• Preventive Nutrition and Food Science
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• v.20 no.1
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• pp.43-51
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• 2015

${\varepsilon}$-Polylysine (EPL) is used as a natural preservative in food. However, few studies have been conducted to assess the beneficial functions of dietary EPL. The purpose of this study was to elucidate the mechanism underlying the inhibition of neutral and acidic sterol absorption and hepatic enzyme activity-related fatty acid biosynthesis following EPL intake. EPL digest prepared using an in vitro digestion model had lower lipase activity and micellar lipid solubility and higher bile acid binding capacity than casein digest. Male Wistar rats were fed an AIN-93G diet containing 1% (wt/wt) EPL or L-lysine. After 4 weeks of feeding these diets, the marked decrease in serum and liver triacylglycerol contents by the EPL diet was partly attributed to increased fecal fatty acid excretion. The activities of hepatic acetyl-coenzyme A carboxylase and glucose-6-phosphate dehydrogenase, which are key enzymes of fatty acid biosynthesis, were enhanced in rats fed EPL diet. The increased fatty acid biosynthesis activity due to dietary EPL may be prevented by the enhancement of fecal fatty acid excretion. The hypocholesterolemic effect of EPL was mediated by increased fecal neutral and acidic sterol excretions due to the EPL digest suppressing micellar lipid solubility and high bile acid binding capacity. These results show that dietary EPL has beneficial effects that could help prevent lifestyle-related diseases such as hyperlipidemia and atherosclerosis.

• Nutrition Research and Practice
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• v.13 no.4
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• pp.295-301
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• 2019

BACKGROUND/OBJECTIVES: Consumption of cholesterol-rich foods, such as eggs, has a minimal effect on circulating cholesterol levels in healthy humans. To gain insight, we investigated whether phospholipids rich in eggs (EPL) interfere with intestinal cholesterol absorption in vivo. MATERIALS/METHODS: To investigate the acute effect of EPL on intestinal cholesterol absorption, male C57BL/6J mice were orally administered with 6, 11, or 19 mg of EPL for three days. We also tested the effect of chronic EPL consumption on cholesterol metabolism in the small intestine and the liver in mice with diet-induced hypercholesterolemia. Male C57BL/6J mice were fed a high fat/high cholesterol (HF/HC; 35% fat, 0.25% cholesterol, w/w) diet for 4 weeks to induce hypercholesterolemia, and subsequently the mice were either fed 0, 0.4 or 0.8% (w/w) of EPL for 6 weeks. RESULTS: Intestinal cholesterol absorption was significantly decreased by the highest dose of acute EPL administration compared to control. Chronic EPL supplementation did not significantly alter intestinal cholesterol absorption nor plasma levels of total cholesterol and low-density lipoprotein cholesterol. In the small intestine and the liver, EPL supplementation minimally altered the expression of genes which regulate cellular cholesterol levels. CONCLUSION: Although chronic EPL consumption was not able to counteract hypercholesterolemia in HF/HC-fed mice, acute EPL administration decreased intestinal cholesterol absorption. This study provides in vivo evidence that acute administration of PLs in eggs prevent cholesterol absorption in the intestine, suggesting a mechanism for a minimal effect of egg consumption on circulating cholesterol levels.

• Proceedings of the Korean Society of Computer Information Conference
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• 2018.07a
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• pp.405-408
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• 2018

이 연구의 목적은 기존 EPL 관련 연구들을 조사 및 수집하여 메타분석을 통해 초등학생의 고등사고력 향상에 미치는 전체 효과 크기의 산출과 다양한 변인에 따른 효과크기를 확인하는 것이다. 그래서 이 연구로 초등학생의 고등사고력 및 다양한 요인들에 대한 EPL 교육의 실제적 효과를 객관적으로 확인하고 일반화하였다. 이 연구의 결과는 1)EPL을 활용한 교육이 초등학생들의 고등사고력을 크게 향상시키는 교수학습 도구임이 확인되었고, 2) EPL을 활용한 교육은 창의적 사고력, 논리적 사고력 등의 향상에 크게 도움이 되는 것으로 확인되었으며, 3) App Inventor, Scratch, Dolittle 등이 고등사고력 향상에 미치는 효과가 큰 것으로 확인되었다.

• Journal of The Korean Association of Information Education
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• v.21 no.6
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• pp.691-699
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• 2017

Along with the increased significance of SW education in the 2015 revision curriculum, SW education using various educational methods and tools is being performed, and teaching and learning contents using SW education tools are continuously being developed. In this paper, we analyzed pre-service teachers' EPL contents preference types, preferred development subjects, and their relationship with pre-service teachers based on the analysis conducted after their EPL class session in which its results were assortatively analyzed by department, letter grade, and type. The result signified a clear difference in development subject and types among the departments, and it also showed a difference in development subject and its recipients among the types. However, there was no difference between development subject and type among the letter grade. This will provide a feedback on EPL classes and help develop EPL-related curricula as well as its application.

