• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.7 no.5
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• pp.72-84
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• 1998

In order ot study the influence of a circular inclusion on a stress field near a crack tip, mutual interference of a slant crack and the circular inclusion is analyzed of a bimaterial inclusion. As the crack emanates at the equivalent slant crack angle the correction factors FⅠ and FⅡ for the inclusion wit small Young's modulus were found to decrease as the inclusion radius increased. The correction factors for inclusion with large Young's modulus increase as the inclusion radius increases at the equivalent radius of the inclusion, the correction factors decrease as the slant crack angle increases for the aspect ratio $\frac{c}{W}$ = 0.1 irrespective of the Young's modulus. For $\frac{c}{W}$ greater than 0.2, they increase as the slant crack angle increases. There is no influence of stress mutual interfce after crack emanates beyond the inclusion radius.

• Journal of Microbiology and Biotechnology
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• v.6 no.4
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• pp.225-231
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• 1996

The production of recombinant proteins in Escherichia coli often leads to the formation of an intracellular inclusion body. Key process steps that can determine the economics of large-scale protein production from inclusion bodies are fermentation, inclusion body recovery, and protein refolding. Compared with protein refolding and fermentation, inclusion body recovery has received scant research attention. Nevertheless, it can control the final product yield and hence process cost for some products. Optimal separation of inclusion bodies and cell debris can also aid subsequent operations by removing contaminant particulates that foul chromatographic resins and contain antigenic pyrogens. In this review, the properties of inclusion bodies and cellular debris are therefore examined. Attempts to optimise the centrifugal separation of inclusion bodies and debris are also discussed.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.6
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• pp.1474-1482
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• 1994

In order to study the influence of a circular inclusion on a stress field neat a crack tip, mutual interference of a crack and the circular inclusion is analyzed by using the two dimensional boundary element method program made for the analysis of a bimaterial inclusion. The stress intensity factor of an inclusion which has small stiffness is a little greater than that of large stiffness in the near-by crack tip, and similar values tends to appear for distant crack tips. A line crack shows the repetition phenomena which caused by stress mutual interference depending on the radius and stiffness of an inclusion, and the repetition phenomena becoms weak in the inclusion which has large stiffness. Stress mutual interference shows repetition phenomena after extension of a line crack by the length of the radius of the inclusion which has small stiffness.

• Journal of the Korean Society for Precision Engineering
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• v.14 no.7
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• pp.22-28
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• 1997

In this paper, We have studied internal quality incluiding chemical compositions, microscopic structure and nonmetalic inclusion of test material. We have analyzed dynamic characteristics of cutting resistence and compared chip treatment of the test material. In analyzing internal quality, all of the test material have typical ferrite+pearlite structure. But, nonmetallic inclusion has oxide and sulfide inclusion has oxide and sulfide inclusion in medium carbon steel, mainly sulfide inclusion is existed in S-free cutting steel. In Ca+S-free cutting steel, calcium aluminate and sulfide complex inclusion, had low-melting point, as deformation of sulfide and oxide inclusion is existed. Machining characteristics, cutting resistence is maximum in medium carbon steel. Chip treatement are excellent in S-free cutting steel, similar to the Ca+S free cutting steel and medium carbon steel.

• Korean Journal of Food Science and Technology
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• v.35 no.2
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• pp.266-271
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• 2003

Insoluble polyphenol antioxidants, quercetin and catechin, were stabilized through the complexation with cyclodextrin to increase heat and pH stabilities. Comparison of inclusion complex formabilities of quercetin and catechin with ${\alpha}-,\;{\beta}-$, and ${\gamma}-CDs$ revealed ${\beta}-CD$ to be the most suitable result. Optimal molar mixing ratio of ${\beta}-CD$ and quercetin or catechin for inclusion complex formation was found to be 1 : 1. Inclusion complexation was confirmed using differential scanning calorimetry. Solubility of ${\beta}-CD-antioxidant$ inclusion complexes increased compared with native antioxidants, Stability against temperature and pH of ${\beta}-CD-antioxidant$ inclusion complex analyzed revealed antioxidant activities of ${\beta}-CD-quercetin$ and catechin inclusion complexes have higher stabilization compare to raw quercetin and catechin. Peroxide value of linoleic acid dissolved in water decreased substantionally after using ${\beta}-CD-quercetin$ inclusion complex. ${\beta}-CD-antioxidant$ inclusion complex can be used effectively as a fresh-food preservative.

