• Title/Summary/Keyword: Inhomogeneous

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Application of the Homogenization Analysis to Calculation of a Permeability Coefficient (투수계수 산정을 위한 균질화 해석법의 적응)

  • 채병곤
    • Journal of Soil and Groundwater Environment
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    • v.9 no.1
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    • pp.79-86
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    • 2004
  • Hydraulic conductivity along rock fracture is mainly dependent on fracture geometries such as orientation, aperture, roughness and connectivity. Therefore, it needs to consider fracture geometries sufficiently on a fracture model for a numerical analysis to calculate permeability coefficient in a fracture. This study performed new type of numerical analysis using a homogenization analysis method to calculate permeability coefficient accurately along single fractures with several fracture models that were considered fracture geometries as much as possible. First of all, fracture roughness and aperture variation due to normal stress applied on a fracture were directly measured under a confocal laser scaning microscope (CLSM). The acquired geometric data were used as input data to construct fracture models for the homogenization analysis (HA). Using the constructed fracture models, the homogenization analysis method can compute permeability coefficient with consideration of material properties both in microscale and in macroscale. The HA is a new type of perturbation theory developed to characterize the behavior of a micro inhomogeneous material with a periodic microstructure. It calculates micro scale permeability coefficient at homogeneous microscale, and then, computes a homogenized permeability coefficient (C-permeability coefficient) at macro scale. Therefore, it is possible to analyze accurate characteristics of permeability reflected with local effect of facture geometry. Several computations of the HA were conducted to prove validity of the HA results compared with the empirical equations of permeability in the previous studies using the constructed 2-D fracture models. The model can be classified into a parallel plate model that has fracture roughness and identical aperture along a fracture. According to the computation results, the conventional C-permeability coefficients have values in the range of the same order or difference of one order from the permeability coefficients calculated by an empirical equation. It means that the HA result is valid to calculate permeability coefficient along a fracture. However, it should be noted that C-permeability coefficient is more accurate result than the preexisting equations of permeability calculation, because the HA considers permeability characteristics of locally inhomogeneous fracture geometries and material properties both in microscale and macroscale.

T1-201 Per Rectum Scintigraphy in Chronic Liver Disease: Assessment of T1-201 Uptake Indices (만성 간질환에서의 T1-201 경직장 문맥 신티그라피: T1-201 섭취 지표의 평가)

  • Moon, Won-Jin;Choi, Yun-Young;Cho, Suk-Shin;Lee, Min-Ho
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.1
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    • pp.49-56
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    • 1999
  • Purpose: Heart to liver ratio on T1-201 per rectal scintigraphy (shunt index) is known to be useful in the assessment of portal systemic shunt. We assessed T1-201 uptake pattern and early liver/heart uptake rate of T1-201 and correlated with shunt index in patients with chronic active hepatitis (CAH) and liver cirrhosis (LC). Materials and Methods: Fifty eight patients with biopsy-proven chronic liver disease (35 with CAH, 23 with LC) underwent T1-201 per rectum scintigraphy after instillation of 18.5 MBq of T1-201 into the upper rectum. We evaluated hepatic uptake (type 1 : homogeneous, 2: inhomogeneous segmental, 3: inhomogeneous nonsegmental) and extrahepatic uptake of spleen, heart and kidney (grade 0: no uptake, 1: less than liver, 2: equal to liver, 3: greater than liver). We measured the early liver/heart uptake rate (the slope of the liver to heart uptake ratio for 10 min) and shunt index (heart to liver uptake ratio). T1-201 uptake pattern and early liver/heart uptake rate of T1-201 was correlated with the pathologic diagnosis and shunt index. Results: Hepatic uptake patterns of type 1 and 2 were dominant in CAH (CAH: 27/35, LC. 8/23), and type 3 in LC (CAH: 8/35, LC: 15/23)(p<0.005). The grades of extrahepatic uptake were higher in LC than in CAH (spleen: p<0.001, other soft tissue: p<0.005). The early liver/heart uptake rate of CAH ($0.110{\pm}0.111$) was significantly higher than that of LC ($0.014{\pm}0.090$)(p<0.001). The sensitivity and specificity of the early liver/heart uptake rate were 77.7% and 67.7% in differentiating LC from CAH. There was negative correlation between early liver/heart uptake rate and shunt index (r=-0.3347, p<0.01). Conclusion: Hepatic and extrahepatic uptake pattern and early liver/heart uptake rate on T1-201 per rectum scintigraphy are useful in the assessment of portal systemic shunt in patients with chronic liver disease.

