• Korean Journal of Optics and Photonics
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• v.15 no.5
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• pp.429-434
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• 2004

An ophthalmic endoscope which is used in medical applications should have the total diameter less than 1 mm. Its image resolution is limited to 30∼40 lp/mm. Therefore, the image resolution is one of the most important factors to decide image quality of the ophthalmic endoscopic images. This study obtained high resolution and magnifying ophthalmic endoscopic images by a new optical design using a 0.23 pitch GRIN lens and high resolution fiber-optic image guide which has less than 5 ${\mu}{\textrm}{m}$ diameter microfibers. The resolutions of images from existing and from a new type of ophthalmic endoscope are measured and compared using a USAF resolution target.

• Korean Journal of Veterinary Service
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• v.36 no.2
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• pp.73-78
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• 2013

This study was conducted to investigate antibiotic resistance among Salmonella Typhimurium isolates from diseased pigs in Gyeongbuk province during the period 1998~2011. One hundred forty one isolates were tested for antibiotic resistance using the standard disk diffusion method and were examined for presence of resistance gene by PCR method. S. Typhimurium showed high drug resistance rates to tetracycline (95.7%), streptomycin (93.6%), ampicillin (86.5%), cephalothin (80.1%), gentamicin (79.4%), and trimethoprim/sulfamethoxazole (72.3%). Resistance gene, blaTEM, blaPSE1, tetA, tetB, tetG, sul1, sul2, aadA, strA, grm, and temA were detected among the antibiotic resistance isolates and temB, tetC, aadB gene were not detected. One hundred twenty one (89.6%) tetA, two (1.5%) tetB and one (0.7%) tetG gene were detected in the 135 tetracycline resistant isolates. Two (1.6%) temA gene were detected in one hundred twenty two ampicillin resistance isolates and temB was not detected.

• Journal of the Korea Convergence Society
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• v.8 no.6
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• pp.1-7
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• 2017

This study examined how the memory effect and the brand attitude effect differ according to the interaction (high / low) and the involvement (high / low) of digital signage. The two-way MANOVA analysis using SPSS 18 was used for the empirical analysis. The results of this study are as follows: First, GRM is recalled if the level of interactivity and inffence of digital signage is low, but if both conditions are high, ARM recalls. Second, if the interaction of digital signage is low and the level of engagement is high, a lot of memory information is formed that forms the overall attitude of the product. In addition, even though the interaction level is high and the engagement is low, the attitude cognitive response through the overall evaluation is formed rather than the attribute information. Third, brand attitude was positive when interactivity level was high and engagement level was high.

• Journal of the Korean Recycled Construction Resources Institute
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• v.9 no.4
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• pp.425-432
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• 2021

In this paper, We produced supporting for ginseng cultivation facilities as a material recycling product of CPW(Complex Plastic Wastes, CPW) from households. And we analyzed the characteristics of material recycling products according to the amount of r-LDPE(Recycled low density polyethylene, r-LDPE) used. As a result, as the amount of recycled LDPE used increa sed, the tensile strength a nd elonga tion of ma teria l recycled products using CPW increa sed, but a sh decrea sed. When the recycled r-LDPE usage is 5% or more, the physical properties of the material recycling product using CPW stably satisfy the quality standard (GRM 3093-2021) of supporting for ginseng cultivation facilities.

• Journal of Ginseng Research
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• v.43 no.4
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• pp.625-634
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• 2019

Background: Ginsenoside Rg3, a derivative of steroidal saponins abundant in ginseng, has a range of effects on cancer cells, including anti-cell proliferation and anti-inflammation activity. Here, we investigate two long noncoding RNAs (lncRNAs), STXBP5-AS1 and RFX3-AS1, which are hypomethylated and hypermethylated in the promoter region by Rg3 in MCF-7 cancer cells. Methods: The lncRNAs epigenetically regulated by Rg3 were mined using methylation array analysis. The effect of the lncRNAs on the apoptosis and proliferation of MCF-7 cells was monitored in the presence of Rg3 or Korean Red Ginseng (KRG) extract after deregulating the lncRNAs. The expression of the lncRNAs and their target genes was examined using qPCR and Western blot analysis. The association between the expression of the target genes and the survival rate of breast cancer patients was analyzed using the Kaplan-Meier Plotter platform. Results: STXBP5-AS1 and RFX3-AS1 exhibited anti- and pro-proliferation effects, respectively, in the cancer cells, and the effects of Rg3 and KRG extract on apoptosis and cell proliferation were weakened after deregulating the lncRNAs. Of the genes located close to STXBP5-AS1 and RFX3-AS1 on the chromosome, STXBP5, GRM1, RFX3, and SLC1A1 were regulated by the lncRNAs on the RNA and protein level. Breast cancer patients that exhibited a higher expression of the target genes of the lncRNAs had a higher metastasis-free survival rate. Conclusion: The current study is the first to identify lncRNAs that are regulated by the presence of Rg3 and KRG extract and that subsequently contribute to inhibiting the proliferation of cancer cells.

