• Title/Summary/Keyword: Gain score analysis

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A Study of Choice for Analysis Method on Repeated Measures Clinical Data

  • Song, Jung
    • Korean Journal of Clinical Laboratory Science
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    • v.45 no.2
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    • pp.60-65
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    • 2013
  • Data from repeated measurements are accomplished through repeatedly processing the same subject under different conditions and different points of view. The power of testing enhances the choice of pertinent analysis methods that agrees with the characteristics of data concerned and the situation involved. Along with the clinical example, this paper compares the analysis of the variance on ex-post tests, gain score analysis, analysis by mixed design and analysis of covariance employable for repeating measure. Comparing the analysis of variance on ex post test, and gain score analysis on correlations, leads to the fact that the latter enhances the power of the test and diminishes the variance of error terms. The concluded probability, identified that the gain score analysis and the mixed design on interaction between "between subjects factor" and "within subjects factor", are identical. The analysis of covariance, demonstrated better power of the test and smaller error terms than the gain score analysis. Research on four analysis method found that the analysis of covariance is the most appropriate in clinical data than two repeated test with high correlation and ex ante affects ex post.

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Linkage Mapping and QTL on Chromosome 6 in Hanwoo (Korean Cattle)

  • Kim, J.W.;Park, S.I.;Yeo, J.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.10
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    • pp.1402-1405
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    • 2003
  • The QTL(quantitative traits loci) linkage mapping of Hanwoo (Korean Cattle) chromosome 6 for daily gain and marbling score was performed using 378 individuals from 18 paternal half-sib families in Hanwoo. Hanwoo chromosome 6 were mapped to total length of 394.2 cM between 28 microsatellite loci using 36 microsatellite primers of BTA 6 linkage group. The QTL analysis for daily gain in Hanwoo showed 8 microsatellite loci (BM3026-5.66, EL03-5.58, BM4311-5.29, ILSTS035-4.50, BMS1242-4.37, BM1329-3.67, BM415-3.11, BMS2460-3.03) in larger than LOD score 3.0. Based on the QTL analysis for marbling score, LOD scores of 12 microsatellite loci (BM415-8.88, BM3026-7.15, ILSTS093-5.45, ILSTS035-4.91, EL03-4.69, BMS690-4.52, BM1329-4.43, BMS511-3.74, BMS1242-3.66, BMS518-3.65, BM4311-3.41, BMC4203-3.36) were found larger than 3.0.

Development and Application of Tutorial for Conceptual Change on Object Recognition of Scientific Gifted in Elementary School (초등과학 영재의 물체 인식 개념 변화를 위한 튜토리얼의 개발과 적용)

  • Lee, Ji-Won;Kim, Jung-Bok
    • Journal of Korean Elementary Science Education
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    • v.30 no.3
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    • pp.340-352
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    • 2011
  • The purpose of this study was to analyze effects of teaching materials for elementary science gifted conception about object recognition. Elementary science gifted have misconceptions that they can see in lightness. They can not explain how a shadow is made. This paper reports in-depth investigation on elementary science gifted's understanding of object recognition focusing on process of light. A program is developed to elementary science gifted in the subject matter. The tutorial emphasizing the process of light consists of pre-test, worksheet, and post-test. The Tutorial has 4 steps; darkness and light, light on things, light reached eyes, structure of the eyes. Each steps has 2~4 experiments. Through the tutorial, we expect their misconceptions can be changed into scientific conceptions. For the research and analysis, a questionnaire is posed to 39 elementary science gifted at M Elementary School in D Metropolitan City. The first method of product analysis makes a comparative study of pre-test, post-test score, and hake gain each test. As a result, total score of all student was raised. And hake gain of pre-test(II) is 0.6, hake gain of post-test is 0.68. It is Medium gain. Also, elementary science gifted could understand how we see through the tutorial emphasizing process of light. And their misconceptions can be changed into scientific conceptions.

Identification of Superior Single Nucleotide Polymorphisms (SNP) Combinations Related to Economic Traits by Genotype Matrix Mapping (GMM) in Hanwoo (Korean Cattle)

  • Lee, Yoon-Seok;Oh, Dong-Yep;Lee, Yong-Won;Yeo, Jung-Sou;Lee, Jea-Young
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.11
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    • pp.1504-1513
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    • 2011
  • It is important to identify genetic interactions related to human diseases or animal traits. Many linear statistical models have been reported but they did not consider genetic interactions. Genotype matrix mapping (GMM) has been developed to identify genetic interactions. This study uses the GMM method to detect superior SNP combinations of the CCDC158 gene that influences average daily gain, marbling score, cold carcass weight and longissimus muscle dorsi area traits in Hanwoo. We evaluated the statistical significance of the major SNP combinations selected by implementing the permutation test of the F-measure. The effect of g.34425+102 A>T (AA), g.8778G>A (GG) and g.4102+36T>G (GT) SNP combinations produced higher performance of average daily gain, marbling score, cold carcass weight and the longissimus muscle dorsi area traits than the effect of a single SNP. GMM is a fast and reliable method for multiple SNP analysis with potential application in marker-assisted selection. GMM may prospectively be used for genetic assessment of quantitative traits after further development.