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MR Imaging Findings of Uterine Cervical Adenocarcinoma (자궁경부 선암종의 자기공명영상 소견)

  • 김종철
    • Investigative Magnetic Resonance Imaging
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    • v.2 no.1
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    • pp.113-119
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    • 1998
  • Purpose : Because adenocarcinomas of the uterine cervix have lower 5-year survival rate than squamous cell carcinomas due to early lymph node metastasis and local extension, scrutiny of lymph node metastasis and local extension by radiologic examination is necessary in case of clinically diagnosed or suspected adenocarcinomas. The purpose of this study is to evaluate whether there are specific findings of these tumors, compared with squamous cell carcinomas, through the analysis of magnetic resonance (MR) imaging findings. Materials and Methods : Of 21 pathologically proven cervical adenocarcinomas, MR imaging findings of 18 tumors (histologic staging : two Ib, four IIa, two IIb, one IIIa, and one IIIb) were retrospectively analyzed and compared with those of 40 wquamous cell carcinoma in consecutive patients as a control group. T1-wetighted and fast spin echo T2-weighted images were obtained on the axial and sagittal planes, using a 1.5-T MR scanner. The largest diameter, location, signal intensity and degree of contrast enhancement contour, shape and longitudinal extent of the tumor and associated findings on MR image were analyzed. Results : The largest diameters of cervical adenocarcinomas ranged from 0.8 to 4.1 cm(mean, 2.2 cm). Of 18 adenocarcinomas, nine were of endocervical type. All adenocarcinomas were isointense to surrounding cervical stroma on T1-weighted images and hyperintense(homogeneous in ten, inhomogeneous in eight) on fast spin echo T2-weighted images. Adenocarcinomas enhanced on contrast study in all patients (homogeneous in six, inhomogeneous in 12 with hyperintese enhnacing rim in two). Eight adenocarcinomas had smooth contours and ten had irregular ones. The shape of adenocarcinoma was irregular in eight patients, barrel shape in six, papillary/polypod in three, and nodular in one. All adenocarcinomas involved lower half of the uterine cervix and six tumors extended up to the upper half. Pelvic lymph nodes of more than 1.5cm in diameter in two adenocarcinomas pateints and no detectable small pelvic lymph nodes on MR imaging in one patient were pathologically positive. Hydrometra was associated in two adenocarcinomas patients, and hematometra in one patient. Compared with squamous cell carcinomas, more frequent MR findings of endocervical type and barrel shape in cervical adenocarcinomas were statistically significant. Conclusion : Cervical adenocarcinomas had more frequent MR findings of endocervical type and barrel shape, compared with wquamous cell carcinomas. Adenocarcinoma of the uterine cervix may be suspected on MR imaging, when a cervical carcinoma is of barrel shape along the endocervical canal and tends to involve lymth nodes in earlier stages.

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A Case of Bronchus-Associated Lymphoid Tissue(BALT) Lymphoma in the Lung of the Patient with Primary Sj$\ddot{o}$gren's Syndrome (원발성 쇼그렌 증후군(Primary Sj$\ddot{o}$gren's Syndrome) 환자에서 발생한 Bronchus-Associated Lymphoid Tissue(BALT) 림프종 1례)

  • Kang, Min-Jong;Lee, Jae-Myung;Lee, Seung-Joon;Son, Jee-Woong;Kim, Dong-Gyu;Lee, Myung-Goo;Hyun, In-Gyu;Jung, Ki-Suck
    • Tuberculosis and Respiratory Diseases
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    • v.52 no.2
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    • pp.179-185
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    • 2002
  • A bronchus-associated lymphoid tissue(BALT) lymphoma of the lung is a rare disorder of patients with Sj$\ddot{o}$gren's syndrome. A 49-year-old woman was admitted for an evaluation of exertional dyspnea and general weakness which had persisted for two years. The patient had suffered from dry mouth and dry eyes for five years. The physical examinations showed a coarse breath sound with inspiratory crackles on the whole lung field, particularly on the both basal lungs. The laboratory data disclosed high titers of anti-nuclear antibodies, and anti-SSA (Ro), and anti-SSB (La) antibodies. Chest radiographs demonstrated the presence of bilateral, diffuse, reticulonodular densities in both lungs. Thin-section CT scans showed diffusely distributed mosaic pattern of an inhomogeneous attenuation extending over the entire lung zone. The histological findings from an open-lung biopsy specimen revealed an accumulation of lymphoid cells around the bronchioles and an extension of malignant lymphoma cells from the bronchiolar epithelium toward the alveolar space. Immunohistochemically, the neoplastic cells reacted positively to the CD 20 antigen and were focally positive for the UCHL 1 antigen. The histological diagnosis was consistent with a low grade marginal zone B-cell lymphoma originating in the BALT. Here, we present a case of a histologically proven BALT lymphoma of the lung in a patient with primary Sj$\ddot{o}$gren's Syndrome.

