• YAKHAK HOEJI
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• v.51 no.1
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• pp.35-43
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• 2007

To investigate the immunomodulatory roles of cyclic AMP (CAMP) on macrophage- and T lymphocyte-mediated immune responses, CAMP elevating agents were employed and carefully re-examined under the activation conditions of the cells. Various inhibitors tested dose-dependently blocked tumor necrosis factor (TNF)-${\alpha}$ production with IC$_{50}$ values ranged from 0.04 to 300 ${\mu}$M. Of the inhibitors, cAMP-elevating agents showed lower cytotoxicity assessed by lactate dehydrogenase (LDH) release, suggesting less toxic and more selective. In particular co-treatment of dbcAMP with a protein kinase C inhibitor staurosporine displayed the synergistic inhibition of TNF-${\alpha}$ production. The modulatory effect of dbcAMP on TNF-${\alpha}$ and nitric oxide (NO) was significantly affected by treatment time of dbcAMP. Thus, post-treatment of dbcAMP (three hours before LPS) abrogated dbcAMP's inhibitory activity and rather enhanced TNF-${\alpha}$ level up to 60%. In contrast, additional NO production was shown at the co-treatment of dbcAMP with LPS. Unlike simultaneous treatment of phorbol 12-myristate 13-acetate (PMA) and interferon (IFN)-${\gamma}$co-treatment, the combination of dbcAMP with other NO-inducing stimuli did not show drastic overproduction of NO. cAMP elevating agents also diminished splenocyte proliferation stimulated by concanavalin (Con) A, phytohemaglutinin A (PHA) and lipopolysaccharide (LPS). In addition, dbcAMP but not rolipram strongly suppressed CD8$^+$ T cells (CTLL-2). Finally, cAMP elevating agents were differentially involved in regulating CD98-mediated cell-cell adhesion. Thus, dbcAMP and rolipram significantly enhanced the cell-cell adhesion, whereas forskolin blocked. Therefore, our results suggest that CAMP elevating agents participate in various immune responses mediated by macrophages and T cells with a different fashion depending on cellular environments and activation signals.

• Journal of Korea Foundry Society
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• v.18 no.5
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• pp.450-461
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• 1998

The optimal reheating conditions to apply the thixoforging and semi-solid die casting process were investigated by changing the reheating time, the holding time, the reheating temperatures, the capacity of the induction heating system, and the adiabatic material size. In the case of solid fraction fs=50% (for semi-solid die casting), the microstructure of SSM (specimen size:$d76{\times}l90$) at the condition of the first elevating time of 4 min, holding time of 1 min and holding temperature of $350^{\circ}C$, the second elevating time of 3 min, holding time of 3 min and holding temperature of $575^{\circ}C$, the third elevating time of 1 min, holding time of 2 min and holding temperature of $584^{\circ}C$, capacity of Q=8.398KW is obtained with globular microstructure and finest. In addition, in the case of solid fraction fs=55% (for thixoforging), the SSM (specimen size:$d76{\times}l90$) at the condition of the first elevating time of 4 min, holding time of 1 min and holding temperature of $350^{\circ}C$, the second elevating time of 3 min, holding time of 3 min and holding temperature of $570^{\circ}C$, the third elevating time of 1 min, holding time of 2 min and holding temperature of $576^{\circ}C$, capacity of Q=12.04KW is obtained with the finest globular microstructure. We saw that the most important factor in a three-step reheating process is the final holding time.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.1503-1510
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• 2011

The dropper length calculation method about the normal same encumbrance spans is well known independent to whether the pre-sag is given or not. But, the dropper length calculation method for the elevating span which consists in the end area of a tensioning section and normally consists with overlaps is not well known. In this study, firstly, we investigate the dropper length calculation method about the elevating span whether the insulator is contained in or not, we also recognize the effect of dropper length due to the change of the take-off point. Secondly, we very this calculation method with a catenary sample data and check again with Gyeongbu HSL design data.

