• Gut and Liver
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• v.12 no.6
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• pp.694-703
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• 2018

Background/Aims: Limited data exist comparing the safety and efficacy of direct-acting antivirals (DAAs) in hepatitis C virus (HCV) monoinfected and HCV/human immunodeficiency virus (HIV) coinfected patients in the real-world clinic practice setting. Methods: All HCV monoinfected and HCV/HIV coinfected patients treated with DAAs between January 2014 and October 2017 in community clinic settings were retrospectively analyzed. Pretreatment baseline patient characteristics, treatment efficacy, factors affecting sustained virologic response at 12 weeks (SVR12) after treatment, and adverse reactions were compared between the groups. Results: A total of 327 patients were included in the study, of which 253 were HCV monoinfected, and 74 were HCV/HIV coinfected. There was a statistically significant difference observed in SVR12 when comparing HCV monoinfection and HCV/HIV coinfection (94% and 84%, respectively, p=0.005). However, there were no significant factors identified as a predictor of a reduced response. The most common adverse effect was fatigue (27%). No significant drug interaction was observed between DAA and antiretroviral therapy. None of the patients discontinued the treatment due to adverse events. Conclusions: In a real-world setting, DAA regimens have lower SVR12 in HCV/HIV coinfection than in HCV monoinfection. Further studies involving a higher number of HCV/HIV coinfected patients are needed to identify real predictors of a reduced response.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.10
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• pp.296-302
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• 2019

In this study, a basic durability assessment was performed by selecting the main part of a trial product of a shale shaker, which is one of components for a mud circular system. For a preliminary durability assessment, it was assumed that the lifetime of the bearing for the vibrator motor and the stiffness of the support spring are affected by the vibration when the motor operates continuously. In the case of the motor, the initial p-p level was 0.72 g, but after 100 hours of operation, the p-p level was rapidly increased to 1.26 g. Bearing defects could be estimated through ball defect frequency analysis. In the case of the spring, the stiffness of the spring was reduced by approximately 3.78% at the end of 2,000 hours of the fatigue-durability test by applying excitation conditions to shale shaker body. In the future, we will analyze the influence of the particle removal efficiency of the shale shaker.

• The Journal of Internal Korean Medicine
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• v.40 no.5
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• pp.797-803
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• 2019

Introduction: The aim of this study was to report the effect of Korean medicine treatments on a stroke patient with homonymous hemianopsia. Case Presentation: A 50-year-old male with a posterior cerebral artery infarction had continuously deteriorating symptoms of right homonymous hemianopsia, fatigue, dizziness, and light sensitivity. Treatment with Korean medicine therapy, including acupuncture and herbal medicine significantly improved the patient's symptoms. The result of a visual field test (VFI) was also improved after treatment, and no side effects were observed during treatment. Conclusion: Korean medicine treatment can be considered an effective treatment for homonymous hemianopsia in stroke patients.

• Journal of the Microelectronics and Packaging Society
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• v.26 no.3
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• pp.63-69
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• 2019

Soldering technology has been used in electronic industry for a long time. However, due to solder fatigue characteristics, automotive electronics are searching the semi-permanent interconnection technology such as press-fit method. Press fit interconnection is a joining technology that mechanically inserts a press fit metal terminal into a through hole in a board, and induces a strong bonding by closely contacting the inner surface joining of the through hole by plastic deformation of press-fit terminal. In this paper, the bonding properties of press-fit interconnection are investigated with PCB hole size and surface finishes. In order to compare interconnection reliability between the press fit and soldering, the change in resistance of the press-fit and soldering joints was observed during thermal shock test. After thermal cycling, the failure modes are investigated to reveal the degradation mechanism both press-fit and soldering technology.

• Journal of the Korean Society of Propulsion Engineers
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• v.14 no.4
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• pp.39-45
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• 2010

Thick-walled cylinders, such as a cannon or nuclear reactor, are autofrettaged to induce advantageous residual stresses into pressure vessels and to increase operating pressure and the fatigue lifetimes. As the autofrettage level increases, the magnitude of compressive residual stress at the bore also increases. The purpose of the present paper is to predict the accurate residual stress of SCM440 high strength steel using the Kendall model which was adopted by ASME Code. Hydraulic pressure process was applied in the inner part and thick-walled cylinders were autofrettaged up to 30% overstrain levels. Electro polishing on the surface of autofrettage specimen was performed to get more accurate residual stress. Residual stresses were measured by X-ray diffraction method. The autofrettage surface which was plastically deformed analyzed using a scanning electron microscope(SEM). Although there were some differences in measured residual stress and numerical results, it has a tendency to agree comparatively with each other.

