• Title/Summary/Keyword: NO%24_2%24

Search Result 8,842, Processing Time 0.042 seconds

A Study on Bilge Pumping Performance of 24,000TEU class Container Ship (24,000TEU급 컨테이너선박의 빌지 펌핑 성능에 대한 고찰)

  • Seo, Jang-Won;Yun, Jeong-In;Lee, Kyoung-Woo;Lee, Won-Ju;Park, Hoyong;Choe, Su-Jeong;Choi, Jae-Hyuk
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.28 no.6
    • /
    • pp.1100-1109
    • /
    • 2022
  • Herein, a case study was conducted on the bilge pumping performance of a 24,000TEU class container ship with an overall length of 400m. Although the bilge system of the 24,000TEU class container ship was designed in accordance with the rule requirements of the Classification Society, the bilge system did not satisfy the 2 m/s requirements of SOLAS Reg.II-1/35-1 under the rated flow rate and maximum flow rate conditions of the bilge pump installed in the ship. In particular, assumptions were made that No.1 ~ No.4 cargo holds were flooded and filled entirely by sea water and the evaluation of bilge pumping performance had been performed for No.1 ~ No.4 cargo holds. According to the evaulation results of the, the mean water velocity at the main bilge pipe for No.2, No.3, and No.4 cargo holds did not meet the 2 m/s criterion. To resolve this problem, in this study, the branch bilge pipe in each cargo hold was changed from 150A to 200A and the mean water velocity at the main bilge pipe for No.2, No.3, and No.4 was calculated as 2.479m/s, 2.476m/s, and 2.459m/s, respectively.

Gonadotropins and Nitric Oxide Can Suppress the Expression of Mouse Follicular Bad and Bax Genes (생식소 자극 호르몬과 NO에 의한 생쥐 여포의 Bad와 Bax 유전자 조절)

  • 김외리
    • Development and Reproduction
    • /
    • v.1 no.2
    • /
    • pp.165-172
    • /
    • 1997
  • the pupose of this study was to investigate the effects of gonadotropin and nitric oxide (NO) on the expression of mouse follicular bad and bax genes that are known induce apoptosis. Large and midium size follicles of immature mice were obtained at 0, 24, and 48 hours time intervals after Pregnant Mare's Serum gonadotropins(PMSG, 5 I.U.) injection. Preovulatory follicles collected at 24 hrs after PMSG injection were cultured with or without various chemicals such as gonadotropin, gonadotropin Releasing hormone(GnRH), testosterone, Sodium nitroprusside (SNP) for 24 hrs at $37^{\circ}C$. After 24 hrs culture, the culture media was used for nitrite assay and total RNA was extracted, subjected to RT-PCT for the analyses of bad and bax expression. We found that expression of bad and bax genes in follicles was markedly reduced before and after in vivo priming with hCG. When the preovulatory follicles were cultured for 24 hrs in culture media with PMSG and hCG, the expression of bad and bax genes was decreased. Moreover, SNP (NO generating agent) can significantly suppress the expression of bad and bax genes in follicles when apoptosis was induced by GnRH agonist and testosterone. At the same time, nitrite production of culture media was increased in GnRH agonist + SNP, testosterone + SNP and SNP treated groups than control group. These data demonstrated for the first time that peptide hormones and NO may play important roles in the regulation of mouse follicular differentiation and may prevent apoptosis via supressing the expression of bad and bax genes.