• The Journal of Korean Association of Computer Education
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• v.14 no.3
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• pp.25-36
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• 2011

The purpose of this study was to analyze the effects of educational programming language(EPL) using the meta-analysis method. In order to achieve the purpose of this study, t-test and F-test were performed for the effect size differences between the variables. The results of the study were as follows: First, EPL turned out to be highly effective in improving learning effects. The total mean of effect size was as big as 1.01 and the value of $U_3$ was 84.38%. EPL increased the learning effect by 34.38% compared with the control group. Second, the moderator variables such as subject, publication type, and learner's school age there was no statistically significant differences. By designing the experiment nonequivalent control group pretest-posttest design showed statistically significant effect size compared with single group pretest-posttest design. Third, the mean effect sizes of the dependent variables were as follows: Creativity 1.90, problem solving ability 1.25, logical thinking ability 1.18, learning motivation 0.81, and achievement 0.59. EPL showed positive effect than traditional teaching and learning method comprehensively.

• The Journal of Korean Association of Computer Education
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• v.14 no.1
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• pp.1-12
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• 2011

Educational Programming Language has been reported to expand thinking ability and to give help in creative problem solving ability by numerous researches. Researchers are verifying the educational effects of EPL by applying it to various area, but researches in effective application of EPL is yet incomplete. Thus, for effective application of EPL, this research has verified the project completing ability depending on studying style targeted to college senior students. As results of verification, first, the results showed significant differences in project completing abilities depending on information processing methods, and learners who preferred self-reflecting introspection showed high scores. Second, in learning style the divergers showed the highest scores. This research suggested the necessity of guidance and detailed planning of self-reflecting introspective activity in ideas that would be realized by learners through searching for factors that could enhance the degree of project completion in programming learning using EPL.

• Journal of The Korean Association of Information Education
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• v.15 no.1
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• pp.85-91
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• 2011

Programming training in informatics education have the means that algorithm design and problem solving. However, Because learning and using programming tools that should be done first, elementary school students learning the programming tools that are interested in the process has been reduced. But programming with using an Educational Programming Language(EPL) can show results directly and coding with a drag & drop method that keeps the elementary students' interests for programming. Now that, the students are possible to enhance their creativity and reasoning skills. Therefore, through the result of this study show how to apply the EPL in the elementary information classes and comparing with before this study and after the study, we analyzed to applicate prosperity of EPL.

• 한국정보교육학회:학술대회논문집
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• 2010.01a
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• pp.83-88
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• 2010

본 논문은 다양한 사고력 향상을 위한 문제 중심의 이야기를 만들어 스크래치 EPL 프로그래밍 교육과정에 접목시켜 전통적 수업방식인 시범, 실습 프로그래밍 교육과정과 비교하여 문제해결력, 프로그래밍 학습에 대한 흥미도를 통하여 새로 개발한 문제 중심의 스토리텔링 기법을 이용한 스크래치 EPL 프로그래밍 교육과정의 효과를 분석한다. 이를 통해서 학생들에게 흥미로운 이야기에 문제상황을 가미한 스크래치 EPL 프로그래밍 교육과정이 학생들의 문제해결력 및 흥미도를 향상 시키는 내용임을 검증한다.

• Journal of The Korean Association of Information Education
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• v.24 no.3
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• pp.233-241
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• 2020

This study has developed and applied an elementary EPL education program centered on execution time as an educational method for improving Computational thinking of elementary school students, and then its effect has been verified. The education program was developed based on the results of preliminary demand analysis conducted on 48 elementary school students. In order to verify the effectiveness of the education program, 25 students were asked to participate in the class of elementary school students on a seven hours for six days. Using the "Korea Bebras Challenge 2018", educational effects were analyzed through the results of pre- and post-mortem examinations, and the analysis showed that elementary EPL education centered on performance time was effective in improving computational thinking of elementary school students

• Journal of The Korean Association of Information Education
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• v.12 no.1
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• pp.77-88
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• 2008

A programming education has favorable influence on creative / logical thinking and problem solving ability of students. However, students typically have to spend too much effort in learning basic grammar and the usage model of programming languages, which negatively affect their eagerness in learning. In this respect, we proposed to apply the 'Scratch' using the Creative Problem Solving(CPS) Teaching Model; Scratch is an easy-to-learn and intuitive Educational Programming Language(EPL) that helps improving the problem solving ability of the class. Then we verified the effect of Scratch EPL through the design of both pretest and posttest for a subject group. In summary, the CPS based Scratch EPL was shown to significantly improve the problem solving ability and also help them develop favorable attitude in programming.