• Title, Summary, Keyword: Middle ear disease

Search Result 27, Processing Time 0.048 seconds

Malondialdehyde Levels in Middle Ear Fluid from Patients of Otitis Media with Effusion

  • Mun, Kyo-Cheol;Kim, Deok-Jun
    • BMB Reports
    • /
    • v.32 no.1
    • /
    • pp.25-27
    • /
    • 1999
  • Otitis media with effusion (OME) is an inflammatory disease of the middle ear cleft. Oxygen free radicals have been implicated in a variety of inflammatory disorders. Oxygen free radicals may also be involved in the pathogenesis of OME. To evaluate the involvement of oxygen free radicals in the pathogenesis of OME, the level of malondialdehyde, which gives an index of lipid peroxidation by oxygen free radicals, was measured by the reaction with thiobarbituric acid. Malondialdehyde level in the middle ear fluid from the OME group was higher than that in the normal control group. Malondialdehyde level in the middle ear fluid from a mucoid subgroup was higher than that in the serous subgroup. Malondialdehyde levels in the middle ear fluid from the serous subgroup was significantly correlated with symptom duration. The Pearson correlation coefficient between malondialdehyde levels in the middle ear fluid from the serous subgroup and symptom duration was 0.842 (P<0.05). These results indicate that lipid peroxidation by oxygen free radicals may be involved in the pathogenesis of human OME.

  • PDF

A Study on the Development of a Human Middle Ear Implant (인체 중이 임플란트 개발에 관한 연구)

  • Yoo, Seung-Hyun;Kim, Hak-Kyun;Kim, Jong-Bum;Song, Joon-Ho;Oh, Dae-Jin
    • Korean Journal of Computational Design and Engineering
    • /
    • v.14 no.2
    • /
    • pp.87-95
    • /
    • 2009
  • This paper describes the design of the ossicular replacement prosthesis for the people who have problem of hearing because of middle ear disease. Also the simulation results of the designed product for verification by finite element analysis software (ABAQUS) are presented. New model is applied to middle ear FE analysis which was generated in previous study. The full replacements of ossicular prosthesis for ossicles (malleus, incus and stapes) are made of Hydroxyapatite and Titanium. Although other existing prosthesis models consider only sound amplification effect, current type has damper system which is operating on the audible frequencies. High frequency sound transmitted to inner ear can be reduced and the prosthesis and inner ear can be prevented from damage.

Middle Ear Disease Decision Scheme using HOG Descriptor (HOG 기술자를 이용한 중이염 자동 판별 방법)

  • Jung, Na-ra;Song, Jae-wook;Kang, Hyun-soo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • /
    • pp.693-694
    • /
    • 2015
  • This paper present a decision method of middle ear disease which is developed in children and adults. In the proposed method, features are extracted from the middle ear disease images and normal images using HOG(histogram of oriented gradient) descriptor and the extracted features are learned by SVM(support vector machine) classifier. Input images are classified by SVM classifier based on the model of learning features. Experimental results show that the method yields accuracy of over 90% in decision.

  • PDF

Modeling and Analysis of Eardrum using FEM (고막의 유한요소 모델링 및 해석)

  • 강희용;김봉철;이동헌;임재중;전병훈
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
    • /
    • /
    • pp.495-499
    • /
    • 2000
  • Auditory system is separated to Outer Ear, Middle Ear and Inner Ear, Middle Ear plays an important role as the sound transfer on amplitude. With analysing of Middle Ear, we can understand disease and compare unformal auditory systems. However, the investigation of mechanical modeling and analysis have been reported in a few paper. In this paper, a three dimensional Eardrum model of human ear was developed and analysed applying the general purpose Finite-Element program (Nastran). Vibration patterns of the eardrum obtained from FEM analysis are in agreements with the experimental results using stroboscope.

  • PDF

Middle Ear Disease Automatic Decision Scheme using HoG Descriptor (HoG 기술자를 이용한 중이염 자동 판별 방법)

  • Jung, Na-ra;Song, Jae-wook;Choi, Ho-Hyoung;Kang, Hyun-soo
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.20 no.3
    • /
    • pp.621-629
    • /
    • 2016
  • This paper presents a decision method of middle ear disease which is developed in children and adults. In the proposed method, features are extracted from the middle ear disease images and normal images using HoG (histogram of oriented gradient) descriptor and the extracted features are learned by SVM (support vector machine) classifier. To obtain an input vector into SVM, an input image is resized to a predefined size and then the resized image is partitioned into 16 blocks each of which is partitioned into 4 sub-blocks (namely cell). Finally, the feature vector with 576 components is given by using HoG with 9 bins and it is used as SVM learning and classification. Input images are classified by SVM classifier based on the model of learning features. Experimental results show that the proposed method yields the precision of over 90% in decision.

