• Title/Summary/Keyword: Medicinal herb

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The Amelioration Effect of the Ethanolic Extract of Cnidium officinale in Mice with Imiquimod-induced Psoriasis-like Skin Lesion

  • Lee, Yong Jun;Hong, In Kee;Kim, Hill;Heo, Seong Il;Kwon, Dong-Joo;Ahn, Won Gyeong;Kim, Young Han;Seo, Eun-Jung;Han, Sang In;Cho, Hyun-Jong;Kim, Sun Young;Yang, Heejung
    • Natural Product Sciences
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    • v.24 no.1
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    • pp.21-27
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    • 2018
  • Psoriasis is an auto-immune skin disease, which is characterized by the excessive generation of plaques on the skin with typically a long-lasting red, itchy and scaly symptoms. Imiquimod, which has been used for the treatment of external genital warts, actinic keratosis, and superficial basal cell carcinoma, induced of psoriasis-like skin disorders with skin erythema and thickness in mice. In the present study, we tried to find the bioactive herbal extract against imiquimod-induced psoriasis-like skin disorder in mice. During the searching of the herbal extract with anti-psoriatic effect, the ethanolic extract of Cnidium officinale ameliorated imiquimod-induced psoriasis-like skin disorder in mice. The morphological evaluation, H&E staining and Psoriasis Area and Severity Index (PASI) score showed that ear and back thickness, and erythema induced by imiquimod were significantly reversed after the treatment of the cream of the ethanolic extract of C. officinale. The overexpressed myeloperoxidase (MPO) and keratin 6A levels were decreased by the treatment of C. officinale cream. Also, $IFN-{\gamma}$, c-fos and $I{\kappa}B-{\alpha}$ mRNA levels, which are related to the progression of psoriasis, were reduced by C. officinale cream. Thus, the ethanolic extract of C. officinale ameliorated psoriasis-like skin disorder induced by imiquimod and might be the therapeutic agent for psoriasis.

Review on History of Local Medicinal Herb Festival (한방지역축제의 역사성 고찰)

  • Song, Jae-Min;Do, Mi-ja;Ahn, Sang-Woo;Jung, Ji-Ho;Kim, Namil
    • The Journal of Korean Medical History
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    • v.28 no.2
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    • pp.1-13
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    • 2015
  • Purpose : Local medicinal herb festivals present the history of the Korean medicine and cultural resources in the regions to play an important role in attracting tourists, vitalizing local economy, and improving the local image. Therefore, it is important to understand the origin of the festival and grasp historical and cultural meaning of local medicinal herb festivals. Methods : I compared the books and articles presented in the reference list. Results & Conclusions : Local medicinal herb festivals originates from traditional yangnyeongsi. Since the $17^{th}$ century, yangnyeongsi has grown up as a special market. Implementation of the Daedong Act promoted commodity and monetary economy that helped commerce and industry develop and market grow up. It also made changes in the social status system and yangnyeongsi has been such a historical phenomenon appeared in this social background. The growth of yangnyeongsi contributed to the progress in the private medicine that triggered the gradual transfer of power in the medicine to the private sector which has long been held by the government. In yangnyeongsi, there were many cultural events to attract visitors. It's the same case in China that preserves stages that were used for cultural events in the medicine market to pass down the historic sites while those in Korea are disappearing as yangnyeongsis are being pulled out of the city areas to the suburban areas due to the redevelopment projects. For this reason, restoration of the place for traditional yangnyeongsi should be taken into account through local medicinal herb festivals.