• Journal of Sasang Constitutional Medicine
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• v.21 no.2
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• pp.153-162
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• 2009

1. Objectives : The purpose of this rase study is to evaluate the superiority of Sasang constitutional diagnosis and treatment in skin disease compared with western medicine and is to notify the importance of elevating requsite qi(保命之主) in treatment of skin disease. 2. Method : We compared to remedical value in two case. One is to use herbal medicine as well as routine antibiotic treatment. The other one is to use only herbal medicine. Antibiotics was focused on attacking the pathogen and herbal medicine was focused on elevating requsite qi(保命之主). 3. Result and conclusions : In result, the one using only herbal medicine showed satisfactory progress and predominant remedical value compared with one using herbal medicine and routine antibiotic. So It is necessary to approach skin disease in view of elevating requsite qi(保命之主).

• Journal of Chest Surgery
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• v.26 no.10
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• pp.743-748
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• 1993

Alterations in thyroid function test results are frequently seen in patients with nonthyroidal illness & correlate with the severity of the illness & prognosis. We studied thyroid hormone changes in 14 patients received cardiopulmonary bypass[CPB]. All patients were biochemical euthyroidism preoperatively. TSH[Thyroid Stimulating Hormone] level reached its nadir[0.46 $\pm$ 0.11 ulU/ml, P<0.0005] at 12 hours after the start of CPB & showed elevating pattern to the preoperative level thereafter. FT4[Free Thyroxine] reached to its nadir[10.16$\pm$ 1.17 pmol/L, P<0.01] at POD[Post Operative Day] #4 & reached to the preoperative level at POD #7. Mean serum TSH & FT4 concentration were within normal limits[P>0.25] during CPB & thereafter. TT3[Total Triiodothyronine] reached to its nadir[38.6 $\pm$ 8.4 ng/dl, P<0.001] at 30 minutes after the start of CPB & remained low[P<0.05] throughout the study period. The patients whose recovery was uneventful[Group I] had higher serum TSH, TT3 levels[P<0.05] than who had complications or died[Group II]. Group I showed the elevating pattern of TSH, TT3 at POD #4, but Group II failed to show such elevating pattern. In Group I, FT4 was within normal limits[P>0.5] throughout the study period, and also within normal limits[P>0.1] in Group II.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.9
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• pp.1444-1450
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• 2003

The fatigue life and tensile strength of JLF-1 steel (Fe-9Cr-2W-V-Ta) and its TIG weldment were investigated at the room temperature and $400^{\circ}C$. Four kinds of test specimens, which associated with the rolling direction and the TIG welding direction were machined. The base metal of JLF-1 steel represented almost anisotropy in the tensile properties for the rolling direction. And the base metal of JLF-1 steel showed lower strength than that of TIG weldment. Also, the strength of all materials entirely decreased in accordance with elevating test temperature. Moreover, the fatigue limit of weld metal was largely increase than that of base metal at both temperatures. The fatigue limit of JLF-1 steel decreased in accordance with elevating test temperature. The fatigue limit of JLF-1 steel decreased in accordance with elevating test temperature. The SEM fractography of tensile test specimen showed conspicuous cleavage fracture of a radial shape. In case of fatigue life test specimen, there were so many striations at crack initiation region, and dimple was observed at final fracture region as a ductile fracture mode.

• Journal of the Korean Society of Clothing and Textiles
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• v.27 no.5
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• pp.582-587
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• 2003

To examine the effect of heat treatment temperature in finishing process on PET/PBT Fabric, PET/PBT Fabrics were treated at different relaxing temp., pre-set temp., and final-set temp.. The dimensions such as thickness and density were measured, and the handles were evaluated by Kawabata system. In relaxing which was wet heat treatment, thickness and bulkiness were increased, and NUMERI, FUKURAMI, SOFUTOSA, and THV also were increased but KOSHI was decreased with elevating temperature. With elevating pre-set temp., thickness and bulkiness were decreased, but KOSHI was increased. NUMERI, FUKURAMI, SOFUTOSA, and THV were the best at 180$^{\circ}C$ pre-set treatment. In final-set which was dry heat treatment like pre-set, thickness, bulkiness, NUMERI, HUKURAMI, SOFUTOSA, and THV were decreased, but KOSHI value was increased with elevating temperature. Therefore the best heat treatment condition was 130$^{\circ}C$ relaxing, 180$^{\circ}C$ pre-set, and 160$^{\circ}C$ final-set. And the handle of PET/PBT Fabric was affected much more by relaxing temp. than pre-set temp. and final-set temp.

