• Journal of Periodontal and Implant Science
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• v.25 no.1
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• pp.1-13
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• 1995

Chlorhexidine and Listerine are widely used in dentistry due to its effectiveness on plaque control and bactericidal action. The effects of these agent on chronic gingivitis and wound healing following surgical periodontal therapy in human has been favorable. Understanding the effects of chlorhexidine and Listerine on human gingival fibroblast will provide the rationale for its use during the healing process of periodontal surgery. The purpose of this study was to compare the effects of chlorhexidine and Listerine on human gingival fibroblast. Human gingival fibroblasts were cultured from the healthy gingiva on the extracted premolar of orthodontic patients. Human gingival fibroblast were trypsinized and cultured in growth medium added range of 0.0012-0.12% chlorhexidine and 1-100% Listerine mouth wash solution. The cell used in this study were between fifth to eighth passage number. The cell morphology were examined by inverted microscope and the cell activity were measured by MIT assay. The Morphology of gingival fibroblast added Chlorhexidine and Listerine at the concentration of all range were became globular and lost their cytoplasmic process. Our results indicate that a 0.0012 concentration of chlorhexidine and 1% concentration of Listerine were shows minimal cytotoxicity, but above these concentraion, there was a significant difference between the cell activity in the experimental group and control group(p

• Journal of dental hygiene science
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• v.11 no.5
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• pp.397-404
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• 2011

The aims of this study were to evaluate the effect of native acidity upon dental hard tissues by measuring pH in mouth-rinse, which is on the market, and to evaluate even influence of dental stain caused by mouse-rinse given using for a long time. The experimental group was used Garglin, Nextcare, Listerine, and Hexamedin. The control group was used sterile distilled water. As a result, pH was indicated to be low in Nextcare(4.70) and Listerine(4.16). In a change of color tone, $b^*$ value of indicating Yellow-blue showed the lower value than the early color tone in all groups. There was statistical significance in Nextcare and Listerine. ${\Delta}L^*$ value of indicating light -dark gets darker after using Nextcare, Listerine and Hexamedine. A change(VHN) in surface hardness of enamel showed reduction in surface hardness after 14 days in Nexcare and Listerine. As a result of confirming a change in enamel surface by using Scanning Electron Microscopy, the erosion aspect on the enamel surface could be confirmed in groups of Nexcare and Listerine. Ra value in surface roughness of enamel could be observed the enamel surface, which got rougher compared to other experimental groups.

• Journal of dental hygiene science
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• v.23 no.4
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• pp.351-360
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• 2023

Background: The purpose of this study is to investigate the tooth whitening effect of Listerine Healthy White and provide effective management of extrinsic discoloration by comparing the whitening effects of existing whitening products. Methods: The included study four groups: those using whitening gel, whitening toothpaste, and Listerine Healthy White and a control using artificial saliva. Each group received 40 bovine tooth specimens, which were stained with commonly consumed tooth-coloring-inducing foods; black tea, black coffee, and instant noodles for 72 hours. The specimens were treated with tooth whitening materials for 5 weeks, after which the lightness (L^*) was measured weekly using a spectrophotometer. Results: There was a significant difference in lightness among the groups between the 1st and 5th week of treatment for all tooth-coloring-inducing foods (p<0.05). When comparing the changes in lightness values from before whitening to the 5th week of whitening for all tooth-coloring-inducing foods, the order of change was as follows: whitening gel, whitening toothpaste, Listerine Healthy White, and artificial saliva. Listerine Healthy White showed a significant whitening effect for all tooth-coloring-inducing foods (p<0.05). Particularly, changes in lightness values for specimens stained by black tea after 5 weeks of whitening were in the following order: whitening gel (21.72), whitening toothpaste (14.89), Listerine Healthy White (12.91), and artificial saliva (3.85). For specimens stained by black coffee, the changes in lightness values were in the following order: whitening gel (12.99), whitening toothpaste (9.66), Listerine Healthy White (7.91), and artificial saliva (3.12). Lastly, changes in lightness values for specimens stained by instant noodles were as follows: whitening gel (10.84), whitening toothpaste (9.85), Listerine Healthy White (7.71), and artificial saliva (2.61). Conclusion: Listerine Healthy White exhibits continuous whitening effects over time, and for consumers seeking convenient ways to achieve tooth whitening effects at home, consistent use of Listerine Healthy White is recommended.

