• Journal of the Korean Society of Food Culture
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• v.18 no.2
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• pp.134-138
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• 2003

Quality stability of the herb pill coated with edible oils containing rosemary was investigated. Herb pills were made of herb powders such as Panax ginseng, Cinnamomum cassia, Lycium chinense, Zyzyphus jujuba and Zingiber officinale. Rapeseed oil and lubriol were used as edible coating oil. After herb pills coated with edible oils with or without rosemary were stored at $40^{\circ}C$ for 180 days, the microbial viable cell counts and peroxide values(POV) of the herb pill were investigated. After 180 day storage, POVs of herb pills with only rapeseed oil or lubriol were 0.51 and 0.49 meq/kg, respectively. However, when rosemary was added in herb pills the POVs were decreased to 0.30 and 0.39 meq/kg, respectively. The addition of rosemary to the rapeseed oil and lubriol tended to decrease the microbial viable cell counts of the herb pill. The microbial viable cell counts of rapeseed oil and lubriol were 940 and 820CFU/g, respectively after 180 days of storage. However, these levels were suppressed to 720 and 640CFU/g by the resemary addition. On the other hand, the ginseng saponin content of herb pills was not affected by the rosemary addition during storage.

• Proceedings of the Korean Society of Crop Science Conference
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• 2006.04a
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• pp.616-617
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• 2006

• YAKHAK HOEJI
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• v.50 no.5
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• pp.308-312
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• 2006

Alpinia katsumadai is used in traditional oriental medicine as an antiemetic and for treatment of stomach disorders. This study was to investigate the effect of the 50% methanol extract of Alpinia katsumadai and Puerariae thunbergiana on ethanol metabolism in rat. The administration of 50% methanol extract of Alpinia katsumadai significantly decrease the ethanol concentration in rat. The AUC and Cmax of Alpinia katsumadai was 3.1 and 2.4 times less than the control group, respectively. It was more effective than Pueraria thunbergiana is known to as ethanol detoxicant. Furthermore, we tested on its ethanol metabolizing effect with the preparation containing this herb (Haeju pill) in beagle. The AUC of Haeju pill was about 1.9 times less than the control group. It was estimated that the extract of Alpinia katsumadai had feasibility as a ethanol detoxication agent.

• Journal of agricultural medicine and community health
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• v.26 no.1
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• pp.57-64
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• 2001

A 23-year-old female has visited university hospital for abdominal colic and constipation. She took home-made herb pills for 15 days as a traditional remedy for skin eczema. On clinical examinations, conjunctiva was pale, sclera was icteric and lead line was visible on gingiva. Laboratory examinations are as follows; hemoglobin was 8.6g/$d{\ell}$, reticulocyte was 4.2% and there was basophilic stippling of erythrocytes in peripheral blood smear. Blood level of lead was elevated as $69{\mu}g/d{\ell}$. The herb pills contained 3.32% lead, with cumulative dose of lead over 3.2g. The herb pills were manufactured by a 70-year-old man who was not aware of the health hazard of lead. We suppose that he made herb pills with the imported raw materials from China that contained a high percentage of lead.

• Herbal Formula Science
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• v.14 no.1
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• pp.52-73
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• 2006

Objective & Methods: Toothache is occurred frequently in daily life. Nevertheless, medical treatment of the toothache is almost dependent on western cure. So we chose the oriental medicine textbook that were dealing with the internal herb medicine and external treatment. we got this result. Result were as follows : 1. The internal medication of toothache was the most used 15times Chungwesan(淸胃散) and 8times Palmihwan(八味丸). 2. Chungwesan (淸胃散) was used to remove the stomach heat. the intestin stomach heat and the stomach blood heat. etc. 3. The pill and powder form in external treatment was much used. 4. The most many used herb were Asari herba cum Radice(細辛), Cimicifugae Rhizoma( 升麻) and Angelicae dahurcae Radix(白芷), etc. 5. The most herb used for external treatment were the spicy warm and the spicy hot medication.

• Herbal Formula Science
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• v.25 no.4
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• pp.553-574
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• 2017

The purpose of this study is to find out effects of prescriptions according to the formula, manipulation of Rhei Rhizoma, configuration. The following results were reached through investigations on the prescriptions using Rhei Rhizoma as a main component. Objectives : Analysis of prescriptions According to the formula : Liquid Extract Prescriptions were used widely on three parts to treat fever and damp heat in the interior organs. Powder Prescriptions were taken with hot water, thin porridge, tea etc. to treat damp heat, congestion of phlegm, acute episodes. Liquid Mixed Pill treat congestion of QI, damp heat, phlegm. Honey Mixed Pill treat accumulated fever, distension, acute excessive fever. Paste Pill treat blood stagnation, excessive toxic-fever, epidemic diseases. External Application treat inflammation by injury, swelling due to severe fever by internal damage. Methods : Analysis of prescriptions According to the manipulation of Rhei Rhizoma : Prescriptions including Liquor processed Rhei Rhizoma treat excessive toxic-fever, congestion of phlegm, blocking orifices on the upper side. Steamed Rhei Rhizoma strengthen effects of making evacuate and cooling of heat. Processed Rhei Rhizoma with vinegar strengthen effects of removing blood stagnation by activating blood movement, releasing gathering. Results : Analysis of prescriptions According to the Composition of Rhei Rhizoma : 41% of the total prescriptions were on the area of less than 20%. In case of lower groups show increased frequency of combination with Pharbitidis Semen, Persicae Semen, Scutellariae Radix and manipulation of baking, steaming, roasting. In case of higher groups show increased frequency of treating excess syndrome, critical illness, acute severe illness, and using proccesed Rhei Rhizoma with vinegar. Treatment of damp heat on the liver and gallbladder, disorder of the spleen and stomach is done mostly by prescriptions on the area of less than 30%. Conclusions : Rhei Rhizoma-Coptidis Rhizoma pair treat damp heat, heat toxins in blood, and Constipation caused by excessive heat. Rhei Rhizoma-Glycyrrhizae Radix pair relieve effects of Rhei Rhizoma passing blocked feces, removing the poison, activating blood movement, releasing gathering with the effects of Glycyrrhizae Radix relaxing tension by harmonizing Middle. Rhei Rhizoma-Magnoliae Cortex pair are used to treat damp heat in middle area, excessive heat in the stomach and intestine. Rhei Rhizoma-Pharbitidis Semen pair act on both blood system and QI system treating edema, damp, stagnation, heat toxins, feces. Rhei Rhizoma-Persicae Semen pair treat blood stagnation with fever on blood system.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.9 no.1
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• pp.159-165
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• 1996

