• Title, Summary, Keyword: Gyejigabuja-tang

Search Result 4, Processing Time 0.039 seconds

Study of the Effects of Gyejigabuja-tang on Liver Function in Patients with Musculoskeletal Disease (계지가부자탕이 근골격계 질환을 주소로 내원한 환자들의 간 기능에 미치는 영향)

  • Chae, Han-nah;Lee, Jun-young;Shim, Sang-song;Shin, Sun-ho;Shin, Yong-jeen
    • The Journal of Internal Korean Medicine
    • /
    • v.40 no.6
    • /
    • pp.1043-1050
    • /
    • 2019
  • Objectives: This study aimed to investigate the effects of Gyejigabuja-tang on liver function in patients with musculoskeletal disease. Methods: This research compared and analyzed data from liver function tests on patients who were treated with Gyejigabuja-tang during 17.98±1.78 days. Results: No significant effects appeared in the liver function of patients who were treated with Gyejigabuja-tang. Conclusions: This study suggests that Gyejigabuja-tang, which includes Aconiti Radix Lateralis Preparata, known as a toxic herb, may be used without causing significant liver injury if administered correctly as in this study.

A case report of urinary incontinence improved by Gyejigabuja-tang. (계지가부자탕(桂枝加附子湯)을 이용하여 호전된 요실금 치험 1례)

  • Yun, Hyo-Joong;Lee, Soong-In
    • Herbal Formula Science
    • /
    • v.26 no.4
    • /
    • pp.381-389
    • /
    • 2018
  • Objective : The purpose of this case report is to offer an unprecedented target for Gyejigabuja-tang by analyzing a case in which the symptoms were improved by the herbal decoction therapy, and to accumulate a fundamental knowledge in herbal medicine therapy for urinary incontinence. Method : We studied a patient's chart with the patient's consent and displayed patient's timeline and adherence in a figure according to the CARE guideline. The progress of urination symptoms were assessed with the frequency of urination and how long the patient can stand urine. The accompanied lower limb pain was estimated with Numerical Rating Scale(NRS) Results : The patient's adherence was good during the medication period and symptoms related with urination and accompanied lower limb pain were improved with no specific side effects. NRS of the lower limb pain decreased from 7 to 2, the frequency of urination also improved from over 10 times to 6~8 times per day, and the patient can stand urine from less than 1 second to 2~3 minutes. Conclusions : Gyejigabuja-tang was effective for an urinary incontinence patient which corresponds to the provision No.20 in Shanghanlun.

A Case Study with Gyejigabuja-tang on the Menopausal Female Patient who Complained of Excessive Sweating After Bilateral Salpingo-oophorectomy (양측난소절제술 후 발생한 한출과다(汗出過多)를 주소로 하는 갱년기증후군 환자에 대한 계지가부자탕(桂枝加附子湯) 치험 1례)

  • Kim, Jin-Woo;Park, Kang-In;Park, Kyoung-Sun;Lee, Jin-Moo
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.26 no.4
    • /
    • pp.213-222
    • /
    • 2013
  • Purpose: The purpose of this study is to evaluate the effects of Gyejigabuja-tang on a menopausal female patient complained of excessive sweating after bilateral salpingo-oophorectomy (BSO). Methods: We studied one menopausal female patient complained of excessive sweating who visited OO University Hospital from 10th July 2013 to 23th July 2013. We only treated her with Gyejigabuja-tang. The climacteric symptoms of the patient had been estimated with Numeric Rating Scale (NRS) and Menopause Rating Scale (MRS). Results: After treatment, climacteric symptoms were improved and the score of MRS was reduced from 20 to 10 during 12days. NRS score of sweating was reduced from 10 to 2. NRS scores of fatigue, hot flush, thirst, anorexia, dyspepsia, back pain and cramp of calves also reduced after treatment. Conclusions: This study suggests that Gyejigabuja-tang significantly reduced the climacteric symptoms of patient.

Effects of Gyejigabuja-tang on MIA-induced Osteoarthritis in Rats (계지가부자탕(桂枝加附子湯)이 MIA로 유도된 골관절염 Rat 모델에 미치는 영향)

  • Won, Je-Hoon;Woo, Chang-Hoon
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.25 no.2
    • /
    • pp.51-64
    • /
    • 2015
  • Objectives This study was carried out to investigate the effects of Gyejigabuja-tang extracts on the Monosodium iodoacetate (MIA) induced osteoarthritis in rats. Methods Osteoarthritis was induced by injection of MIA into knee joint cavity of rats. Rats are divided into 4 groups (normal, control, positive comparison group, GBT group, each n=5). Normal group was injected by normal saline into knee joint cavity only. Control group was induced for osteoarthritis by MIA and oral medicated with distilled water. Positive comparison group was injected with MIA and taken Joins tablet 25 mg/kg. GBT group was injected with MIA and taken Gyejigabuja-tang extracts 300 mg/kg. Positive comparison group and GBT group were oral medicated for each substance once a day for 4 weeks. ALT, AST and creatinine were evaluated for hepatotoxicity and nephrotoxicity. Hind paw weight bearing ability was examined and inflammatory cytokines (IL-$1{\beta}$, IL-6, TNF-${\alpha}$), $PGE_2$, $LTB_4$, osteocalcin and deoxypyridinoline (DPD) within serum were analysed. Knee joint structures were observed by Hematoxylin & Eosin (H&E), Safranin-O staining method. Results 1. Function of liver and kidney was not affected. 2. Hind paw weight bearing ability was significantly improved. 3. IL-$1{\beta}$, IL-6 and TNF-${\alpha}$ in experimental group were significantly decreased compared with control group. 4. $PGE_2$, $LTB_4$, Osteocalcin and DPD in experimental group were decreased compared with control group. 5. In histopathologic observation, injury on synovial membrane and cartilage of experimental group was lesser than control group (H&E, Safranin-O staining). Conclusions Based on these results, it can be suggested that Gyejigabuja-tang has anti-inflammation effects on the MIA-induced osteoarthritis in rats.