• 한국게임학회 논문지
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• 제21권5호
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• pp.115-132
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• 2021

본 연구는 '드래곤 에이지 인퀴지션'의 현지화 사례를 통해 게임 팬 번역가들의 번역 동기 및 번역 활동의 양상에 대해서 고찰하고자 한다. 게임의 상호작용과 경험은 게임 팬 번역을 함에 있어서, 다양한 동기를 부여하고, 번역 활동 역학을 생성한다. 본 연구는 게임 팬 번역가가 생산자와 수용자의 특징을 동시에 보여주는 게임 팬 번역 활동의 과정을 참여관찰하여 확인하고, 게임 팬 번역가들을 심층인터뷰하여 동기를 확인하였다. 이를 통해 게임 팬 번역 활동이 게임팬덤의 생산적 측면을 밝히고, 이후 게임문화에서 팬 번역을 논의해야 할 지점에 대해서 제언해보고자 한다.

• 대한기계학회논문집B
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• 제26권2호
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• pp.362-373
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• 2002

A stereoscopic PIV (SPIV) measurement system based on the translation configuration was developed and applied to the flow behind a forward-swept axial-fan. Measurement of three orthogonal velocity components is essential for flow analysis of three-dimensional flows such as flow around a fan or propeller. In this study, the translation configuration was adopted to calculate the out-of-plane velocity component from 2-D PIV data obtained from two CCD cameras. The error caused by the out-of-plane motion was estimated by direct comparison of the 2-D PIV and 3-D SPIV results that measured from the particle images captured simultaneously. The comparison shows that the error ratio is relatively high in the region of higher out-of-plane motion near the axial fan blade. The turbulence intensity measured by the 2-D PIV method is bigger by about 5.8% in maximum compared with that of the 3-D SPIV method. The phase-averaged velocity field results show that the wake behind an axial fan has a periodic flow structure with respect to the blade phase and the characteristic flow structure is shifted downstream in the next phase.

• ETRI Journal
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• 제32권5호
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• pp.729-739
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• 2010

Due to the rapid development of mobile devices equipped with cameras, instant translation of any text seen in any context is possible. Mobile devices can serve as a translation tool by recognizing the texts presented in the captured scenes. Images captured by cameras will embed more external or unwanted effects which need not to be considered in traditional optical character recognition (OCR). In this paper, we segment a text image captured by mobile devices into individual single characters to facilitate OCR kernel processing. Before proceeding with character segmentation, text detection and text line construction need to be performed in advance. A novel character segmentation method which integrates touched character filters is employed on text images captured by cameras. In addition, periphery features are extracted from the segmented images of touched characters and fed as inputs to support vector machines to calculate the confident values. In our experiment, the accuracy rate of the proposed character segmentation system is 94.90%, which demonstrates the effectiveness of the proposed method.

• Journal of Ginseng Research
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• 제47권3호
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• pp.353-358
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• 2023

Sepsis and septic shock affect millions of people worldwide each year with high clinical mortality rates. At present, basic research on sepsis has emerged in an endless stream, but there are few effective clinical translation results. Ginseng, a medicinal and edible representative of Araliaceae plants, contains a variety of biologically active compounds including ginsenosides, alkaloids, glycosides, polysaccharides, and polypeptides. Neuromodulation, anticancer activity, blood lipid regulation, and antithrombotic activity have been linked to ginseng treatment. At present, basic and clinical research have suggested various applications of ginseng in sepsis. In view of the different effects of various ginseng components on the pathogenesis of sepsis, and in order to further understand and develop the possible value of ginseng in sepsis, this manuscript reviews the application of various components of ginseng in the treatment of sepsis in recent years.

• BMB Reports
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• 제38권2호
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• pp.151-160
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• 2005

By a cDNA array representing 2308 signal transduction related genes, we studied the expression profiles of HeLa cells stably transfected by Hepatitis C virus nonstructural protein 4B (HCV-NS4B). The alterations of the expression of four genes were confirmed by real-time quantitative RT-PCR; and the aldo-keto reductase family 1, member C1 (AKR1C1) enzyme activity was detected in HCV-NS4B transiently transfected HeLa cells and Huh-7, a human hepatoma cell line. Of the 2,308 genes we examined, 34 were up-regulated and 56 were down-regulated. These 90 genes involved oncogenes, tumor suppressors, cell receptors, complements, adhesions, transcription and translation, cytoskeletion and cellular stress. The expression profiling suggested that multiple regulatory pathways were affected by HCV-NS4B directly or indirectly. And since these genes are related to carcinogenesis, host defense system and cell homeostatic mechanism, we can conclude that HCV-NS4B could play some important roles in the pathogenesis mechanism of HCV.

• 한국정보통신학회논문지
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• 제3권1호
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• pp.83-95
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• 1999

웨이브릿 변환은 시간 및 주파수에 대하여 국부성을 가지며, 비정상상태의 신호를 해석하는데 유용하다. 웨이브릿 변환에서의 기저함수들은 원형 웨이브릿을 천이(translation) 및 확장/수축(dilation)을 시킴으로서 만들어진다. 본 논문은 두 개의 웨이브릿을 선형적으로 조합한 선형조합 웨이브릿 변환을 사용하여 시간-주파수 분석방법을 제안하였다. 그리고 제안된 선형조합 웨이브릿 변환을 사용하여 진단모니터링 시스템에 적용하였다. 제안한 선형조합 웨이브릿 변환 분석 방법의 유효성을 검증하기 위하여 FFT(Fast Fourier Transform), Daubechies, Haar 기법과 비교한다. 분석 대상 신호로는 linear chirp 신호, 팬 소음신호, 회전체 회전신호, 전기신호를 사용하였다. 그 결과는 정상상태 신호처럼 비정상상태 시간 신호를 나타내는데 적당하다. 또한 선형조합 웨이브릿을 사용한 진단 모니터링 시스템은 효과적인 신호분석을 수행한다.

