• Title/Summary/Keyword: Heritability

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Genomic Heritability of Bovine Growth Using a Mixed Model

  • Ryu, Jihye;Lee, Chaeyoung
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.11
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    • pp.1521-1525
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    • 2014
  • This study investigated heritability for bovine growth estimated with genomewide single nucleotide polymorphism (SNP) information obtained from a DNA microarray chip. Three hundred sixty seven Korean cattle were genotyped with the Illumina BovineSNP50 BeadChip, and 39,112 SNPs of 364 animals filtered by quality assurance were analyzed to estimate heritability of body weights at 6, 9, 12, 15, 18, 21, and 24 months of age. Restricted maximum likelihood estimate of heritability was obtained using covariance structure of genomic relationships among animals in a mixed model framework. Heritability estimates ranged from 0.58 to 0.76 for body weights at different ages. The heritability estimates using genomic information in this study were larger than those which had been estimated previously using pedigree information. The results revealed a trend that the heritability for body weight increased at a younger age (6 months). This suggests an early genetic evaluation for bovine growth using genomic information to increase genetic merits of animals.

Optimal population size to detect quantitative trait loci in Korean native chicken: a simulation study

  • Nwogwugwu, Chiemela Peter;Kim, Yeongkuk;Cho, Sunghyun;Roh, Hee-Jong;Cha, Jihye;Lee, Seung Hwan;Lee, Jun Heon
    • Animal Bioscience
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    • v.35 no.4
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    • pp.511-516
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    • 2022
  • Objective: A genomic region associated with a particular phenotype is called quantitative trait loci (QTL). To detect the optimal F2 population size associated with QTLs in native chicken, we performed a simulation study on F2 population derived from crosses between two different breeds. Methods: A total of 15 males and 150 females were randomly selected from the last generation of each F1 population which was composed of different breed to create two different F2 populations. The progenies produced from these selected individuals were simulated for six more generations. Their marker genotypes were simulated with a density of 50K at three different heritability levels for the traits such as 0.1, 0.3, and 0.5. Our study compared 100, 500, 1,000 reference population (RP) groups to each other with three different heritability levels. And a total of 35 QTLs were used, and their locations were randomly created. Results: With a RP size of 100, no QTL was detected to satisfy Bonferroni value at three different heritability levels. In a RP size of 500, two QTLs were detected when the heritability was 0.5. With a RP size of 1,000, 0.1 heritability was detected only one QTL, and 0.5 heritability detected five QTLs. To sum up, RP size and heritability play a key role in detecting QTLs in a QTL study. The larger RP size and greater heritability value, the higher the probability of detection of QTLs. Conclusion: Our study suggests that the use of a large RP and heritability can improve QTL detection in an F2 chicken population.

Differences in the heritability of craniofacial skeletal and dental characteristics between twin pairs with skeletal Class I and II malocclusions

  • Park, Heon-Mook;Kim, Pil-Jong;Sung, Joohon;Song, Yun-Mi;Kim, Hong-Gee;Kim, Young Ho;Baek, Seung-Hak
    • The korean journal of orthodontics
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    • v.51 no.6
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    • pp.407-418
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    • 2021
  • Objective: To investigate differences in the heritability of skeletodental characteristics between twin pairs with skeletal Class I and Class II malocclusions. Methods: Forty Korean adult twin pairs were divided into Class I (C-I) group (0° ≤ angle between point A, nasion, and point B [ANB]) ≤ 4°; mean age, 40.7 years) and Class II (C-II) group (ANB > 4°; mean age, 43.0 years). Each group comprised 14 monozygotic and 6 dizygotic twin pairs. Thirty-three cephalometric variables were measured using lateral cephalograms and were categorized as the anteroposterior, vertical, dental, mandible, and cranial base characteristics. The ACE model was used to calculate heritability (A > 0.7, high heritability). Thereafter, principal component analysis (PCA) was performed. Results: Twin pairs in C-I group exhibited high heritability values in the facial anteroposterior characteristics, inclination of the maxillary and mandibular incisors, mandibular body length, and cranial base angles. Twin pairs in C-II group showed high heritability values in vertical facial height, ramus height, effective mandibular length, and cranial base length. PCA extracted eight components with 88.3% in the C-I group and seven components with 91.0% cumulative explanation in the C-II group. Conclusions: Differences in the heritability of skeletodental characteristics between twin pairs with skeletal Class I and II malocclusions might provide valuable information for growth prediction and treatment planning.

