• Korean Journal of Remote Sensing
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• v.17 no.2
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• pp.111-119
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• 2001

This study analyzes time variability of the normalized difference vegetation index (NDVI), the leaf area index (LAI) and surface temperature (Ts) estimated from AVHRR data collected from across the Korean peninsula from 1981 to 1994. In the present study, LAI defined as vegetation density, as a function of NDVI applied for the vegetation types and Ts defined by the split-window formulation of Becker and Li (1990) with emissivity of a function of NDVI, are used. Results of the inter-annual, intra-annual and intra-seasonal variabilities in Korea show: (1) Inter-annual variability of NDVI is generally larger in the southem and eastern parts of the peninsula than in the western part. This large variability results from the significant mean variation. (2) Inter-annual variability of Ts is larger in the areas of smaller NDVI. This result shows that the NDVI play a small role in emissivity. (3) Inter-annual variability of LAI is larger in the regions of higher elevation and urban areas. Changes in LAI are unlikely to be associated with NDVI changes. (4) Changes in NDVI and Ts are likely dominant in July and are relatively small in spring and fall. (5) Urban effect would be obvious on the time-varying properties of NDVI and Ts in Seoul and the northern part of Taejon, where NDVI decreases and Ts increases with a significant magnitude.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.22 no.3
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• pp.225-232
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• 2019

Purpose: To evaluate intra- and inter-observer variability and guideline adherence amongst pediatricians in treating children aged between 4 and 18 years referred with recurrent abdominal pain (RAP) without red flags. Methods: The first part of the study is a retrospective single-center cohort study. The diagnostic work-ups of eight pediatricians were compared to the national guidelines. Intra- and inter-observer variability were examined by Cramer's V test. Intra-observer variability was defined as the amount of variation within a pediatrician and inter-observer variability as the amount of variation between pediatricians in the application of diagnostic work-up in children with RAP. Prospectively, the same pediatricians were requested to provide a report on their management strategy with a fictitious case to prove similarities in retrospective diagnostic work-up. Results: A total of 10 patients per pediatrician were analyzed. Retrospectively, a (very) weak association between pediatricians' diagnostic work-ups was found (0.22), which implies high inter-observer variability. The association between intra-observer diagnostic was moderate (range, 0.35-0.46). The Cramer's V of 0.60 in diagnostic work-up between pediatricians in the fictitious case implied the presence of a moderately strong association and lower inter-observer variability than in the retrospective study. Adherence to the guideline was 66.8%. Conclusion: We found a high intra- and inter-observer variability and moderate guideline adherence in daily clinical practice amongst pediatricians in treating children with RAP in a teaching hospital.

• Speech Sciences
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• v.15 no.1
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• pp.63-72
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• 2008

Various acoustic features were extracted and analyzed to estimate the inter- and intra-speaker variability of emotional speech. Tokens of vowel /a/ from sentences spoken with different modes of emotion (sadness, neutral, happiness, fear and anger) were analyzed. All of the acoustic features (fundamental frequency, spectral slope, HNR, H1-A1 and formant frequency) indicated greater contribution to inter- than intra-speaker variability across all emotions. Each acoustic feature of speech signal showed a different degree of contribution to speaker discrimination in different emotional modes. Sadness and neutral indicated greater speaker discrimination than other emotional modes (happiness, fear, anger in descending order of F-ratio). In other words, the speaker specificity was better represented in sadness and neutral than in happiness, fear and anger with any of the acoustic features.

• Korean Journal of Clinical Pharmacy
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• v.16 no.2
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• pp.155-164
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• 2006

Great inter-variability in drug response and adverse drug reactions is related to inter-variability of drug bioavailability, drug interaction and patient's disease and physyological state that cause change in absorption, distribution, metabolism and excretion of drugs. However, these alone do not sufficiently predict and explain inter-variability in drug response. In recent studies, it is reported that inter-variability in drug response and adverse drug reactions may largely resulted from genetically determined differences in drug absoption, distribution, metabolism and drug target proteins. Especially, the major human drug-metabolizing enzymes such as CYP450, N-acetyl tranferase, thiopurine S-methyl transferase, glutathione S-transferase are identified as the major gene variants that cause inter-individual variability in drug's response and adverse drug reactions. These variations may have most significant implications for those drugs that have narrow therapeutic index and serious adverse drug reactions. Therefore, the genetic variation such as polymorphisms in drug metabolizing enzymes can affect the response of individuals to drugs that are used in the treatment of depression, psychosis, cancer, cardiovascular disorders, ulcer and gastrointestinal disorders, pain and epilepsy, among others. This review describes the pharmacogenomics of the drug metabolizing enzymes associated with the drug response and its clinical applications.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.11
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• pp.739-746
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• 2013

