• Title, Summary, Keyword: GV20

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The Effects of Acupuncture at the GV20 and GV22 on the Electroencephalogram(EEG) (백회(百會)(GV20).신회(顖會)(GV22) 자침이 뇌파에 미치는 영향)

  • Lee, Sang-Hun;Ryu, Yeon-Hee;Kwon, O-Sang;Sohn, In-Chul
    • Korean Journal of Acupuncture
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    • v.29 no.3
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    • pp.467-475
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    • 2012
  • Objectives : The aim of this study was to examine the effects of Acupuncture at the GV20 and GV22 on normal human beings using power spectrum analysis. Methods : Electroencephalogram(EEG) power spectrum exhibits site-specific and state-related differences in various frequency bands. 8 channels Background Electroencephalogram (EEG) was carried out in 30 subjects(24 females and 4 males). Results : In ${\delta}$(theta) band, the power values decreased significantly at the 8-channel average value(p=0.03) and especially at T3(p=0.02), T4(p=0.001) and P3(p=0.03). In ${\alpha}$(alpha) band, the power values have no significant changes. In ${\beta}$(beta)band, the power values increased significantly at the 8-channel average value (p=0.02) and especially at T4(p=0.003), P3 (p= 0.03) and P4(0.02). In ${\beta}/{\delta}$(beta/theta) ratio, the value increased significantly at the 8-channel average value(p=0.002) and especially at Fp2(p=0.05), F4(p=0.007), T3(0.012), T4(0.005), P3 (0.007) and P4(0.03) Conclusions : Through this data, we conclude that acupuncture at the GV20 and GV22 on normal human beings could have possibility to awake the cerebral cortex by the functional mechanism.

Effects of Ramulus Uncariae Cum Uncis' Herbal Acupuncture on Transient Forebrain Ischemic Injury in Rats (흰쥐의 일과성 전뇌 허혈 손상에 대한 조구등 약침의 효과)

  • 고정수;김재효;최동옥;김경식;손인철
    • The Journal of Korean Medicine
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    • v.24 no.2
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    • pp.66-80
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    • 2003
  • Objectives : Recently, herbal acupuncture has been developed in the Korea since the earlier 1960' applied to various diseases including the cerebrovascular accident. The main characteristics of herbal acupuncture are a combination the merit of acupuncture and herbal medicine. It was not well known the therapeutic effect and the mechanism of herbal acupuncture on transient forebrain ischemic injury, although it has been used frequently in clinics. Ramulus Uncariae Cum Uncis (釣鉤藤) has been claimed to possess sedative, anti-spasmodic actions, and treat childhood epilepsy in oriental medical preparation. Also, it has been stated that Ramulus Uncariae Cum Uncis was antioxidatvie effect and neuroprotection against glutamateinduced neuronal death. Methods : In this study, effects of Ramulus Uncariae Cum Uncis' herbal acupuncture on the $GV_{20}{\;}or{\;}LR_3$, named Baek-hue or Tae-chung, on neuroprotection after the transient forebrain ischemia were investigated in Sprague-Dawely rats. Expressions of cFos, FosB and BDNF protein in the hippocampus and cortex were observed at 2 hrs and 48 hrs after transient forebrain ischemia by immunohistochemistry and ELISA technique. Results : Expression of cFos protein was increased slightly in the hippocampus and cortex at 2 hrs after transient forebrain ischemia, but FosB protein was increased highly comparing to cFos protein. However, pretreatment with Ramulus Uncariae Cum Uncis' herbal acupuncture on $GV_{20}{\;}or{\;}LR_3$ significantly increased expression of cFos protein and significantly decreased expression of FosB protein compared to control group, respectively. These features were observed in the motor cortex and retrosplenial granular cortex as well as the hippocampus. Especially, cFos expression was more increased at the herbal acupuncture on $GV_{20}{\;}than{\;}LR_3$, but FosB expression was more decreased in $LR_3$ group than $GV_{20}$ group. Also, pretreatment with Ramulus Uncariae Cum Uncis' herbal acupuncture on $GV_{20}{\;}or{\;}LR_3$ significantly increased the expression of BDNF protein in the hippocampus ($254.88{\pm}12{\;}pg/ml{\;}in{\;}GV_{20}$ group, $245.93{\pm}44.4{\;}pg/ml{\;}in{\;}LR_3$ group) and the cortex ($85.81{\pm}3.45{\;}pg/ml{\;}in{\;}GV_{20}$ group, $111.51{\pm}15.79{\;}pg/ml{\;}in{\;}LR_3$, group) compared to the hippocampus ($134.07{\pm}2.96{\;}pg/ml$) and the cortex ($61.16{\pm}4.11{\;}pg/ml$) in control group at 48 hrs after transient forebrain ischemia. Conclusion : These results suggest that pretreatment with Ramulus Uncariae Cum Uncis' herbal acupuncture on $GV_{20}{\;}or{\;}LR_3$ has neuroprotective effect on transient forebrain ischemia and the herbal acupunture on $GV_{20}{\;}or{\;}LR_3$ may be related to antioxidative effect and calcium channel block of Ramulus Uncariae Cum Uncis. Also, it could be mentioned there is specificity of acupoints treating ischemic injury through the difference between the herbal acupuncture of $GV_{20}{\;}and{\;}LR_3$.

