• Molecules and Cells
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• v.23 no.3
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• pp.316-322
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• 2007

Zinc finger transcription factor genes are a significant fraction of the genes in the vertebrate genome. Here we report the isolation and characterization of a human zinc finger-containing gene, ZNF435, from a fetal brain cDNA library. ZNF435 cDNA is 1290 base pairs in length and contains an open reading frame encoding 349 amino acids with four C2H2-type zinc fingers at its carboxyl terminus and a SCAN motif at its amino terminus. RT-PCR results showed that ZNF435 was expressed in all tested tissues. A ZNF435-GFP fusion protein was located in the nucleus and the four zinc fingers acted as nuclear localization signals (NLSs). ZNF435 was found to be capable of homo-association, and this effect was independent of its zinc fingers. Furthermore, ZNF435 proved to be a transcription repressor as its overexpression in AD293 cells inhibited the transcriptional activities of AP-1.

• Journal of the Ergonomics Society of Korea
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• v.26 no.2
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• pp.149-155
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• 2007

Recently, various devices requiring text input such as mobile phone IPTV, PDA and UMPC are emerging. The frequency of text entry for them is also increasing. This study was focused on the evaluation of Korean text entry interface. Various models to evaluate text entry interfaces have been proposed. Most of models were based on human cognitive process for text input. The cognitive process was divided into two components; visual scanning process and finger movement process. The time spent for visual scanning process was modeled as Hick-Hyman law, while the time for finger movement was determined as Fitts' law. There are three questions on the model-based evaluation of text entry interface. Firstly, are human cognitive processes (visual scanning and finger movement) during the entry of text sequentially occurring as the models. Secondly, is it possible to predict real text input time by previous models. Thirdly, does the human cognitive process for text input vary according to users' text entry speed. There was time gap between the real measured text input time and predicted time. The time gap was larger in the case of participants with high speed to enter text. The reason was found out investigating Eye-Hand Coordination during text input process. Differently from an assumption that visual scan on the keyboard is followed by a finger movement, the experienced group performed both visual scanning and finger movement simultaneously. Arrival Lead Time was investigated to measure the extent of time overlapping between two processes. 'Arrival Lead Time' is the interval between the eye fixation on the target button and the button click. In addition to the arrival lead time, it was revealed that the experienced group uses the less number of fixations during text entry than the novice group. This result will contribute to the improvement of evaluation model for text entry interface.

• Restorative Dentistry and Endodontics
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• v.29 no.3
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• pp.226-232
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• 2004

Use of electric pulp testing elicits painful response in vital teeth. In this study, we examined the excessive time from pain feeling to stimulation disconnection in clinical situation. D626D (Parkell Inc., USA.) scan type electric pulp tester was used in total of 23 young healthy individuals. Each of the right central incisors and first premolars were used as testing teeth. Stimulation disconnection was achieved by EMG in anterior belly of digastric muscle, finger span, and voice and the excessive stimulation time over the sensory thresh-old was recorded. As a result, we found that the short responses before the stimulation disconnection appeared following order：EMG, finger span, and voice. The EMG disconnection is suggested to be used to reduce the excessive stimulus time in electric pulp testing.

• Biomedical Science Letters
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• v.28 no.1
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• pp.9-24
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• 2022

The aim of this study was to identify the expression of zinc finger E-box binding homeobox 1 (ZEB1), its prognostic significance, and correlation between ZEB1 and infiltrating immune cells in lung cancer. Correlation between ZEB1 and telomerase was also analyzed in different types of cancers. RNA sequencing analysis and survival rates of patients were confirmed by Gene Expression Profiling Interactive Analysis (GEPIA). The Kaplan-Meier plotter and PrognoScan databases were used to analyze the prognostic value of ZEB1 in various cancers. The Tumor IMmune Estimation Resource (TIMER) was used to determine the correlation between ZEB1 and infiltrating immune cells. Lower ZEB1 expression was lower in lung cancer and was related to poor prognosis in lung adenocarcinoma (LUAD). ZEB1 expression exhibited a significantly positive correlation with infiltration levels of immune cells in LUAD and lung squamous cell carcinoma. Furthermore, we found that the ZEB1 expression correlated with subunits of telomerase. Our findings suggest ZEB1 as a potential biomarker to be used for prognostic significance and tumor immunology in lung cancer. The correlation between the expression of ZEB1 and telomere-related gene will help in understand the cancer-promoting mechanisms.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.1
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• pp.824-827
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• 2005

The need to be able to identify other individual human beings is fundamental to the security and has been true since the beginning of human history. Physical or behavioral characteristics (finger-scan, face-scan, voice, palm, iris, retina, signature, human DNA, keystroke, vain, gait etc.) of a person are used to authenticate the person. The biometric technologies allow for a greater reliability of authentication as compared with password systems for physical access, network security, e-commerce, and so on. In this paper, we describe various technologies, market analysis, multi-modal system, standardization, privacy issue and future prospect of biometrics.

