• Knowledge Management Research
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• v.11 no.1
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• pp.51-64
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• 2010

The exhibition and convention industries, which are recognized as industrial hub linked with many relational industries. It is important to prevent a excessive competition for convention centers among districts and to gain some benefit fairly. Each convention center needs a lot of convention to held in it's district. In order to obtain many conventions to held in Korea for many convention center, convention bureau has to manage the processes to attract convention with many collaborators using the convention hub-network system. We should, therefore, pay attention to construction of the convention Hub-Network system to activate the convention industries in the district. We lay out the critical design for three functions of the convention Hub-Network system using UML. Finally we show the demonstrative web pages that explain critical three functions.

• Korean Management Science Review
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• v.28 no.3
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• pp.1-13
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• 2011

Hub-and-spoke transportation network is a powerful and useful network structure that takes full advantage of economies of scale on routes between hubs. In recent studies, the network structure is extended to hybrid hub-andspoke that allows direct transportation between spokes. In this study, we considered more extended network structure which is called hybrid multiple hub-and-spoke that has multiple hubs and allows direct transportation between spokes. We developed a mathematical optimization model for automotive service parts transportation planning under hybrid multiple hub-and-spoke network structure. The model suggests a long-term transportation route planning and a short-term vehicle assignment planning. The model is verified by simulation and validated in real world application to Hyundai Mobis automotive service parts transportation planning. From the simulation result, the model reduced the transportation cost about 24.7%, the total distance about 6.8% and the CO2 emissions about 8.8%. In real world application for 6 months from July to December 2010, the model reduced the transportation cost about 9.1% by changing the long-term transportation route without daily vehicle assignment planning.

• Journal of the Korean Society for Railway
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• v.7 no.3
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• pp.264-270
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• 2004

The hub-and-spoke strategy is widely used in the field of transportation. At the field of rail transportation, however, it is difficult that we find an application case of this strategy because of modal characteristics. According to the fast growth of containerization and the development of transshipment technology, presently, the hub-and-spoke strategy is introduced by operators on actual European rail freight transportation. However, it is hardly to find empirical studies evaluating the applicability of transportation strategy. In this context, this study analyzed the applicabilities of hub-and-spoke strategy in the actual network of European rail freight. For the application and evaluation of the characteristics of hub-and-spoke strategy, it utilized a service network design model for rail freight. Utilizing this model, it analyzed the efficiency of furnished rail freight services, the potential locations of hubs, the characteristics of O-D flows by the types of trains and service links, and the types of paths of O-D flows. Finally, it proposed some implications and the further study topics.

• Proceedings of the Korea Association of Information Systems Conference
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• 2003.05a
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• pp.183-197
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• 2003

This paper introduces the public-oriented e-Hub construction for strategic alliances in the community. The public-oriented e-Hub can link with all Participating internet firms on the ba business models, and consequently help them share their core competence, management resource Based upon this perspective, this paper presents the procedures corresponding with social network strategic alliances of small and medium internet firms. In addition, this paper tries to analyze th among degree of competition, potential of strategic alliance, and financial performance. The resu the firms with more easily accepting various strategic alliances make higher financial performance competitive environment. This suggests that strategic alliances through the public-oriented e-Hub virtual community provide the internet firms with various opportunities

• Korean Management Science Review
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• v.20 no.1
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• pp.165-178
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• 2003

This paper introduces the public-oriented e-Hub construction for strategic alliances in the B2B virtual community. The public-oriented e-Hub can link with all participating Internet firms on the basis of their business models, and consequently help them share their core competence, management resources, and so on. Based upon this perspective, this paper presents the procedures corresponding with social network analysis for strategic alliances of small and medium internet firms. In addition, this paper tries to analyze the relationships among degree of competition, potential of strategic alliance, and financial performance. The results show that the firms with more easily accepting various strategic alliances make higher financial performance under more competitive environment. This suggests that strategic alliances through the public-oriented e-Hub in the B2B virtual community provide the internet firms with various opportunities.

• Journal of the Economic Geographical Society of Korea
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• v.12 no.4
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• pp.540-556
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• 2009

The hub and spoke network is a critical network-based infrastructure that is widely applied in current transportation and telecommunications systems, including Internets, air transportation networks and highway systems. This main idea of hub location models is to construct a network system which achieves the economy of scale of flows. The main purpose of this study is to introduce new hub location problems that take into account network reliability. Two standard models based on assignment schemes are proposed, and a minimum threshold model is provided as an extension in terms of hub network design. The reliability and interaction potentials of 15 nodes in the U.S. are used to examine model behaviors. According to the type of models and reliability, hubs, and minimum threshold levels, relationships among the flow economy of scale, network costs, and network resiliency are analyzed.

