• 제목/요약/키워드: Morphological Change

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Inhibition of Stem Cell Factor- and Nerve Growth Factor-Induced Morphological Change by Wortmannin in Mast Cells

  • Kim, Hyung-Min;Moon, Young-Hoe;An, Nyun-Hyung
    • Archives of Pharmacal Research
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    • 제22권2호
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    • pp.108-112
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    • 1999
  • Recombinant murine stem cell factor (rmSCF) or recombinant murine nerve growth factor (rmNGF) induced the morphological change of large numbers of rat peritoneal mast cells (RPMC). We investigated the role of phosphatidylinositol $3^{l}-kinase$ (PI3-kinase) in receptors-mediated morphological change in RPMC. Exposure of RPMC to PI3-kinase inhibitor, wortmannin, before the addition of rmSCF and rmNGF antagonized those factors-induced morphological change. These results suggest that the PI3-kinase is involved in the signal transduction pathway responsible for morphological change following stimulation of rmSCF and rmNGF and that wortmannin blocks these responses.

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직선 개수로 횡단면에서의 소류사 이송과 지형 변화 (Bedload Sediment Transport and Morphological Change in Cross Sections of Straight Open-Channel)

  • 치엔반팜;김태범;최성욱
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2010년도 학술발표회
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    • pp.62-66
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    • 2010
  • This study presents velocities of bedload sediment transport in both longitudinal and lateral directions and applied in considering morphological change of straight open channel. The velocities of particle motion have obtained by considering the forces balance acting on particles on the bed between the drag, tangential component of the immersed weight of the particle, and Coulomb's resistive forces. Numerical profiles of particle motion velocities reveals good agreement in comparison between this study and Kovacs and Parker (1994). The evaluated velocities components of particle transport are get used to estimate bedload transport rate in considering morphological change of straight open channel. For the application, numerical solution is applied to laboratory experiment which shows very close solution profiles between this study and observed data of a self-formed straight channel.

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부산 아파트 단지 배치형태 변화의 요인과 과정에 관한 연구 (Determinants and Processes of Morphological Transformation of Apartment Complexes in Busan)

  • 이상진;박소현
    • 대한건축학회논문집:계획계
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    • 제35권3호
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    • pp.91-102
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    • 2019
  • This study explores the causes and processes of morphological transformation of apartment complexes in Busan. All apartment complexes built until the year 2016 were selected for statistical analysis, drawing/map examination, field observation, selected expert interviews based on 6 periodical groups: Period I(~1990), Period II(1991~1995), Period III(1996~2000), Period IV(2001~2005), Period V(2006~2010), and Period VI(2011~2016). The research argues for three 'arrangement' types, P1U, L1U and P2U, which have dominated the whole periods occupying 88% of the total 260 complexes. The switch of the leading type represents for morphological transformation of apartment complexes. Four aspects, density(F.A.R.), height(maximum number of floors), deformed-building-type ratio, and building-orientation, have affected the change of 'arrangement' types. Density was the major cause of the arrangement-type switch, from P1U to L1U, on Period II(1991~1995). The morphological change, from type L1U to P2U, on Period V(2006~2010) was caused by height and orientation, and is correlated with the increased number of deformed-type buildings. The first phase morphological change on Period II(1991~1995) was resulted by the supply side of apartment. However, the second phase transformation on Period V(2006~2010) had gone through the complex process including reflection of consumers' demands. The significance of research is to reveal the morphological transformation process of apartment complexes through analytical investigation of the entire apartment data in Busan. The result shows that the major change of urban paysage started to occur from Period V(2006~2010), and the superficial evaluation on apartment 'being monotonous and repetitive' may not be proper at least from the perspective of town plan.

부산 아파트 단지의 주동 평면형태의 변화 특성에 관한 연구 (Morphological Transformation of Building Blocks of Apartment Complexes in Busan)