• Journal of the Korean Society of Propulsion Engineers
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• v.21 no.1
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• pp.26-35
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• 2017

The high-cycle fatigue cracking and the resonance generated in operation of a centrifugal compressor are main cause of the impeller damage. In order to prevent the damage, the impeller is designed or modified to have sufficient strength to withstand the operating condition. The damage prevent design will lead to a change of the flow condition and the performance characteristics of the compressor. In this study, the computational analysis were performed to identify the flow and the performance characteristics. The cases are a scalloped and a increased the blade thickness models with a closed type impeller. As the analysis results, the value of head coefficient and total to total efficiency for the increased the blade thickness model was decreased by each 0.5% and 0.1% than the values of the baseline model. Each value for the scalloped model was increased by 0.4% and was decreased by 1.6%.

• Journal of the Korean Society of Propulsion Engineers
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• v.22 no.4
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• pp.24-35
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• 2018

Impeller blades in the centrifugal compressor are subjected to periodic aerodynamic excitations by interactions between the impeller and the diffuser vanes (DV) in resonant conditions. This may cause high cycle fatigue (HCF) and eventually result in failure of the blades. In order to predict the structural response accurately, the aerodynamic excitation and the major resonant conditions were predicted using unsteady computational fluid dynamics (CFD) and structural analysis. Then, a forced vibration analysis was performed by going through one-way fluid-structure interaction (FSI). A numerical analysis procedure was established to evaluate the structural safety with respect to HCF. The numerical analysis procedure proposed in this paper is expected to contribute toward preventing HCF problems in the initial design stage of an impeller.

• Steel and Composite Structures
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• v.21 no.6
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• pp.1227-1250
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• 2016

Most of the research work has been conducted on K-joints under static loading. Very limited information is available in consideration of fatigue strength of K-joints with concrete-filled chord. This paper aims to describe experimental and numerical investigations on stress concentration factors (SCFs) of concrete-filled circular chord and square braces K-joints under balanced axial loading. Experiment was conducted to study the hot spot stress distribution along the intersection of chord and braces in the two specimens with compacting concrete filled in the chord. The test results of stress distribution curves of two specimens were reported. SCFs of concrete-filled circular chord and square braces K-joints were lower than those of corresponding hollow circular chord and square brace K-joints. The corresponding finite element analysis was also conducted to simulate stress distribution along the brace and chord intersection region of joints. It was achieved that experimental and finite element analysis results had good agreement. Therefore, an extensive parametric study was carried out by using the calibrated finite element model to evaluate the effects of main geometric parameters and concrete strength on the behavior of concrete-filled circular chord and square braces K-joints under balanced axial loading. The SCFs at the hot spot locations obtained from ABAQUS were compared with those calculated by using design formula given in the CIDECT for hollow SHS-SHS K-joints. CIDECT Design Guide was generally quite conservative for predicting SCFs of braces and was dangerous for predicting SCFs of chord in concrete-filled circular chord and square braces K-joints. Finally SCF formulae were proposed for circular chord and square braces K-joints with concrete-filled in the chord under balanced axial loading. It is shown that the SCFs calculated from the proposed design equation are generally in agreement with the values derived from finite element analysis, which were proved to be reliable and accurate.

• Journal of the Korea Society for Simulation
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• v.27 no.1
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• pp.119-126
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• 2018

This study intended to exploratively testify human error causing factors for railway traffic controller, using AMOS structural equation model. Through literature survey, fatigue and stress as exogenous variable, errors in information process such as cognitive, memory, storage, and execution error as endogenous variable, and accident and incident(near-miss) as dependent variable were set up. Results based on AMOS using 201 railway traffic controllers' questionnaire showed that a clear causality loop like as 'stress ${\rightarrow}$ memory error ${\rightarrow}$ storage error ${\rightarrow}$ incident(near-miss) ${\rightarrow}$ accident' is formed. This result suggests that for the purpose of mitigation of traffic controller's accident, it is so necessary to reduce memory and execution error in the information processing process based on the effective management of stress, as the precedent of them.

• Journal of the Korea Safety Management & Science
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• v.17 no.3
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• pp.115-123
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• 2015

The study conducted statistical analysis of survey on the 239 workers participating in national Tower Crane installation/dismantlement in order to identify work environment and health hazard exposure of Tower Crane workers. Consequently for work related safety status of Tower Crane workers, the number of installation/dismantlement work was the highest at 15-20 times per month, and safety equipments were not arranged at work and they felt highly anxious when boarding on the Tower Crane. Furthermore, it is found that they feel anxious working in the influence of the weather, noise, vibration, wind, the sun ray, and structure characteristic. They have very low satisfaction in the insecureness of workplace and the work environment, and recognizes that their work affect highly on the health. 81.6% of workers have experienced accident at work, the cause of accidents were mainly due to poor work environment, and the health abnormality they have experienced were mostly fatigue and concentration reduction. For job stress, job demand and conflict in relationship were the highest sections. Total 66.5% of workers complained of musculoskeletal disorder related subjective symptom, and back pain patients were the highest of all groups.