8%) out of 246 children yielded beta-hemolytic streptococci, of which 96.1% were group A. Children from 4 to 7 years old comprised 70.4% of the GAS positive group. T12 were the most common(35.2%) and T non-typeable strains were the next(30.4%). emm12 was most frequent(28.5%), and emm75(18.7%), emm22(13.0%), emm2(12.2%), and emm8(8.1%) were relatively common. Conclusion : Since GAS is so highly prevalent in acute pharyngitis, indeed being half of the population, good clinical practice dictates the systematic employment of throat culture for acute pharyngitis before prescribing antibiotics in a pediatric setting. The distribution of the T antigens and emm genes showed similar pattern between the acute pharyngitis and the carriers.

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Differences in T Serotypes and emm Genotypes of Group A Streptococci Obtained from Invasive and Non-invasive Streptococcal Infections (침습적 및 비침습적 감염 환자에서 분리된 A군 연구균의 T 혈청형과 emm 유전자형의 비교 연구)

  • Hahn, Wonho;Kim, Sejin;Ko, Hansoek;Jung, Sajun;Cha, Sungho;Lee, Heejoo;Lee, Kyungwon
    • Pediatric Infection and Vaccine
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    • v.13 no.2
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    • pp.106-114
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    • 2006
  • Purpose : Studying the serotypes and emm genotype of group A streptococci(GAS) hold a key role in the investigation of epidemiology, pathogenesis, and resistance to antibiotics. We planed to find out the possible differences in serotypes and genotypes between the invasive and the non-invasive GAS infection. Methods : We obtained 39 isolates from the patients hospitalized in 2004 with the diagnosis of invasive GAS infectious diseases in the Severance Hospital, Yonsei University. We sent the isolates to the WHO Collaboratory Center in University of Minnesota and analyzed T serotypes and emm genotypes. These results were compared with non-invasive GAS infections in our hospital. Results : Compared this data with the results of 2003 to 2004, T2/28, T3, T5/27/44, T9 and NT were more prevalent. The NT showed statistically significant difference(P=0.019). The emm 3, emm 9, emm 18, emm 44 and emm provision type STG485 were more frequent genotypes compared with the study in 2003~2004, relatively. The emm provision type STG485 had statistically significant difference(P=0.000). The incidence of T12 plus T4, known as erythromycin(EM) resistant serotypes, was as low as 17.9% in this study, compared with those of non-invasive strains. Conclusion : The incidence of EM-resistant strains is supposed not to be higher in invasive GAS infection. We could find out possible higher incidence of rheumatogenic strains in the invasive GAS infections. It seems to be important to have an effort on studying of serotyping and genotyping for the monitoring of strains and to know the epidemiologic characteristics.

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Micro Groove Machining for Electrochemical Micro-Machining (전기화학 가공을 이용한 마이크로 홈 가공)

  • 김영민;이은상
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.1844-1847
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    • 2003
  • Electrochemical micro-machining(EMM) is used to achieve a desired workpiece surface by dissolving the metal workpiece with an electrochemical reaction. This machining method can be applied to metal that is difficult to machining using other methods. The workpiece dissolves when it is positioned close to the tool electrode in electrolyte and current is applied. This aim of this work is to develop electrochemical micro-machining(EMM) technique for micro groove shape by establishing appropriate electrochemical parameters of machining

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An EMM Approach to Derive an Energy Integral for the Direct Method of Stability Analysis in Power Systems

  • Moon, Young-Hyun
    • Journal of Electrical Engineering and information Science
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    • v.1 no.1
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    • pp.58-69
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    • 1996
  • This paper presents a new approach to derive an energy integral based on an Equivalent Mechanical Model(EMM), which is developed by introducing imaginary springs for line resistances. The proposed EMM shows that phasor currents and voltages are directly analogous to the two-dimensional force and displacement vectors, respectively. Through rigorous energy analysis of the proposed EMM, an exact energy integral expression is derived for multimachine systems, and several useful theorems are developed to derive an energy integral for power systems with detailed generator models the energy integral exactly reflects the internal resistance, saliency and flux-decaying effects of the generator. Finally, an illustrative example is given for a multimachine system adopting the Eq'-model for generators, which shows that the consideration of a detailed generator model does not aggravate the complicacy of the direct method of stability analysis in multimachine systems.