The study was clinically performed with the 128 out patients of dermatic disease who had visited the Dept. of dermatology, Dongzhimen Hospital, Beijing traditional medical college from May 2nd to February 14th 1996. The results were as follows. 1. The dermatologic findings which showed higher incidence in this study were Acne of Melasma 27 cases($21.0\%$), Psoriasis 25($19.5\%$), Eczema including Contact dermatitis 21($16.4\%$), Seborrheic dermatitis including Alopecia of hair 12($9.3\%$) and Urticaria 11($8.5\%$). 2. The sex ratio of male to female was 4.5 : 5.5. The peak incidence of age group was 30-39($21.8\%$). 3. In the duration of disease, 37 cases($28.9\%$) were between 1 year and 5 years. 27($21.1\%$) were over 10 years. 4. About the single herb drugs, they are Angelicas gigantis Radix, Paeoniae Radix and Salviae Radix in order of frequencies. In the case of pill type, Danggui gosam hwan. Chunggan hwan. Whaeo hwan and Shinnongjiyang hwan are most frequently used. In the case of topica, Whangyeongo, Juachanggo and Soeungo are used in high frequencies. 5. For the test and surgical treatment KOH surgical treatment of Molluscum contagiosum in 8 cases and the bloody treatment of Chronic psoriasis in 3 cases.

• Journal of Acupuncture Research
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• v.21 no.3
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• pp.265-282
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• 2004

Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed. Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.

• The Journal of Internal Korean Medicine
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• v.39 no.4
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• pp.550-569
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• 2018

Objectives: The purpose of this study was to investigate the effects of herbal medicine treatment for patients with migraine and to suggest research methods for herbal medicine treatment on migraine. Methods: In this study, a search was conducted through several academic sites using a combination of terms '편두통', 'Migraine', '한약', '한약치료', 'Herbal medicine', 'Herbal medicines', 'Herb', 'Traditional Chinese Medicine', and 'TCM'. Randomized controlled trials using herbal medicine treatments for adult patients with migraine were selected. Results: Ultimately, 46 papers were selected and analyzed. A statistically significant improvement was noted in the treatment group in terms of clinical migraine symptoms and other migraine evaluation tools before and after the herbal medicine treatment. Herbal medicines were administered in decoction, pill, and granule formulations. Many kinds of medicinal herbs, such as 解表藥類, 補益藥類, 淸熱藥類, 活血祛瘀藥類, and 平肝藥類, have been used for migraine. Among them, 川芎, belonging to 活血祛瘀藥類, is mentioned 36 times and is the most frequently used medicine. Herbal medicine was used safely for migraine treatment, without major adverse reactions, and the recurrence rate was significantly lower in the treatment group than in the control group. Conclusions: In conclusion, the herbal medicine treatment for patients with migraine showed a statistically significant improvement in 46 papers. Future studies should utilize standardized and objective evaluation tools, along with appropriate experimental design. The relevant articles should be increased to a significant level to verify the effect of herbal medicine treatments on migraine.

• Korean Journal of Oriental Medicine
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• v.18 no.1
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• pp.35-43
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• 2012

Objectives: Hypertension is the highest ratio among chronic disease in Korea, and the western medical information about hypertension is provided by many web sites. Advanced researches about hypertension have been conducted in Traditional Korean Medicine(TKM) for decades, but the research results are not arranged. So the results have not been utilized in following research nor contributed to the expansion of public knowledge. Methods : We did this study to improve this situation. In this study, we built database about advanced research articles related hypertension in TKM and implemented TKM information system of hypertension. Results : First, we benchmarked hypertension information systems and designed the TKM information system based on the benchmarking results and comments from TKM doctors. And it was composed of introduce, treatment, and etc. Second, we built prescription, herb, acumoxa, qigong, prevention/management, and pill database which is about 600 data extracted from papers and books. Third, we implemented JAVA/JSP based web information system which provides the database. And we created links for the each papers and books to use more easily. Conclusions : If we provide the research results about TKM hypertension diagnosis and combinational medication of western and oriental medicine, this information system will be more useful. And if we add internal and external project report about hypertension, it will be more worthy.