Correlates of the Pregnancy Experience and Attitude regarding Weight Change during Pregnancy in Primigravida Women (초임부의 임신경험과 임신 중 체중변화에 대한 태도와의 관계)

  • Shin, Gisoo;Kim, Miok
    • Korean Journal of Women Health Nursing
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    • v.25 no.2
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    • pp.143-153
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    • 2019
  • Purpose: We aimed to examine the correlations between pregnancy experience and attitude regarding weight change during pregnancy. Methods: This correlative study was conducted from July 2017 to October 2017 by involving 156 primigravida women who were over pregnancy 20 weeks in Seoul and Gyeonggi-do province. Data were collected using a questionnaire, which included questions on demographic data, experience during pregnancy, and attitude regarding weight change during pregnancy. Descriptive statistics were calculated. Also, independent t-test, ANOVA, and Pearson's correlation coefficients were used for data analysis. Results: The mean age of the participants was 30.62 years and their score of attitude regarding weight gain during pregnancy was low. Moreover, a significant correlation was found between the pregnancy experience and attitude regarding weight gain during pregnancy in primigravida women. Conclusion: As a result of analyzing the correlation between pregnancy experience and attitude towards weight gain during pregnancy, it is apparent that attitudes toward weight change are different according to experience during pregnancy in women. Based on these results, it can be concluded that nursing intervention programs are necessitated to enhance the attitude of pregnant primigravida women towards pregnancy and weight gain.

Effects of Simulation-based Practice Education for Core Skill of Maternity Nursing (분만간호 핵심술기에 대한 시뮬레이션 실습교육의 효과)

  • Song, Young A;Son, Young Ju
    • Korean Parent-Child Health Journal
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    • v.16 no.1
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    • pp.37-44
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    • 2013
  • Purpose: The purpose of this study is to analyze the effectiveness of maternity nursing education-knowledge, skills and attitude among the third year students who have completed maternity nursing, practice at the college, clinical practice and core skill practicum. Methods: This is the descriptive research to verify the effectiveness of simulation-based practice education for core skill of maternity nursing. Third year nursing students who have completed maternity nursing related theories and practice have been selected as population. Total of 202 surveys have been used for analysis. Data analysis is done by using SPSS/WIN 18.0. Results: Self-confidence of core skill in maternity nursing is experimental group 4.52 and control group 4.37 score (p<.05). Performance competence in childbirth care is experimental group 4.53 and control group 4.35 score (p<.05). The students who have maternity nursing related clinical practice and core skill practicum experience show high core skill evaluation score. Conclusion: Therefore, it is recommended that current maternity nursing core skill curriculum should be reviewed and improved, and the students should be provided variety of simulation techniques to gain essential knowledge and core nursing skills.

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The Analysis of Achieved Score earned by LEED Healthcare (LEED Healthcare에서 득점 현황 분석에 관한 연구)

  • Kang, Jeeeun
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.25 no.3
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    • pp.7-14
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    • 2019
  • Purpose: The purpose of this research is to find out week and strong aspects in LEED categories based on achieved scores earned by LEED-HC(Healthcare) v.2009. Methods: The LEED-HC scorecards of 88 healthcare projects are analyzed. The analysis are focused on relationship between achieved scores, LEED categories and achieved levels. This relationship was presented by graphs and charts. Results: 1) Compare to LEED-NC, in LEED-HC, sub-categories related to public health are added. The scores are added in Energy Atmosphere and Indoor Environmental Quality. 2) Achieve scores in Sustainable Site are high and one in Energy Atmosphere and Indoor Environmental Quality are low at all levels. 3) Scores which was lost in Energy Atmosphere are recovered in Material Resource and Sustainable Site in order to keep its level. 4) Since most of scores in Energy Atmosphere are under EAc1 Optimize energy performance sub-categories, it is important to achieve more score in Optimize Energy Performance Sub-Categories to gain a higher level. Even if LEED-HC has more score in Energy Atmosphere, this is a hard to achieve scores in that categories. It is important to review Energy Atmosphere categories and its points for improvement. Implications: This study will provide basic database in order to establish Korean green building rating system for hospital.

