• Title/Summary/Keyword: HRR

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Roles of Budding Yeast Hrr25 in Recombination and Sporulation

  • Lee, Min-Su;Joo, Jeong Hwan;Kim, Keunpil
    • Journal of Microbiology and Biotechnology
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    • v.27 no.6
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    • pp.1198-1203
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    • 2017
  • Hrr25, a casein kinase $1{\delta}/{\varepsilon}$ homolog in budding yeast, is essential to set up mono-orientation of sister kinetochores during meiosis. Hrr25 kinase activity coordinates sister chromatid cohesion via cohesin phosphorylation. Here, we investigated the prophase role of Hrr25 using the auxin-inducible degron system and by ectopic expression of Hrr25 during yeast meiosis. Hrr25 mediates nuclear division in meiosis I but does not affect DNA replication. We also found that initiation of meiotic double-strand breaks as well as joint molecule formation were normal in HRR25-deficient cells. Thus, Hrr25 is essential for termination of meiotic division but not homologous recombination.

Evaluation of the Prediction of B-RISK-FDS-Coupled Simulations for Multi-Combustible Fire Behavior in a Compartment (구획실 내 가연물들의 화재거동에 대한 B-RISK와 FDS 연계 화재 시뮬레이션 예측성능 평가)

  • Baek, Bitna;Oh, Chang Bo
    • Fire Science and Engineering
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    • v.33 no.4
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    • pp.50-58
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    • 2019
  • The prediction performance of B-RISK was evaluated for the fire behaviors of combustibles in a compartment using Fire Dynamics Simulator (FDS). First of all, to predict the heat release rate (HRR) for two combustible sets, the HRR for one combustible set and the design fire curve were used as input values for B-RISK. Comparing results of B-RISK calculations with experimental data for two combustible sets, it was found that B-RISK results predicted insufficiently for fire growth rate of experimental data but there was good agreement for maximum HRR and total HRR with the experimental data. And the B-RISK results were used for input values of FDS to evaluate the fire behaviors of B-RISK results. Comparing results of FDS calculations with experimental data, the simulation results showed that the temperature and concentrations of O2, CO2 in the fire growth phase were different from the experimental data. However, when using the B-RISK result for percentile 70%, the simulation results sufficiently predicted the overall fire behaviors.

An Analysis of False Alarm Threshold Value by Heat Detector Using Heat Release Rate (열방출률을 이용한 열감지기의 오동작 경계값 분석)

  • 홍성호;김두현
    • Fire Science and Engineering
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    • v.17 no.3
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    • pp.26-30
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    • 2003
  • This paper presents a study on the analysis for false alarm of heat detector using HRR(Heat Release Rate). And it is represented to threshold value and domain of false alarm. The HRR threshold value of false alarm is calculated to use parameters obtained by small scale fire-experiment. The experiment is conducted to measure detector activation time and flame spread of wood cribs fire, etc. The results show that HRR threshold value of Fixed type detector is 20.24 kW and rate of rise type detector is 13.59 kW, respectively.

Analysis of Target Identification Performances Based on HRR Profiles against the Moving Targets (HRR Profile을 이용한 이동 표적에 대한 표적 식별 성능 분석)

  • Park, Jong-Il;Jung, Sang-Won;Kim, Kyung-Tae;Chun, Jong-Hoon;Bae, Jun-Woo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.3
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    • pp.289-295
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    • 2009
  • HRR(High Resolution Range) profiles show one-dimensional radar images including electromagnetic scattering phenomena of a target. Thus, they are not only robust to noise, but also easily obtainable in a real-time. However, in order to construct a training database for the success of radar target identification, a huge amount of HRR profiles are needed because HRR profiles are highly dependent on the relative angle between the radar and the target. In order to alleviate this difficulty, a database construction method based on the scenarios of target's movement is proposed. The proposed method is able to provide a reliable target identification performance even with a small amount of training database.