• Journal of the Korean Ceramic Society
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• v.15 no.2
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• pp.72-78
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• 1978

The vapor pressure of the high melting point oxides, MgO, $Cr_2O_3$, and $MgCr_2O_4$ were measured over the temperature range 1300 to 175$0^{\circ}C$ under vacuum <$10^{-5}$ torr by the Langmuir and the Knudsen method. The Langmuir vapor pressure was increased with elevating temperature and with increasing porosity of the specimen. The difference between the vapor preseures measured by the Langmuir and the Knudsen method was decreased with elevating temperature and the Langmuir vapor pressure finally reached the Knudsen vapor pressure at the melting point when extrapolated. The vapor pressure of other important oxides with high melting points, i.e., $Al_2O_3$, $ThO_2$, $Yb_2O_3$ and $Y_2O_3$ were cited from the references. The Langmuir and the Knudsen vapor pressure of these oxides also showed the same results, i.e., they showed the same value at their melting points.

• Journal of Korean Medical classics
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• v.21 no.3
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• pp.285-296
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• 2008

"The Golden Mirror of Medicine(醫宗金鑑)" is a very famous medical book. It was compiled by the medical officers of the Cheong(淸, Qing) Dynasty, especially headed by Ogyeom(吳謙, Wuqian). "The Elimination ＆amp; Supplement about the Famous Prescription Comments(刪補名醫方論)"that forms one part of "The Golden Mirror of Medicine(醫宗金鑑)", is a collection of famous notes about important prescriptions. Many parts of "The Elimination ＆amp; Supplement about the Famous Prescription Comments(刪補名醫方論)" were quoted from "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)". The first part of the vol. Ⅱ of "The Elimination ＆amp; Supplement about the Famous Prescription Comments(刪補名醫方論)"mainly describes about the prescriptions of elevating Yanggi[升陽], which were invented by Igo(李杲, Ligao), a famous physician of the Geum(金, Jin) Dynasty. The treatments were five and three of them were quoted from "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)". The basic rule of herbal combination of these prescriptions is a combination of herbs of strengthening-gi[補氣] and dispersing herbs[發散藥]. If the dispersing herbs[發散藥] is used with the herbs of strengthening-gi[補氣藥], they elevate Yanggi(陽氣) together.

• Journal of the Korea Fashion and Costume Design Association
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• v.10 no.3
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• pp.111-126
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• 2008

This article aims to discover the current status and appropriate way to research Gyubang craft, expecting its development and preservation, and elevating it to Korea's unique artistic textile culture. It also searches improved methods for Gyubang craft as the following: First, in order to avoid confusions about Gyubang craft, appropriate concepts and definitions of Gyubang craft must be settled through a discussion among experts. Second, by activating economic activities at lower ratio, among purposes of Gyubang craft, achievements must be elevated. Third, in order to settle down the difficulties of Gyubang craft, a variety of methods such as effective sewing machines and manufacturing techniques as well as providing materials at a reasonable price, considering practical ways through diversifying products, elevating the economy of crafts, exploring sales routes, improving educational contents, and expanding educational places must be facilitated. Fourth, for nurturing talented and excellent human resources in the area of Gyubang craft, the followings should be considered: diversifying contents of education, developing textbooks, improving instructors' quality, providing reasonable cost of education, educating on the utilization and application of Gyubang craft, introducing efficient teaching methods through textbooks and multimedia, awarding 'certificates' to trainees, and permitting certificate holders' to instruct Gyubang craft. Finally, it is convinced that the achievement of production, pride of preserving tradition, pleasure of procedural work, economic activities as experts, and sales of products will be reinforced, and the population for Gyubang craft is also expected to increase. By elevating Gyubang craft into Korea's traditional textile art, Korea's global competitiveness in the area of textile should be strengthened.