• Resources Recycling
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• v.30 no.4
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• pp.20-26
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• 2021

Solar grade silicon (SoG-Si) has been commercially supplied mainly from off-grade high-purity silicon manufactured for electronic-grade Si (EG-Si). Therefore, for wider application of solar cells, the development of a refining process at a considerably lower cost is required. The most cost-effective and direct approach for producing SoG-Si is to purify and upgrade metallurgical-grade Si (MG-Si). In this study, directional solidification of molten MG-Si was conducted in a high-frequency induction furnace to remove iron from molten Si. The experimental conditions and results were also discussed with respect to the effective segregation coefficient, Scheil equation, and Peclet number. The study showed that when the descent velocity of the specimen decreased, the macro segregations of impurities and ingot purities increased. These results were derived from the decrease in the effective segregation coefficient with the decrease in the rate of descent of the specimen.

• Korean Journal of Agricultural Science
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• v.49 no.3
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• pp.431-440
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• 2022

Hanwoo cattle are a unique and historical breed in Korea that have been genetically improved and maintained by the national evaluation and selection system. The aim of this study was to provide information that can help improve the accuracy of the estimated breeding values in Hanwoo cattle by showing the difference between the imputation reference chip platforms of genomic data and the scaling factor of the genetic relationship matrix (GRM). In this study, nine sets of data were compared that consisted of 3 reference platforms each with 3 different scaling factors (-0.5, 0 and 0.5). The evaluation was performed using MTG2.0 with nine different GRMs for the same number of genotyped animals, pedigree, and phenotype data. A five multi-trait model was used for the evaluation in this study which is the same model used in the national evaluation system. Our results show that the Hanwoo custom v1 platform is the best option for all traits, providing a mean accuracy improvement by 0.1 - 0.3%. In the case of the scaling factor, regardless of the imputation chip platform, a setting of -1 resulted in a better accuracy increased by 0.5 to 1.6% compared to the other scaling factors. In conclusion, this study revealed that Hanwoo custom v1 used as the imputation reference chip platform and a scaling factor of -0.5 can improve the accuracy of the estimated breeding value in the Hanwoo population. This information could help to improve the current evaluation system.

• Korean Journal of Agricultural Science
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• v.48 no.4
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• pp.681-691
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• 2021

The estimated breeding value (EBV) and accuracy of Hanwoo steer (Korean cattle) is an indicator that can predict the slaughter time in the future and carcass performance outcomes. Recently, studies using pedigrees and genotypes are being actively conducted to improve the accuracy of the EBV. In this study, the pedigree and genotype of 46 steers obtained from livestock farm A in Gyeongnam were used for a pedigree best linear unbiased prediction (PBLUP) and a genomic best linear unbiased prediction (GBLUP) to estimate and analyze the breeding value and accuracy of the carcass weight (CWT), eye muscle area (EMA), back-fat thickness (BFT), and marbling score (MS). PBLUP estimated the EBV and accuracy by constructing a numeric relationship matrix (NRM) from the 46 steers and reference population I (545,483 heads) with the pedigree and phenotype. GBLUP estimated genomic EBV (GEBV) and accuracy by constructing a genomic relationship matrix (GRM) from the 46 steers and reference population II (16,972 heads) with the genotype and phenotype. As a result, in the order of CWT, EMA, BFT, and MS, the accuracy levels of PBLUP were 0.531, 0.519, 0.524 and 0.530, while the accuracy outcomes of GBLUP were 0.799, 0.779, 0.768, and 0.810. The accuracy estimated by GBLUP was 50.1 - 53.1% higher than that estimated by PBLUP. GEBV estimated with the genotype is expected to show higher accuracy than the EBV calculated using only the pedigree and is thus expected to be used as basic data for genomic selection in the future.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.266-266
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• 2020