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Effects of Acupuncture at GV 20(Baihui) Evaluated by the Second Derivative of Photoplethysmogram Waveform under Stress (백회혈(百會穴) 자침(刺鍼)이 스트레스 상태에서의 가속도맥파에 미치는 영향)

  • Lee, Jin-Hwan;Kim, Jin-Yi;Kim, Soo-Jung;Seo, Joo-Hee;Sung, Woo-Yong
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.3
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    • pp.19-27
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    • 2010
  • Objectives : This study was designed to report the effect of acupuncture at GV 20(Baihui) evaluated by the second derivative of photoplethysmogram waveform(SDPTG) under stress. Methods : 15 healthy volunteers participated in this study. 1. After 5 minutes rest, mental stress was provided for 5 minutes. And then subjects rested for 15 minutes. SDPTG was recorded before and after mental stress and after 15 minutes restness. 2. After 5 minutes rest, mental stress was provided for 5 minutes. And acupuncture at GV 20 remained for 15 minutes. SDPTG was recorded before and after mental stress and after 15 minutes acupuncture. Results : 1. Mental Stress didn't make significant change at SDPTG. 2. In a comparison of pre-acupuncture and post-acupuncture at the GV 20, b/a ratio(P<0.05) and Sano aging index(P<0.05) was decreased significantly. Conclusions : We concluded that acupuncture at the GV 20 may be effective method to recover vascular function.

Effect of Simple Acupuncture and Electroacupuncture at Bai Hui($GV_{20}$) on Heart Rate Variability in Healthy Adults with Stress Task (백회(百會)($GV_{20}$) 단순 자침과 전침 자극이 정신적 스트레스를 가한 정상 성인의 심박변이도에 미치는 영향 비교)

  • Kim, Ji-Na;Lee, Ji-Su;Hong, Jung-Soo;Kim, Soo-Jung;Moon, Sung-Il
    • Journal of Acupuncture Research
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    • v.29 no.3
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    • pp.89-99
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    • 2012
  • Objectives : This study was performed to investigate the effect of simple acupuncture and electroacupuncture at Bai Hui($GV_{20}$) on heart rate variability in healthy adults with stress task. Methods : 40 healthy volunteers participated in this study. HRV was recorded before and after stress. And then simple acupuncture(SA group) was applied at $GV_{20}$ or electroacupuncture(EA group) was applied at the same spot in each treatment group for 20 minutes. No treatment was performed in control group for 20 minutes. Then HRV was recorded. Results : 1. In all groups, LF norm, LF/HF, HF norm showed significant changes after mental stress. 2. Control group showed no significant change. In SA group, HF norm LF, LF norm and LF/HF showed a significant change after treatment. In EA group, Mean HR, HF, LF norm, HF norm and LF/HF showed a significant change after treatment. In both treatment groups, there were significant differences after treatment compared to control group. 3. In EA group, HF and HF norm decreased significantly after treatment compared to SA group. Conclusions : These results suggest that simple acupuncture and electroacupuncture at $GV_{20}$ affect the balance of the autonomic nervous system and that electroacupuncture at $GV_{20}$ enhances parasympathetic activation more than simple acupuncture.

