• Title/Summary/Keyword: NSS

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Measurement Study at Kosan, Cheju Island during March-April, 1994: (I) Transport of Ambient Aerosol (고산에서의 1994년 3월 - 4월 측정연구: (I) 입자상 오염물질의 이동)

  • 김용표;박세옥;김진영;심상규;문길주;이호근;장광미;박경윤;강창희
    • Journal of Korean Society for Atmospheric Environment
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    • v.12 no.1
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    • pp.79-90
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    • 1996
  • Total suspended particles were measured at Kosan, Cheju Island, Korea during the period of March 11 .sim. April 19, 1994. Concentrations of non-sea salt(nss) ions were higher than those measured at clean marine areas in Japan and other background marine areas in the world. Especially, nss sulfate concentration is compatable to thoes measured at Seoul. It is suggested that most nss sulfate concentration is originated from anthropogenic sources. Nss sulfate concentration shows strong correlation with ammonium and nss potassium concentrations while shows no a pparent correlation with nitrate and nss calcium concentrations. Nss calcium concentrations shows strong correlation with nss potassium and mss magnesium concentrations. It is deduced that nss potassium has two origins, one anthropogenic, the other crustal. Backward trajectory analysis results show the trajectories of air parcel during the measurement period were mostly originated from China. It is shown that cases of high nss sulfate with high nss calcium can occur when an air parcel originated from arid and semi-arid regions of morthwestern China or Mongolia passes through northeastern China.

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Experimental Study of Naesosan(內消散) on the Effects of Anti-Cancer (內消散의 抗癌效果에 관한 實驗的 硏究)

  • Park, Su-Yeon;Choe, Jeong-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.14 no.1
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    • pp.154-166
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    • 2001
  • Naesosan(NSS) has been used in Oriental Medicine as a drug that treated carbuncle and cellulitis. So, the purpose of this Study was to investigate effects of NSS on the cytotoxicity of cancer cell lines and lymphocytes in vitro, proliferation of Ll210 cells and lymphocytes in L1210 cells transplanted mice, improvement of blood count in Ll210 cells transplanted mice, tumor weight and body weight in sarcoma-180 cells transplanted mice, survival prolongation in sarcoma-180 cells transplanted mice. We used NSS extract with freeze-dried, 8wks-old male mice(balb/c and ICR mouse $18{\pm}2g$). Ll210 cell lines, and sarcoma-180 cell lines for this Study, The proliferation of cells was tested using a colorimetric tetrazoliun assay(MTT assay). The results of this Study were obtained as follows ; 1. NSS showed significantly cytotoxicitic effects of cancer cell lines, did not show cytotoxicitic effects of lymphocytes. 2, Proliferation of lymphocytes in L1210 cells transplanted mice did not effects by NSS. 3. NSS inhibited significantly the proliferation of L1210 cells in L1210 cells transplanted mice. 4. NSS improved significantly the blood count in Ll210 cells transplanted mice. 5. NSS increased significantly th body weight in sarcoma-180 cells transplanted mice. 6. NSS dereased significantly the tumor weight in sarcoma-180 cells transplanted mice. 7. NSS prolonged significantly the survival time in sarcoma-180 cells transplanted mice.

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A Study on Ion Distribution and Behavior of Acidrain in Mokpo and Yeochon Area (목포, 여천지역 강수의 무기이온 성분농도와 거동에 관한 연구)

  • 오길영;양수인;이완진
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.4
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    • pp.385-392
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    • 1999
  • This study was carried out to investigate the constituents of inorganic ions of precipitation in Mokpo and Yeochon area from Jan. 1996 to Dec. 1997. The volume-weighted mean pH of precipitation was 5.7(4.8~7.8) at Mokpo, and 5.6(5.1~7.4) at Yeochon area, respectively. The non-seasalt(nss) anion concentrations were found in order of $nss-SO^{2-}_4>NO^-_3>nss-Cl^-$ at two areas. The portion of $nss-SO^{2-}_4;and;NO^-_3$ was 71~84% out of anions. The the non-seasalt cation concentrations were found in order of $NH^+_4>nss-Ca^{2-}>nss-Mg^{2+}>nss-K^-$ at two areas. The portion of $NH^+_4;and; nss-Ca^{2+}$ was 85~92% out cations. Compared regionally the year concentraton of $nss-SO^{2-}_4$, the result of Yeochon was 3 times higher than that of Mokpo in 1996, while the results of two regions were almost similar in 1997. The reason was that Yeochon was restricted area of the use of 0.5% sulfur B-C oil, controlled air pollution emission area, controlled semitotal amounts of air pollution emission area and partial operating of factories in 1997. There were no ions having high correlation with $H^+,;but;nss-SO^{2-}_4,;NO^-_3,;NH^+_4;and;nss-Ca^{2+}$ showed high correlation coefficient each other. It seems that these ions have little correlation with $H^+$ because they are washed out on binding state. Factor analysis showed that the first factor was complicated factor containing anthropogenic and soil resource, the second factor was sea-salt resource and the third factor was independent behavior of hydrogen at Mokpo. While, the first factor was complicated factor containing anthropogenic and sea-salt resource, the second factor was $Ca(NO_3)_2$ salt and the third factor was $NH^+_4;and;SO^{2-}_4$ synergied by resource and combination at Yeochon.