Changes of Microorganisms and Active Compounds in Glycyrrhizae Radix as Affected by Drying Method and Gamma Ray Treatments (건조 방법 및 감마선 조사에 따른 감초의 미생물 저감효과 및 유효성분 변화)

  • Kim, Joon-Hee;Kang, Byoung-Man;Kim, Jun Yong;Kim, Ryu-Dam;Hwang, Hyun Chul;Lee, Jae-Woong
    • Korean Journal of Plant Resources
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    • v.35 no.4
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    • pp.428-434
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    • 2022
  • Glycyrrhizae Radix is an herbal medicine vulnerable to fungi. So there are regulations on mycotoxins. Therefore, in this study, the affect of various drying methods and additional gamma irradiation (10 kGy) was studied to suppress the microbial generation of Glycyrrhizae Radix. As a result of detecting and comparing microorganisms using the dry film method for samples prepared by each of natural, hot air, freezing, microwave drying and gamma irradiation, the affect of reducing microorganisms by microwave drying and gamma irradiation was confirmed. There was no statistically significant change in the content of the active compounds between the treatment groups.

The latest Situation of Medicinal Hers Culture and Improvement of Distribution Structure (최근의 약초재배 현황과 유통구조의 개선)

  • SangDeukAhn
    • Korean Journal of Plant Resources
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    • v.4 no.2
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    • pp.67-74
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    • 1991
  • Many people have a growing interest on the health result from economic improvement, various environimental pollution and stress, and unrest on the adult diseases etc.In these result, demand for the herb medicine continues to expand. Farmers of theour country have a hardship in the farm management owing to of opening and liberaliza-tion, and make strenuous efforts on the devclopment of substitute crops to overcomethese differties. Government nowadays recommends the cultivation of the economiccrops like a flowers, medicinal herbs mushroom and clean vegetables. Medicinal herbsare specially profitable among these crops because herbs are possible to culture inwaste land, disused field and slope land, and owing to need less labor and competitionthan those of other crops. The most important problem is the facts that the compli-cation of currency structure of herb medicine inflicts mucll loss to cultivators. Therefore, this study was investigated the state of herb cultivation and the facts to be imploved in currency structure of the harvested herb medicine.1 . The cultivating area and output have been gradually increased and much produc-ted in Kyoungbuk, Kangwon, Choongbuk, Cheonbuk and Cheonnam province in or-der of cultivating area 2. Collection amount of wild herb medicine is decreasig bythe reason of the varous difficulties on the collection. 3. Cultivators of medicinal herbscan make agricultural management more resonable in information exchange on theherb cultivation, purchase of seed, fertilizer, chemicals and other materials, and sell-ing of harvested herb medicine by organization of cultivator fraternity. 4 Cultivatorshave to exclude intermediary margin by the development of direct transaction andcontract cultivation with medicinal herb store, drug manufacturer, chinese meicinehospital and trading firm etc. And also, by the performing exportation with foreign consumer.

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Effect of Dietary Medicinal Herb Extract Mix and Antibiotics (Albac G150) on the Oxidative Stability of Chicken Meat (금은화, 황련, 상엽 추출물 혼합물과 항생제(Albac G150) 급여가 계육의 산화 안전성에 미치는 영향)

  • Jung, S.;Song, H.P.;Choe, J.H.;Kim, B.;Shin, M.H.;Lee, B.D.;Jo, C.
    • Korean Journal of Poultry Science
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    • v.35 no.1
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    • pp.29-37
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    • 2008
  • This study was evaluated the oxidative stability of the breast and leg meat from chicken fed extract of medicinal herb mix (Lonicera japonica Thunberg : Morus alba L. : Coptis chinensis = 48.5 : 48.5 : 3.0%) and antibiotics (Albac G150). Ross chickens were divided into three treatments: basal diet (control), basal diet with antibiotics (0.05%) and basal diet with extract of medicinal herb mix (0.3%). They were fed the experimental diets for 35 days and slaughtered. After that, the breast and leg meat samples were stored at $4^{\circ}C$ for 10 days. Total phenol content of breast meat in Ross chicken fed extract of medicinal herb mix was higher than that of antibiotics treatment and control during storage. DPPH radical scavenging activity was the highest in leg meat of Ross chicken fed extract of medicinal herb mix at 0 day. $ABTS^+$ reduction activity was higher in chicken meat fed extract of medicinal herb mix than antibiotics treatment and control. This results showed that the diet with extract of mixed medicinal herb was more effective in oxidative stability of chicken meat than basal diet and diet with antibiotics.

