• 한국수자원학회논문집
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• 제51권2호
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• pp.165-174
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• 2018

시계열 데이터를 활용하는 모형은 신뢰할 수 있는 자료를 확보한 경우에는 모형 구축이 용이하고 예측 선행 시간 확보를 위해 신속한 모의가 가능한 장점 때문에 규모가 작은 하천의 홍수예측 모형으로 고려할 수 있다. 이 중 Transfer Function Noise (TFN) 모형은 이탈리아, 영국 등 해외에서는 1970년대부터 시간단위 자료를 이용한 하천유량 예측에 적용되었으나, 우리나라에서는 주로 일 단위 혹은 월 단위의 하천유량 모의에 적용되었다. 국내 수문 자료의 품질 향상으로 그동안 축적된 수문자료를 통해 시간단위 자료를 이용한 홍수예측 모형의 구축 기반이 갖추어졌다. 본 연구의 목적은 소규모 하천을 대상으로 외생변수의 반영이 가능하고 동적시스템과 오차항을 결합하여 예측 오차를 줄이는데 용이한 TFN 모형을 구축하고 그 적용성을 검토하는 것이다. 이를 위해 1시간 단위 자료를 이용하여 TFN 모형을 구축하였으며 구축된 모형을 이용한 홍수 예측 결과를 홍수예보 실무에 활용 중인 저류함수모형의 홍수 예측 결과와 비교하였다. 비교 결과 홍수사상에 따라 TFN 모형과 저류함수 모형이 각각 더 나은 결과를 보이는 사상이 있었으며, 실무에서 TFN 모형을 홍수예측 모형으로 활용할 수 있을 것으로 판단하였다.

• Nutrition Research and Practice
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• 제5권3호
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• pp.253-259
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• 2011

The rapid rise in the incidence of obesity has emerged as one of the most pressing global public health issues in recent years. The underlying etiological causes of obesity, whether behavioral, environmental, genetic, or a combination of several of them, have not been completely elucidated. The obesity epidemic has been attributed to the ready availability, abundance, and overconsumption of high-energy content food. We determined here by Pearson's correlation the relationship between food type consumption and rising obesity using the loss-adjusted food availability data from the United States Department of Agriculture (USDA) Economic Research Services (ERS) as well as the obesity prevalence data from the Behavioral Risk Factor Surveillance System (BRFSS) and the National Health and Nutrition Examination Survey (NHANES) at the Centers for Disease Control and Prevention (CDC). Our analysis showed that total calorie intake and consumption of high fructose com syrup (HFCS) did not correlate with rising obesity trends. Intake of other major food types, including chicken, dairy fats, salad and cooking oils, and cheese also did not correlate with obesity trends. However, our results surprisingly revealed that consumption of com products correlated with rising obesity and was independent of gender and race/ethnicity among population dynamics in the U.S. Therefore, we were able to demonstrate a novel link between the consumption of com products and rising obesity trends that has not been previously attributed to the obesity epidemic. This correlation coincides with the introduction of bioengineered corns into the human food chain, thus raising a new hypothesis that should be tested in molecular and animal models of obesity.

• 한국정보통신학회논문지
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• 제15권4호
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• pp.759-764
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• 2011

본 논문에서는 이동로봇에 장착된 초음파 센서 및 CCD 카메라를 통해 입력되는 환경정보에서 장애물을 인식 및 추출하여 주행전방의 환경을 구분하는 방법을 제시하였다. 복도 내에서 주행하는 로봇에 탑재된 초음파에 입력된 거리 데이터 정보에 의해 장애물을 검출하고 이동로봇이 미지의 동적인 환경을 초음파센서로 인지하여 지능적으로 목표점을 찾아가는 운행 알고리즘을 제안하고 검증하기 위한 실험결과를 제시하였다. 이동로봇에 다양한 센서 기술들을 이용하여 실내에서 활용하기 적합한 지능적 역할을 수행할 수 있는 다목적용 자율 이동 로봇에 환경인식을 위한 pan/tile 카메라(EVI-D30)를 장착하여 주행실험을 할 수 있도록 하였다. 제작한 로봇의 주행성능을 보이기 위해서 VFF 알고리즘을 적용하여 임의의 환경에서도 자율주행의 실험과 결과를 통해 제시한 방법에 대한 유효성을 검증하였다.