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Design of the Network Streaming Service based on Linux (Linux 상에서의 Network Streaming Service 설계)

  • 김영만;박홍재;허성진;최완
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10c
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    • pp.370-372
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    • 2004
  • 본 논문에서는 개방형 운영체제인 리눅스상에서 package streaming service를 제공하는 Network Streaming Service(통칭 NSS)를 설계하는 문제를 다룬다. NSS는 client가 serve 측에 설치된 소프트웨어 package를 마치 client 자신의 local disk상에 이미 인스톨된 패키지를 실행하는 것처럼 동작하도록 해준다. NSS는 client측의 NSS Mounter, Package Streaming Consumer, NSS Configurator와 server측의 NSS Load Balancer, Package Streaming Supplier, NSS Manager, Accounting & Security Manager로 구성되며 local disk caching과 background prefetching 기능을 사용하여 향상된 서비스를 제공한다.

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Design of the Prefetching Algorithm in the NSS (NSS(Network Streaming Service) 상에서의 Prefetching Algorithm 설계)

  • 김영만;한왕원;허성진;최완
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10c
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    • pp.373-375
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    • 2004
  • 본 논문에서는 클라이언트가 NSS서버에서 제공하는 패키지를 네트워크 스트리밍을 통하여 실시간으로 이용 가능하게 해주는 리눅스[1]기반의 NSS(Network Streaming Service) 시스템 상에서 패키지 prefetching 기능을 제공하는 부분에 대한 효율적인 알고리즘의 설계를 다룬다.

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Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Phlebovirus Inhibits TBK1 to Evade Interferon-Mediated Response

  • Lee, Jae Kyung;Shin, Ok Sarah
    • Journal of Microbiology and Biotechnology
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    • v.31 no.2
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    • pp.226-232
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    • 2021
  • Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging phlebovirus of the Phenuiviridae family that has been circulating in the following Asian countries: Vietnam, Myanmar, Taiwan, China, Japan, and South Korea. Despite the increasing infection rates and relatively high mortality rate, there is limited information available regarding SFTSV pathogenesis. In addition, there are currently no vaccines or effective antiviral treatments available. Previous reports have shown that SFTSV suppresses the host immune response and its nonstructural proteins (NSs) function as an antagonist of type I interferon (IFN), whose induction is an essential part of the host defense system against viral infections. Given that SFTSV NSs suppress the innate immune response by inhibiting type I IFN, we investigated the mechanism utilized by SFTSV NSs to evade IFNmediated response. Our co-immunoprecipitation data suggest the interactions between NSs and retinoic acid inducible gene-I (RIG-I) or TANK binding kinase 1 (TBK1). Furthermore, confocal analysis indicates the ability of NSs to sequester RIG-I and related downstream molecules in the cytoplasmic structures called inclusion bodies (IBs). NSs are also capable of inhibiting TBK1-interferon regulatory factor 3 (IRF3) interaction, and therefore prevent the phosphorylation and nuclear translocation of IRF3 for the induction of type I IFN. The ability of SFTSV NSs to interact with and sequester TBK1 and IRF3 in IBs demonstrate an effective yet unique method utilized by SFTSV to evade and suppress host immunity.