A study on image distortion improvement using silicon device in thyroid diffusion MRI images (갑상선의 확산강조영상 검사 시 실리콘 이용한 뒤틀림 감소에 관한 연구)

  • Choi, Kwan-Woo;Seo, Dae-Keon;Lee, Ho-Beom;Goh, Hee-Jin;Na, Sa-Ra;Han, Dong-Kyoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.7
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    • pp.4380-4386
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    • 2014
  • This study was conducted to minimize the imaging distortion by reducing the differences in susceptibility between the tissue and air surrounding it while performing a thyroid diffusion imaging procedure. The study group was composed of 23 healthy adults. Thyroids with many distortions near the air, larynx, and trachea were chosen to test and evaluate the diffusion imaging difference between before and after an application of silicon. As a result, there was reduced distortion with silicon application, and the differences decreased from 30% to 10%. According to One-way ANOVA and Duncan's post-hoc test, there were no significant differences between imaging with a silicon application and T2 imaging of the surface area, which was the standard image. In conclusion, this study presented a radical improvement in reducing the distortions in imaging by compensating for an uneven tissue surface near air without affecting the magnetic resonance contrast and complicating the imaging processes.

Viscoelastic Behavior of High Density Polyethylene Using High Tibial Osteotomy with Respect to the Strain Rate (근위경골절골술(HTO)용 X-밴드 플레이트에 적용되는 고밀도 폴리에틸렌(HDPE)의 변형률속도에 따른 점탄성거동)

  • Hwang, Jung-Hoon;Kim, Cheol-Woong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.4
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    • pp.431-438
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    • 2012
  • The mechanical behavior of the polymeric material, HDPE depends on both time and temperature. The study of the tensile behavior at different strain rates is important in engineering design of the orthopedics device such as X-band plate. The mechanical properties and deformation mechanisms of HDPE are strongly dependent on the applied strain rate. Generally, the deformation behavior of HDPE based on the stress-strain curve is complex because of the highly inhomogeneous nature of plastic deformation, particularly that of necking. Therefore, we attempted to determine the mechanical behavior of HDPE in this study. Normally, tensile testing under various strain rates of the HDPE has been used to determine the mechanical behavior. We performed tensile tests at various strain rates (1 to 500 %/min) to analyze the viscoelastic behavior on increasing the strain rate. A tensile stress-strain curve was plotted from the data, and the point of transition was marked to calculate the transition stress, strain, and modulus.

Synthesis and characterization of perovskite nano-sized (Pb, La)$TiO_3$ powder using mechano chemical process (기계화학공정을 이용한 Perovskite 구조의 (Pb, La)$TiO_3$ 나노 분말 합성 및 특성)

  • Lim, Bo-Ra-Mi;Yang, Jae-Kyo;Lee, Dong-Suk;Noh, Tae-Hyung;Seo, Jung-Hye;Lee, Youn-Seoung;Kim, Hee-Taik;Choa, Yong-Ho
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.18 no.5
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    • pp.200-204
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    • 2008
  • Mechano Chemical Process (MCP) skips the calcinations steps at an intermediate temperature that is always required in the conventional solid-state reaction because forming phase from raw powder is activated by mechanical energy. In this study, we prepared (Pb, La)$TiO_3$ nanopowder with perovskite structure by only high energy MCP. Especially, the PLT nanopowder was synthesized without any thermal treatment using oxides, not salts as raw powder. This process is also very simple due to dry milling method, unnecessary to dry of powder. The oxide powder was milled up to 12 hr at intervals of an hour using MCP and the pure PLT phase of perovskite structure was formed after milling time of 3 hr. And the average particle size was 20 nm with narrow distribution after milling time of 3 hr from raw powder of several $\mu m$ with inhomogeneous distribution.

SURFACE CHARACTERISTICS AND BIOLOGICAL RESPONSES OF HYDROXYAPATITE COATING ON TITANIUM BY HYDROTHERMAL METHOD: AN IN VITRO STUDY