Association of Metabolic Syndrome with Exercise Capacity and Heart Rate Recovery after Treadmill Exercise Test

  • Shin, Kyung-A
    • Biomedical Science Letters
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    • v.17 no.4
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    • pp.305-311
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    • 2011
  • Heart rate recovery (HRR) immediately after a treadmill exercise test is a function of vagal reactivation. A delayed heart rate recovery is associated with an increased risk for overall cardiovascular mortality. The purpose of this study is to find out if metabolic syndrome is associated with autonomic nerve function and exercise capacity in healthy adults. We measured the treadmill exercise capacity (METs) and heart rate recovery in 119 subjects through a medical checkup at $J$ General Hospital. The metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) criteria. The value for the HRR was defined as the difference between the heart rate obtained during the peak exercise and the heart rate obtained at first minute during the recovery period. The subjects with the metabolic syndrome had significantly lower exercise duration ($9.6{\pm}1.5$ vs $8.7{\pm}1.4$), METs ($11.6{\pm}1.7$ vs $10.4{\pm}2.5$), and HRR ($37.5{\pm}14.3$ vs $27.1{\pm}8.9$). The waist circumference in subjects with the metabolic syndrome was more strongly correlated with HRR ($r$=-.517, $P$ <.001) than in normal subjects. Furthermore, delayed HRR was associated with high resting heart rate and increased waist circumference ($P$=.032, $P$ <.001, respectively). In conclusion, delayed HRR during the first minute after a treadmill exercise test was associated with the metabolic syndrome risk factors. Delayed HRR was also associated with high resting heart rate and increased waist circumference.

Heart Rate Recovery in Metabolically Healthy Obesity and Metabolically Unhealthy Obesity Korean Adults

  • Shin, Kyung-A
    • Biomedical Science Letters
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    • v.24 no.3
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    • pp.245-252
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    • 2018
  • Heart rate recovery (HRR) is simply an indicator of autonomic balance and is a useful physiological indicator to predict cardiovascular morbidity and mortality. The purpose of this study was to compare the differences in HRR between metabolically healthy obesity group and metabolically unhealthy obesity and to ascertain whether heart rate recovery is a predictor of metabolic syndrome. Metabolic syndrome was defined according to the standards of the National Cholesterol Education Program Adult Care Panel III. Obesity was assessed according to WHO Asian criteria. It was classified into three groups of metabolically healthy non-obesity group (MHNO, n=113), metabolically healthy obesity group (MHO, n=66), metabolically unhealthy obesity (MUO, n=18). Exercise test was performed with Bruce protocol using a treadmill instrument. There was no difference in HRR between MHO and MUO ($32.71{\pm}12.25$ vs $25.53{\pm}8.13$), but there was late HRR in MUO than MHNO ($25.53{\pm}8.13$ vs $34.51{\pm}11.80$). HRR in obese was significantly correlated with BMI (r=-0.342, P=0.004), waist circumference (r=-0.246, P=0.043), triglyceride (r=-0.350, P=0.003), HbA1c (r=-0.315, P=0.009), insulin (r=-0.290, P=0.017) and uric acid (r=-0.303, P=0.012). HRR showed a lower prevalence of abdominal obesity, hypertriglyceridemia, and low HDL-cholesterol in the third tertile than in the first tertile. In conclusion, MHO had no difference in vagal activity compared with MHNO, but MUO had low vagal activity. HRR is associated with metabolic parameters and is a useful predictor of abdominal obesity, hypertriglyceridemia, and low HDL-cholesterolemia.