• Clinical and Experimental Pediatrics
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• 제49권6호
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• pp.593-601
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• 2006

Allergic rhinitis is a common disease of childhood characterized by nasal, throat, and ocular itching, rhinorrhea, sneezing, nasal congestion. Those affected with allergic rhinitis often suffer from associated inflammatory conditions of the mucosa, such as allergic conjunctivitis, rhinosinusitis, asthma, otitis media with effusion, and other atopic conditions, such as eczema and food allergies. Allergic rhinitis must be diagnosed and treated properly to prevent complications and impaired quality of life. Despite a high prevalence, allergic rhinitis isoften undiagnosed and inadequately treated, especially in the pediatric population. The first step in treatment is environmental control when appropriate. It may be difficult to eliminate all offending allergens effectively to reduce symptoms, so medications are often required. Many different classes of medications are now available, and they have been shown to be effective and safe in a large number of well-designed, clinical trials. Antihistamines are effective in treating immediate symptoms of sneezing, pruritus, watery eyes, and rhinorrhea. Second generation antihistamines are the preferred antihistamines because of their superior side effect profile. Thus, decongestants are commonly used with oral antihistamines. Intranasal corticosteroids are the most effective therapy for allergic rhinitis. Leukotriene modifier may be as effective as antihistamines in treating allergic rhinitis symptoms. Cromolyn sodium is an option for mild disease when used prophylactically, and ipratropium bromide is effective when rhinorrhea is the predominant symptom. When avoidance measures and medications are not effective, specific immunotherapy is an effective alternative. Only immunotherapy results in sustained changes in the immune system. Because of improved understanding of the pathogenesis, new and better therapies may be forthcoming. The effective treatment of allergic rhinitis in children will reduce symptoms and will improve overall health and quality of life, making a happier, healthier child.

• Journal of Plant Biotechnology
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• 제31권3호
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• pp.191-195
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• 2004

복합스트레스 내성 유전자 NDP kinase 2 유전자를 도입시킨 형질전환 감자를 개발하기 위하여 이 유전자를 산화스트레스에 의해 발현이 강하게 유도되는 SWPA2 프로모터 또는 enhanced CaMV 35S 프로모터에 연결한 벡터를 제작한 후 각각 Agrobacterium 매개로 형질전환 하였다. 기관발생 경로에 의해 kanamycin 저항성 식물체를 재분화 시킨 후 Southern 분석으로 외래 유전자가 안정적으로 감자 게놈내로 삽입되었음을 확인하였다. 형질전환 감자 식물체의 잎 조직을 대상으로 10 $\mu$M methyl viologen에 대한 내성 검정을 조사하여 산화스트레스 내성 형질전환 감자 식물체를 2 개체씩 선발하였다. 선발된 식물체는 건조, 고온 등의 여러 가지 환경스트레스 내성 분석을 실시할 예정이며 이로부터 복합재해에 내성을 지닌 감자 품종을 개발할 수 있을 것으로 기대한다.

• 한국산업보건학회지
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• 제23권2호
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• pp.123-136
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• 2013

Objectives: This paper was prepapred to report airborne asbestos fiber concentrations in asbestos textile, brake-lining, commutator, and building materials manufacturing industries, and some other asbestos related industries in Korea from 1994 to 2006. Methods: Airborne asbestos data that have been sampled and analyzed in the above industries during 1994-2006 were collected. These data were reviewed to scrutinize the qualified data based on the records such as sampling and analyzed method and quality control procedures. All asbestos data were generated using the National Institute for Occupational Safety & Health (NIOSH) Method 7400. Results: Average concentration of asbestos fiber was 2.14 fibers/cc(0.02-15.6 fibers/cc) in the asbestos textile industry, 0.26 fibers/cc(0.01-1.01 fibers/cc) in the building-materials industry, 0.15 fibers/cc(0.01-0.93 fibers/cc) in the brake-lining manufacturing industry, and 0.14 fibers/cc(0.03-1.36 fibers/cc) in the commutator producing industry. For these industries, the percentage of samples of which asbestos fiber concentrations above the limit of exposure(0.1 fibers/cc) was 97.6% in the asbestos textile industry, 62.3% in the building-materials industry, 53.5% in the brake-lining manufacturing industry, and 34.3% in the commutator producing industry. Asbestos fiber concentration was below the limit of exposure in the gasket producing, petrochemistry, musical instrument producing industries, and the brake-lining exchange operations. Conclusions: Airborne asbestos fiber level in the asbestos textile, brake-lining producing, commutator and building-material producing industries was above the limit of exposure, but in the gasket producing, petrochemistry, musical instrument producing industries and the brake-lining exchange operations were below the limit of exposure.