  • 이상진;박소현
    • 대한건축학회논문집:계획계
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    • 제35권8호
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    • pp.3-14
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    • 2019
  • The research is to track the morphological transformation of residential towers of apartment complexes in Busan. Though apartment is one of the most important components in Korean society, it has not drawn enough attention from academia as well as the public, especially regarding its shape. In result, its morphological change has barely been recognized. Instead, negative, but superficial, evaluation has become dominant tendency to deal with the shape of apartment tower. There are numerous 'partial' evidences to inform the morphological change of apartment plan type, and understanding the change is critical since morphological resultant reflects culture, politics, economy of a society. The research has been done on the 261 apartment complexes built through 2016 in Busan. The analysis shows that $I^0$ type, to represent 'typical boring architectural shape' of Korean apartments, has been dominant until the year 2000. However, its portion has become drastically decreased since the mid-2000. Composite plan type, the geometrical precedents of which had never been existent, emerged in the mid-2000, and this phenomenon may symbolize the change of morphology of apartment. When tower plan types are grouped together according to geometrical shape, three types, I-type, L-type and Y-type, take the most of residential towers, explaining 97% of the total. As expected, I-type is the most dominant, but its influence has decreased as time passes. Y-type might become one of the most important type in the period V. L-type has become the leading type in the Period VI to exceed I-type by 12 percent.

Modeling of Fine Sediment Transport under Multiple Breakwaters of Surface-Piercing Type

  • Lee, J. L.;Oh, M. R.
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2004년도 학술발표회
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    • pp.557-562
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    • 2004
  • A surface-piercing barrier model is presented for understanding morphological development in the sheltered region and investigating the main factors causing the severe accumulation. Surface-piercing structures like vertical barriers, surface docks and floating breakwaters are recently favored from the point of view of a marine scenario since they do not in general partition the natural sea. The numerical solutions are compared with experimental data on wave profiles and morphological change rates within a rectangular harbor of a constant depth protected by surface-piercing thin breakwaters as a simplified problem. Our numerical study involves several modules: 1) wave dynamics analyzed by a plane-wave approximation, 2) suspended sediment transport combined with sediment erosion-deposition model, and 3) concurrent morphological changes. Scattering waves are solved by using a plane wave method without inclusion of evanescent modes. Evanescent modes are only considered in predicting the reflection ratio against the vertical barrier and energy losses due to vortex shedding from the lower edge of plate are taken into account. A new relationship to relate the near-bed concentration to the depth-mean concentration is presented by analyzing the vertical structure of concentration. The numerical solutions were also compared with experimental data on morphological changes within a rectangular harbor of constant water depth. Through the numerical experiments, the vortex-induced flow appears to be not ignorable in predicting the morphological changes although the immersion depth of a plate is not deep.

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부산신항 건설이 진우도 주변 해저지형 변화에 미치는 영향 - 수치실험을 통한 정성적 평가 (Morphological Change in Seabed Surrounding Jinwoo-Island Due to Construction of New Busan Port - Qualitative Evaluation through Numerical Simulation)

  • 홍남식
    • 한국해양공학회지
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    • 제32권3호
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    • pp.192-201
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    • 2018
  • In this study, a qualitative evaluation of the morphological changes in the seabed surrounding Jinwoo-Island due to the construction of the new Busan port were determined through a numerical simulation. Various scenarios for the discharge of the Nakdong river estuary dam and construction stage of the new Busan port were established and utilized for an indirect and qualitative investigation through simulation using the numerical model implemented in this study. It was concluded through a qualitative study that the morphological changes in the seabed surrounding Jinwoo-Island were typical estuary seabed changes due to the discharge of the Nakdong river estuary dam and waves from the open sea. The effects from the construction of the new Busan port were relatively small.

해안사구에서의 유효풍속과 지형변화 (The Effective Wind Velocity and the Patterns of Morphological Change in the Coastal Dune Area)

  • 서종철
    • 한국지역지리학회지
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    • 제10권3호
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    • pp.667-681
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    • 2004
  • 이 연구의 목적은 태안반도 신두해안사구의 유효풍속과 지형변화의 관계를 밝히는 것이다. 퇴적물의 유동은 8개의 횡단면에서 침식핀을 이용하여 1999년 7월부터 2000년 7월까지 고도변화를 측정한 후 계산되었다. 연구결과가 시사하는 바는 다음과 같다. 첫째, 사구지역에서의 지형변화와 유효풍속에 근거하여 퇴적기와 침식기가 구분되었다. 퇴적기는 11월부터 4월까지로 모래의 집적이 주로 전사구에서 일어났으며 순차적으로 사구평지로 이어졌다. 침식기는 5월부터 10일까지로 전사구의 말단부에서 소규모 침식과 퇴적이 반복되는 패턴을 보였다. 둘째. 조사기간 동안 조사지역에서의 전체 퇴적물수지는 $10.2\;m^3$/m/yr로 잉여로 나타났으나 지역적인 차이가 나타났다. 이차사구에서는 결핍되는 곳도 나타났다. 사구지역의 북단에서는 모래의 공급이 활발하게 이루어지고 있는 반면 중앙부와 남부지역에서는 모래의 공급이 빈약했다.