Study on local medicinal herbs in Bonchojeonghwa Chapter of Grass ("본초정화(本草精華)" 초부(草部) 향약명(鄕藥名)에 관(關)한 연구(硏究))

  • Lee, Deok-Ho;Eom, Dong-Myung;Kim, Hong-Kyoon
    • Korean Journal of Oriental Medicine
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    • v.11 no.1
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    • pp.1-18
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    • 2005
  • As a result of study on the names of local medicinal herbs which described in Chobu (Chapter of Grass) of Korean medical book Bonchojeonghwa, we came to the following conclusions. 1) Compared with the existing domestic medical books' local medicinal herb names, those of Donguibogam had the closest relationship with Bonchojeonghwa. Out of local medicinal herb names described in Chobu of Bonchojeonghwa, a third is only shown in Bonchojeonghwa, and another third is same as those in Donguibogam. 2) The notation of local medicinal herb names in Bonchojeonghwa is not so consistent as Donguibogam. In Bonchojeonghwa, we can see many examples of inconsistent notations over the same thing. Moreover, there are some examples, which are suspected to be an expression of dialect. 3) In spite of close similarity between the names of local medicinal herbs in Bonchojeonghwa and Donguibogam, the author of Bonchojeonghwa doesn't seem to directly refer to or quote Donguibogam, because it doesn’t make sense that the author of Bonchojeonghwa intentionally referred to regular, consistent Donguibogam in irregular, inconsistent way. 4) In spite of very low possibility of direct reference or quotation among Bonchojeonghwa, Donguibogam and Bangyakhappyon, there are many examples of common format in its notation way on local medicinal herbs, which cannot be explained only as coincidence. And it tells us that there must be another publication which had been referred to or quoted by the said three medical books. 5) From the fact that there are a lot of examples of local medicinal herb names which doesn't show palatalization, or labialization, the names of local medicinal herbs described in Bonchojeonghwa must be the expression around 17th century.

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A Review on Quality Control of Korean Medicinal Herbs Through Packaging Standardization (국내 한약재의 유통상 품질 문제점과 포장표준화를 통한 대응방안 고찰)

  • Kah, Jin-Dong;Kim, Jai-Neung;Park, Su-Il;Lee, Youn-Suk
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.13 no.2
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    • pp.43-50
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    • 2007
  • The production, distribution, and consumption of Korean medicinal herbs have increased every year because of an increase of health considerations. But there are no sufficient standardization procedures in packaging and distribution systems related to these herb products. The standardization of packaging material and dimension could be a good addition for establishing proper quality control methods for Korean medicinal herbs. Medicinal herbs deteriorate under physical, chemical and biological hazards such as oxidation, textural change under high moisture content, color change by light, sanitation problems by insect invasion and contamination. Packaging standardization with proper functional packaging materials is critical to ensure the qualities of medicinal herbs. Also, storage and distribution efficiencies can be improved by achieving packaging dimension standardization. This review summarizes recent research trends related to quality evaluation methods and major quality deterioration factors of Korean medicinal herbs. This paper also offers reviews on some of problems and challenges in current packaging and distribution systems of medicinal herb industries and briefly suggests advanced quality control methods through packaging standardization.