  • Kim, Dong-Seok;Kim, Chang-Whe;Jang, Kyung-Soo;Lim, Young-Jun
    • The Journal of Korean Academy of Prosthodontics
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    • v.43 no.3
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    • pp.363-378
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    • 2005
  • Statement of problem. Hydroxyapatite(HA) coated titanium surfaces have not yet showed the reliable osseointegration in various conditions. Purpose. This study was aimed to investigate microstructures, chemical composition, and surface roughness of the surface coated by the hydrothermal method and to evaluate the effect of hydrothermal coating on the cell attachment, as well as cell proliferation. Material and Methods. Commercially pure(c.p.) titanium discs were used as substrates. The HA coating on c.p. titanium discs by hydrothermal method was performed in 0.12M HCl solution mixed with HA(group I) and 0.1M NaOH solution mixed with HA(group II). GroupⅠ was heated at 180 $^{\circ}C$ for 24, 48, and 72 hours. GroupⅡ was heated at 180 $^{\circ}C$ for 12, 24, and 36 hours. And the treated surfaces were evaluated by Scanning electron microscopy(SEM), Energy dispersive X-ray spectroscopy(EDS), X-ray photoelectron spectroscopy(XPS), X-ray diffraction method(XRD), Confocal laser scanning microscopy(CLSM). And SEM of fibroblast and 3-(4,5- dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assay were used for cellular responses of the treated surfaces. Results. The color of surface changed in both groups after the hydrothermal process. SEM images showed that coating pattern was homogeneous in group II, while inhomogeneous in group I. H72 had rosette-like precipitates. The crystalline structure grew gradually in group II, according to extending treatment period. The long needle-like crystals were prominent in N36. Calcium(Ca) and phosphorus(P) were not detected in H24 and H48 in EDS. In all specimens of group II and H72, Ca was found. Ca and P were identified in all treated groups through the analysis of XPS, but they were amorphous. Surface roughness did not increase in both groups after hydrothermal treatment. The values of surface roughness were not significantly different between groups I and II. According to the SEM images of fibroblasts, cell attachments were oriented and spread well in both treated groups, while they were not in the control group. However, no substantial amount of difference was found between groups I and II. Conclusions. In this study during the hydrothermal process procedure, coating characteristics, including the HA precipitates, crystal growth, and crystalline phases, were more satisfactory in NaOH treated group than in HCl treated group. Still, the biological responses of the modified surface by this method were not fully understood for the two tested groups did not differ significantly. Therefore, more continuous research on the relationship between the surface features and cellular responses seems to be in need.

Dielectric Characteristics of Gaseous $SF_6$ for Impulse Voltages in Presence of a Metallic Particle in GIS (가스절연개폐장치에 있어서 금속입자 존재시 임펄스전압에 대한 $SF_6$가스의 절연특성)

  • 이복희;이경옥;이창준
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.14 no.1
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    • pp.22-29
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    • 2000
  • This paper deals with the dielectric characteristics of $SF_6$ gas gap stressed by $\pm$1.2/44[$mutextrm{s}$] non-oscillating impulse and $\pm$0.4[$mutextrm{s}$]/1.14[MHz] oscillating impulse voltages in the presence of a needle-shape metallic particle in gas-insulated switchgear(GIS). Breakdown voltage-time (V-t) and breakdown voltage-gas pressure (V-p) characteristics were investigated and discussed. The experiments were carried out under highly inhomogeneous field geometry with a needle protrusion whose length and radius are 10[mm] and 0.5[mm], respectively. The gas pressure ranges from 0.1 to 0.5[㎫]. As a result, it was found that the electrical breakdown for both the positive and negative polarity develops with steplike pulses in leader mechanism, When subjected to the positive oscillating impulse voltage, the minimum breakdown voltages appeared in all the gas pressure ranges and the V-t curves have a pronounced upturning at short times to breakdown and give a little dependence of the gas pressure. On the other hand, in the case of the negative polarity the dependence of the V-t and V-p characteristics on the wave shape of the applied voltages is known to be appreciable.

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Magnetic Resonance Imaging of Lumen Wall using Quadrature-typed Inside-out Receiver Coil (회전자계 역수신 코일을 이용한 관벽의 자기공명 영상)

  • 문치웅;조종운
    • Journal of Biomedical Engineering Research
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    • v.22 no.5
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    • pp.385-392
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    • 2001
  • This study Proposes a quadrature-typed inside-out receiver coil to obtain magnetic resonance(MR) images of lumen wall. This means that the coil should receive the signals from out-side of receiver coil. This coil has wide and uniform sensitive region to compare with previous coils such as anti-solenoid coil, octal-pole coil and so on. These coils have the disadvantages that sensitive region is narrow and inhomogenous. The proposed coil is consist of two saddle coils of which directions are orthogonal to one another. The sensitivity maps of octal-Pole coil single-saddle coil and quadrature-typed inside-out coil were obtained by computer simulation. And phantom images for each coil were obtained to evaluate the performances of the coil using both 1.5T superconducting and 0.3 Permanent magnet MRI system. The uniformity of quadrature coil's sensitivity map was superior to that of octal-polel coil. Experimentally measured SNR of quadrature coil is also 36% higher than that of single-saddle coil This study shows the possibility of quadrature-typed inside-out receiver coil for the MR lumen wall images.

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