• Title/Summary/Keyword: Mechanim

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Opioid-induced Muscle Rigidity with a Delayed Manifestation Misunderstood as a Tension Pneumothorax -A case report- (긴장성 기흉으로 오인된 지연 발현된 아편양 제제 유발 근경축 -증례보고-)

  • Kang, Bong Jin;Kim, Sung Hoon
    • The Korean Journal of Pain
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    • v.21 no.1
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    • pp.66-70
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    • 2008
  • Opioid-induced rigidity is a potentially life-threatening complication that can occur after treatment with large doses of opioids, but with early recognition it can be treated effectively with naloxone or with muscle relaxants. Regarding its onset time, there have been few case reports that have described delayed manifestations of opioid-induced rigidity. The mechanism of this complication is not well understood. In this report we describe a case of incidental overdose injection of sufentanil and subsequently review the confusing clinical features that require immediate diffenrentiation and the possible mechanim of this complication.

Development of the 5 - DOF Robot Arm Simulator using Unity3D Engine (유니티 3D를 이용한 5자유도 로봇 팔 시뮬레이터 개발)

  • Jo, Byung-hyun;Lee, Kang-Hee
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2014.07a
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    • pp.257-258
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    • 2014
  • 본 논문에서는 유니티 3D에 대해서 설명하려고 한다. 기본적인 특징, 사용 환경, 인터페이스(Interface)와 함께 다양한 기술과 함께 로봇 팔의 시뮬레이터 개발 구현까지 연구하였다. 컴퓨터 내에서와는 다르게 안드로이드, 아이폰 게임에서, 필요 없이 높은 사양을 가지고 있는 다른 프로그램들과 다르게, 최적의 제작환경을 가지고 있다. 유니티 3D에서 가능한 여러 가지 기능을 이용해서 가상 세계이지만 간단하게 실제 세계와 비슷한 상황의 로봇 팔 시뮬레이터 제작에 대해서 설명하였다.

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Salviae Radix Suppresses Mast Cell-mediated Allergic Response: Inhibition of Src-family Kinase (단삼추출물의 Src-family Kinase 억제에 의한 항앨러지 효과)

  • Kim, Young-Mi
    • YAKHAK HOEJI
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    • v.52 no.5
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    • pp.370-375
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    • 2008
  • In this study, the anti-allergic activity and mechanim of Salviae radix (SR) were investigated. The ethanol extract of SR showed significant inhibitory effect on degranulation from antigen-stimulated mast cells and it also inhibited the expression and secretion of TNF-${\alpha}$ and IL-4 in antigen-stimulated RBL-2H3 cells. In the mast cell-mediated local animal allergy model, it suppressed the passive cutaneous anaphylaxis in a dose-dependent manner. As its mechanism of action, SR inhibited the activating phosphorylation of Syk, a downstream signaling molecule of Src-family kinase, for the activation of mast cells. The results of the study indicate that the anti-allergic activity of SR is mediated by the inhibition of Src-family kinase in mast cells.

LASER CONSOLIDATION OF THE PLASMA COATED CHROME CARBIDE LAYER (레이저를 이용한 크롬카바이드 플라즈마 용사층의 특성향상)

  • An, Hui-Seok;Lee, Chang-Hui
    • Korean Journal of Materials Research
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    • v.7 no.3
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    • pp.203-212
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    • 1997
  • This paper evaluated the feasibility of laser consolidation for improving the properties of the plasma coated layer, Further, the mechanim of the degradation sequence of the chrome carbide layer applied on the turbine blades was postualted. The laser consolidation could be successfully applied for improcing the surface properties of the plasma coated blade, if a proper condition was carefully chosen. The consolidated layer had erosion & corrosion resistance and vond strength superiro to those of the as-plasma coated layer. The properties of the consolidated layer were strongly dependent upon the degree of dilution, especially on the Fe pickup from the substrate. The degradation of the plasma coating layer was thought to be a reault of the repeating action of the solid particle erosion, corrosion penetration through the pores and oxide films formed along the interlayer surface and impact spalling.

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An experimental study on the effect of deterioration of drainage system on tunnel structures (배수시스템 수리기능저하가 터널구조물에 미치는 영향에 대한 실험적 연구)

  • Kwon, Oh-Yeob;Shin, Jong-Ho;Yang, Yu-Hong;Joo, Eun-Jung
    • Proceedings of the Korean Geotechical Society Conference
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    • 2006.03a
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    • pp.970-979
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    • 2006
  • Construction of underground structure requires higher standard of planning and design specifications than in surface construction. However, high construction cost and difficult working environment limit design level and construction quality. One of the most sensitive factors to be considered are infiltration and external pore-water pressures. Development of pore-water pressure may accelerate leakage and cause deterioration of the lining. In this paper, the development of pore-water pressure and its potential effect on the linings are investigated using physical model tests. A simple physical equipment model with well-defined hydraulic boundary conditions was devised. The deterioration procedure was simulated by controlling both the permeability of filters and flowrate. Development of pore-water pressure was monitored on the lining using pore pressure measurement cells. Test results identified the mechanim of pore-water pressure development on the tunnel lining which is the effect of deterioration of drainage system. The laboratory tests were simulated using coupled numerical method, and shown that the deterioration mechanism can be reproduced using coupled numerical modelling method.

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