• Journal of Biomedical Engineering Research
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• v.38 no.1
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• pp.1-8
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• 2017

The successful synthesis of hyaluronic acid micro-threads is very promising approach for the broad application in tissue engineering such as dermal fillers. Because hyaluronic acid has the excellent biocompatibility and ability to maintain the moisture of up to several hundred times its own weight. In order to generate the hyaluronic acid micro-threads in microfluidic system, we employed two-phase flow microfluidic chip to make a rapid synthesis of the hyaluronic acid hydrogel. Hyaluronic acid was mixed with 0.02N NaOH solution and 1, 4-Butanediol diglycidyl ether (BDDE) solution and then injected into core channel. The ethanol was used for the 3-dimensional micro-thread formation in sheath channel. We manipulated the diameter of HA micro-threads using controlling of flow rates in microfluidic chip, and showed the feasibility of immobilization in HA micro-threads with florescent substances. Also, the generated HA micro-threads were evaluated and showed the suitable properties with tensile strength, bending property, and swelling profiles for dermal fillers. As a result, we suggested an innovative method for microfluidic chip-based HA micro-threads which could safely be applied as dermal filler in tissue engineering.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.44 no.2
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• pp.59-65
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• 2018

Objectives: This study aimed to optimize the thread depth and pitch of a recently designed dental implant to provide uniform stress distribution by means of a response surface optimization method available in finite element (FE) software. The sensitivity of simulation to different mechanical parameters was also evaluated. Materials and Methods: A three-dimensional model of a tapered dental implant with micro-threads in the upper area and V-shaped threads in the rest of the body was modeled and analyzed using finite element analysis (FEA). An axial load of 100 N was applied to the top of the implants. The model was optimized for thread depth and pitch to determine the optimal stress distribution. In this analysis, micro-threads had 0.25 to 0.3 mm depth and 0.27 to 0.33 mm pitch, and V-shaped threads had 0.405 to 0.495 mm depth and 0.66 to 0.8 mm pitch. Results: The optimized depth and pitch were 0.307 and 0.286 mm for micro-threads and 0.405 and 0.808 mm for V-shaped threads, respectively. In this design, the most effective parameters on stress distribution were the depth and pitch of the micro-threads based on sensitivity analysis results. Conclusion: Based on the results of this study, the optimal implant design has micro-threads with 0.307 and 0.286 mm depth and pitch, respectively, in the upper area and V-shaped threads with 0.405 and 0.808 mm depth and pitch in the rest of the body. These results indicate that micro-thread parameters have a greater effect on stress and strain values.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.3 s.168
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• pp.179-186
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• 2005

A comparative study of stress distributions in the maxillary bone with three different types of abutment was conducted. Finite element analysis was adopted to determine stress generated in the bone with the different implant systems with micro threads (Onebody type implant, Internal type implant, and External type implant). It was found that the types of abutments and the number of micro threads have significant influence on the stress distribution in the maxillary bone. They were due to the difference in the load transfer mechanism and the size of contact area between abutment and fixture. Also the maximum effective stress in the maxillary bone was increased with increasing inclination angle of load. It was concluded that the maximum effective stress in the bone was the lowest by the internal implant among the maximum effective stresses by other two types of implants and by appropriate number of micro threads, and that the specific number of micro thread was existed to decrease the maximum effective stress in the maxillary bone due to different implant systems and loading conditions.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.11a
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• pp.933-934
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• 2010

• Journal of Dental Rehabilitation and Applied Science
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• v.24 no.1
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• pp.67-76
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• 2008

Implant requires long lasting, strong osseointegration using bio-mechanical interlocking by bone ingrowth. In regarding the size level for bone ingrowth, the micro-patterning would enhance bone response. Micro-patterning can increase the area contacting the bone tissues. Therefore, it may distribute the load to the surrounding bone tissue, more effectively. This study compared and analyzed the load distributing effect with the shape and number of micro-patterning. For the optimal comparison of threads, the assumptions different from general finite element analysis model were made. It was assumed that the implant was axisymmetric and infinitely long. The implant was assumed to be completely embedded in the infinitely long cortical bone and to have 100% bone apposition. The implant-bone interface had completely fixed boundary conditions and received an infinitely big axial load. The condition of threads were as follows. The reference model 1 had conventional thread. Model 2 had 2 micro-patterns on the upper flank of the thread. Model 3 had 2 micro-patterns on the lower flank of the thread. Model 4 had 2 micro-patterns on the upper and lower flanks of the thread. Model 5 had 3 micro patterns on the upper and lower flanks of the thread. The results were as follows: 1. The thread with micro-patterns distributed stress better than the conventional thread. 2. The thread with micro-patterns on the lower flank distributed stress better than that with micro-patterns on the upper flank. 3. The thread with 3 micro-patterns distributed stress better than that with 2 micro-patterns, However, an area with stress concentration occurred.