Snow Influence on the Chemical Characteristics of Winter Precipitation (강설이 겨울철 강수의 화학적 특성에 미치는 영향)

  • Kang, Gong-Unn;Kim, Nam-Song;Oh, Gyung-Jae;Shin, Dae-Yewn;Yu, Du-Cheol;Kim, Sang-Baek
    • Journal of Korean Society of Environmental Engineers
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    • v.29 no.1
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    • pp.113-125
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    • 2007
  • To know the differences in ionic compositions in rain and snow as well as snow influence on the chemical characteristics of winter precipitation, precipitation samples were collected by the wet-only automatic precipitation sample, in winter(November-February) in the Iksan located in the northwest of Chonbuk from 1995 to 2000. The samples were analyzed for concentrations of water-soluble ion species, in addition to pH and electrical conductivity. The mean pH of winter precipitation was 4.72. According to the type of winter precipitation, the mean pH of rain was 4.67 and lower than 5.05 in snow. The frequencies of pH below 5.0 in rain were about 73%, while those in snow were about 30%. Snow contained 3 times higher concentrations of sea salt ion components originated from seawater than did rain in winter, mainly $Cl^-,\;Na^+$, and $Mg^{2+}$. Neglecting sea salt ion components, $nss-SO_4^{2-}$ and $NO_3^-$ were important anions and $NH_4^+$ and $nss-Ca^{2+}$ were important cations in both of rain and snow. Concentrations of $nss-SO_4^{2-}$ was 1.3 times higher in rain than in snow, while those of $nss-Ca^{2+}$ and $NO_3^-$ were 1.5 and 1.3 times higher in snow, respectively. The mean equivalent concentration ratio of $nss-SO_4^{2-}/NO_3^-$ in winter precipitation were 2.4, which implied that the relative contribution of sulfuric and nitric acids to the precipitation acidity was 71% and 29%, respectively. The ratio in rain was 2.7 and higher than 1.5 in snow. These results suggest that the difference of $NO_3^-$ in rain and snow could be due to the more effective scavenging of $HNO_3$ vapor than particulate sulfate or nitrate by snow. The lower ratio in snow than rain is consistent with the measurement results of foreign other investigators and with scavenging theory of atmospheric aerosols. Although substantial $nss-SO_4^{2-}$ and $NO_3^-$ were observed in both of rain and snow, the corresponding presence of $NH_4^+,\;nss-Ca^{2+},\;nss-K^+$ suggested the significant neutralization of rain and snow. Differences in chemical composition of non-sea salt ions and neutralizing rapacity of $NH_4^+,\;nss-Ca^{2+}$, and $nss-K^+$ between rain and snow could explain the acidity difference of rain and snow. Snow affected that winter precipitation could be less acidic due to its higher neutralizing rapacity.

Analysis on Characteristics of Pigments Manufactured with Various Neorok Produced from Mt. Gwangjeongsan, Pohang (포항 광정산 일대 산출 뇌록으로 제조한 안료의 특성 분석)

  • Mun, Seong Woo;Kang, Young Seok;Kim, Ji Sun;Hwang, Ga-Hyun;Park, Ju Hyun;Lee, Sun Myung;Jeong, Hye Young
    • Journal of Conservation Science
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    • v.36 no.6
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    • pp.533-540
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    • 2020
  • Mt. Neoseongsan (NSS) is the only natural Neorok source in Korea. The geological, historical, and cultural values of NSS were recognized in 2013, and NSS has since been designated and maintained as a natural monument (No. 547), which has restricted the research and utilization of NSS Neorok. The limited NSS Neorok supply has hindered the restoration research of traditional pigments. Recently, a large amount of Neorok has been mined from Mt. Gwangeongsan (GJS) and is expected to be the main supply source of Neorok for restoring traditional pigments. Therefore, this study analyzed the characteristics of NSS- and GJS-Neorok-based pigments to evaluate the feasibility of substituting GJS Neorok for NSS Neorok in pigments. The NSS Neorok was mostly comprised of celadonite, whereas the GJS Neorok included minerals containing glassy phases such as celadonite, cristobalite, tridymite, etc. Because both Neorok samples were vitrified under identical conditions, the GJS Neorok grains were larger than the NSS Neorok ones. The GJS Neorok pigment showed that the chromaticity, grain size, oil absorption, and stability varied depending on the mineral types and contents. In particular, GJS-2 and NSS Neorok showed similar mineral compositions, physical properties, and stabilities, suggesting that GJS-2 can be substituted for NSS Neorok, which has been difficult to source and utilize ever since NSS was designated as a natural monument.

