• Title/Summary/Keyword: EMRA

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USN metadata management agent using IoT-based EMRA

  • Lee, Jong-Sub
    • International Journal of Internet, Broadcasting and Communication
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    • v.14 no.4
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    • pp.96-103
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    • 2022
  • In this paper, we define EMRA-based USN metadata to describe sensor device, sensor node, and sensor network information at the application level. And the proposed method for effectively storing and retrieving USN metadata based on EMRA uses agent technology. As the sensor metadata proposed in this paper is based on SensorML, interoperability can be maintained in the USN environment, and the metadata management system can be directly utilized for metadata management in USN middleware or applications.

Mobile Cloud System based on EMRA for Inbody Data

  • Lee, Jong-Sub;Moon, Seok-Jae
    • International Journal of Advanced Culture Technology
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    • v.9 no.3
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    • pp.327-333
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    • 2021
  • Inbody is a tool for measuring health information with high reliability and accuracy to analyze body composition. Unlike the existing method of storing/processing and outputting data on the server side, the health information generated by InBody requires accurate support for health sharing and data analysis services using mobile devices. However, in the process of transmitting body composition measurement information to a mobile service, a problem may occur in data transmission/reception processing. The reason for this is that, since the network network in the cloud environment is used, if the connection is cut off or the connection is changed, it is necessary to provide a global service, not a temporary area, focusing on the mobility of InBody information. In addition, since InBody information is transmitted to mobile devices, a standard schema should be defined in the mobile cloud environment to enable information transfer between standardized InBody data and mobile devices. We propose a mobile cloud system using EMRA(Extended Metadata Registry Access) in which a mobile device processes and transmits body data generated in the inbody and manages the data of each local organization with a standard schema. The proposed system processes the data generated in InBody and converts it into a standard schema using EMRA so that standardized data can be transmitted. In addition, even when the mobile device moves through the area, the coordinator subsystem is in charge of providing access services. In addition, EMRA is applied to the collision problem due to schema heterogeneity occurring in the process of accessing data generated in InBody.

Distributed Data Platform Collaboration Agent Design Using EMRA

  • Park, Ho-Kyun;Moon, Seok-Jae
    • International Journal of Internet, Broadcasting and Communication
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    • v.14 no.2
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    • pp.40-46
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    • 2022
  • Recently, as the need for data access by integrating information in a distributed cloud environment increases in enterprise-wide enterprises, interoperability for collaboration between existing legacy systems is emphasized. In order to interconnect independent legacy systems, it is necessary to overcome platform heterogeneity and semantic heterogeneity. To solve this problem, middleware was built using EMRA (Extended MetaData Registry Access) based on ISO/IEC 11179. However, the designed middleware cannot guarantee the efficiency of information utilization because it does not have an adjustment function for each node's resource status and work status. Therefore, it is necessary to manage and adjust the legacy system. In this paper, we coordinate the correct data access between the information requesting agent and the information providing agent, and integrate it by designing a cooperative agent responsible for information monitoring and task distribution of each legacy system and resource management of local nodes. to make efficient use of the available information.

Effects of Korean red ginseng on T-cell repopulation after autologous hematopoietic stem cell transplantation in childhood cancer patients

  • Kyung Taek Hong;Yeon Jun Kang;Jung Yoon Choi;Young Ju Yun;Il-Moo Chang;Hee Young Shin;Hyoung Jin Kang;Won-Woo Lee
    • Journal of Ginseng Research
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    • v.48 no.1
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    • pp.68-76
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    • 2024
  • Background: Although the survival outcomes of childhood cancer patients have improved, childhood cancer survivors suffer from various degrees of immune dysfunction or delayed immune reconstitution. This study aimed to investigate the effect of Korean Red Ginseng (KRG) on T cell recovery in childhood cancer patients who underwent autologous hematopoietic stem cell transplantation (ASCT) from the perspective of inflammatory and senescent phenotypes. Methods: This was a single-arm exploratory trial. The KRG group (n = 15) received KRG powder from month 1 to month 12 post-ASCT. We compared the results of the KRG group with those of the control group (n = 23). The proportions of T cell populations, senescent phenotypes, and cytokine production profiles were analyzed at 1, 3, 6, and 12 months post-ASCT using peripheral blood samples. Results: All patients in the KRG group completed the treatment without any safety issues and showed a comparable T cell repopulation pattern to that in the control group. In particular, KRG administration influenced the repopulation of CD4+ T cells via T cell expansion and differentiation into effector memory cell re-expressing CD45RA (EMRA) cells. Although the KRG group showed an increase in the number of CD4+ EMRA cells, the expression of senescent and exhausted markers in these cells decreased, and the capacity for senescence-related cytokine production in the senescent CD28- subset was ameliorated. Conclusions: These findings suggest that KRG promotes the repopulation of CD4+ EMRA T cells and regulates phenotypical and functional senescent changes after ASCT in pediatric patients with cancer.