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Quality Characteristics of Teriyaki Sauces containing Medicinal Herb Extracts

  • Kim, Hyun-Ah;Kim, Dong-Seok;Song, Chung-Rak
    • Culinary science and hospitality research
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    • v.20 no.5
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    • pp.130-135
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    • 2014
  • This study determined the effects of addition of medicinal herb extracts (Zanthoxylum piperitum extract(TZ), Acanthopanax sessiliflorus(TA), Panax ginseng(TP), Cinnamomum lureitri Nees(TC), Angelica gigantis radix(TAG) and Crataegii fructus extract (TCF) to teriyaki sauce with regard to taste and health benefit. After adding the medicinal herb extracts to teriyaki sauce, moisture content was found to be inversely proportional to the viscosity. The sauce with Panax ginseng extract(TP) had lowest sweetness, but highest salinity. The results showed that the sauce with Korean herb extracts had lower salinity content. In terms of colour value, the sauce with Crataegii fructus extract(TCF) had much higher lightness, redness, and yellowness than sauce prepared with other herb extracts. It had the strongest acidic taste and lowest pH. Sensory evaluation test revealed that the sauce with Anthoxylum piperitum extract(TZ) was the most preferred sauce among all the sauces tested. The degree of brown color of teriyaki sauces was correlated positively with taste preference(r=.570, p<0.01) and overall preference(r=.505, p<0.01).

Properties of Cheongkukjang Prepared with Admixed Medicinal Herb Powder (생약초(표고버섯, 더덕, 어성초)를 첨가한 청국장의 특성)

  • Park, Jung-Suk;Cho, Sang-Hyeok;Na, Hwan-Sik
    • Food Science and Preservation
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    • v.17 no.3
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    • pp.343-350
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    • 2010
  • Cheongkukjang was prepared by addition of medicinal herb powder (from Lentinus edodes, Codonopsis lanceolata BENTH et HOOK, or Houttuynia cordata THUNB) to improve Cheongkukjang quality and functional properties. Redness and yellowness (measured using Hunter’s color values) increased with increasing amounts of medicinal herb powder, whereas lightness (the third Hunter's color value) and pH decreased. Crude protein and lipid levels of Cheongkukjang decreased with increasing amounts of added medicinal herb powder, whereas powder addition did not affect either the moisture or crude ash content of Cheongkukjang. The major organic acids of Cheongkukjang were lactic acid, acetic acid, succinic acid, and citric acid, and acid levels increased as the proportion of medicinal herb powder in the Cheongkukjang preparation increased. The major amino acids of Cheongkukjang were glutamic acid, aspartic acid, leucine, arginine, and lysine and the principal fatty acids were linoleic acid, oleic acid, palmitic acid, and linolenic acid. Addition of medicinal herb powder to Cheongkukjang increased both crude saponin and quercetin contents. Sensory scores of Cheongkukjang containing 2% (w/v) medicinal herb powder were optimal in terms of both quality characteristics and sensory evaluation.

Properties of Cheonggukjang Tablet Prepared with Medicinal Herb Extracts (생약초(표고버섯, 더덕, 어성초) 추출물을 첨가한 청국장환의 특성)

  • Park, Jung-Suk;Na, Hwan-Sik
    • Food Science and Preservation
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    • v.18 no.2
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    • pp.149-155
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    • 2011
  • Cheonggukjang tablet was prepared by addition of medicinal herb extracts (from Lentinus edodes, Codonopsis lanceolata, or Houttuynia cordata Thunb.) to improve its quality and functional properties. Lightness and yellowness (measured using Hunter's color values) were generally increased with increasing amount of medicinal herb extracts, whereas pH decreased. In proximate composition, the levels of crude protein, lipid and fiber levels of Cheonggukjang tablet decreased with increasing amount of added medicinal herb extracts, whereas moisture and crude ash were increased. The major amino acid of Cheonggukjang tablet were glutamic acid, aspartic acid, leucine and the principal fatty acids of Cheonggukjang tablet were linolenic acid, linoleic acid and palmitic acid, respectively. Hardness levels of Cheonggukjang tablet decreased with increasing amounts of added medicinal herb extracts. The Cheonggukjang tablet added with medicinal herb extracts increased both crude saponin and quercetin contents. Sensory score of Cheonggukjang tablet containing 20% (w/v) medicinal herb extracts were optimal in terms of both quality characteristics and sensory evaluation.