• Restorative Dentistry and Endodontics
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• v.34 no.6
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• pp.500-507
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• 2009

The purpose of this study is to compare the antibacterial effect of $Listerine^{(R)}$ on two microorganisms (P. gingivalis and E. faecalis) with various root canal irrigants (NaOCl, CHX, EDTA) and to identify possibility of using $Listerine^{(R)}$ as a root canal irrigant. Porphyromonas gingivalis ATCC 3327 and Enterococcus faecalis ATCC 29212 were used in this experiment. For the test irrigants, 0.5%, 1%, 2.5%, 5.25% NaOCl, 0.1%, 0.2%, 1%, 2% CHX, 0.5M EDTA (18.6% EDTA) and $Listerine^{(R)}$ were prepared. Distiled water was used as control. Two methods-1) Comparison of turbidity in broth and 2) Agar diffusion test-were used to determine the extent of antibacterial effect of $Listerine^{(R)}$ and to compare it with that of NaOCl, CHX, and EDTA. All solutions tested were effective against two bacterial strains compared with control (p < 0.001). Any concentration of NaOCl, CHX, and EDTA showed similarly high effectiveness against all bacterial strains. In all experiment, $Listerine^{(R)}$ showed significantly low antibacterial effect compared with the other root canal irrigants (p < 0.05). In conclusion, the results reflect remarkably low antibacterial effect of $Listerine^{(R)}$ as compared with root canal irrigants in general so it is not suitable for the root canal irrigant.

• Journal of Periodontal and Implant Science
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• v.24 no.2
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• pp.406-420
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• 1994

The purpose of this study was to compare the effects of Chlorhexidine, Listerine and hypertonic saline mouthrinse without periodontal pack during 2 weeks following periodontal surgery. Twelve patients were treated with modified Widman flap procedures. Each fourth patients assigned to chlorhexidine mouthrinse group, Listerine mouthrinse group and control group. Each group wasn't significant difference in clinical and microbiologic parameters at preoperation. Examination regarding plaque index, gingival index, pocket depth, change of gingival color postsurgically, pain index and contrast phase microscope were performed. Evaluations were made at the first, the second and the fourth weeks postsurgically. The results were as follows: 1. Chlorhexidine mouthrinse group and Listerine mouthrinse group were significantly different in plaque index at the first, the second and the fourth weeks 2. The pocket depth of three groups were significantly reduced at the fourth weeks. 3. Chlorhexidine mouthrinse group and Listerine mouthrinse group were significantly different in change of gingival color at the first week. 4. Cocci and non-motile rods were increased at the first and the second weeks. But, motile rods and spirochete were increased at the fourth weeks.

• Imaging Science in Dentistry
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• v.44 no.2
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• pp.149-154
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• 2014

Purpose: This study assessed the effectiveness of three antimicrobial mouthrinses in reducing microbial growth on photostimulable phosphor (PSP) plates. Materials and Methods: Prior to performing a full-mouth radiographic survey (FMX), subjects were asked to rinse with one of the three test rinses ($Listerine^{(R)}$, $Decapinol^{(R)}$, or chlorhexidine oral rinse 0.12%) or to refrain from rinsing. Four PSP plates were sampled from each FMX through collection into sterile containers upon exiting the scanner. Flame-sterilized forceps were used to transfer the PSP plates onto blood agar plates (5% sheep blood agar). The blood agar plates were incubated at $37^{\circ}C$ for up to 72 h. An environmental control blood agar plate was incubated with each batch. Additionally, for control, 25 gas-sterilized PSP plates were plated onto blood agar and analyzed. Results: The mean number of bacterial colonies per plate was the lowest in the chlorhexidine group, followed by the Decapinol, Listerine, and the no rinse negative control groups. Only the chlorhexidine and Listerine groups were significantly different (p=0.005). No growth was observed for the 25 gas-sterilized control plates or the environmental control blood agar plates. Conclusion: The mean number of bacterial colonies was the lowest in the chlorhexidine group, followed by the Decapinol, Listerine, and the no rinse groups. Nonetheless, a statistically significant difference was found only in the case of Listerine. Additional research is needed to test whether a higher concentration (0.2%) or longer exposure period (two consecutive 30 s rinse periods) would be helpful in reducing PSP plate contamination further with chlorhexidine.