An application of datamining approach to CQI using the discharge summary (퇴원요약 데이터베이스를 이용한 데이터마이닝 기법의 CQI 활동에의 황용 방안)

  • 선미옥;채영문;이해종;이선희;강성홍;호승희
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2000.11a
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    • pp.289-299
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    • 2000
  • This study provides an application of datamining approach to CQI(Continuous Quality Improvement) using the discharge summary. First, we found a process variation in hospital infection rate by SPC (Statistical Process Control) technique. Second, importance of factors influencing hospital infection was inferred through the decision tree analysis which is a classification method in data-mining approach. The most important factor was surgery followed by comorbidity and length of operation. Comorbidity was further divided into age and principal diagnosis and the length of operation was further divided into age and chief complaint. 24 rules of hospital infection were generated by the decision tree analysis. Of these, 9 rules with predictive prover greater than 50% were suggested as guidelines for hospital infection control. The optimum range of target group in hospital infection control were Identified through the information gain summary. Association rule, which is another kind of datamining method, was performed to analyze the relationship between principal diagnosis and comorbidity. The confidence score, which measures the decree of association, between urinary tract infection and causal bacillus was the highest, followed by the score between postoperative wound disruption find postoperative wound infection. This study demonstrated how datamining approach could be used to provide information to support prospective surveillance of hospital infection. The datamining technique can also be applied to various areas fur CQI using other hospital databases.

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Difference of Functional Outcome and Related Factors in Patients With Stroke (일부 뇌졸중 환자의 기능변화 및 관련요인)

  • Yi, Seung-Ju;Jeong, Seong-Yeong
    • Physical Therapy Korea
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    • v.14 no.1
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    • pp.46-54
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    • 2007
  • The purposes of the present study were to determine the difference of functional outcome, and to identify factors associated with functional difference in patients with stroke. The sample consisted of 56 stroke patients who had received physical therapy at the physical therapy unit of the Dongeui Medical Center in Busan city between January 2000 and June 2002. Stroke patients were evaluated by physical therapists 3 times; The first day in physical therapy (PT) (T1), one month after the first day in PT (T2), and two months after the first day in PT (T3). Functional status was assessed with the Functional Independence Measure (FIM) instrument, a validated instrument for documenting the severity of disability and assessing the outcome of rehabilitation treatment. Functional gain was calculated over T2-T1, T3-T1, and T3-T2. SAS statistical software was used for the analysis. The Student's t-test, paired t-test, analysis of variance (ANOVA/Tukey and Scheffe), and analysis of covariance (ANCOVA) were used to examine the functional difference in variables. Repeated measures ANOVA was also used to analyze the functional difference by time (T1, T2, and T3). Multiple regression analysis was performed to determine the effects of independent variables on the difference of functional outcome as defined by the FIM score. A total of 56 stroke patients were evaluated, their average age${\pm}$standard deviation was $61.6{\pm}9.3$ years (range: 40~81 yr). The functional status of patients who received physical therapy for about 2~3 months was significantly improved (mean FIM scores, $20.5{\pm}1.8$, $28.9{\pm}1.9$, and $8.41{\pm}1.1$ points for each time period, respectively) (p<.0001). Diabetes was significantly associated with the FIM score for T2-T1 (p<.05). The type of diagnosis was significantly associated with the FIM score for T3-T1 (p<.05). Gender, smoking, and the FIM score on admission were significantly associated with the FIM score for T3-T2 (p<.05). In conclusion, gender, smoking, diabetes, the type of diagnosis, and the FIM score on admission were significantly associated with improved FIM scores. We recommend that further research should explore the functional outcome by using larger sample sizes, longer follow-up periods, and more sensitive assessment instruments.

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Changes of Appetite and Eating Behavior in Bipolar Disorder Patients : Measurement with General-Food Craving Questionnaire-Trait and the Drug-Related Eating Behavior Questionnaire (양극성 장애 환자에서 나타나는 식욕 및 섭식 행동의 특성 : 일반적 음식갈망-특질척도(G-FCQ-T)와 약물 관련 섭식행동 설문지(DR-EBQ)를 이용한 평가)

  • Lee, Sunny;Ryu, Seung-Hyong;Ko, Hyo-Jung;Hong, Kyung-Sue;Nam, Hee-Jung
    • Korean Journal of Biological Psychiatry
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    • v.18 no.4
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    • pp.245-253
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    • 2011
  • Objectives In the current study, we quantitatively estimated changes in appetite and eating behavior of bipolar disorder patients during the pharmacotherapy. We also investigated their contribution to the weight gain and their association with specific food-craving characteristics of the patients. Methods Subjects included forty-one bipolar disorder patients and fifty-six controls. Currently sustained natures of food craving were assessed using the General-Food Craving Questionnaire-Trait (G-FCQ-T) and changes in appetite and eating behavior were measured using the Drug-Related Eating Behavior Questionnaire (DR-EBQ). Results Compared to the control group, the patients' group showed significantly higher body mass index (t=2.028, p=0.045). The patients' group had significantly higher 'Preoccupation with food' factor score of G-FCQ-T (p=0.016) than that of the control group. Hierarchical multiple regression analysis showed that only 'preoccupation with food' factor independently predicted psychotropic medication-induced appetite change. Conclusions Appetite change while receiving psychotropic medication seems to be related to the weight-gain and associated with craving natures of 'preoccupation with food' in bipolar disorder. Appetite and/or eating behavioral changes measured by G-FCQ-T and DR-EBQ could be regarded as an important mediating factor in future studies exploring biological mechanisms of weight gain related with pharmacotherapy for bipolar disorder.