• Journal of Korean Medicine Rehabilitation
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• v.21 no.3
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• pp.33-43
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• 2011

Objectives : The purpose of this study was to investigate the influence of modified fasting therapy using fermented herbal medicine on the changes of body compositions. Methods : This study was carried out on 11 patients who carried out modified fasting therapy using fermented herbal medicine. They went through reducing food intakes period(7 days), fasting period(10~14 days) and refeeding period(10~14 days). Body compositions(weight, BMI(body mass index), skeletal muscle mass, body fat mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) were measured at each state. And then the data was analyzed. Results : 1. The weight and BMI decreased during the reducing food intakes period and the fasting period, and increased during the refeeding period. But the weight and BMI decreased during the fasting therapy period, as a whole. 2. The skeletal muscle mass decreased during the fasting period and increased during the refeeding period. As the final outcome, for the whole fasting therapy period, decrease of skeletal muscle mass didn't show significance. The body fat mass and percent body fat decreased during the reducing food intakes period, the fasting period and the refeeding period. 3. The basal metabolic rate decreased during the fasting period and increased during the refeeding period. As the final outcome, for the whole fasting therapy period, decrease of basal metabolic rate didn't show significance. 4. The waist-hip ratio decreased during the fasting period and the refeeding period. The visceral fat area decreased during the fasting period and refeeding period. Conclusions : Results from this investigation showed that modified fasting therapy using fermented herbal medicine have positive effects on changes of body compositions. This results are expected to compensate the defects of existing fasting therapy.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.4
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• pp.171-187
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• 2008

Objectives : The purpose of this study was to investigate the effects of modified fasting therapy on body composition, blood cell count and blood chemistry in inpatients. Methods : The modified fasting therapy program consists of three phases, a period of reducing food intakes, fasting and refeeding. Body weight, body composition, and the degree of obesity were estimated in before fasting therapy and after refeeding. Blood cell count and blood chemistry were estimated in before fasting therapy, before refeeding and after refeeding. Results : After modified fasting therapy, body weight, body fat mass, percent body fat, body mass index(BMI), body matabolic rate(BMR) and muscle mass was decreased significantly. WBC count and platelet count decreased significantly, RBC count and hemoglobin increased significantly and hematocrit was not changed significantly but within normal limit. AST and ALT increased significantly, especially patients group over BMI 25 within normal liver function. This study was not founded correlation between decreased muscle mass and increased liver function test. ALP, BUN, Total-cholesterol, and triglyceride decreased significantly. Creatinine increased significantly, but within normal limit. Sodium was not changed significantly, potassium decreased significantly but within normal limit. Conclusions : These results suggest that modified fasting therapy will be beneficial if several measures complement.

• Journal of Korean Medicine for Obesity Research
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• v.16 no.2
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• pp.116-123
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• 2016

Objectives: The purpose of this study was to investigate the effects of modified fasting therapy on the changes of body compositions. Methods: We analyzed the medical records of 33 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University from January 1st, 2011 to December 30th, 2015. They went through reducing food intakes period (7 days), fasting period (14 days) and refeeding period (14 days). Body compositions (weight, body mass index, skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) were reviewed at each state. And then the data was analyzed. Results: The body composition values (weight, body mass index [BMI], skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) decreased during the fasting therapy period, as a whole. The weight, BMI, percent body fat and visceral fat area decreased during the reducing food intakes period, the fasting period and the refeeding period. The skeletal muscle mass and basal metabolic rate significantly decreased during the reducing food intakes period and the fasting period, and insignificantly increased during the refeeding period. Conclusions: Results from this investigation showed that modified fasting therapy using fermented herbal medicine have positive effects on changes of body compositions.

• Journal of Korean Medicine for Obesity Research
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• v.17 no.2
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• pp.140-144
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• 2017

A highly obese female patient (body mass index=$30.8kg/m^2$) participated in a 10-day Gamrosu modified fasting therapy with soluble dietary fiber supplementation to enhance lipid metabolism. Gamrosu is a modified fasting therapy beverage which is made from medical herbs and carbohydrates (431 kcal/d). Before and after fasting, we evaluated the efficacy of therapy by measuring the changes of body composition and blood chemistry. After the modified fasting therapy, -6.1% of body weight and -5.6% of body fat mass were decreased. With regard to blood chemistry, all the plasma lipid levels were lowered. -37.4% of total cholesterol, -39.7% of low density lipoprotein cholesterol, -39.0% of triglyceride and -27% of high density lipoprotein (HDL) cholesterol were reduced. Further studies are needed to alleviate the reduction of HDL-cholesterol to apply the Gamrosu modified fasting to hyperlipidemia.

• Journal of Korean Medicine for Obesity Research
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• v.10 no.1
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• pp.49-56
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• 2010

This study was performed to report the effectiveness of modified fasting therapy using very-low-calorie-diet on a patient with obesity. The patient was diagnosed as severe obesity and participated in a 14-day fast with the Signature, a liquor which is made from fermented medical herbs and carbohydrates (intake <600 kcal/day) accompanying 7 prefasting relief days, and 16 days with stepwise reintroduction of food. The fasting patient also received intensive oriental medical treatments such as acupuncture, moxibustion, cupping therapy and was encouraged to take more than two hours' of walking exercise a day. We have evaluated the efficacy of treatments by measuring the changes of body composition and blood chemistry according to each period of fasting therapy. After treatment, Body Fat Mass of the patient was decreased more than Muscle Mass and the level of AST, ALT was decreased to normal range. These results suggest that the modified fasting therapy was effective on the patient with obesity.