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맥반석 식이가 십자매와 백문조 간장 및 신장의 형태학적 변화에 미치는 영향 (Effect of Quartz Porphyry on the Functional and Morphological Changes of Liver and Kideny in Common Finch and white Java Sparrow)

  • 차재영;조영수;홍숙희;임정부;김대진
    • 생명과학회지
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    • 제11권2호
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    • pp.126-132
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    • 2001
  • Effect of Quartz porphyty(QP) on functional and morphological changes of the liver and kidney was studied in male common finch and white java sparrow fed with the basal diet(Control group) or experimental diet containing 3.0% QP(QP group) for 14 days. There was not significantly different morphological change of the liver upon light microscopic examination in common finch and white java sparrow between control group and QP group. Morphological change of renal tissue upon light microscopic examination in common finch and white java sparrow was not also significantly different between control group and QP group. The concentrations of serum creatinine, blood urea nitrogen, and nric acid as renal functional parameters of common finch and white java sparrow were not significantly different in the both groups. The activity of glutamic oxaloacetic transaminase(GOT) as hepatic functional parameter in common finch was significantly higher in the QP group($\rho$<0.05), whereas the activity of glutamic pyruvic transaminase(GPT) as hepatic functional parameter in common finch was not significantly different in the both groups. The activities of GOP and GPT in white java sparrow were not significantly different in the both groups. The morphologic findings and functional parameters of the liver and kidney observed in common finch and white java sparrow fed with 3.0% QP diet showed evidence of slightly liver damage accompanied with increased release of enzyme and fatty change of the hepatocytes in common finch, suggested that the tissues in some animals can be damaged by feeding a diet supplemented with 3.0% QP.

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군산의 근대도시발달과정과 도시조직의 변화 유형에 관한 형태학적 연구 (A Morphological Study on the Modern Urbanization and Transformation Type of Urban Tissues in Kunsan)

  • 이경찬;허준
    • 한국조경학회지
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    • 제32권6호
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    • pp.36-51
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    • 2005
  • The purpose of this thesis is to analyse modem urbanization process and the morphological transformation of the urban tissues in Kunsan between the you 1899 and 2001, The method of this study is to investigate the transformation process of morphological elements such as plot structure, building layout, building facades, land use, exterior space structure and their use, with actual field surveys, the analysis of land registration maps in 1912, and various topological map. Morphological analysis on modern Kunsan is progressed by three steps-typo-morphological analysis of urban tissue in old-town area, interpretation of morphological process, and transformation process, of morphological structure in Japanese concession in view of plots system. As a result, it is found that there is cyclical relationship among the morphological transformation processes of morphological elements, plots, buildings, land-uses, and access space to buildings. From the view of town plan change, the period of restoration of war damage in 1950s and compressive growing period in 1960s have important meaning in the morphological process of old-town area. Particularly the first building plan and layout type together with plot form and structure is acted as the main factor to decide the subsequent plot transformation system, exterior space system and the particular streetscape in Kunsan.

Disinfection by Ozone Microbubbles Can Cause Morphological Change of Fusarium oxysporum f. sp. melonis Spores

  • Tamaki, Masahiko;Kobayashi, Fumiyuki;Ikeura, Hiromi;Sato, Michio
    • The Plant Pathology Journal
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    • 제34권4호
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    • pp.335-340
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    • 2018
  • To investigate the difference in the disinfectant efficiency of ozone microbubbles ($O_3MB$) and ozone millibubbles ($O_3MMB$), the morphological change of the treated Fusarium oxysporum f. sp. melonis spores was observed with scanning and transmission electron microscopies (SEM and TEM). The disinfectant efficiency of $O_3MB$ on F. oxysporum f. sp. melonis spores was greater than that of $O_3MMB$. On observation with SEM, it was revealed that morphological change of F. oxysporum f. sp. melonis spores was caused by $O_3MB$ and $O_3MMB$, and damage to the spore surfaces by $O_3MB$ occurred sooner than that by $O_3MMB$. On observation with TEM, it was furthermore confirmed that F. oxysporum f. sp. melonis spores treated with $O_3MB$ induced wavy deformation of cell membrane and the intracellular change different from that with $O_3MMB$. Therefore, the greater disinfection efficiency of $O_3MB$ was suggested to be caused due to the function of the MB in addition to the oxidative power of $O_3$.