The Implementation and Analysis of Facial Expression Customization for a Social Robot (소셜 로봇의 표정 커스터마이징 구현 및 분석)

  • Jiyeon Lee;Haeun Park;Temirlan Dzhoroev;Byounghern Kim;Hui Sung Lee
    • The Journal of Korea Robotics Society
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    • v.18 no.2
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    • pp.203-215
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    • 2023
  • Social robots, which are mainly used by individuals, emphasize the importance of human-robot relationships (HRR) more compared to other types of robots. Emotional expression in robots is one of the key factors that imbue HRR with value; emotions are mainly expressed through the face. However, because of cultural and preference differences, the desired robot facial expressions differ subtly depending on the user. It was expected that a robot facial expression customization tool may mitigate such difficulties and consequently improve HRR. To prove this, we created a robot facial expression customization tool and a prototype robot. We implemented a suitable emotion engine for generating robot facial expressions in a dynamic human-robot interaction setting. We conducted experiments and the users agreed that the availability of a customized version of the robot has a more positive effect on HRR than a predefined version of the robot. Moreover, we suggest recommendations for future improvements of the customization process of robot facial expression.

Measurement of Heat Release Rate by Carbon Dioxide Generation Method for Methane Fire (메탄화재의 이산화탄소 생성법에 의한 화재발열량 측정)

  • Kim, Sung-Chan
    • Fire Science and Engineering
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    • v.34 no.2
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    • pp.1-6
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    • 2020
  • The energy released by various burning material has a wide range of its magnitude and transient characteristics, the measurement of the heat release rate(HRR) has been considered as one of the most challenging issue among the parameters related to fire. This study compares the measured HRR calculated by the oxygen consumption (OC) method and the carbon dioxide generation (CDG) method using a laboratory-scale fire calorimeter. The feasibility of the CDG method is examined by analyzing the relative error. The relationship between the oxygen depletion factor and CO2 mass flow rate, which is a key parameter in HRR calculations, showed strong linearity at 6 % for the methane burner fire. The contribution of HRR by CO was less than 7% compared with the of HRR by CO2 in the CDG calculation method. The linearity of the OC and CDG methods with respect to HRR of the referenced methane burner in a quasi-steady state was less than 1%; this indicates that the CDG method can be utilized as a complementary method in heat release rate measurement.

Evaluation of Design Fire Curves for Single Combustibles in a Cinema Complex (복합영상관 단일 가연물의 디자인 화재곡선 평가)

  • Jang, Hyo-Yeon;Hwang, Cheol-Hong;Oh, Chang Bo;Nam, Dong-Gun
    • Fire Science and Engineering
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    • v.34 no.3
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    • pp.18-27
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    • 2020
  • An actual fire test was performed on single combustibles placed in a local cinema complex, and quantitative differences in the maximum heat release rate (HRR) and fire growth rate were investigated based on the design fire curve methods (i.e., the general and 2-stage methods). In terms of combustible use and fire load, a total of 12 combustibles were selected, classified into cinema lounge and movie theater. It was found that the maximum HRR and fire growth rate determined using the two-stage method were quantitatively different from those of the general method. The application of the two-stage method, which can be used to determine the fire growth rate of the initial fire stage more precisely, could be useful in accurately predicting the activation time of fire detectors and fire-extinguishing facilities, as well as the available safe egress time (ASET) and required safe egress time (RSET).

Numerical Analysis of the Effects of Droplets Characteristics of Water Spray on Fire Suppression (물 분무 액적 특성이 화재진압에 미치는 영향에 대한 수치해석)

  • Lee, Jaiho
    • Fire Science and Engineering
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    • v.33 no.6
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    • pp.1-8
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    • 2019
  • In this study, the effects of the characteristics of droplets of water spray on suppression of fire were analyzed numerically using fire dynamics simulator (FDS) 6.5.2. Additionally, the fire suppression characteristics by the water spray nozzle, including the extinguishing coefficient (EC), droplet size distribution function (SDF), median volumetric diameter (MVD), and droplets per second (DPS), were evaluated in terms of the decreasing normalized heat release rate (HRR) curve and cooling time. It was observed that with increase in the EC, the normalized HRR curve decreased rapidly, and the changing MVD affected the suppression of fire. In case of mono-disperse, the normalized HRR curve decreased slowly with the increase in DPS. On the contrary, in case of multi-disperse, the normalized HRR curve decreased rapidly even with a small increase in DPS.