• Journal of Pharmaceutical Investigation
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• v.34 no.4
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• pp.269-274
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• 2004

To enhance the solubility and stability of lansoprazole (LAN), new proton pump inhibitor, we were prepared various molar ratio of inclusion complex with $2-hydroxypropyl-{\beta}-cyclodextrin$ (HPCD) and organic alkali agent, meglumine (MEG). Inclusion complex formation of LAN with HPCD was investigated by Differential Scanning Calorimetry and X-ray diffractometry. The aqueous solubilities of inclusion complexes, and the stabilities of 1:4 and 1:5 inclusion complexes in aqueous solutions containing different concentrations of MEG were examined. The stability of 1:5 LAN-HPCD inclusion complex containing MEG, which was equaled to amount of LAN, was performed in 0.9% NaCl and 5% dextrose solution. The formation of inclusion complex of LAN with HPCD was $A_L$ type and the molar ratio of complex was 1:1. The stability constant was $41.557\;M^{-1}$. As molar ratio of LAN to HPCD was increased, solubility of inclusion complex was increased. 1:5 LAN-HPCD inclusion complex was more stable than 1:4 LAN-HPCD inclusion complex. And as contained MEG amount in LAN solution was increased, stability of 1:4 and 1:5 LAN-HPCD inclusion complexes was improved. Also stability of 1:5 LAN-HPCD-MEG inclusion complex in 0.9% NaCl solution and 5% dextrose solution was similar to it in water at room temperature, but it was unstable at $40^{\circ}C$.

• Journal of the Korean Society for Precision Engineering
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• v.14 no.8
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• pp.137-145
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• 1997

A two-dimensional program for the analysis of bimaterial inclusion has been developed using the bound- ary element method. In order to study the effects of circular inclusion on the stress field of the crack tip, numerical analysis was performed for the straight crack of finite length around the symmetric circular inclusion whose modulus of elasticity was different from that of the matrix material. In the case of inclusion whose stiffness was smaller than that of the matrix material, the stress intensity factor was found to increase as the crack enamated. The stress intensity factor was uninfluenced from the radial change in inclusion and remained constant for the stiffness equivalent to the matrix materials, where as it decreased for the inclusion with larger stiffness. For the vareation in the distance of the inclusion, a small increase in the stress intensity factor was observed for the case with small or equal stiffness compared with the matrix materials. The inclusion with larger stiffness showed a gradual decrease in the strss intensity factor as the crack emanated.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.12
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• pp.363-370
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• 2021

This study aims to revisit the issues and misconceptions about financial inclusion (FI) indices. For indices construction, this study uses two approaches: one approach following the methodology of Sarma (2008) which is based on UNDP methodology, while the other is the Dynamic Factor Model (DFM)-based index of Stock and Watson (2002) and Rehman et al. (2021). The data of 18 economies of Asia from 1997 till 2017 is used for indices construction and analysis. The authors constructed macro and micro-level financial inclusion indices based on the different types of financial inclusion indicators. Second, the authors have critically evaluated two different approaches, and the results show that Sarma (2008)-based index show financial inclusion's level, while DFM-based index reveal fluctuation in the current year's financial inclusion level due to the prior variations. For measuring the level of financial inclusion, the Sarma (2008) index is effective, while for forecasting the level of financial inclusion, the DFM approach is more appropriate. Furthermore, the micro and macro aspects of financial inclusion should be reflected in separate indices for better understanding and in-depth insights.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.12
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• pp.19-29
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• 2021

This study aims to measure financial inclusion and examine its impact on income inequality in a panel of 18 Asian countries over the period 1997-2017. Two alternative approaches for developing financial inclusion index are used: one approach following the methodology of Sarma (2008), while the other is the Dynamic Factor Model (DFM)-based index. The impact of individual indicators and index of financial inclusion on inequality in income is analyzed. The Generalized Method of Moment (GMM) approach is used for empirical analysis. The results indicate that micro-level financial inclusion has a weak negative and statistically significant impact on income inequality. Macro-level index and all individual indicators of financial inclusion do not affect income inequality in the selected sample of economies. The income inequality issues have different natures and cannot be fixed by financial inclusion only. It needs holistic structural reforms to enable fair distribution of income and make an equitable financial system. Financial inclusion is a relatively less important intervention tool regarding fixing the issue of income inequality. This is one of the first studies that used the DFM method for financial inclusion indices construction.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1996.04a
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• pp.97-101
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• 1996

In this paper, We have studied internal quality incluiding chemical compositions, microscopic structrue and nonmetalic inclusion of test materials. We have analyzed dynamic characteristics of cutting resistence including tensile strength value, hardeness value, impact value etcs. We have compared chip treatments of test materials. In analyzing internal quality, all of test materials have typical ferrite+pearlite structure. But, nonmetallic inclusion have oxide and sulfide inclusion in medium carbon steels, mainly sulfide inclusion is existed in S-free cutting steels. In Ca+S-free cutting steels, calcium aluminate and sulfide complex inclusion, had low-melting points, as deformation of sulfide and oxide inclusion is existed. machining characteristics, cutting resistence is maximum in Ca+S-free cutting steels, minimum in medium carbon steels. Chip treatements are excellent in S-free cutting steels, similar to the Ca+S free cutting steels and medium carbon steels.