• Title/Summary/Keyword: Microfiltration

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Large Scale Purification of KRF-001 on the Preparative HPLC (Preparative HPLC를 이용한 KRF-001의 대량분리정제)

  • 이항우;김무경정태숙복성해
    • KSBB Journal
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    • v.9 no.4
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    • pp.385-394
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    • 1994
  • Large scale purification to get antifungal antibiotic KRF-001 of 90% purity, was investigated using preparative HPLC. Crude KRF-001 was purified by XAD-7 adsorption chromatography, acid precipitation and microfiltration. Microfiltration was the most effective isolation method of crude KRF-001. The purification methods using C18 chromatography was convenient compared with the conventional methods. Delta PAK C18 column and Bonda PAK C18 column were adapted large scale purification of KRF-001. Gradient system of prep HPLC using Delta PAK C18 column was more effective. With these conditions, final recovery of KRF-001 yielded 77%.

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Advanced Water Treatment of High Turbidity Source by Hybrid Process of Photocatalyst and Ceramic Microfiltration: Effect of Water Back-flushing Period (광촉매 및 세라믹 정밀여과 혼성공정에 의한 고탁도 원수의 고도정수처리: 물역세척 주기의 영향)

  • Park, Jin Yong;Park, Sung Woo
    • Membrane Journal
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    • v.22 no.4
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    • pp.243-250
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    • 2012
  • The effect of water back-flushing period (filtration time, FT) was investigated in hybrid process of alumina microfiltration and photocatalyst for advanced drinking water treatment in this study, and compared with the previous studies with carbon microfiltration or alumina ultrafiltration membranes. The FT was changed in the range of 2~10 min with fixed 10 sec of BT. Then, the FT effects on resistance of membrane fouling ($R_f$), permeate flux (J) and total permeate volume ($V_T$) were observed during total filtration time of 180 min. As decreasing FT, $R_f$ decreased and J increased as decreasing FT, which was same with the previous results with carbon microfiltration or alumina ultrafiltration membranes. The treatment efficiency of turbidity was high beyond 98.1%, and the effect of FT was not shown on treatment efficiency of turbidity, which was same with the previous result of carbon microfiltration. The treatment efficiency of organic matters was the highest value of 89.6 % at FT 8 min, which was a little higher than those of the previous results, and the effect of FT was not shown on treatment efficiency of organic matters.

Study on Selection of Water Treatment Filtration System to Cope with Climate Change (기후변화 대응을 위한 수처리 여과시스템 선정 방안 연구)

  • Hwang, Yun-Bin;Park, Ki-Hak
    • Journal of Climate Change Research
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    • v.9 no.1
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    • pp.75-80
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    • 2018
  • The problem of water shortages and water related disasters caused by climate change has increased the seriousness of water problems and the importance of water treatment technology capable of securing clean water is expanding. In this study, we analyzed not only the water pollutant generated by the filtration system technology of various water treatment technologies but also the indirect greenhouse gas emissions generation, and analyzed the influence on the environment. The subjects of study are Fabric Filter, Reverse Osmosis System and Pressurized Microfiltration Device which are widely used for water treatment and we analyzed the impact on the environment using the Life Cycle Assessment (LCA) method using the electricity amount necessary for use, the water purification efficiency, the throughput per ton and the cost. The amount of greenhouse gas generated when the Pressurized Microfiltration Device operates for 1 year is $2.15E+04kg\;CO_2-eq$., Fabric Filter is $3.29E+04kg\;CO_2-eq$., and Reverse Osmosis System is $1.68E+05kg\;CO_2-eq$. As a result of analyzing the amount of greenhouse gas generated at the time of purifying 1 ton of the Pressurized Microfiltration Device and the conventional filtration system, the Pressurized Microfiltration Device was $20.5g\;CO_2-eq$., Fabric Filter was $34.7g\;CO_2-eq$., and Reverse Osmosis System was $191.7g\;CO_2-eq$. The amount of greenhouse gas generated was calculated to be 41.0% less than that of the Fabric Filter by the Pressurized Microfiltration Device and 89.3% less than the Reverse Osmosis System. From the viewpoint of climate change, it is necessary to select a filtration system that takes climate change into account, not from the viewpoint of water quality removal efficiency and economic efficiency according to future water treatment applications, and it is necessary to select a water treatment filtration system more researches and improvements will be made for.