DIVERGENT SELECTION FOR POSTWEANING FEED CONVERSION IN ANGUS BEEF CATTLE VI. REALIZED HERITABILITY ESTIMATES

  • Park, N.H.;Bishop, M.D.;Davis, M.E.
    • Asian-Australasian Journal of Animal Sciences
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    • v.7 no.4
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    • pp.475-479
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    • 1994
  • Postweaning performance data were obtained on 401 group fed purebred Angus calves from 24 selected sires (12 high and 12 low feed conversion sires) from 1983 through 1986 at the Northwestern Branch of the Ohio Agricultural Research and Development Center. A single generation divergent selection experiment was replicated four times (1983, 1984, 1985 and 1986) to obtain an realized heritability estimate for postweaning feed conversion. The 140-d postweaning period was divided into five 28-d periods. Realized heritability estimates for feed conversion by 28-d periods fluctuated greatly and demonstrated no particular pattern. Heritability was highest for the fourth period (between d 85 and 112 of postweaning period, 0.61). Thus, beef producers could successfully select for feed conversion.

A STUDY ON ESTIMATION OF HERITABILITY OF BIRTH WEIGHT AND WEANING WEIGHT OF TEDDY GOATS KEPT UNDER PAKISTANI CONDITIONS

  • Tahir, M.;Younas, M.;Raza, S.H.;Lateef, M.;Iqbal, A.;Raza, P.N.
    • Asian-Australasian Journal of Animal Sciences
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    • v.8 no.6
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    • pp.595-597
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    • 1995
  • The mean birth weight and weaning weight estimated from 777 kids from 30 bucks of Teddy goats were $1.67{\pm}0.31$ and $8.50{\pm}2.18kg$, respectively. The estimates of heritability of birth weight and weaning weight by half sib correlation method were $0.048{\pm}0.022$ and $0.101{\pm}0.012kg$, respectively. The high heritability estimates of birth weight indicates that selection on the basis of individual's own record will be effective. The low estimates of heritability of weaning weight indicates more emphasis should be given to improve environmental conditions for better achievement.

Heritability and Repeatability Estimates for Reproductive Traits of Japanese Black Cows

  • Oyama, K.;Katsuta, T.;Anada, K.;Mukai, F.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.12
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    • pp.1680-1685
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    • 2002
  • Reproductive data collected from more than 20,000 Japanese Black cows of Hyogo and Shimane Prefectures were analyzed. Averages of age at first calving, gestation length, days open and calving interval were 25.1 mo, 289 d, 112 d and 401 d, respectively. Variance components were obtained by REML procedure and the heritability estimate of age at first calving was 0.22. In gestation length the heritability estimate was 0.40 and no permanent environmental effect was estimated. Estimated variance components of calving interval were similar to those of days open and the heritability and repeatability of calving interval were 0.05 and 0.09, respectively. Random farm effects accounted for approximately 10% of phenotypic variations in all traits. Genetic and farm correlations between age at first calving and calving interval were 0.27 and 0.39, respectively. It was found that temporary environment was an important source of variation for calving intervals of Japanese Black.

