• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.1
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• pp.131-142
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• 2004

The purpose of this research was to investigate cytotoxity of Sunbanhwalmyungeum extract. Cytotoxity was determined by MTT assay method. After tumor cell lines(G361, BI6F10, MDA, A549) transplantation, the extracts of SunBangHwalMyungEum and its composition oriental medicines were administered, cytotoxity was measured by absorbance. The results were obtained as follows. 1. Sunbanhwalmyungeum extract and its composition oriental medicines extracts showed the concentration was higher, the more cytotoxity increased. 2. Both water and ethanol extracts of Sunbanhwalmyungeum showed excellent cytotoxity against G361, B16F10, MDA, A549 and high cytotoxity over 80$\%$ against G361, B16F10, MDA except A549 at the concentration of 1000ppm. 3. In water extract, Rhei Radix et Rhizoma, Gleditsiae Spina, Trichosanthis Radix, Glycyrrhizae Radix, Ledebouriellae Radix showed excellent cytotoxity. In ethanol extract, Gleditsiae Spina, Citri Pericarpium, Trichosanthis Radix, Paeoniae Radix Rubra, Myrrha showed excellent cytotoxity. 4. Rhei Radix et Rhizoma, Gleditsiae Spina, Trichosanthis Radix, Paeoniae Radix Rubra showed high cytotoxity in both water and ethanol extrats. 5. In water extract, Glycyrrhizae Radix, Ledebouriellae Radix, Myrrha showed high cytotoxity against A361, Lonicerae Flos, Olibanum, Fritillariae cirrhosae Bulbus, Paeoniae Radix Rubra, Manitis Squama against B16F10, Paeoniae Radix Rubra, Manitis Squama against MDA, Rhei Radix et Rhizoma, Angelicae gigantis Radix against A549. 6. In ethanol extract, Lonicerae Flos, Trichosanthis Radix showed high cytotoxity against G361, Rhei Radix et Rhizoma, Angelicae gigantis Radix, Gleditsiae Spina, Olibanum, Angelicae dahuricae Radix, Fritillariae cirrhosae Bulbus, Paeoniae Radix Rubra, Glycyrrhizae Radix, Ledebouriellae Radix, Myrrha against B16F10, Rhei Radix et Rhizoma, Manitis Squama against MDA, Citri Pericarpium, Manitis Squama against A549.

• Proceedings of the IEEK Conference
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• 2002.06b
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• pp.173-176
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• 2002

This paper is about a high-speed MAC (multiplier and accumulator) design applying radix-4 and radix-8 Booth's algorithm at the same time. The optimized hybrid radix design for high speed MAC has taken advantage of both a radix-4 and a radix-8 architectures. A radix-4 architecture meets high-speed, but it takes much more power and chip area than a radix-8 architecture. A radix-8 architecture needs less power and chip area than the other, but it has a bottleneck of generating three times the multiplicand problem. An optimized hybrid architecture performs the radix-4 multiplication partially in parallel with the generation of three times the multiplicand for use of the radix-8 multiplication. It reduces the concerned bit width of multiplier in radix-8 multiplication.

• Proceedings of the IEEK Conference
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• 2002.06a
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• pp.125-128
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• 2002

This paper is about a high-speed MAC (multiplier and accumulator) design applying radix-4 and radix-8 Booth's algorithm at the same time. The optimized hybrid radix design for high speed MAC has taken advantage of both a radix-4 and a radix-8 architectures. A radix-4 architecture meets high-speed, but it takes much more power and chip area than a radix-8 architecture. A radix-8 architecture needs less power and chip area than the other, but it has a bottleneck of generating three times the multiplicand problem. An optimized hybrid architecture performs tile radix-4 multiplication partially in parallel with the generation of three times the multiplicand for use of tile radix-8 multiplication. It reduces the concerned bit width of multiplier in radix-8 multiplication.

• Herbal Formula Science
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• v.24 no.1
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• pp.17-30
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• 2016

Objectives Rehmanniae Radix Preparata was prepared in the traditional Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine(Donguibogam)』 with a view to measuring the contents of 5-Hydroxymethyl-2-furaldehyde(5-HMF) at individual stages of steaming and sundrying and identifying new chemical components.Methods Based on the traditional Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine』, Rehmanniae Radix Preparata steamed and sundried once through nine times was prepared. Thereafter, 5-HMF contents were analyzed and new chemical components were identified in the Rehmanniae Radix Preparata using Waters HPLC e2695, 2640 detectors, a Waters Acquity UPLC system, and a Micromass Q-TOF Premier mass spectrometer.Results The Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine』 is a unique preparation method in Republic of Korea different from that in China. In the first stage of the method, fresh Rehmanniae Radix Crudus was divided into high quality, medium quality, and low quality ones named Rehmanniae Radix Crudus (Caelum)(天黃), Rehmanniae Radix Crudus (Homo)(人黃), and Rehmanniae Radix Crudus (Terra)(地黃) respectively to use Rehmanniae Radix Crudus (Caelum) and Rehmanniae Radix Crudus (Homo) for preparation of juice while using Rehmanniae Radix Crudus (Terra) to make Rehmanniae Radix Preparata. In the second stage, Rehmanniae Radix Crudus (Caelum) and Rehmanniae Radix Crudus (Terra) were made into juice and Rehmanniae Radix Crudus (Terra) was soaked in the juice. In the third stage, among auxiliary materials, rice wine named Purum Vinum Oryzae(淸酒) brewed from sticky rice was sprinkled on Rehmanniae Radix Crudus (Terra) to the extent that Rehmanniae Radix Crudus (Terra) became wet. In the fourth stage, Rehmanniae Radix Preparata steamed in earthenware steamer was dried under natural sunlight. The contents of 5-HMF in Rehmanniae Radix Preparata steamed and sundried once through nine times were shown to be below 0.1% in all cases. Pomolic acid was identified as a new chemical component.Conclusions In conclusion, the Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine』 is thought to be a unique preparation method in South Korea in which Rehmanniae Radix Preparata is completed through the first stage in which fresh Rehmanniae Radix Crudus collected from fields is divided into high, medium, and low quality ones and fresh Rehmanniae Radix Crudus juice is made, the second stage in which the high quality fresh Rehmanniae Radix Crudus is soaked in the fresh Rehmanniae Radix Crudus juice, the third stage in which the fresh Rehmanniae Radix Crudus is steamed, and the fourth stage in which the steamed Rehmanniae Radix Crudus is dried.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.3
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• pp.575-579
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• 2008