Variability of the software product line that differentiates member products within a product line must be described with precise meaning and visualized so as easy to select. Moreover, it should be easy to manage. Variability description approaches can largely be divided into two approaches, integrated variability description approach and orthogonal variability description approach. Orthogonal Variability Description Language (OVDL) was developed for clear and precise description of variability without ambiguity. This paper validates the variability description capability of OVDL by translating the variability models of Inter-Working Function (IWF) product line described by using Orthogonal Variability Model (OVM) notations into variability descriptions in OVDL.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.9
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• pp.1691-1699
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• 1992

The experimental results of fatigue crack propagation under constant amplitude loading show that intra-and inter-specimen variability exist. In this paper, a stochastic model for the estimation of mean and variance of crack propagation life is presented To take into account the intra-specimen variability, the material resistance against crack propagation is treated as an 1-dimensional spatial stochastic process, i. e. random field, varying along the propagation path. For the inter-specimen variability, C in paris equation is assumed to be a random variable. Compared with experimental results reported, the present method well estimate the variation in fatigue crack propagation life. And it is confirmed that the thicker the specimen thickness is, the less the variation of propagation life is.

• Journal of Ocean Engineering and Technology
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• v.24 no.6
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• pp.97-102
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• 2010

This paper deals with the variability of short term creep rupture time based on previous creep rupture tests and the statistical methodology of the creep life prediction. The results of creep tests performed using constant uniaxial stresses at 600, 650, and $700^{\circ}C$ elevated temperatures were used for a statistical analysis of the inter-specimen variability of the short term creep rupture time. Even under carefully controlled identical testing conditions, the observed short-term creep rupture time showed obvious inter-specimen variability. The statistical aspect of the short term creep rupture time was analyzed using a Weibull statistical analysis. The effect of creep stress on the variability of the creep rupture time was decreased with an increase in the stress level. The effect of the temperature on the variability also decreased with increasing temperature. A long term creep life prediction method that considers this statistical variability is presented. The presented method is in good agreement with the Lason-Miller Parameter (LMP) life prediction method.

• Journal of Environmental Science International
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• v.22 no.10
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• pp.1305-1316
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• 2013

A long-term wind resource map was made to provide the key design data for the 2.5 GW Korean West-South Offshore Wind Project, and its reliability was validated. A one-way dynamic downscaling of the MERRA reanalysis meteorological data of the Yeongwang-Gochang offshore was carried out using WindSim, a Computational Fluid Dynamics based wind resource mapping software, to establish a 33-year time series wind resource map of 100 m x 100 m spatial resolution and 1-hour interval temporal resolution from 1979 to 2012. The simulated wind resource map was validated by comparison with wind measurement data from the HeMOSU offshore meteorological tower, the Wangdeungdo Island meteorological tower, and the Gochang transmission tower on the nearby coastline, and the uncertainty due to long-term variability was analyzed. The long-term variability of the wind power was investigated in inter-annual, monthly, and daily units while the short-term variability was examined as the pattern of the coefficient of variation in hourly units. The results showed that the inter-annual variability had a maximum wind index variance of 22.3% while the short-term variability, i.e., the annual standard deviation of the hourly average wind power, was $0.041{\pm}0.001$, indicating steady variability.

• MALSORI
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• v.55
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• pp.119-130
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• 2005

The aim of this paper is to investigate some acoustical characteristics of the voice quality features from the emotional speech database. Six different parameters are measured and compared for 6 different emotions (normal, happiness, sadness, fear, anger, boredom) and from 6 different speakers. Inter-speaker variability and intra-speaker variability are measured. Some intra-speaker consistency of the parameter change across the emotions are observed, but inter-speaker consistency are not observed.

• Phonetics and Speech Sciences
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• v.9 no.3
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• pp.25-32
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• 2017

Besides their effect on the f0 contour of the following vowel, Korean stops are undergoing a sound change in which a partial or complete consonantal merger on voice onset time (VOT) is taking place between aspirated and lax stops. Many previous studies on sound change have mainly focused on group-normative effects, that is, effects that are representative of the population as a whole. Few systematic quantitative studies of change in adult individuals have been carried out. The current study examines whether the sound change holds for individual speakers. It focuses on inter-speaker and intra-speaker variability on sound change in contemporary Korean. Speech data were collected for thirteen Seoul Korean speakers studying abroad in America. In order to minimize the possible effects of speech production, socio-phonetic factors such as age, gender, dialect, speech rate, and L2 exposure period were controlled when recruiting participants. The results showed that, for nine out of thirteen speakers, the consonantal merger is taking place between the aspirated and lax stop in terms of VOT. There were also intra-speaker variations on the merger in three aspects: First, is the consonantal (VOT) merger between the two stops is in progress or not? Second, are VOTs for aspirated stops getting shorter or not (i.e., the aspirated-shortening process)? Third, are VOTs for lax stops getting longer or not (i.e., the lax-lengthening process)? The results of remarkable inter-speaker and intra-speaker variability indicate a synchronous speech sound change of the stop system in contemporary Korean. Some speakers are early adopters or active propagators of sound change whereas others are not. Further study is necessary to see whether the inter-speaker differences exceed intra-speaker differences in sound change.