Heritability Estimates under Single and Multi-Trait Animal Models in Murrah Buffaloes

  • Jain, A.;Sadana, D.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.5
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    • pp.575-579
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    • 2000
  • First lactation records of 683 Murrah buffaloes maintained at NDRI, Karnal which were progeny of 84 sires used for comparing the heritability estimates of age at first calving, first lactation milk yield and first service period under single and multiple trait models using restricted maximum likelihood (REML) method of estimation under an individual animal model. The results indicated that the heritability estimates may vary under single and multiple trait models depending upon the magnitude of genetic and environmental correlation among the traits being considered. Therefore, a single or multiple trait model is recommended for estimation of variance components depending upon the goal of breeding programme. However, there may not be any advantage of considering a trait with zero or near zero heritability and having no or very low genetic correlation with other traits in the model. Lower heritability estimates of part lactation yield (120-day milk yield) implied that there may not be any advantage of considering this trait in place of actual 305-day milk yield, whereas, comparable heritability estimates of predicted 305-day milk yield suggested that it could be used for sire evaluation to reduce the cost of milk recording under field conditions.

The Selection of combining crosses by heritability (유전력에 의한 교배조 선발시험)

  • 김원경
    • Journal of Sericultural and Entomological Science
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    • v.14 no.2
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    • pp.61-65
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    • 1972
  • The main purpose of this experiment is to select the best combining ability among KC${\times}$N13, and C20${\times}$N13 in view of the cocoon shell weight in Bombyx mori. In the spring of 1972, the author raised silkworms which were born from the crossing of the Chinese strain KC, C14, C20(female) with japanese strain N13 (male). Among each combining of crosses, the heritability of the cocoon shell weight was estimated by the method of variance analysis. The result of the experiment may he summarized as fellow; 1. For KC${\times}$N13 The cocoon shell was heavier than other combining crosses, but its heritability was lower than the others. The heritability of male moth was higher than that of female. 3. For C14${\times}$N13 The cocoon shell and the heritability was in medium value among the combining crosses, and the heritability of female moth was higher than that of male. 3. For C20${\times}$N13 The cocoon shell weigt was lower than the others, but its heritability was higher than that of others. In these combining crosses, C20${\times}$N13 is selected as a new race, which is much better than the commercial one, 103${\times}$104.

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SNP-based and pedigree-based estimation of heritability and maternal effect for body weight traits in an F2 intercross between Landrace and Jeju native black pigs (제주재래흑돼지와 랜드레이스 F2 교배축군의 생체중에 대한 유전체와 가계도 기반의 유전력 및 모체효과 추정)

  • Park, Hee-Bok;Han, Sang-Hyun;Lee, Jae-Bong;Kim, Sang-Geum;Kang, Yong-Jun;Shin, Hyun-Sook;Shin, Sang-Min;Kim, Ji-Hyang;Son, Jun-Kyu;Baek, Kwang-Soo;Cho, Sang-Rae;Cho, In-Cheol
    • Journal of Embryo Transfer
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    • v.31 no.3
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    • pp.243-247
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    • 2016
  • Growth traits, such as body weight, directly influence productivity and economic efficiency in the swine industry. In this study, we estimate heritability for body weight traits usinginformation from pedigree and genome-wide single nucleotide polymorphism (SNP) chip data. Four body weight phenotypes were measured in 1,105 $F_2$ progeny from an intercross between Landrace and Jeju native black pigs. All experimental animals were subjected to genotypic analysis using PorcineSNP60K BeadChip platform, and 39,992 autosomal SNP markers filtered by quality control criteria were used to construct genomic relationship matrix for heritability estimation. Restricted maximum likelihood estimates of heritability were obtained using both genomic- and pedigree- relationship matrix in a linear mixed model. The heritability estimates using SNP information were smaller (0.36-0.55) than those which were estimated using pedigree information (0.62-0.97). To investigate effect of common environment, such as maternal effect, on heritability estimation, we included maternal effect as an additional random effect term in the linear mixed model analysis. We detected substantial proportions of phenotypic variance components were explained by maternal effect. And the heritability estimates using both pedigree and SNP information were decreased. Therefore, heritability estimates must be interpreted cautiously when there are obvious common environmental variance components.