Tumor Stage-Related Role of Radiotherapy in Patients with an External Auditory Canal and Middle Ear Carcinoma

  • Choi, Jinhyun;Kim, Se-Heon;Koh, Yoon Woo;Choi, Eun Chang;Lee, Chang Geol;Keum, Ki Chang
    • Cancer Research and Treatment
    • /
    • v.49 no.1
    • /
    • pp.178-184
    • /
    • 2017
  • Purpose The purpose of this study was to evaluate the clinical outcomes of patients treated with radiotherapy (RT) for a carcinoma of the external auditory canal (EAC) and middle ear. Materials and Methods The records of 32 patients who received RT from 1990 to 2013 were reviewed retrospectively. The Pittsburgh classification was used to stage all the cancers (early stage, T1/T2 [n=12]; advanced stage, T3/T4 or N positive [n=20]). Twenty-one patients (65.6%) were treated with postoperative RT and 11 patients (34.4%) were treated with definitive RT. The median radiation doses for postoperative and definitive RT were 60 Gy and 64.8 Gy, respectively. Chemotherapy was administered to seven patients (21.9%). Results The 5-year overall survival and disease-free survival rates for all patients were 57% and 52%, respectively. The disease control rates for the patients with early stage versus advanced stage carcinoma were 55.6% (5/9) and 50% (6/12) in the postoperative RT group and 66.7% (2/3) and 37.5% (3/8) in the definitive RT group, respectively. Overall, 15 cases (14 patients, 46.7%) experienced treatment failure; these failures were classified as local in four cases, regional in one case, and distant in 10 cases. The median follow-up period after RT was 51 months (range, 7 to 286 months). Conclusion Patients with early stage carcinoma achieved better outcomes when definitive RT was used. Advanced stage carcinoma patients experienced better outcomes with postoperative RT. The high rate of distant failure after RT, with or without surgery, reflected the lack of a consensus regarding the best therapeutic approach for treating carcinoma of the EAC and middle ear.

RECENT TRENDS IN INCIDENCE AND MANAGEMENT OF CLEFT LIP AND PALATE (구순열과 구개열의 발생요인 및 치료 경향)

  • Yoon, Chun-Ju;Ryu, Sun-Youl
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.28 no.4
    • /
    • pp.295-309
    • /
    • 2006
  • The present study was aimed to evaluate the incidence, etiological factors, and management of cleft lip and palate. Two hundred and twenty patients with cleft lip and/or cleft palate who were treated at Department of Oral and Maxillofacial Surgery, Chonnam National University Hospital, during the period between January 1994 and December 2003 were reviewed. The ratios of cleft lip : cleft lip with cleft palate : and cleft palate were 0.4:1.1:1. Males were more common than females in cleft lip (1.3:1) and cleft lip and palate (2.5:1), while females were more common than males in cleft palate (1:1.3). In the cleft side, left clefts were more prevalent than right clefts (cleft lip 1.3:1, cleft lip and palate 1.6:1). Unilateral clefts were more common than bilateral clefts in cleft lip (79:21). Cleft lip and cleft palate were more common in those with blood type A (34.5%) than those with other types. There was no significant relationship between birth season and frequency of clefts. The clefts were common in the first-born (48.8%), and in mothers aged between 25 and 29 (51.7%). Medication (24.7%) and stress (16.7%) during the first trimester were noted. Positive familial history was noted in 13 cases (5.9%). Thirty-two cases (15%) were associated with other congenital anomalies, in which tonguetie (40.6%) and congenital heart disease (21.9%) were most common. Among 100 patients with cleft palate, 77 patients had middle ear disease (77%), which occurred predominently in the incomplete cleft palate. Seventy-six among the 77 patients received myringotomy and ventilation tube insertion, and the remaining one received antibiotic medication only. Cleft lips were treated primarily at 3 to 6 months, and cleft palates were at 1 to 2 years. Treatment regimens included modified Millard method mainly in the cleft lip, and Wardill V-Y, Dorrance method, and Furlow method in the cleft palate. The percentage of palatal lengthening as type of cleft palate was greater in the incomplete cleft palate group (11.2%) than in the complete cleft palate group (9.6%). The percentage of palatal lengthening as operating method was no difference between the Furlow method (10.9%) and the push back method (10.7%). As postoperative complications, hypertrophic scar was most frequent in the cleft lip, and oronasal fistula in the cleft palate. In summary, it was shown that medication and stress during the first trimester of pregnancy were frequently associated with cleft lip and cleft palate, adequate timing and selection of method of operation are important factors to obtain morphologically and functionally good results. Furthermore prevention and treatment of middle ear disease are important in cleft palate patients because of its high co-occurrence.