본 연구에서는 기후변화로 인한 남북공유하천유역의 미래 수문특성 변화를 전망하기 위해 ArcGIS 프로그램을 통해 산정된 격자형 수문특성 매개변수를 분포형 모형인 GRM에 적용하여 임진강유역의 미래 유출수문특성 변화를 분석하였다. 분포형 모형에 사용되는 강우량 자료는 기상관측소 단위로 상세화된 13개 전지구 기후 모델 중 RCP4.5, 8.5 시나리오의 공유하천유역 인접 11개 관측소별 빈도해석 결과를 시·공간적으로 분포하여 사용하였다. 또한 미래기간별 유출특성 변화추이를 분석하기 위하여 참조기간(1981-2005), 21세기 전반기(F1, 2011-2040), 중반기(F2, 2041-2070), 후반기(F3, 2071-2100)로 구분하여 분석을 실시하였다. 분석 결과 본 연구의 대상지점인 임진강유역은 기후변화로 인해 확률강우량이 증가하여 유역의 유출수문특성에 직접적인 영향이 있을 것으로 예측되었다. RCP 4.5 시나리오에서는 21세기 후반기인 F3에 확률강우량 및 유출량의 증가추세가 줄어들 것으로 전망되나, 참조기간 대비 F1에서 20.4%, F2에서 35.7%, F3에서 34.6%의 평균 유출량 증가율을 보였으며, RCP 8.5 시나리오에서는 F1에서 19.9%, F2에서 38.3%, F3에서 67.8%로 지속적인 증가가 전망되었다. 또한 첨두홍수량 발생시각은 참조기간 대비 약 4.6~13.3% 감소가 예상되었다. 기후변화로 인한 홍수량의 변화는 재해위험을 증가시킬 수 있으며, 이러한 상황에서 남한과 북한의 협력을 통한 유역통합관리의 필요성은 점차 커질 것으로 보인다. 이를 위해서는 정확한 수문학적 분석을 선행하여야 하며, 본 연구가 남북공유하천유역의 재해위험을 평가하는 기초자료로 활용될 수 있을 것으로 판단된다.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.402-402
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• 2021

다목적댐의 유입량은 댐 저수지 관리 및 운영에 있어 중요한 고려사항으로, 정확한 유입량을 사용하는 것이 필수적이다. 댐 저수지 유입량은 유역의 물수지분석, 홍수조절 의사결정 등 이·치수적 측면에서 활용도가 높으며, 특히 기후변화로 인한 홍수나 가뭄의 발생이 빈번해진 최근의 상황에서 위기경보 운영 등 재난관리 측면에서도 그 중요성이 높아지고 있다. 현재 우리나라에서는 댐 저수지 유입량 산정에 방류량과 저수지 수위를 활용한 물수지방정식에 의한 방법을 공식적으로 활용하고 있다. 그러나 물수지방정식을 이용하여 계산된 유입량은 평수기와 갈수기 오차가 크고 음의 유입량 값이 발생하는 등 지속적인 개선의 필요성이 제기되었다. 이를 보완하기 위해 댐 저수지 직상류부 하천의 수위 측정치로부터 수위-유량곡선을 통해 유량을 산출하고, 그 값을 활용하여 댐 방류량을 추정하는 방법이 제시되었다. 그러나 직상류부 수위 측정이 불가능한 저수지에는 활용이 어렵기 때문에 다양한 지점에 적용할 수 없다는 한계가 있다. 본 연구에서는 기존 댐 저수지 유입량 산정방식의 한계를 보완하기 위해 수위계측이 어려운 지점에서도 유량 계산이 가능한 분포형 강우-유출모형 GRM(Grid based Rainfall-runoff model)을 연구에 활용하였다. 한강권역 내 K-water 운영 다목적댐인 소양강댐, 횡성댐, 충주댐 직상류부 유량과 분포형 강우-유출모형으로 계산된 유량을 비교하여 모의 유량자료의 활용성을 검토하였다. 다음으로 댐 유입지점-상류 관측지점 간 유량의 상관관계를 분석하였으며, 이를 통해 상류 하천에 흐르는 유량으로부터 댐 유입량을 계산할 수 있는 관계곡선식을 도출하였다. 본 연구에서 제시한 댐 유입량 산정방식은 관측지점의 다양성과 결과의 정확도를 향상시킬 수 있다는 측면에서 기존 방식 개선에 활용할 수 있을 것으로 기대된다. 또한 분석 절차의 표준화나 결과에 대한 다양한 검증이 이루어진다면, 홍수 및 가뭄의 위기경보 발령에 대한 참고자료로 활용이 가능할 것으로 판단된다.