Evaluation of Microbes through Microfiltration within the Water Treatment Processes (정밀여과막 및 입상활성탄을 이용한 수처리 공정에 따른 박테리아 거동 평가)

  • Shim, Moon Jung;Lim, Jae Won;Kim, Tae Ue
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.3
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    • pp.230-236
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    • 2016
  • Economic growth has increased the living standards around the world. Water pollution, in particular, is a public relations issue because it poses a direct threat to everyone's lives. As of recently, the production of taste and odor (T&O) compounds has been a common problem in the water industry. The adsorption process using granular activated carbon (GAC) has been the most widely used process. The objectives of this study were to evaluate the microorganisms before and after the backwashing of GAC and to identify the species of the microorganisms found. Five dominants microorganisms were confirmed after the microfiltration process from backwashing of GAC, and the dominant bacterial species were found to be ${\beta}$-proteobacterium species, Porphyrobacter donghaensis, Polaromonas rhizophaerae, Hydrogenophaga species, and Pseudonocardia species. However, when UV treatment after microfiltration was performed, Hydrogenophaga species and Psedonocardia species were eliminated. Herein, I conclude that the UV treatment post microfiltration process is more efficient than microfiltration process alone. The findings of this study may provide useful information regarding the management of microfiltration process.

Characteristics of Crossflow Electro-microfiltration Process for Treatment of Oily Waste Water (오일함유 폐수 처리를 위한 전기정밀여과 공정 특성)

  • 최왕규;이재원;이근우
    • Membrane Journal
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    • v.12 no.4
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    • pp.216-225
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    • 2002
  • Experimental study on the crossflow electro-microfi1tation of simulated oil emulsion waste water was carried out with polypropylene microfiltration membrane to evaluate the applicability of electrofiltration process in the treatment of oily waste water generated from many industries including nuclear field. The effects of electric field strength transmembrane pressure, crossflow velocity, and oil emulsion concentration on the permeate flux were investigated. In electro-microfiltration process using the external electric field, significant enhancement of permeate flux was achieved by diminishing membrane fouling and it was shown that considerable permeate flux can be maintained for long-term operation compared with conventional membrane filtration process without an electric field.

Application of tube-type ceramic microfiltration membrane for post-treatment of effluent from biological wastewater treatment process using phase separation

  • Son, Dong-Jin;Kim, Woo-Yeol;Yun, Chan-Young;Kim, Dae-Gun;Chang, Duk;Sunwoo, Young;Hong, Ki-Ho
    • Environmental Engineering Research
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    • v.22 no.4
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    • pp.377-383
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    • 2017
  • A tube-type ceramic membrane for microfiltration was developed, and the membrane module comprised of three membranes was also applied to biological carbon and nitrogen removal processes for post-treatment. Manufacturing the microfiltration membrane was successful with the structure and boundary of the coated and support layers within the membrane module clearly observable. Total kjeldahl nitrogen removal from effluent was additionally achieved through the elimination of solids containing organic nitrogen by use of the ceramic membrane module. Removal of suspended solids and colloidal substances were noticeably improved after membrane filtration, and the filtration function of the ceramic membrane could also easily be recovered by physical cleaning. By using the ceramic membrane module, the system showed average removals of organics, nitrogen, and solids up to 98%, 80% and 99.9%, respectively. Thus, this microfiltration system appears to be an alternative and flexible option for existing biological nutrient removal processes suffering from poor settling performance due to the use of a clarifier.