A study on acupoints and muscles used for cosmetic acupuncture (미용침(cosmetic acupuncture)에 응용되는 경혈과 근육에 대한 고찰)

  • Yang, Mi-Sung;Shin, Mi-Sook
    • Korean Journal of Acupuncture
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    • v.26 no.3
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    • pp.13-25
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    • 2009
  • Objectives : This study was performed to investigate acupoints and muscles used for cosmetic acupuncture. We want most clinicians practicing cosmetic acupuncture to understand theoretical background well and to treat cosmetic diseases more diversely by this paper. Methods : We collected useful informations from some books and websites about cosmetic acupuncture and thus could select major acupoints and muscles. Conculsions : The most frequently used acupoints for cosmetic acupoints are as follows ; LI20, ST1, ST2, ST3, ST4, ST5, ST6, ST7, ST8, SI18, SI19, BL1, BL2, BL3, BL4, TE17, TE18, TE19, TE20, TE21, TE22, TE23, GB1, GB2, GB3, GB4, GB5, GB6, GB7, GB8, GB13, GB14, GV20, GV21, GV22, GV23, GV24, GV25, GV26 and CV24. And head and neck muscles including SCM muscle, plastyma, frontalis, corrugator supercilii, orbicularis oculi, auricularis, temporalis, masseter, pterygoid, zygomaticus and risorius can be used for cosmetic acupuncture. Most acupoints and muscles are located in face and head, which seemed to be concerned with formation of face wrinkles.

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Laser Acupuncture at GV20 Improves Brain Damage and Oxidative Stress in Animal Model of Focal Ischemic Stroke

  • Jittiwat, Jinatta
    • Journal of Acupuncture & Meridian Studies
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    • v.10 no.5
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    • pp.324-330
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    • 2017
  • The burden of stroke is high and is continually increasing due to a dramatic growth in the world's elderly population. Novel therapeutic strategies are therefore required. The present study sought to determine the effect of laser acupuncture at GV20 on brain damage, oxidative-status markers in the cerebral cortex, and superoxide dismutase in the mitochondria of an animal model of focal ischemic stroke. Wistar rats, weighing 300-350 g, were divided into the following four groups: (1) control; (2) permanent occlusion of the right middle cerebral artery (Rt.MCAO) alone; (3) Rt.MCAO plus sham laser acupuncture; and (4) Rt.MCAO plus laser-acupuncture groups. Sham laser acupuncture or laser acupuncture was performed once daily at the GV20 (Baihui) acupoint for 14 days following Rt.MCAO. Half of the rats in each group were examined by 2,3,5-triphenyltetrazolium chloride staining to determine the brain infarct volume, while the other half were examined by biochemical assays to determine the malondialdehyde level, and the glutathione peroxidase, catalase, and superoxide-dismutase activities in the brain-cortex mitochondria. The results showed that laser acupuncture at GV20 significantly decreased the brain infarct volume and malondialdehyde level, and increased the catalase, glutathione peroxidase, and superoxide-dismutase activities in cerebral ischemic rats. In conclusion, laser acupuncture at GV20 decreases the brain infarct volume in cerebral ischemic rats, at least in part due to decreased oxidative stress. Further study is warranted to investigate other possible underlying mechanisms.

Adenosine Modulate the Oocyte Developmental Competence by Exposing Stages and Synthetic Blocking during In Vitro Maturation

  • Cheon, Yong-Pil
    • Development and Reproduction
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    • v.20 no.2
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    • pp.127-133
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    • 2016
  • Purine metabolism is known factor for nuclear maturation of oocytes through both follicle cells and oocyte itself. However, it is largely unknown the roles of purine metabolism in the oocyte competence for fertilization and early development. In this study, the effects of adenosine in oocyte competence for development were examined using adenosine and its synthetic inhibitors. Adenosine treatment from GV intact stage for 18 hr (fGV) caused of decrease the fertilization rate but of increase the cleavage rate compared from the other stage treatment groups. Hadacidin did not effect on fertilization rate but increased cleavage rate without stage specificity. Adenosine did not block the effects of hadacidin with the exception of fGV group. Inhibition of purine synthetic pathways the fertilization rate was decreased in the fGV and fGVB groups but increased in the fMII group. Exogenous adenosine caused of decrease fertilization rate in the fGVB group but increase in the fMII group. Cleavage rate was dramatically increased in the adenosine treatment with synthetic inhibitors. It means that the metabolism of purine has stage specific effects on fertilization and cleavage. Exogenous adenosine had only can improve oocyte developmental competence when it treated at GV intact stage. On the other hand, endogenous synthesis in all maturation stage cause of increase the cleavage rate without effects on fertilization. These data suggest that adenosine at GV stage as a paracrine fashion and inhibitions of endogenous adenosine in all stage improve oocyte developmental competence.