• Journal of Microbiology and Biotechnology
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• 제32권3호
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• pp.278-286
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• 2022

Live bacterial vector vaccines are one of the most promising vaccine types and have the advantages of low cost, flexibility, and good safety. Meanwhile, protein secretion systems have been reported as useful tools to facilitate the release of heterologous antigen proteins from bacterial vectors. The twin-arginine translocation (Tat) system is an important protein export system that transports fully folded proteins in a signal peptide-dependent manner. In this study, we constructed a live vector vaccine using an engineered commensal Escherichia coli strain in which amiA and amiC genes were deleted, resulting in a leaky outer membrane that allows the release of periplasmic proteins to the extracellular environment. The protective antigen proteins SLY, enolase, and Sbp against Streptococcus suis were targeted to the Tat pathway by fusing a Tat signal peptide. Our results showed that by exploiting the Tat pathway and the outer membrane-defective E. coli strain, the antigen proteins were successfully secreted. The strains secreting the antigen proteins were used to vaccinate mice. After S. suis challenge, the vaccinated group showed significantly higher survival and milder clinical symptoms compared with the vector group. Further analysis showed that the mice in the vaccinated group had lower burdens of bacteria load and slighter pathological changes. Our study reports a novel live bacterial vector vaccine that uses the Tat system and provides a new alternative for developing S. suis vaccine.

• The Korean Journal of Physiology and Pharmacology
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• 제27권4호
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• pp.345-356
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• 2023

This study aimed to assess the effects of exogenous hydrogen sulfide (H₂S) on abdominal aorta coarctation (AAC) induced myocardial fibrosis (MF) and autophagy in rats. Forty-four Sprague-Dawley rats were randomly divided into control group, AAC group, AAC + H₂S group, and H₂S control group. After a model of rats with AAC was built surgically, AAC + H₂S group and H₂S group were injected intraperitoneally with H₂S (100 µmol/kg) daily. The rats in the control group and the AAC group were injected with the same amount of PBS. We observed that H₂S can improve left ventricular function and the deposition of myocardial collagen fibers, inhibit pyroptosis, down-regulate the expression of P-eif2α in myocardial tissue, and inhibit cell autophagy by activating the phosphatidylinositol 3-kinase (PI3K)/AKT1 signaling pathway (p < 0.05). In addition, angiotensin II (1 µM) H9c2 cardiomyocytes were injured in vitro experiments, and it was also observed that pyroptosis was inhibited after H₂S (400 µmol/kg) intervention, the expression of P-eif2α in cardiomyocytes was significantly down-regulated, and the PI3K/AKT1 signaling pathway was activated at the same time. Therefore, increasing the expression of P-eif2α reverses the activation of the PI3K/AKT1 signaling pathway by H₂S. In conclusion, these findings suggest that exogenous H₂S can ameliorate MF in rats with AAC by inhibiting pyroptosis, and the mechanism may be associated with inhibiting the phosphorylation of eif2α and activating the PI3K/AKT1 signaling pathway to inhibit excessive cell autophagy.

• 비교문화연구
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• 제40권
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• pp.213-238
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• 2015

본 논문은 "한한대사전"에 기재된 "사기 열전" 관련 어휘 가운데 드러나 보이는 5가지의 문제를 규정(옳게 바꿈)한 것이다. 필자는 크게 의미해석 오류수정, 의미해석 보충수정으로 나누어 설명하였다. 그 대강의 내용은 아래와 같다. 첫째, 의미해석 오류수정에서는 "가여", "교칙", "관채"의 풀이가 "한한대사전"에서 잘못 기재되어있음을 밝혔다. 독자로 하여금 혼돈을 일으키기 쉬운 그럴듯한 해석으로 본의를 상실한 한 경우가 대부분이었다. 각각은 "빌려 줌${\rightarrow}$주다", "정리함${\rightarrow}$옛 것을 제거하고 새롭게 꾸밈, 수식, 교정윤식(색)", "관찰하여 채택함. 살펴서 취함${\rightarrow}$(주의 깊게) 찾아보다, 물색하다"로 의미해석을 수정해 주어야 한다. 둘째, 의미해석 보충수정에서는 "효실", "심념"의 의미항목이 부족함을 언급하였다. 각각에 대하여 "실력을 드러내다", "깊은 시름에 잠기다"의 풀이를 보충해 주었다. 또한 국내외 학자들의 번역본을 비교해보면 다음과 같은 결론을 얻을 수 있다. "가여" 항목은 정범진의 풀이가 가장 정확했다. "교칙" 항목은 박일봉, 왕리기, 양종현 학지달의 풀이가 비교적 타당했다. "관채"항목은 박일봉과 왕리기의 번역이 적합했다. "효실" 항목에서는 김원중이 올바른 해석을 했으며, "심념" 항목은 왕중의 번역이 가장 이상적이라고 사료된다.