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A Study on Voltage Collapse Mechanism in Electric Power Systems (전력계통에서의 전압붕괴 매카니즘에 관한 연구)

  • Kim, Do-Hyung;Ryu, Heon-Su;Moon, Young-Hyun;Choi, Byoung-Kon;Park, Jung-Do
    • Proceedings of the KIEE Conference
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    • 2001.07a
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    • pp.171-174
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    • 2001
  • In this paper, an EMM(Equivalent Mechanical Model) is developed to explain the voltage collapse mechanism by reflecting the effects of reactive powers. The proposed EMM exactly represents the voltage instability mechanism described by the system equations. By the use of the EMM model the voltage collapse mechanism has been illustrated by showing the exactness of the results. It is also discussed a system transform in technique to eliminate the resistance component of the Thevenin equivalent impedance for practical applications.

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A Study on Voltage Collapse Mechanism using Equivalent Mechanical Model

  • Kim, Do-Hyung;Ryu, Heon-Su;Lee, Jong-Gi;Moon, Young-Hyun
    • KIEE International Transactions on Power Engineering
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    • v.12A no.1
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    • pp.6-14
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    • 2002
  • In this paper, an EMM(Equivalent Mechanical Model) Is developed to explain the voltage collapse mechanism by reflecting the effects of reactive powers. The proposed EMM exactly represents the voltage instability mechanism described by the system equations. By the use of the EMM model, the voltage collapse mechanism has been illustrated by showing the exactness of the results. The stable region has been investigated with a reactive-power-controlled two-bus system, which shows that special alerts are required when the system operates with leading power factor. It is also discussed a system transform technique to eliminate the resistance component of the Thevenin equivalent impedance for practical applications. Finally, the results adopting the proposed method fur sample systems which were transformed are listed

An Enhanced AAA Mechanism in Active Netwok (능동 네트워크에서의 향상된 AAA 구조방안)

  • 이효성;김기천;김인수
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10c
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    • pp.544-546
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    • 2004
  • 본 논문에서는 액티브 라우터를 이용 Enhanced Mobility Management(EMM) 알고리즘을 사용 하는 이동성관리 구조에서, 이동노드의 신뢰성 확보를 위한 AAA프레임워크와의 연동모형을 전제로 한다. 액티브 라우터로 구성된 능동망내에서 액티브 캡슐에 의한 EMM모듈의 운용시 발생할 수 있는 노드의 망 접속인증과 이동노드로의 인증모형을 기존의 AAA구조와 연계하여 해결하는 방안을 제시한다. 지역등록시 발생하는 통신지연 문제를 해결하기위한 강화된 AAA구조와의 연동기법을 설계하여 보다 더 부드럽고 안전한 핸드오프 과정을 제안한다.

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Characteristics of Stochastic Volatility in Korean Stock Returns (우리나라 주식수익률의 확률변동성 특성에 관한 연구)

  • Chang, Kook-Hyun
    • The Korean Journal of Financial Management
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    • v.20 no.1
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    • pp.213-231
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    • 2003
  • This paper uses the Efficient Method of Moments(EMM) of Gallant and Tauchen to estimate continuous-time stochastic volatility diffusion model for the Korean Composite Stock Price Index, sampled daily over $1995\sim2002$. The estimates display non-normality of stock index return, leptokurtic distribution, and stochastic volatility. Funker, this study suggests that two factor stochastic volatility model will be more desirable than one factor stochastic volatility model to estimate daily Korean stock return and also suggests that the stochastic volatility diffusions should allow for Poisson jumps of time-varying intensity.

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