• Journal of the Korean Operations Research and Management Science Society
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• v.31 no.2
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• pp.141-155
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• 2006

In this paper, we address an extended hub-and-spoke transportation network design problem (EHSNP). In the existing hub location problems, the location and number of spokes, and shipments on spokes are given as input data. These may, however, be viewed as the variables according to the areas which they cover. Also, the vehicle routing in each spoke needs to be considered to estimate the network cost more correctly. The EHSNP is a problem of finding the location of hubs and spokes, and pickup/delivery routes from each spoke, while minimizing the total related transportation cost in the network. The EHSNP is an integrated problem that consists of several interrelated sub-problems. To solve EHSNP, we present an approach based on a symbiotic evolutionary algorithm (symbiotic EA), which are known as an efficient tool to solve complex integrated optimization problems. First, we propose a framework of symbiotic EA for EHSNP and its genetic elements suitable for each sub-problem. To analyze the proposed algorithm, the extensive experiments are performed with various test-bed problems. The results show that the proposed algorithm is promising in solving the EHSNP.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.22 no.4
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• pp.15-24
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• 2014

Low Cost Carrier(LCC)s in Asia Pacific market are expected to record high growth due to the expansion of Open Sky Policy among Korea, Japan, China and South East Asia. As everybody is aware of, LCC is not only saving flight cost but also creates differentiating business model by reducing unnecessary services such as F&B and in-flight duty free sales services. Booming LCCs in Asian market will cause not only Incheon airport but also other local airports in Korea to compete heavily to attract LCCs. For example, Air Asia Group with more than 200 fleet has expanded its alliance network throughout Asia. Therefore this paper has researched a new business model operating a LCC terminal for the hub airport competitiveness. According to analysis result of case study, it was found out, considering increasing airline demand next decade, Incheon airport and other domestic airports in Korea had better change an existing terminal into a LCC Terminal(LCCT) to differentiate airport services and expand its hub network. That is because of economic feasibility, first of all, of securing hub and spoke networking capabilities with airlines and finally of developing commercial facilities customizing LCC passengers' demand.

• The Journal of the Korea Contents Association
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• v.8 no.6
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• pp.74-81
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• 2008

Protein interaction network contains a small number of highly connected protein, denoted hub and many destitutely connected proteins. Recently, several studies described that a hub protein is more likely to be essential than a non-hub protein. This phenomenon called as a centrality-lethality rule. This nile is widely credited to exhibit the importance of hub proteins in the complex network and the significance of network architecture as well. To confirm whether the rule is accurate, we Investigated all protein interaction DBs of yeast in the public sites such as Uetz, Ito, MIPS, DIP, SGB, and BioGRID. Interestingly, the protein network shows that the rule is correct in lower scale DBs (e.g., Uetz, Ito, and DIP) but is not correct in higher scale DBs (e.g., SGD and BioGRID). We are now analyzing the features of networks obtained from the SGD and BioGRD and comparing those of network from the DIP.

• Genomics & Informatics
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• v.19 no.2
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• pp.16.1-16.14
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• 2021

Even in the current age of advanced medicine, the prognosis of malignant peritoneal mesothelioma (MPM) remains abysmal. Molecular mechanisms responsible for the initiation and progression of MPM are still largely not understood. Adopting an integrated bioinformatics approach, this study aims to identify the key genes and pathways responsible for MPM. Genes that are differentially expressed in MPM in comparison with the peritoneum of healthy controls have been identified by analyzing a microarray gene expression dataset. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses of these differentially expressed genes (DEG) were conducted to gain a better insight. A protein-protein interaction (PPI) network of the proteins encoded by the DEGs was constructed using STRING and hub genes were detected analyzing this network. Next, the transcription factors and miRNAs that have possible regulatory roles on the hub genes were detected. Finally, survival analyses based on the hub genes were conducted using the GEPIA2 web server. Six hundred six genes were found to be differentially expressed in MPM; 133 are upregulated and 473 are downregulated. Analyzing the STRING generated PPI network, six dense modules and 12 hub genes were identified. Fifteen transcription factors and 10 miRNAs were identified to have the most extensive regulatory functions on the DEGs. Through bioinformatics analyses, this work provides an insight into the potential genes and pathways involved in MPM.