• Journal of Dairy Science and Biotechnology
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• v.31 no.1
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• pp.75-83
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• 2013

Mare milk is gaining importance because of its nutritional characteristics and therapeutic properties, which enable its use as part of the diet of the elderly, convalescents, and newborn infants. This review describes the functional and bioactive components of mare milk, such as proteins, carbohydrates, and lipids, and the characteristics such as acidification and released free amino acids of fermented mare milk. The protein profile of mare milk differs from that of bovine milk but is similar to that of human milk. The salt and lactose content in mare's milk is similar to that in human milk, but mare's milk has a significantly lower content of fat. Whey protein concentration is higher and casein content is much lower in mare milk than in bovine milk. These health-promoting properties indicate that mare milk and its derivatives could become valuable foods for elderly consumers in the form of probiotic beverages. Protein allergies related to and the potential industrial applications of mare milk have also been discussed in comparison with those of bovine milk. Although mare milk has diverse advantages if used as a nutritional food and has positive effects on health, further studies are required to enable its use as a complete substitute for human milk or as a health food.

• Journal of Veterinary Clinics
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• v.38 no.4
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• pp.199-203
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• 2021

A 4-year-old Thoroughbred mare was brought to the Korea Racing Authority Equine Hospital with heightened sensitivity to touch of the hindquarter, reluctance to step forward, frequent urination even during training, clitoral winking, tail swinging, tail lifting, and training difficulties due to being in constant heat. The trainer claimed that she was in heat and exhibited reduced performance. Physical and lameness examinations revealed no abnormality. Rectal palpation and transrectal ultrasonography revealed normal reproductive organs and estrus. As she exhibited typical estrous behavior without any other physical conditions, the mare was considered to express undesirable estrous behavior. An intrauterine glass ball was inserted into the mare on ovulation day. However, the estrous behaviors were reduced unsatisfactorily. Additionally, 1 mL of peanut oil was administered on the 10th day after the intrauterine device insertion. The mare returned to training and expressed no undesirable estrous behavior over 30 days after the peanut oil treatment. However, further follow-ups were not conduct as the mare was retired to a farm after a limb injury occurred during training. This is the first report of undesirable estrous behavior in a Thoroughbred mare under the rules of racing in Korea. It is recommended that equine clinicians in Korea consider peanut oil as a therapeutic agent to control mares' estrous behavior-related problems.

• Molecules and Cells
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• v.38 no.7
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• pp.630-637
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• 2015

Morus alba root extract (MARE) has been used to treat hyperglycaemic conditions in oriental medicine. Here, we studied whether MARE possesses a cytotoxic effect on neuroblastoma. To check the cytotoxicity generated by MARE was whether relatively higher against the cancer cells rather than normal cells, we chose a neuroblastoma cell line (B103) and a normal cell line (Rat-2). A CCK assay revealed that MARE ($10{\mu}g/ml$) reduced cell viability to approximately 60% compared to an untreated control in B103 cells. But in Rat-2 cells, MARE induced relatively lower cytotoxicity. To investigate the mechanisms underlying the cytotoxic effect of MARE, we used flow cytometry combined with immunoblot analyses. We found that MARE-treatment could accumulate ROS and depolarize mitochondria membrane potential of B103 cells. Further treatment with MARE in B103 cells also could damage DNA and induce apoptosis. An expression study of p-Akt also suggested that there was a reduction in cellular proliferation and transcription along with the process of apoptosis, which was further evidenced by an increase in Bax and cleaved-caspase 3 activity. Together, our findings suggest that MARE produces more cytotoxicity in cancer cells while having a relatively attenuated effect on normal cells. As such, MARE may be a safer option in cancer therapeutics, and it also shows potential for the patients with symptoms of hyperglycemia and cancer.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.99.1-99.1
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• 2014

달은 global magnetic fields가 존재하지 않으나, 달 표면에 국지적으로 자기장이 존재하며 이러한 현상의 원인은 계속 연구중이다. 달의 자기이상 현상이 나타나는 지역 중 광학적으로 밝고 어두운 패턴이 관측되는 지역을 Swirl이라한다. Mare Crisium ($17.18^{\circ}N$, $59.1^{\circ}E$)은 표면에 2개의 자기이상 지역과 광학적으로 밝은 지역들이 존재하지만, Swirl로 잘 알려진 Reiner Gamma와 같은 지역의 광학적 밝기와 패턴의 차이가 있다. 이를 위해 본 연구에서는 Lunar Prospector (LP) 위성의 magnetometer (MAG) 자료를 이용하여 자기장 분포에 관한 연구 및 Clementine 위성의 UV/VIS 영상자료를 이용하여 광학적 특성 연구를 진행하였다. LP의 MAG 자료는 Mare Cirisium지역의 22.3 km 고도에서 관측된 744개의 자료를 활용하였으며, Clementine의 영상자료는 750 nm, 950 nm의 반사도에 따른 Optical Maturity (OMAT)를 활용하였다. Mare Crisium의 북쪽지역은 자기이상 현상과 OMAT의 고유특성이 동시에 나타나며 이는 swirl과 유사하다. 특히, Mare Cirisum서쪽에 있는 Proclus crater 잔해 일부가 Mare Crisium의 북쪽지역까지 퍼져있어 이와 관련하여 자기장 존재여부에 따른 광학적 특성의 차이점을 조사하였다. 본 논문에서는 Mare Crisium 지역의 Swirl 진위여부를 추론하며, 본 논문에서 이용한 방법의 유용성에 대하여 검증하고자 한다.