The Effects of Auricular Acupressure Therapy on Middle-aged and Old Adults' Dry Eye Syndrome (이압요법이 중·노년의 안구건조증에 미치는 효과)

  • Choi, Yun-Joo;Hwang, Sun-Kyung;Kim, Sang-Sik
    • Journal of East-West Nursing Research
    • /
    • v.26 no.1
    • /
    • pp.17-27
    • /
    • 2020
  • Purpose: This study aimed to examine the effect of auricular acupressure therapy on reducing the ocular symptoms and signs for dry eye syndrome. Methods: The participants who were aged ≥ 40 years old and met the inclusion criteria of the ocular surface disease index score ≥ 13 and a tear film break-up time ≤ 10 seconds were enrolled into the two groups: experimental group (n=29) and control group (n=27). Experimental group received auricular acupressure therapy for 8 weeks. Seed stickers were applied to the eye, liver and tubercle point of each ear once a week. Data were collected at pre and 4 and 8 weeks after the treatment and analysed the efficacy of intervention by repeated measures ANOVA. Results: There were significant differences in the ocular surface disease index, standard patient evaluation of eye dryness and a tear film break-up time in both eyes at 8 weeks after the treatment between the two groups. Conclusion: The findings indicate that the auricular acupressure therapy may be helpful for relieving symptoms of dry eye as a nursing intervention. In addition, it could also be utilized as a self-care practice using proper education and training.

A Case of Cholesterol Granuloma of Maxillary Sinus Misdiagnosed as Odontogenic Cyst (치성낭종으로 오인된 상악동 콜레스테롤 육아종의 1례)

  • Han, Byung Hyun;Choi, Ick Soo
    • Journal of Rhinology
    • /
    • v.25 no.2
    • /
    • pp.108-113
    • /
    • 2018
  • Cholesterol granuloma is a disease in which cholesterol crystals act as a foreign substance in the surrounding tissues and cause granulomatous reaction and fibrosis within the chamber. It is found in various locations of the body, but the most common location is the temporal bone associated with middle ear disease. Because the disease is associated with breathing disturbance, it may also occur in the paranasal sinus. However, it has been rarely reported since its first report by Graham and Michaels in 1978. Recently, we experienced a case of cholesterol granuloma of the right maxillary sinus of a 63-year-old female patient without any nasal symptoms. We successfully managed this case with Caldwell-Luc operation. Also, we summarized the cases of cholesterol granuloma of the sinonasal region reported in Korea.

Treatment of Otitis Media in Cleft Palate (구개열 환자에 있어 중이염의 치료)

  • Pang, Kang-Mi;Ji, Young-Min;Kim, Seong-Min;Myoung, Hoon;Choi, Jin-Young;Lee, Jong-Ho;Choung, Pil-Hoon;Kim, Myung-Jin;Hwang, Soon-Jung
    • Korean Journal of Cleft Lip And Palate
    • /
    • v.10 no.2
    • /
    • pp.89-96
    • /
    • 2007
  • Otitis media with effusion is known to be very common among children with cleft palate and is the common cause of acquired hearing loss in childhood. The purpose of the present study was to examine the anatomic variances, incidence and treatment of middle ear disease in children with cleft palate. In Korea, before 4-year-old age, the prevalence of otitis media was as high as 91.7%. Common treatments for otitis media were conservative or surgical treatment. The medical treatment options include the use of decongestants, antihistamines, antibiotics and mucolytics. Surgical treatment options include grommet insertion, myringotomy. Unlike the case for children without clefts, cleft patient has a higher incidence of recurrence, so surgical treatment between the age of 3 month and 6 month was recommended. The effect of palatoplasty on middle ear disease has remained controversial. Early and periodic evaluation on the symptomatic infection or significant of hearing loss was recommended.

  • PDF