Effect of Naeso-san on Gastric Motility between Normal Intact and Antral Dilatated Rats (내소산(內消散)의 정상 및 위 유문부 확장 흰 쥐의 위 운동성에 대한 효능)

  • Kim, Jin-Seok;Yoon, Sang-Hyub
    • The Journal of Internal Korean Medicine
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    • v.29 no.1
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    • pp.117-129
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    • 2008
  • Background & Objective : Naeso-san(NSS) has been used for the treatment of functional dyspepsia, regarded as a gastric dysmotility disease. A main cause of gastric dysmotility is antral dilatation or antroduodenal uncoordination. Therefore, we investigated the effect of NSS on gastric motility and its mechanism of action, as well as the morphologic changes in antral dilatated rats. Methods : Antral dilatated rats were induced by wrapping a nonabsorbable rubber ring(D:6mm, W:4mm, T:1mm) around the 1st portion of the duodenum for 8 weeks. Then morphologic changes were investigated and compared with normal intact rats before and after 8 weeks. Gastric emptying was measured by administration of normal saline(NS) or NSS in normal intact and antral dilatated rats. In another series of experiments to evaluate the mechanism of NSS under delayed conditions, normal intact rats were treated with atropine sulfate(1mg/kg, s.c.), quinpirole HCl(0.3mg/kg, i.p.), $NAME(N^{G}-nitro-L-arginine$ methyl ester, 75mg/kg, s.c.) and cisplatin(10mg/kg, i.p.), respectively. The myoelectrical activity of the gastric smooth muscle was recorded in normal intact and antral dilatated rats. The contractile waves were measured for 30 minutes before and after administration of each solution(NS, NSS). Results : Body weight gain of antral dilatated rats was significantly lower than that of the controls. Futhermore, we found the thickness of the mucosal and muscular layers and surface area of the stomach increased significantly compared with controls. NSS 278㎎/㎏ improved gastric emptying more than normal saline or NSS 93mg/kg in normal intact(p=0.026) and antral dilatated rats(p=0.03). NSS enhanced gastric emptying significantly in the NAME treated group(p=0.002). NSS 278mg/kg increased the significant postprandial dominant power than that of NS in normal intact rats, whereas there was no statistical significance in antral dilatated rats. Conclusions : NSS stimulates gastric motility through the cholinergic pathway. We expect that pathologic model with antral dilatation can be used as an exprimental tool which is similar to dyspepsia and NSS would be effective especially in dysmotility-like functional dyspepsia with antral dilatation or impaired reservoir functions such as gastric adaptive relaxation.

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An Analysis on Micro-climate Characteristic of Apartments in Beijing, China Using ENVI-met Simulation (ENVI-met를 이용한 중국 베이징 아파트 하절기 미기후 특성 분석)

  • Wu, Jin-Dong;Lee, Jun-Hoo;Yoon, Seong-Hwan
    • Journal of the Architectural Institute of Korea Structure & Construction
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    • v.35 no.8
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    • pp.169-176
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    • 2019
  • The purpose of this study was to analyze outdoor thermal comfort of apartments planning characteristic of pedestrian height in Beijing, China. Selecting 322 apartment complexes with more than 1000 households and more than 10 buildings(including 10 buildings), mainly in Chaoyang District and Tongzhou District to select 32 basic layout types and then 12 typical layout types were select in 32 basic layout types. Finally, the simulation was conducted for the 12 typical layout types using the micro-climate model ENVI-met to evaluate the wind environment, the thermal environment and the comfort. The results of this study as follows: In the parallel arrangement, it has the best outdoor thermal comfort of Slab-East-Parallel(S/E/P). Next is Slab-South-Parallel(S/S/P), Tower-South-Parallel(T/S/P) in turn. In the stagger arrangement, Mixture-South-North and South Stagger-1(M/S/NSS-1) has the best outdoor thermal comfort and Slab-South-North and South Stagger(S/S/NSS), Tower-South-North and South Stagger(T/S/NSS), Mixture-South-North and South Stagger-3(M/S/NSS-3), Mixture-South-North and South Stagger-4(M/S/NSS-4), Mixture-South-North and South Stagger-2(M/S/NSS-2) in turn. In the cluster arrangement, Mixture-Mixture-Cluster-2(M/M/C-2) has the best outdoor thermal comfort and Mixture-Mixture-Cluster-3(M/M/C-3), Mixture-Mixture-Cluster-1(M/M/C-1) in turn. Due to the low wind speed and high air temperature, it is necessary to consider the layout types that can form the wind road at first, such as Mixture-South-North and South Stagger-1(M/S/NSS-1), Slab-South-North and South Stagger(S/S/NSS) and so on.