• The Journal of Internal Korean Medicine
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• v.22 no.2
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• pp.257-262
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• 2001

Cheiro-oral syndrome is characterized by a partial sensory disturbance in one hand and the ipsilateral oral comer. Its lesion is on the sensory track, and it is comparatively small. Most studies are case studies. These studies reported less than 10 cases. We studied two cases. In one, we observed intracranial hemorrhage involving left thalamus, posterior limb of internal capsule about 5cc in brain computed tomographic scan. The case was shown paresthesia of the right hand and ipsilateral comer of the mouth. The patient also complained about disturbing dysstereognosis and disorder of graphaesthesia. In the other case, we observed nodular calcification at the left basal ganglia external capsule in brain computed tomographic scan. The patient also complained about dysesthesia of the right thumb and index finger, fatigue and verbal disturbance. These cases appeared to be typical strokes in the acute phase, but after acute phase, they had dysethesia in the hand and periord for three months.

• Interaction and multiscale mechanics
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• v.3 no.2
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• pp.173-191
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• 2010

Damage detection plays a very important role to the maintenance of bridge structures. Traditional damage detection methods are usually based on structural dynamic properties, which are acquired from pre-installed sensors on the bridge. This is not only time-consuming and costly, but also suffers from poor sensitivity to damage if only natural frequencies and mode shapes are concerned in a noisy environment. Recently, the idea of using the dynamic responses of a passing vehicle shows a convenient and economical way for damage detection of bridge structures. Inspired by this new idea and the well-established tap test in the field of non-destructive testing, this paper proposes a new method for obtaining the damage information through the acceleration of a passing vehicle enhanced by a tapping device. Since no finger-print is required of the intact structure, this method can be easily implemented in practice. The logistics of this method is illustrated by a vehicle-bridge interaction model, along with the sensitivity analysis presented in detail. The validity of the method is proved by some numerical examples, and remarks are given concerning the potential implementation of the method as well as the directions for future research.

• The Journal of the Korea Contents Association
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• v.17 no.9
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• pp.132-144
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• 2017

The fingerprint classification of categorizing fingerprints by classes should be used in order to improve the processing speed and accuracy in a fingerprint recognition system using a large database. The fingerprint classification methods extract features from the fingerprint ridges of a fingerprint and classify the fingerprint using learning and reasoning techniques based on the classes defined according to the flow and shape of the fingerprint ridges. In earlier days, many researches have been conducted using NIST database acquired by pressing or rolling finger against a paper. However, as automated systems using live-scan scanners for fingerprint recognition have become popular, researches using fingerprint images obtained by live-scan scanners, such as fingerprint data provided by FVC, are increasing. And these days the methods of fingerprint classification using Deep Learning have proposed. In this paper, we investigate the trends of fingerprint classification technology and compare the classification performance of the technology. We desire to assist fingerprint classification research with increasing large fingerprint database in improving the performance by mentioning the necessity of fingerprint classification research with consideration for fingerprint images based on live-scan scanners and analyzing fingerprint classification using deep learning.

• Proceedings of the Korean Society of Computer Information Conference
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• 2016.07a
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• pp.243-244
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• 2016

은행거래를 하려면 Active X를 기반으로 하는 보안 통합설치프로그램, 공인인증 보안프로그램, 개인 PC방화벽 프로그램 등 보안에 필요한 프로그램을 설치해야한다. 그러나 Active X의 보안취약점으로 앞으로 나올 브라우저에서는 Active X대신 웹 표준 모듈을 기반으로 하는 보안 시스템을 제공하고 있다. 본 논문은 Active X를 대체할 수 있는 것으로 웹 표준 모델에 근거한 QR코드 및 지문인식을 통한 인증을 제안한다. 본 논문에서 제안한 시스템을 적용한다면, 보다 안전한 은행거래를 하는데 도움을 줄 수 있다.

• Applied Chemistry for Engineering
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• v.3 no.3
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• pp.516-521
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• 1992

Hydroxypropyl chitin (HPCH) was prepared by reacting chitin with propylene oxide. HPCH showed the improved solubility in several organic solvents compared with chitin. It showed the remarkable solubility in formic acid. Form the results of polarized microscopic observatoin of HPCH solution in formic acid, finger-print pattern was observed in concentrations over 30 wt% solution. Since no typical thermogram was observed in DSC scan, the HPCH showed a lyotropic cholestric liquid crystallinity.