• Journal of Information Processing Systems
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• v.8 no.2
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• pp.331-346
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• 2012

Task-based programming is becoming the state-of-the-art method of choice for extracting the desired performance from multi-core chips. It expresses a program in terms of lightweight logical tasks rather than heavyweight threads. Intel Threading Building Blocks (TBB) is a task-based parallel programming paradigm for multi-core processors. The performance gain of this paradigm depends to a great extent on the efficiency of its parallel constructs. The parallel overheads incurred by parallel constructs determine the ability for creating large-scale parallel programs, especially in the case of fine-grain parallelism. This paper presents a study of TBB parallelization overheads. For this purpose, a TBB micro-benchmarks suite called TBBench has been developed. We use TBBench to evaluate the parallelization overheads of TBB on different multi-core machines and different compilers. We report in detail in this paper on the relative overheads and analyze the running results.

• Transactions of Materials Processing
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• v.21 no.3
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• pp.179-185
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• 2012

In this paper, it is proposed to produce high precision screws with a diameter of $800{\mu}m$ and a thread pitch of $200{\mu}m$ ($M0.8{\times}P0.2$) by means of a cold thread rolling process. In this part II of the study, the focus is on the production and reliability testing of the prototype $M0.8{\times}P0.2$ micro-screw. Designs for two flat dies were developed with the aid of the literature and previous studies. Process parameters during the cold thread rolling process were established through FE simulations. The simulation results showed that the threads of the micro-screw are completely formed through the rolling process. Prototype $M0.8{\times}P0.2$ micro-screw were fabricated with a high precision thread rolling machine. In order to verify the simulation results, the deformed shape and dimensions obtained from the experiment were compared with those from the simulations. Hardness and failure torque of the fabricated micro-screw were also measured. The values obtained indicate that the CAE based process design used in this paper is very appropriate for the thread rolling of micro-sized screws.

• Journal of Advanced Marine Engineering and Technology
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• v.27 no.3
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• pp.447-452
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• 2003

Crevice corrosion is localized form of corrosion usually associated with a stagnant solution on the micro-environmental level. Such stagnant micro environments tend to occur in crevices (shielded areas) such as those formed under gaskets washers insulation material. fastener heads. surface deposits. disbonded coatings. threads. lap joints and clamps. Crevice corrosion is initiated by changes in located electrochemical reaction within the crevice such as a) depletion of inhibitor in the crevice b) depletion of oxygen in the crevice c) a shift to acid conditions in the crevice and d) build-up of aggressive ion species (e.g chloride) in the crevice. In this study. the mechanism of crevice corrosion for Type 430 stainless steel is investigated undercondition that the size of specimen is $15{\times}20\{times}3mm$, in 1N $H_2SO_4$ + 0.05N NaCl solution. and the artificial crevice gap size of 3 x 0.2 x 15 mm. Crevice corrosion is measured under applied potential -300mV(SCE) to the external surface. The obtained result of this study showed that 1) the induced time for initiation of crevice is 750 seconds. 2) potential of the crevice was about from -320mV to -399mV. which is lower than that of external surface potential of -300mV It is considered that potential drop in the crevice is one of mechanisms for the crevice corrosion

• Journal of Korea Multimedia Society
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• v.18 no.4
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• pp.473-482
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• 2015

Doppler weather radar is an important tool for meteorological research. Through several decades of development, Doppler weather radar has enormous progress in understanding, detection and warning of meso and micro scale weather system. It makes a significant contribution to weather forecast and weather disaster warning. But the large amount of data process limits the application of Doppler weather radar. This paper proposed for fast weather radar data processing based on CUDA. CDUA is a powerful platform for highly parallel programming developed by NVIDIA. Through running plenty of threads, radar data can be calculated at same time. In experiment, CUDA parallel program can significantly improve weather data processing time.

• The korean journal of orthodontics
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• v.32 no.2 s.91
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• pp.107-115
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• 2002

The aim of this study was to investigate experimentally the mechanical and histological effect of drilling process on the stability of micro-implant used for the orthodontic anchorage. For this purpose, 32 micro-implants(Osas$^{(R)}$, Epoch medical, ${\phi}$1.6 mm) were inserted into maxilla, mandible and palate in two beagle dogs. 16 micro-implants(8 per dog) were inserted after drilling with pilot drilling bur (drill method group). 16 micro-implants(8 per dog) were inserted without drilling (drill-free method group). After 1 week, micro-implants were loaded by means of Ni-Ti coil spring (Ni-Ti springs-extension$^{(R)}$, Ormco) with 200-300 gm force. Following 12 weeks, the micro-implants and the surrounding bone were removed. Before sacrifice, the mobilities were tested with Periotest$^{(R)}$(Siemens). Undecalcified serial sections with the long axis were made and the histologic evaluations were done. The results of this study were as follow ; 1. The osseointegration was found in both of drill-free method group and drill method group 2. Two of drill method group and one of drill-free method group in 32 micro-implants were lost after loading. 3. The mobilities of drill-free method group were less than drill method group 4. The bone contact on surface of micro-implants in drill-free method group was more than drill method group but there was no significant difference between groups. 5. The bone density in threads of micro-implants in drill-free method group was more than drill method group and there was significant difference between groups. These results suggest that drill-free method in insertion of micro-implants is superior to drill method on the stabilities, bone remodeling and osseointegrations under early loading.