Studies on Agronomical Characteristics of Rice Varieties Recommended during 1910-1980 in Korea (수도 품종변천에 따른 유용형질의 특성변이에 관한 연구)

  • ;Eun-Woong Lee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.28 no.1
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    • pp.12-40
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    • 1983
  • Heading behaviour of native japonica (GI) and Japanese varieties (GII) grown during 1910-1920s were thermo-sensitive, home bred varieties during 1930s (GIII) - 1950s (GIV) were photo-sensitive and semi-dwarf indica derived varieties released since 1971 (GV) were controlled by basic vegetative phase. Number of leaves on main culm was increased with varietal improvement and culm length was gradually shortened as variety improved. GV variety had the shortest plant height among the groups. The first internode length was about 30cm in all groups and difference of 2nd-4th internode length was caused shortening the culm length. Panicle length and diameter of panicle neck were shortened and became thinner as variety developed from GI to GIV, however, GV had longer panicle and thick panicle neck, respectively. Number of panicles/hill and straw weight/hill increased and became heavier as variety improve from GI to GIV but GV had moderate number of panicle/hill and relatively light straw weight. Number of spikelet/panicle has been reduced with varietal improvement but GV had the biggest number. Grain yield/hill also increased as variety improved, however, it was decreased as transplanting season postponed and GV had shown the most sensitive difference. Top dry matter weight at heading stage and at 20 days after heading (20 DAH) had no difference among the groups except GI which was the smallest. Average grain weight at 20 DAH was heavier in the order of GI > GII, GV > GIV > GIII. It had a little variation in GI & GII while that of other variety group showed significant decrease as transplanting delayed. Harvest index (HI) of GV was the highest at 54% for the earlier transplanting and GIII had the lowest HI. Difference of HI became conspicuous for the later transplanting, the varieties bred later had the lower HI when transplanting of rice delayed. At the earliest transplanting applied (May 15), the grain yield was higher in the order of GI > GIV > GIII > GII > GI, however, that of Tongil type variety (GV) was the lowest for the latest transplanting (June 29). Interrelationship among the agronomical characteristics and grain yield was discussed.

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Effects of Electroacupuncture at Some Acupoints on the Cardiovascular System in Dogs Anesthetized with Tiletamine/zolazepam (Tiletamine/zolazepam 마취견에서 전침자극이 순환기계에 미치는 영향)

  • 강한샘;장환수;이문학;엄기동;장광호
    • Journal of Veterinary Clinics
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    • v.20 no.2
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    • pp.224-228
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    • 2003
  • This study was performed to evaluate the effect of electroacupuncture at some acupoint combinations on the cardiovascular system, especially on blood pressure. Electroacupuncture at acupoint combinations of CV2O(+)/GV-16(-),4(+)/GV16(-), KI1(+)/GV20(-), and HT9(+)/GV16(-) did not changed heart rates and blood pressure, but stimulation of HT1(+)/HT7(-) Increased systolic, diastolic and mean arterial blood pressure significantly in dogs anesthetized with tiletamine/zolazepam.

Differentially Expressed mRNA Profiles between Immature Germinal Vesicle(GV) and Mature Metaphase II(MII) Mouse Oocytes (미성숙 난자와 성숙 난자에서 서로 다르게 발현하는 유전자에 관한 연구)

  • Yoon Se-Jin;Chung Hyung-Min;Cha Kwang-Yul;Kim Nam-Hyung;Lee Kyung-Ah
    • Development and Reproduction
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    • v.8 no.1
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    • pp.35-42
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    • 2004
  • Oocyte maturation refers to the process that prophase I arrested germinal vesicle(GV) drives the progression of meiosis to metaphase II(MII) to have the capacity for fertilization and embryo development. To better understand the molecular mechanism(s) involved in oocyte maturation, we identified differentially expressed genes(DEGs) between GV and MII mouse oocytes using a new innovative annealing control primer (ACP) technology. Using 20 ACPs, we successfully cloned 32 DEGs between GV and Mll oocytes, and 26 out of these 32 DEGs were functionally known genes. Four genes including Pscd2 were GV-specific, 10 genes including PKD2 and CSN3 were highly expressed in GV oocytes(GV-selective), and 12 genes including Diva were highly expressed in MII oocytes (MII-selective). Ail of the genes identified in this study were first reported in the oocyte expression using ACP system and especially, we could characterize the existence of PKD-CSW signaling pathwayin the mouse oocytes. Results of the present study would provide insight for studying molecular mechanisms regulating oocyte maturation.

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