• Title/Summary/Keyword: Material screening

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A Study on the Utilization of Yun Chun Andalusite as a Raw Material of High Alumina Refractories (II) -On the Concentration and Purification- (고 알루미나질 내화물 원료로서 연천산 홍주석의 이용에 관한 연구(II) -홍주석의 선광 및 정제-)

  • Ahn, Young-Pil;Choi, Long
    • Journal of the Korean Ceramic Society
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    • v.11 no.1
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    • pp.23-28
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    • 1974
  • 1. Stage crushing by jaw crusher, steel mortar, and ball mill in turn has shown an inclination to increase the distribution of andalusite in coarse particles as well as to increase that of micas in fine particles. 2. Water elutriation was effective for the removal of muscovite and magnetic separation was effective for that of Mg-Fe micas such as biotte and chlorite. The process of concentration and that of purification are diagramatized respectively as follows: Concentration; Raw andalusite${\lightarrow}$Crushing${\lightarrow}$Screening${\lightarrow}$Water elutriation${\lightarrow}$Magnetic separation Purification; Concentrated andalusite${\lightarrow}$Calcination${\lightarrow}$Ball milling${\lightarrow}$Screening${\lightarrow}$Water elutriation${\lightarrow}$Magnetic separation${\lightarrow}$Acid washing.

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Isolation of the Open and Infilled Trenches for the Surface-Waves Induced by the Traffic Loads (교통하중에 의한 지반진동의 차단에 관한 연구)

  • Lee, Phil-Kyu;Kim, Moon-Kyum;Kwon, Hyung-Oh
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2000.06a
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    • pp.1900-1906
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    • 2000
  • In this study, the vibration screening effectiveness of barriers which can isolate structures from ground-transmitted vibration generated by harmonic forces is performed. For high frequencies, the vibration screening effectiveness of barriers is analyzed from field tests, and compared with the results from numerical analyses using a commercial program, ANSYS. Using these numerical analysis procedures, the effectiveness for vibration with various low frequencies is predicted. The frequency analysis tests of surface waves are performed in order to estimate the dynamic material properties of soil for 100 Hz, 150 Hz, 200 Hz, and 250 Hz. Three-dimensional solid elements are used in order to consider the diffraction of waves in all directions. Spring-damper combination elements are used in order to avoid the reflection of waves on the boundary. The results of numerical analysis agree with those of field tests. From the results of this numerical analyses, the reduction of vibration for low frequencies induced by the traffic loads can be predicted.

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Selection and Control Effect of Environmental Friendly Organic Materials for Controlling the Ginseng Alternaria Blight (인삼에 발생하는 점무늬병의 친환경적 방제를 위한 유기농업자재 선발 및 기 선발된 자재의 효과시험)

  • Kim, Woo Sik;Park, Jee Sung
    • Korean Journal of Medicinal Crop Science
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    • v.21 no.5
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    • pp.388-393
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    • 2013
  • This study was conducted to select environmental friendly organic materials for controlling the ginseng alternaria blight and to evaluate their effects from 2011 to 2012. Alternaria blight is caused by Alternaria panax and is the most common ginseng disease in Korea. Environmental friendly organic materials were used to reduce amount of chemical fungicides and the number of spray for control of Ginseng Alternaria leaf blight. In 4 years of ginseng, control value of Alternaria leaf blight by single application of Defenoconazole WP was 82.3% and those of single application was 62.0~75.9%. Consequently, mixed or alternated application of eco-material products could be recommended as a control method to reduce the amount of fungicides.

HPLC Analysis and Screening of Standard Compound on Saposhnikoviae Radix for Standardization of GCSB-5 Preparation (생약복합제 GCSB-5의 품질 표준화를 위한 방풍의 지표성분 탐색 및 HPLC 분석)

  • Cha, Bae-Cheon;Lee, Eun-Hee
    • Korean Journal of Pharmacognosy
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    • v.40 no.2
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    • pp.103-108
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    • 2009
  • GCSB-5 preparation is a purified extract from a mixture of 6 medicinal plants(Acanthopanacis Cortex, Achyranthis Radix, Saposhnikoviae Radix, Cibotii Rhizoma, Glycine Semen Nigra, Eucommiae Cortex) that have been widely used for the treatment of various bone disorders. The aim of this study was to investigate HPLC analysis method and screening of standard compound on Saposhnikoviae Radix for quality standardization of a medicinal crude drug GCSB-5. Standard compound of Saposhnikoviae Radix was decided with cimifugin by isolation and instrumental analysis such as NMR. HPLC analysis method for the simultaneous determination of cimifugin was established for the quality control of the medicinal plants of Saposhnikoviae Radix species, GCSB-5 raw material and preparation. And validation of HPLC analysis methods were conformed for verification of HPLC methods by check to specificity, linearity, intra-day precision, inter-day precision and accuracy following ICH guideline.