Wastewater treatment using a hybrid process coupling adsorption on marl and microfiltration

  • Maimoun, Bakhta;Djafer, Abderrahmane;Djafer, Lahcene;Marin-Ayral, Rose-Marie;Ayral, Andre
    • Membrane and Water Treatment
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    • v.11 no.4
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    • pp.275-282
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    • 2020
  • Hranfa's marl, a local natural mineral, is selected for the decontamination by adsorption of aqueous effluents in textile industry. Its physicochemical characterization is first performed. It is composed mainly of Calcite, Quartz, Ankerite and Muscovite. Its specific surface area is 40 ㎡ g-1. Its adsorption performance is then tested in batch conditions using an industrial organic dye, Bemacid Red E-TL, as a model pollutant. The measured adsorption capacity of Hranfa's marl is 16 mg g-1 which is comparable to that of other types of natural adsorbents. A hybrid process is tested coupling adsorption of the dye on marl in suspension and microfiltration. An adsorption reactor is inserted into the circulation loop of a microfiltration pilot using ceramic membranes. This makes possible a continuous extraction of the treated water provided that a periodic replacement of the saturated adsorbent is done. The breakthrough curve obtained by analyzing the dye concentration in the permeate is close to the ideal one considering that no dye will cross the membrane as long as the adsorbent load is not saturated. These first experimental data provide proof of concept for such a hybrid process.

Direct and Indirect Membrane Integrity Tests for Monitoring Microbial Removal by Microfiltration (정밀여과(MF)막 미생물 제거율 모니터링을 위한 막 완전성시험)

  • Hong, Seungkwan;Miller, Frank;Taylor, James
    • Journal of Korean Society of Water and Wastewater
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    • v.18 no.6
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    • pp.801-806
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    • 2004
  • The pilot study was conducted to (i) investigate the ability of various membrane integrity monitoring methods to detect changes in membrane integrity during operation, and (ii) determine the impact of membrane damage on microbial removal by microfiltration. Two variations of air pressure hold tests were investigated for direct integrity monitoring: pressure decay (PD) and diffusive air flow (DAF) tests which are most commonly used integrity tests for microfiltration (MF) membranes. Both PD and DAF tests were sensitive enough to detect one damaged fiber out of 66,000 under field operaing conditions. Indirect integrity monitoring such as turbidity and particle counting, however, responded poorly to defects in membrane systems. Microbial challenge study was performed using both new and deliberately damaged membranes, as well as varying the state of fouling of the membrane. This study demonstrated that MF membrane with nominal pore size $0.2{\mu}m$ was capable of removing various pathogens including coliform, spore, and cryptosporidium, at the level required by drinking water regulations, even when high operating pressures were applied. A sharp decrease in average log reduction value (LRV) was observed when one fiber was damaged, emphasizing the importance of membrane integrity in control of microbial contamination.

Semibatch Ethanol Production from Starch by Simultaneous Saccharification and Fermentation Using Cell Recycle (균체재순환 및 동시당화발효에 의한 전분으로 부터의 반회분식 에탄올 발효)

  • 김철호;유연우김철이상기
    • KSBB Journal
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    • v.5 no.4
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    • pp.335-339
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    • 1990
  • In order to develop economic processes for ethanol production from starch, a simultaneous saccharification and fermentation(SSF) process using Zymomonas mobilis and amyloglucosidase (AMG) was studied in semibatch modes using cell recycle. The cell recycle was carried out by adopting two different methods; microfiltration and settling. The cell recycle using microfiltration revealed higher productivity(5.4 g/l/h) than that using a settler(4.3 g/l/h). Taking the large-scale ethanol fermentation into account, the semibatch process using microfiltration system appeared most promising among others with respect to ethanol productivity, feasibility of scale-up and simplification of operation.

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Preparation and Characterization of Microfiltration Membrane by Metal Particles (금속입자를 이용한 정밀여과막 제조와 특성평가)

  • Kim, In-Chul;Lee, Kew-Ho;Park, Joo-Young;Jeong, Bo-Reum;Kwon, Ja-Young
    • Membrane Journal
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    • v.17 no.4
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    • pp.381-386
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    • 2007
  • Hollow fibers were made using the nickel slurry containing nickel particles and polymers by phase inversion method. And then, metallic filters were fabricated by sintering method at $1,150^{\circ}C$ under reduction condition. Metallic microfiltration membranes were prepared by coating nickel particles on the metallic filter. The properties of the metallic hollow fiber filters and microfiltration membranes such as pore size and strength were investigated. The metallic membrane showed good resistance against acid, base and chlorine. It was observed that the membrane exhibited good recovery rate by back washing.