  • PDF

Pre- and post-initiation modulating effects of green tea ingestion on rat hepatocarcinogenesis

  • Kim, Hyung-Sook;Kim, Hee-Seon;Choi, Hay-Mie
    • Nutrition Research and Practice
    • /
    • v.2 no.4
    • /
    • pp.234-239
    • /
    • 2008
  • The purpose of this study was to investigate the effects of green tea ingestion on hepatocarcinogenesis before and after its initiation. Male Sprague-Dawley rats were fed an AIN76A diet with or without green tea. Initiation was induced by a single dose (200 mg/kg) of diethylnitrosamine at week 4 and 0.02% (w/w) 2-acetylaminofluorene was supplied in the diets. The control group had free access to water for 13 weeks (CTR13). Tea infusion was provided from the beginning of the experiment for 13 weeks (PRE13) or from the post-initiation stage until week 13 (POST13). Three other groups (CTR24, PRE24 and POST24) were added to examine the longer-term effects (24 weeks) with the same experimental design. The percentage area of liver sections that were positive for hepatic placental glutathione S-transferase (GST-P), which was used as a marker of preneoplastic lesions, was smaller in PRE13 ($20.2{\pm}5.0%$, $mean{\pm}SD$) and POST13 ($26.0{\pm}4.8%$) than in CTR13 ($33.2{\pm}5.8%$, p<0.05). Over the longer period, the GST-P lesions were significantly smaller for both PRE24 and POST24 ($21.6{\pm}8.5%$ and $22.2{\pm}4.0%$, respectively) than for CTR24 ($28.6{\pm}5.1%$, p<0.05), but there was no significant difference between PRE24 and POST24. The liver content of thiobarbituric acid reactive substances was significantly lower in the tea groups than in the controls (p<0.05). However, no significant differences were observed among groups of GST activity. The results show that tea consumption exhibits a stronger short-term initiation-inhibiting ability in liver carcinogenesis, but over a longer period, the preventive effects of green tea ingestion do not differ in post- and pre-initiation.

Validity of Estimating Sodium Intake using a Mobile Phone Application of 24-hour Dietary Recall with Meal Photos (식사사진을 이용한 24시간 식사 회상 모바일 폰 앱의 나트륨 섭취 추정 타당성 연구)

  • Kim, Seo-Yoon;Chung, Sang-Jin
    • Korean Journal of Community Nutrition
    • /
    • v.25 no.4
    • /
    • pp.317-328
    • /
    • 2020
  • Objectives: The objective of this study was to verify the validity of a mobile phone application (app) that applies a 24-hour dietary recall with meal photos, as a means of being a more accurate method of estimating dietary sodium intake. Methods: Of the 203 subjects enrolled, 172 subjects (84 males and 88 females) were selected for the final analysis, excluding those with an intake less than 500 kcal and urine output less than 500 ml. Dietary sodium assessment methods used for comparing with the 24-hour urinary sodium excretion are as follows: 1) face-to-face 24-hour dietary recall, 2) 24-hour dietary recall using the mobile app, 3) face-to-face 24-hour dietary recall considering liquid intakes from soup, stew, water kimchi and noodle, etc (liquid-based dishes), 4) 24-hour dietary recall using the mobile app considering liquid intakes from liquid-based dishes, and 5) food frequency questionnaire. Repeated ANOVA with Bonferroni method was used for comparing the average sodium intake, and Pearson's correlation was applied to correlate the methods used. Results: In women, no significant difference was observed in the average sodium intake between all methods. Moreover, analysis in men and total adults revealed no significant difference between the 24-hour urinary sodium secretion, and 24-hour dietary recall using the app and 24-hour dietary recall using the app considering liquid intakes. Sodium intake by food frequency questionnaire was significantly different when compared with the intake determined from 24-hour urinary sodium excretion. Sodium intake from all methods (except food frequency questionnaire) significantly correlated with values obtained from 24-hour urine sodium excretion. Conclusions: Results of this study validated a mobile phone app using a 24-hour dietary recall with meal photos to better estimate dietary sodium intakes. It is believed that further studies in the future will enable the application as a tool to more accurately determine sodium intake.

ON THE EXTREMAL TYPE I BINARY SELF-DUAL CODES WITH NEAR-MINIMAL SHADOW

  • HAN, SUNGHYU
    • Journal of applied mathematics & informatics
    • /
    • v.37 no.1_2
    • /
    • pp.85-95
    • /
    • 2019
  • In this paper, we define near-minimal shadow and study the existence problem of extremal Type I binary self-dual codes with near-minimal shadow. We prove that there is no such codes of length n = 24m + 2($m{\geq}0$), n = 24m + 4($m{\geq}9$), n = 24m + 6($m{\geq}21$), and n = 24m + 10($m{\geq}87$).