• Journal of Korean Medicine for Obesity Research
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• v.16 no.1
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• pp.70-77
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• 2016

Gamrosu was originally conceptualized from Jeho-tang, a selected thirst quencher of the kings in Chosun Dynasty and Saeng-Maek-san, a qi-vigorating summer beverage recommended by Dongeuibogam. It is a modified fasting therapy beverage which is manufactured from the single herbal medicines composed of those two prescriptions. This study was conducted on 6 obese patients with hypertension. A modified fasting therapy with Gamrosu was practised on them for 10 consecutive days. After the therapy, their average blood pressures were descended from 148/89 mmHg to 119/79 mmHg. The modified fasting therapy with Gamrosu is supposed to be more effective than general diet program or dietary sodium reduction on controlling hypertension. And, Gamrosu improves anti-hypertensive effect by reducing the side effects, such as fatigue, electrolyte imbalance, heartburn, nausea, and headache, during the modified fasting therapy.

• Journal of Korean Medicine for Obesity Research
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• v.18 no.2
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• pp.152-158
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• 2018

The purpose of this study was to investigate the effects of modified fasting therapy using Gamrosu and herbal medicine on the changes of body compositions in women. We analyzed the medical records of 11 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University. Body compositions (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) were reviewed before and after modified fasting therapy. The body composition values (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) decreased after modified fasting therapy. Results from this investigation showed that modified fasting therapy using Gamrosu and herbal medicine has positive effects on changes of body compositions.

• Journal of Korean Medicine for Obesity Research
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• v.11 no.2
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• pp.69-74
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• 2011

Objectives: The modified fasting therapy(MFT) of traditional korean medicine uses very low calorie diet on a patient with chronic disease and obesity. During the fasting period of MFT, calorie intake is restricted under 600kcal. Adverse events such as hunger, heartburn, headache, and hair loss can occur because of fasting. In case of Gilbert's syndrome, Jaundice can arise without disorder of liver function and hemolysis because of increase of unconjugated bilirubin. We experienced a case of Gilbert's syndrome patient who appeared jaundice during the fasting period, so we report about that with literature review.

• Journal of Korean Medicine for Obesity Research
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• v.16 no.1
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• pp.36-49
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• 2016

Objectives: Two historical evidence supported the concept of Gamrosu. The first one was Jeho-tang, a selected thirst quencher in Chosun Dynasty and the second one was Saeng-Maek-san, Dongeuibogam's recommendation as one of the qi-vigorating summer beverages. Gamrosu is a modified fasting therapy beverage which is manufactured from those two prescriptions and the carbohydrates (420.6 kcal/d). A retrospective observational study was conducted to evaluate the clinical outcomes. Methods: Thirty-three cases were reviewed at three local Korean Medical clinics that each site's participant has finished the modified fasting for 10 consecutive days. Clinical outcomes were reviewed at pre- and post-fasting sessions by retrieving the changes of body composition, blood pressure, blood chemistries & urine tests, and subjective symptoms & fatigue scores. Results: Demographics of the observed participants were 17 of male and 16 of female. Post-Gamrosu session, -6.89% of body weight, -8.97% of body fat mass were reduced with the nutrition indices being improved (P<0.001). -8.72% of systolic blood pressure, -39.86% of serum triglyceride, -6.75% of fast blood sugar and -8.12% of waist circumference were improved (P<0.05). The levels of high sensitivity C-reactive protein (-58.34%), CRP (-43.55%) and eosinophil (-21.30%) showed the significant diminished profiles (P<0.05). Liver/kidney functions and the standard of electrolytes were maintained within normal range in stable manners. The fatigue scale scores indicated significant lower scores. Conclusions: Taken together, obesity-related clinical outcomes after a modified fasting therapy with Gamrosu were sufficiently feasible and the observed findings should be considered for further prospective clinical studies.

• Journal of Korean Medicine for Obesity Research
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• v.15 no.2
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• pp.153-161
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• 2015

Gamrosu is a modified fasting therapy beverage (431 kcal/d). A retrospective observational study was conducted to investigate the detoxification feasibility of Gamrosu. Three cases were reviewed which participants have finished the fasting with Garmrosu for 10 consecutive days. Detoxification profiles of Gamrosu were reviewed at pre- and post-fasting sessions. Post-Gamrosu session, -6.3% of average weight, -6.5% of average body fat mass and -6.6% of average muscle mass were reduced with the nutrition indices being improved. The inflammation indices showed the significant diminished profiles. Liver/kidney functions and the standard of electrolytes were maintained within normal range in stable manners, however, marginal elevation of total bilirubin and mild ketoacidosis were observed. The indices of oxidative stress decreased and those of antioxidative activity increased. The fatigue scale scores indicated lower scores except insomnia symptom. Taken together, detoxification profiles of Gamrosu were sufficiently feasible and the observed findings should be considered for further clinical studies.