• Journal of Periodontal and Implant Science
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• v.20 no.2
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• pp.164.2-164.2
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• 1990

• Journal of Periodontal and Implant Science
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• v.28 no.4
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• pp.631-646
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• 1998

The purpose of this study was to access the clinical effects of C31G, Listerine and CPC on the earlyx periodontitis when they were used as a adjunctives to the mechanical plaque control. Each groups were composed of 12 patients and in three test groups, C31G(Exp 1 group), Listerine(Exp 2 group) and CPC mouthrinse(Exp 3 group) were used three times a day. and as a control, placebo solution was used. Plaque index, gingival index, bleeding index, pocket depth and loss of attachment were measured as clinical parameters. After scaling and oral hygiene instruction, root planing is done two weeks later. During the eight weeks of experimental period, mouth gargling is done by all groups. The changes in the clinical parameters of the all sites were monitored every two weeks. The results were as follows : 1. The plaque index showed a siginificant difference in Exp 1 group compared with test 2 group after 2 weeks use of mouth rinse(P<0.05). 2. The gingival index showed a significant difference in Exp 1 group compared with baseline value(P<0.05) but there was no significant difference between the groups after 2 weeks use of mouthrinse (P<0.05). 3. The plaque index, gingival index and bleeding index showed a significant difference in all groups compared with baseline value after 4 weeks of root planing and mouthrinse use(P<0.05). but there was no significant difference between the groups(P<0.05). 4. Periodontal pocket depth showed a significant difference in all groups compared with baseline value after 4 weeks of root planing and mouthrinse use(P<0.05). and there was significant difference between the Exp 1 group and control group(P<0.05). 5. Loss of attachment showed a significant difference in all Exp groups compared with baseline value after 4 weeks of root planing and mouthrinse use(P<0.05). and there was significant difference between the Exp 1 group and control group(P<0.05). The results suggest that C31G, Listerine and CPC were effective for early periodontitis as a adjunctive to mechanical plaqe control.

• The Journal of Advanced Prosthodontics
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• v.13 no.2
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• pp.100-106
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• 2021

PURPOSE. The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against Candida albicans. Materials and methods: This study used tablet-type denture cleansers, PolidentⓇ, CoolingdentⓇ and FittydentⓇ, along with liquid denture cleansers, HexamedineⓇ, ListerineⓇ and Apple vinegarⓇ. The antibacterial activities of denture cleansers were evaluated based on the number of C. albicans and concentrations of the denture cleansers. Results. In the 0.5 × 106 cfu/㎖ culture medium, the C. albicans' death rate of PolidentⓇ was significantly lower than those of FittydentⓇ, HexamedineⓇ, ListerineⓇ, and Apple vinegarⓇ(P<.05). In the 0.5 × 107 cfu/, the C. albicans' death rates of PolidentⓇ and CoolingdentⓇ were significantly lower than those of FittydentⓇ, HexamedineⓇ, ListerineⓇ and Apple vinegarⓇ(P<.05). The C. albicans' death rates of PolidentⓇ and CoolingdentⓇ were significantly decreased at 0.02 g and 0.01 g. The C. albicans' death rate of FittydentⓇ was significantly decreased at 0.005 g (P<.05). The C. albicans' death rate of HexamedineⓇ was significantly decreased at 1/16 dilution. The C. albicans' death rate of ListerineⓇ was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegarⓇ was decreased at 1/4 dilution (P<.05). Conclusion. As the number of C. albicans increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% C. albicans' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.

• Journal of dental hygiene science
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• v.13 no.4
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• pp.434-439
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• 2013

This study was conducted to compare the dental plaque reduction using various mouthwashes with Quantitative Light induced Fluorescence-Digital (QLF-D). A survey on 20 students was carried out. The students who were at Shingu College. Experimental group was gargled 20 ml of Listerine during 30 seconds and 15 ml of Hexamedine during 60 seconds. Control group was gargled distilled water during 30 second. The data were analyzed with t-test using SPSS 20.0 program. The ratios of control group and experimental group were reduced. Degree of ${\Delta}R30$ and ${\Delta}R70$ Listerine group was a significant difference (p>0.05). Degree of Simple Plaque Score and ${\Delta}R30$ Hexamedine group was a significant difference (p>0.05). There was no significant difference in the distilled water gargle group (p<0.05). The result of this study has the effect of two mouthwashes reduced dental plaque. The evaluation data of this study will be used in clinical application and research about QLF-D.