Biomarker-directed Targeted Therapy in Colorectal Cancer

  • John M. Carethers
    • Journal of Digestive Cancer Research
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    • v.3 no.1
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    • pp.5-10
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    • 2015
  • With advances in the understanding of the biology and genetics of colorectal cancer (CRC), diagnostic biomarkers that may predict the existence or future presence of cancer or a hereditary condition, and prognostic and treatment biomarkers that may direct the approach to therapy have been developed. Biomarkers can be ascertained and assayed from any tissue that may demonstrate the diagnostic or prognostic value, including from blood cells, epithelial cells via buccal swab, fresh or archival cancer tissue, as well as from cells shed into fecal material. For CRC, current examples of biomarkers for screening and surveillance include germline testing for suspected hereditary CRC syndromes, and stool DNA tests for screening average at-risk patients. Molecular biomarkers for CRC that may alter patient care and treatment include the presence or absence of microsatellite instability, the presence or absence of mutant KRAS, BRAF or PIK3CA, and the level of expression of 15-PGDH in the colorectal mucosa. Molecularly targeted therapies and some general therapeutic approaches rely on biomarker information. Additional novel biomarkers are on the horizon that will undoubtedly further the approach to precision or individualized medicine.

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The Evaluation of a Plastic Material Classification System using Near Field IR (NIR) Spectrum and Decision Tree based Machine Learning (Near Field IR (NIR) 스펙트럼 및 결정 트리 기반 기계학습을 이용한 플라스틱 재질 분류 시스템)

  • Kook, Joongjin
    • Journal of the Semiconductor & Display Technology
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    • v.21 no.3
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    • pp.92-97
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    • 2022
  • Plastics are classified into 7 types such as PET (PETE), HDPE, PVC, LDPE, PP, PS, and Other for separation and recycling. Recently, large corporations advocating ESG management are replacing them with bioplastics. Incineration and landfill of disposal of plastic waste are responsible for air pollution and destruction of the ecosystem. Because it is not easy to accurately classify plastic materials with the naked eye, automated system-based screening studies using various sensor technologies and AI-based software technologies have been conducted. In this paper, NIR scanning devices considering the NIR wavelength characteristics that appear differently for each plastic material and a system that can identify the type of plastic by learning the NIR spectrum data collected through it. The accuracy of plastic material identification was evaluated through a decision tree-based SVM model for multiclass classification on NIR spectral datasets for 8 types of plastic samples including biodegradable plastic.

Interaction of ${\varepsilon}-L-{\beta}-lysine$ as a Tail Analogy of Tallysomycin-A to a Double Helical DNA Oligonucletide $d(CGCTTCGAAGCG)_{2}$, was investigated by NMR

  • Lee, Chang-Jun;Won, Ho-Shik
    • Journal of the Korean Magnetic Resonance Society
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    • v.11 no.2
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    • pp.129-137
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    • 2007
  • During the screening of material which has the antimicrobial activity against aminoglycoside-resistant bacteria, A new material ${\varepsilon}-(L-{\beta}-lysine)$ polypeptide from a culture medium of Streptomyces sp.(DWGS2) was isolated, and the structure and the physicochemical properties of the new material were elucidated. The new material was separated by column chromatography of the culture medium using Dowex $1{\times}2$, Silica gel, and Sephadex LH20 etc. The structure and molecular weight were determined with the data of NMR, MALDI mass, and ESI mass experiments. And the monomer obtained by hydrolysis of the new material with 6N-HCI was identified as a $L-{\beta}-lysine(T_2)$, which is a tail of bleomycin. As tail-region analogy, $T_2({\beta}-lysine$ derivatives from streptomyces) interactions with a self-complementary oligonucleotides, $d(CGCTTCGAAGCG)_2$, was investigated by NMR.

