• Title/Summary/Keyword: Korean medicine text Inje-ji

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Systematic network analysis of herb formula in Traditional East Asian Medicine discloses synergistic operation of medicinal herb pairs with statistical significance

  • Lee, Jungsul;Jeon, Jongwook;Choi, Chulhee
    • CELLMED
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    • v.5 no.2
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    • pp.11.1-11.5
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    • 2015
  • Traditional East Asian Medicine (TEAM) prescriptions typically consist of several herbs based on the assumption that the herbs operate synergistically and/or cooperate on several related pathways simultaneously. This is a general concept that is widely accepted in TEAM, but it has not been tested systematically. To check this assumption statistically, we have text mined traditional Korean medicine text the Inje-ji(仁濟志, Collections of benevolent savings), a text that contains more than 5000 herb-cocktail prescriptions. We created herb-pairing network based on herb-herb pairing specificity and performed a systematic network analysis. Herbs were shown to be used selectively with other herbs and not randomly. Moreover, herb pairs were more specifically associated with symptoms than were single herbs. Single herbs and combinations of herbs specifically used for diabetes mellitus were successfully identified. As conclusion, herb-pairings in TEAM are not randomly constructed; instead, each herb was selectively used with other herbs. In terms of statistical significance, herb pairs were more specifically associated with symptoms than were single herbs alone. Collectively, these results suggest that it may be important to understand the interactions among multiple ingredients contained in herb pairs rather than trying to identify a single compound to resolve symptoms.

A Study on the 'Tangaek-Unhoei(湯液韻彙)' Index of Herbal Medicine in the Inje-Ji(仁濟志) of the Imwon-Gyeongje-Ji(林園經濟志), by Seo-Yugu(徐有榘) Focusing on 'Fang(方)' (풍석(楓石) 서유구(徐有榘)의 『임원경제지(林園經濟志)』 「인제지(仁濟志)」 '탕액운휘(湯液韻彙)'와 처방 제형에 대한 연구 - '방(方)'을 중심으로 -)

  • JEON, Jongwook
    • Journal of Korean Medical classics
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    • v.36 no.4
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    • pp.25-40
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    • 2023
  • Objectives : This paper studies the Tangaek-Unhoei(湯液韻彙) index of herbal medicine in the Inje-Ji(仁濟志) of the Imwon-Gyeongje-Ji(林園經濟志), which contains about 4,800 formulas. Created by 19th-century Joseon scholar Seo, Yugu, it not only lists the formulas according to their names, but also provides index by topic, which enabled the collection and effective application of massive medical information. Methods : We quantitatively examined the nearly 4,800 herbal medicines in the Tangaek-Unhoei and their categorization. Any uncommon or particular categorization was examined further by analyzing the original text. Results & Conclusions : The prescriptions contained in the Inje-Ji are categorized under 26 headings. They are listed according to the 106 units of the Chinese character dictionary and organized by double headings. This unique index makes it easy to browse the contents of such a vast book containing massive medicinal knowledge. In addition, the fifty or so remedies called 'Fang(方)' exemplify the author's attitude toward medicinal knowledge, which is both rational and inclusive. This is an attitude that should be recognized beyond tradition.

Characteristics of Cellular Phone Use and its Association with Psychological Problems among Adolescents (청소년의 휴대 전화 사용 실태 및 정신과적 문제와의 연관성)

  • Lee, Myung-Ji;Lee, Jeong-Seop;Kang, Min-Hee;Kim, Chul-Eung;Bae, Jae-Nam;Choo, Jung-Suk
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.21 no.1
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    • pp.31-36
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    • 2010
  • Objective : We investigated the characteristics of cellular phone use and its association with psychological problems among adolescents. Methods : A total of 332 adolescent students were recruited for this study. The participants' self-reported characteristics of cellular phone use and the psychological problems caused by this were tested by using the Excessive Cellular Phone Use Survey (ECPUS), the Children's Depression Inventory (CDI), Spielberger's State-Trait Anxiety Inventory for Children (STAIC) and the Korea-Youth Self Report (K-YSR). Results : The excessive user group made more use of text messages and they spent more time and paid higher fees than the comparison group. They expressed severer depression and anxiety and they had more behavior problems and lower school performance than the comparison group. The ECPUS score was positively correlated with score of the CDI, STAIC and the behavior problem scales of the K-YSR, and the ECPUS score was negatively correlated with the school performance scale of the K-YSR. Conclusion : Our findings suggest that excessive cellular phone use by adolescents may be related to psychological problems. Careful education about the use of cellular phones and intervention are recommended for adolescents who excessively use cellular phones.