• ALGAE
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• 제30권3호
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• pp.217-222
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• 2015

Pythium species (Pythiales, Oomycetes) are well known as the algal pathogen that causes red rot disease in Pyropia / Porphyra species (Bangiales, Rhodophyta). Accurate species identification of the pathogen is important to finding a scientific solution for the disease and to clarify the host-parasite relationship. In Korea, only Pythium porphyrae has been reported from Pyropia species, with identifications based on culture and genetic analysis of the nuclear internal transcribed spacer (ITS) region. Recent fungal DNA barcoding studies have shown the low taxonomic resolution of the ITS region and suggested the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene as an alternative molecular marker to identify Pythium species. In this study, we applied an analysis of both the ITS and cox1 regions to clarify the taxonomic relationships of Korean Pythium species. From the results, the two closely related Pythium species (P. chondricola and P. porphyrae) showed the same ITS sequence, while the cox1 marker successfully discriminated P. chondricola from P. porphyrae. This is the first report of the presence of P. chondricola from the infected blade of Pyropia yezoensis in Asia. This finding of the algal pathogen provides important information for identifying and determining the distribution of Pythium species. Further studies are also needed to confirm whether P. chondricola and P. porphyrae are coexisting as algal pathogens of Pyropia species in Korea.

• Journal of Microbiology and Biotechnology
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• 제19권10호
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• pp.1206-1212
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• 2009

Growth rates, photosystem II photosynthesis, and the levels of chlorophyll $\alpha$ and secondary metabolites of Chlorella ovalis were estimated to determine if they were enhanced by the addition of swine urine (BM) or cow compost water (EP) that had been fermented by soil bacteria to deep seawater (DSW) in an attempt to develop media that enabled batch mass culture at lower costs. Growth of C. ovalis in f/2, f/2-EDTA+BM60%, DSW+BM30%, and DSW+EP60% was enhanced and maintained in the log phase of growth for 16 days. The cell densities of C. ovalis in DSW+EP60% ($4.1{\times}10^6$ Cells/ml) were higher than those of f/2 ($2.9{\times}10^6$ Cells/ml), f/2-E+BM60% ($3.7{\times}10^6$ Cells/ml), and DSW+BM30% ($2.7{\times}10^6$ Cells/ml). The growth rate was also more favorable for C. ovalis cultured in DSW+EP60% ($0.15\;day^{-1}$) than that of C. ovalis cultured in the control medium (f/2) ($0.12\;day^{-1}$). Furthermore, the chlorophyll a concentration of C. ovalis cultured in DSW+EP60% (4.56 mg/l) was more than 2-fold greater than that of C. ovalis cultured in f/2 (2.35 mg/l). Moreover, the maximal quantum yields of photo system II at 470 nm (Fv/Fm) were significantly higher in organisms cultured at f/2-E+BM60% (0.53) and DSW+EP60% (0.52) than in the other treatment groups. Finally, Fourier transformation infrared (FT-IR) spectroscopy revealed that C. ovalis grown in DSW+EP60% had more typical peaks and various biochemical pool shifts than those grown in other types of media. Taken together, the results of this study indicate that the use of DSW+EP60% to culture C. ovalis can reduce maintenance expenses and promote higher yields.

• 센서학회지
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• 제7권5호
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• pp.327-333
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• 1998

본 논문에서는 실내 환경에서의 환경 인자에 대한 사람의 감성을 측정하기 위한 감성 측정기를 개발하였다. 온도, 습도, $CO_2$ 및 $C_4H_{10}$ 농도를 측정할 수 있는 네가지 종류의 센서를 사용하였는데, 감성지수를 정의하기 위해서는 온도, 습도, $CO_2$ 센서만을 사용하였고, $C_4H_{10}$ 센서는 내부 공기의 유해도 측정을 위해 사용하였다. 제안한 측정기는 온도, 습도, $CO_2$ 농도 각각에 대해 따로 감성지수를 설정하고 이를 조합하여 현재 실내환경에 대한 최종 감성지수를 제시하도록 하였다. 제안된 알고리듬의 타당성을 PC 윈도우 95환경에서의 시뮬레이터를 이용하여 확인하였고, 마이크로 프로세서를 사용하여 독립적인 감성측정기를 제작하였다.

• Journal of Microbiology and Biotechnology
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• 제16권7호
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• pp.1032-1040
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• 2006

Some Pseudomonas species can grow on styrene as a sole carbon and energy source. From the new isolate Pseudomonas putida SN1, the genes for styrene catabolism were cloned and sequenced. They were composed of four structural genes for styrene monooxygenase (styA and styB), styrene oxide isomerase (styC), and phenylacetaldehyde dehydrogenase (styD), along with two genes for the regulatory system (styS and styR). All the genes showed high DNA sequence (91% to 99%) and amino acid sequence (94% to 100%) similarities with the corresponding genes of the previously reported styrene-degrading Pseudomonas strains. A recombinant Escherichia coli to contain the styrene monooxygenase from the SN1 was constructed under the control of the T7 promoter for the production of enantiopure (S)-styrene oxide, which is an important chiral building block in organic synthesis. The recombinant E. coli could convert styrene into an enantiopure (S)-styrene oxide (ee >99%) when induced by IPTG The maximum activity was observed as 140 U/g cell, when induced with 1 mM IPTG at $15^{\circ}C$.