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Screening and Purification of an Antimicrobial Peptide from the Gill of the Manila Clam Ruditapes philippinarum (바지락(Ruditapes philippinarum) 아가미로부터 항균 펩타이드의 탐색 및 정제)

  • Seo, Jung-Kil
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.2
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    • pp.137-145
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    • 2016
  • This study screened the biological activity of an acidified gill extract of the Manila clam Ruditapes philippinarum including antimicrobial, hemolytic, membrane permeabilization, and DNA-binding activity, and purified the antimicrobial material. The acidified gill extract showed potent antimicrobial activity against Bacillus subtilis and Escherichia coli without significant hemolytic activity, but showed no membrane permeabilization or DNA-binding ability. An antimicrobial material was purified from the acidified gill extract using C18 reversed-phase and cation-exchange high-performance liquid chromatography (HPLC). Treatment of the purified material with trypsin completely abolished all of the antibacterial activity against Bacillus subtilis, suggesting that the purified material is a proteinaceous antibiotic. The molecular weight of the purified material was 2571.9 Da, but no primary structural information was obtained due to N-terminal blocking. A future study should confirm the primary structure. Our results suggest that the Manila clam gill contains proteinaceous antibiotics that have a role in first-line defense. This information could be used to better understand the Manila clam innate immune system.

Spectrophotometric microtitre assay for rapid screening of membrane-disrupting herbicides (분광분석을 이용한 막과산화작용 제초제의 신속한 검정법)

  • Kwon, Ok-Kyung;Cho, Kwang-Yun;Kim, Jin-Seog
    • The Korean Journal of Pesticide Science
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    • v.4 no.1
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    • pp.11-18
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    • 2000
  • This study was conducted to establish an efficient screening method of membrane-disrupting herbicides, based on the result that membrane leakage leading to evolution of carbonyl compounds and aldehydes could be colorimetrically assessed by formation of stable chromophores with MBTH and ferric chloride. Assay conditions including plant material, light intensity, irradiation time, concentrations of reagents for colorization, and reaction time were optimized, and activities of different types of known herbicides were investigated with cucumber cotyledon discs. That result indicated that this assay was sensitive to membrane-disrupting herbicides, such as protoporphyrinogen oxidase inhibitors (acifluorfen, oxyfluorfen, oxadiazon) and an electron interceptor from photosystem I(paraquat). With seven compounds newly synthesized, highly positive correlation was observed between herbicidal activities measured by greenhouse bioassay and MBTH method. Because only a single disc(4 mm diameter) from cucumber cotyledon in 60 ${\mu}L$ of incubation solution was required to assay, a large number of herbicides could be tested simultaneously using 96-well microtitre plates. But the assay efficiency is not likely to significantly increase because of the boiling step during the reaction.

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Role of Print and Audiovisual Media in Cervical Cancer Prevention in Bangladesh

  • Nessa, Ashrafun;Hussain, Muhammad Anwar;Ur Rashid, Mohammad Harun;Akhter, Nargis;Roy, Joya Shree;Afroz, Romena
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.3131-3137
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    • 2013
  • Background: Visual inspection of cervix with acetic acid (VIA) is offered at 252 centers in 64 districts of Bangladesh. VIA+ve women are managed at colposcopy clinics of Bangabandhu Sheikh Mujib Medical University (BSMMU) and 14 Medical College Hospitals (MCHs). This research work has been supported by 'UICC Cancer Prevention Campaign' programme. Objectives: This study explored the role of print materials and electronic media to improve cervical cancer screening in the present socio-cultural context of Bangladesh. Methods: This study was performed from January to August 2011 at two upazilas of Bangladesh (Singair with screening facility and Sonargaon without screening facility). Data were collected by focus group discussion (FGD) with women, husbands and community people before and after intervention. Information on cervical cancer screening and VIA camps was disseminated using advertisement through local cable line of the television, microphone announcement, service providers and leaflet throughout the week prior to a VIA camp. Three-day VIA camps were organized at the upazila health complex (UHC) of both upazilas. Quantitative data was gathered from women at the camps on source of information on VIA and the best method of awareness creation. Results: The population was aware of "cancer" and a notable number knew about cervical cancer. Baseline awareness on prevention and VIA was low and it was negligible where screening services were unavailable. Awareness was increased fourfold in both upazilas after interventions and half of the women and the majority of the community people became aware of screening and available facilities. Cable line advertisement (25.5%), microphone announcement (21.4%), and discussion sessions (20.4%) were effective for awareness creation on VIA. Television was mentioned as the best method (37.4%) of awareness creation. Conclusion: Television should be used for nation-wide awareness creation. For local awareness creation, cable line advertisement, microphone announcements and health education at Uthan Baithaks/ EPI sessions can easily be adopted by the government.