The purpose of this study was to investigate the effects of Astragali Radix on the diet-induced hyperlipidemia in rats. Hyperlipedemia was induced in rats with high fat diet. Rats were divided into 4 groups, normal group(supplied enough water and feeds only), high fat diet administered group(supplied high fat diet for 4 weeks, Control group) and Astragali Radix administered group(supplied high fat diet and Astragali Radix lyophilization extract for 4 weeks, 178.6 mg/kg(rat) in sample A, 297.8 mg/kg(rat) in sample B). Body weight, liver weight and serum lipid levels were evaluated. The water extract of Astragali Radix decreased body weight, liver weight, total cholesterol, LDL-cholesterol, triglyceride and phospolipid in high fat diet induced hyperlipidemia in rats, and increased HDL-cholesterol.

• Proceedings of the IEEK Conference
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• 2007.07a
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• pp.85-86
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• 2007

In this paper, a Radix-8 structure for high-speed FFT is proposed. Even throughput of the Radix-8 FFT is twice than that of the Radix-4 FFT, implementation area of the Radix-8 is larger than that of Radix-4 FFT. But, implementation area of the proposed Radix-8 FFT was reduced by using DA(Distributed Arithmetic) for multiplication. The Verilog-HDL coding results for the proposed FFT structure show 49.2% cell area increment comparison with those of the conventional Radix-4 FFT structure. Namely, to speed up twice, 49.2% of area cost is required. In case of same throughput, power consumption of the proposed structure is reduced by 25.4%.

• JSTS:Journal of Semiconductor Technology and Science
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• v.14 no.4
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• pp.407-418
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• 2014

As the high-throughput requirement in the next generation communication system increases, it becomes essential to implement high-throughput SISO (Soft-Input Soft-Output) decoder with minimal hardware resources. In this paper, we present the comparison results between cascaded radix-4 ACS (Add-Compare-Select) and LUT (Look-Up Table)-based radix-4 ACS in terms of delay, area, and power consumption. The hardware overhead incurred from the retiming technique used for high speed radix-4 ACS operation is also analyzed. According to the various analysis results, high-throughput radix-4 SISO decoding architecture based on simple path metric recovery circuit is proposed to minimize the hardware resources. The proposed architecture is implemented in 65 nm CMOS process and memory requirement and power consumption can be reduced up to 78% and 32%, respectively, while achieving high-throughput requirement.

• The Korean Journal of Food And Nutrition
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• v.8 no.3
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• pp.222-229
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• 1995

This study was conducted to investigate the effect of the Platycodi radix powder (PRP) and Platycodi radix saponin(PRS) on the reduction of lipid status In rats fed on high fat diet for 6 weeks after which lipid contents were measured in liver. And also by carrying out the histological examination throughout light microscope to observe the effects of fat accumulation reduction. The results obtained from this study are as fellows. In the levels of total lipid in liver, PRS Group significantly decreased compared with Contred Group, but PRP Group was not significantly changed. The content of triglyceride was tended to be slightly decreased in the PRP and PRS groups compared to the control group, which was not significant. It was observed from photomicrographs of hepatic tissue in rats that the PRP and PRS groups inhibits the lipid accumulation induced by high fat diets.

• Proceedings of the IEEK Conference
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• 2000.11b
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• pp.297-300
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• 2000

This paper proposes a high-speed and area-efficient FFT algorithm and performs a hardware implementation. This algorithm, named by “Radix-4/2”, uses the feature of existing radix-2$^3$algorithm, It reduces the number of non-trivial multipliers in SFG to the ratio of 3 to 2 campared with radix-2 or radix-4 algorithm and radix-4/2 has also twice throughput as radix-2$^3$algorithm's. It is proved that FFT processor using the proposed algorithm and 64-point MDC pipeline architecture has twice throughput as radix-2$^3$algorithm's, and reduces areas by 25 percentages in contrast to radix-4 algorithm's.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.5
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• pp.84-93
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• 2007

In this paper, a Radix-8 structure for high-speed FFT is propose. Main block of the proposed FFT structure is Radix-8 DIF(Decimation In Frequency) butterfly. Even throughput of the Radix-8 FFT is twice than that of the Radix-4 FFT, implementation area of the Radix-8 is larger than that of Radix-4 FFT. But, implementation area of the proposed Radix-8 FFT was reduced by using DA(Distributed Arithmetic) for multiplication. For comparison, the 64-point FFT was implemented using conventional Radix-4 butterfly and proposed Radix-8 butterfly, respectively. The Verilog-HDL coding results for the proposed FFT structure show 49.2% cell area increment comparison with those of the conventional Radix-4 FFT structure. Namely, to speed up twice, 49.2% of area cost is required. In case of same throughput, power consumption of the proposed structure is reduced by 25.4%. Due to its efficient processing scheme, the proposed FFT structure can be used in large size of FFT like OFDM Modem.