Antidiabetic Activity and Enzymatic Activity of Commercial Doenjang Certified for Traditional Foods (전통식품 품질인증 일부 시판 된장의 효소활성 및 항당뇨 활성)

  • Lee, So-Young;Kim, In-Sun;Park, So-Lim;Lim, Seong-Il;Choi, Hye-Sun;Choi, Shin-Yang
    • KSBB Journal
    • /
    • v.27 no.6
    • /
    • pp.361-366
    • /
    • 2012
  • We investigated the anti-diabetic activity and enzymatic activity of 24 commercial doenjang samples certified for traditional foods. Twenty four doenjang samples showed the wide ranges in enzymatic activities (protease activities 0-50.45 unit/g, ${\alpha}$-amylase activities 0-675.9 unit/g, ${\beta}$-amylase 13.6-308.6 unit/g), and there were no difference in enzymatic activity by the producing region. To evaluate the potential anti-diabetic activity of 24 doenjang samples, we examined the effect of doenjang methanol extract (DME) on 2-[n-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl) amyno]-2-deoxy-d-glucose (2-NBDG) uptake. Ten samples among 24 samples significantly stimulated the uptake of 2-NBDG. When the cells were treated with DME at 400 ug/mL, No. 17 and 23 specially stimulated 2-NBDG uptake by 1.23-fold and 1.25-fold, respectively, compared with untreated control cell. And there were no cytotoxicity in the C2C12 cells treated with DME at concentration of 500 ug/mL. Among 24 samples, No. 6, 7, 12, 21 and 24 showed the ${\alpha}$-glucosidase inhibitor activity at concentration of 10 mg/mL; however, they were less effective than acarbose which is a commercial ${\alpha}$-glucosidase inhibitor.

Immune Enhancing Effect of Houttuyniae Herba on Mouse Macrophage (어성초(魚腥草)의 면역활성에 미치는 영향)

  • Kim, Jeong-Hyun;Kim, Yoon-Sang;Lim, Eun-Mee
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.25 no.2
    • /
    • pp.12-22
    • /
    • 2012
  • Objectives: The aim of this study is to investigate immune enhancing effect of Houttuyniae Herba water extract(HW) on RAW 264.7 cell of mouse macrophages. Methods: Effects of HW on productions of nitric oxide(NO) and hydrogen peroxide($H_2O_2$) in RAW 264.7 mouse macrophages were measured. Effect of HW on production of cytokines such as interleukin(IL)-$1{\beta}$, IL-6, and tumor necrosis factor(TNF)-${\alpha}$ in RAW 264.7 cells was accessed by a multiplex bead array assay based on xMAP technology. All of results were represented P<0.05 compared to the normal. Results: 1. After 24 hr incubation, HW increased significantly NO production in RAW 264.7 cells at the concentrations of 25, 50, 100 and 200 ${\mu}g$/mL. 2. After 24 hr incubation, HW increased significantly hydrogen peroxide production in RAW 264.7 cells at the concentrations of 25, 50, 100 and 200 ${\mu}g$/mL. 3. After 24 hr incubation, HW increased significantly IL-$1{\beta}$ production in RAW 264.7 cells at the concentrations of 100 and 200 ${\mu}g$/mL. 4. After 24 hr incubation, HW increased significantly IL-6 production in RAW 264.7 cells at the concentrations of 100 and 200 ${\mu}g$/mL. 5. After 24 hr incubation, HW increased significantly TNF-${\alpha}$ production in RAW 264.7 cells at the concentrations of 50, 100, and 200 ${\mu}g$/mL. Conclusions: These results suggest that HW has immune enhancing activity related with its increasement of NO, hydrogen peroxide, IL-$1{\beta}$, IL-6, and TNF-${\alpha}$ in macrophages.