• Proceedings of the KSRS Conference
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• 2007.10a
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• pp.333-336
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• 2007

SELENE, a Japanese lunar mission, has been launched this year. There are large volumes of images that were already archived and will be archived by missions such as SELENE. Automatic image analysis systems, which extract useful information from large amounts of data, are now required. The authors propose Lunar Surface GIS, which archives lunar surface information collected by lunar orbiting spacecraft and conducts geological analysis automatically. This system includes automatic crater detection, automatic age determination, and lava thickness estimation methods. In this paper, methods for automatically determining the age and estimating the lava thickness of lunar mare are described. The lunar surface age was determined by analyzing data of detected crater size and number using a crater chronology method. Lava thickness was estimated by the extent of the overlying material around the crater as well as the composition of underlying terrain units. In this result, the age map at Mare Crisium suggests the mare had been formed 3.0-3.7 b.y. ago. The lava thickness result suggests the thickest part of the mare is distributed around the center of the mare. The Lunar Surface GIS can produce a geological map, age map, and mare lava thickness map, for example.

• Journal of Animal Reproduction and Biotechnology
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• v.35 no.4
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• pp.366-369
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• 2020

Foaling is a process of giving birth to foal which is prompt and forceful event in equine breeding. Dystocia is declared when 2nd stage of parturition exceeds from 20 min without fetal movements in mare. Dystocia is very challenging situation for both mare and veterinarian. Survivability of mare and foal, and subsequent fertility of mare depends on efficient management. Therefore, the current report described a rare case of wry neck (torticollis or unilateral bent neck) resulted in dystocia, that was efficiently resolved by partial fetotomy and repulsion technique in mare under field conditions. Intensive post operative care was performed to avoid infection and to achieve fertility subsequently.

• Food Science of Animal Resources
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• v.23 no.2
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• pp.150-154
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• 2003

Mare milk has a unique composition compared to other animal milks. This study was to determine the content of vitamin A in mare milk using HPLC and compared with cow milk The RT(retention time) of vitamin A by HPLC was about 4.4 min in mare and cow milk The results showed that vitamin A content of cow milk was higher than that of mare milk in each gram of milk sample. And the vitamin A content of mare cream was lower than that of cow cream in each gram of lipid. Consequently, vitamin A content of cow milk was higher than that of mare milk.

• Food Science of Animal Resources
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• v.23 no.1
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• pp.75-79
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• 2003

This study was carried out to detect the pro-inflammatory cytokines(IL-1, IL-6, TNF-a, IL-18) and IL-1 receptor accessory in mongolia mare's milk by western blotting. IL-1 and TNF-a were detected in 4 samples of mare's milk Proteins of 6 kD and 7 kD were bound to specific antibody against hIL-18. But, IL-l and TNF-a were not detectable in Difco skim milk IL-6 like factor of 60 kD was detected in both Difco skim milk and mare's milk. Also, IL-1 receptor accessory of 55 kD was detected in the mongolia mare's milk.

• Korean Journal of Poultry Science
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• v.41 no.3
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• pp.197-204
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• 2014

The objective of this study was to evaluate the effects of different levels of red ginseng mare or Korean mistletoe powder on growth performance and physicochemical properties of thigh meat in broiler. A total of 200 broiler chicks were divided into five groups were fed a basal diet (control), basal diet supplemented with 0.5% red ginseng mare (T1), red ginseng mare 1% added (T2), Korean mistletoe 0.5% added (T3), Korean mistletoe 0.5% added (T4) for five weeks. Growth performance and proximate composition of chicken thigh meat were not influenced by all treatments, except for mortality and crude fat, which was significantly lower in all treatments with red ginseng mare or Korean mistletoe powder compared to control. Dietary red ginseng mare and Korean mistletoe supplementation had no significantly effects on pH, WHC, shear force, CIE $L^*$, $b^*$ values, triglyceride and glucose but TBARS values total cholesterol, and LDL-cholesterol were decreased (P<0.05) by the addition red ginseng mare and Korean mistletoe powder. CIE $a^*$ values increased significantly with added red ginseng mare and Korean mistletoe powder relative to the control (P<0.05). It was concluded that the addition of red ginseng mare and Korean mistletoe powder revealed minor improvements in the lipid oxidative stability of chicken meat.

• Journal of Space Technology and Applications
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• v.1 no.2
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• pp.217-240
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• 2021

Upon the human exploration era of the Moon, this paper introduces lunar topography and geologic fundamentals to space scientists. The origin of scientific terminology for the lunar topography was briefly summarized, and the extension of the current Korean terminology is suggested. Specifically, we suggest the most representative lunar topography that are useful to laymen as 1 ocean (Oceanus Procellarum), 10 maria (Mare Imbrium, Mare Serenitatis, Mare Tranuillitatis, Mare Nectaris, Mare Fecundatis, Mare Crisium, Mare Vaporium, Mare Cognitum, Mare Humorum, Mare Nubium), 6 great craters (Tyco, Copernicus, Kepler, Aristachus, Stebinus, Langrenus). We also suggest Korean terms for highland, maria, mountains, crater, rille, rima, graben, dome, lava tube, wrinkle ridge, trench, rupes, and regolith. In addition, we introduce the standard model for the lunar interior and typical rocks. According to the standard model on the basis of historical impact events, the lunar geological eras are classified as Pre-Nectarian, Nectarian, Imbrian, Erathostenesian, and Copernican in chronologic order. Finally, we summarize the latest discovery records on the water on the Moon, and introduce the concept of water extraction from the lunar soil, which is to be developed by the Korea Institute of Geoscience and Mineral Resources (KIGAM).