• Title/Summary/Keyword: Natural frequency

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The radioprotective effects of Bu-Zhong-Yi-Qi-Tang and its major ingredients in irradiated mice (방사선 피폭 마우스에서 보중익기탕 및 구성단미의 효과)

  • Kim, Sung-ho;Oh, Heon;Kim, Se-ra;Jo, Sung-kee;Byun, Myung-woo;Shin, Dong-ho
    • Korean Journal of Veterinary Research
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    • v.40 no.2
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    • pp.221-228
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    • 2000
  • We performed this study to determine the effect of Bu-Zhong-Yi-Qi-Tang, as a prescription of traditional Oriental medicine, and its major ingredients on jejunal crypt survival, endogenous spleen colony formation, apopotosis in jejunal crypt cells, lethality and hematological change of mice irradiated with high and low dose of Y-radiation. Bu-Zhong-Yi-Qi-Tang administration before irradiation protected the jejunal crypts (p<0.0001), increased the formation of endogenous spleen colony (p<0.05) and reduced the frequency of radiation-induced apoptosis (p<0.05). The survival rate and mean survival time of the groups treated with Bu-Zhong-Yi-Qi-Tang within 30 days after the treatment were far better than the irradiation control group. In the experiment on the effect of ingredients of Bu-Zhong-Yi-Qi-Tang, the result indicated that the extract of Rensan (Panax ginseng), Danggui (Angelica sinensis), Shengma (Cimicifuga heracleifolia) and Chaihu (Bupleurum falcatnosa) might have a major radioprotective effect. Although the mechanisms of this inhibitory effect remain to be elucidated, these results indicated that BU-Zhong-Yi-Qi-Tang might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the protective nature of Bu-Zhong-Yi-Qi-Tang extract and its ingredients.

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Relationship between BMI and the Dining Out Behavior of University Students in the Seoul Area (대학생들의 BMI 지수에 따른 외식 식행동 - 서울지역을 중심으로)

  • Kim, Mee-Jeong
    • Korean journal of food and cookery science
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    • v.26 no.4
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    • pp.450-457
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    • 2010
  • A survey was conducted to determine the relationship between BMI and the dining out behaviors of 316 university students in Seoul area for May and September, 2006. The subjects included 114 males and 202 females. General characteristics and BMI determined that of the students 56 (17.7%) were underweight, 222 (70.3%)were normal, 23 (7.3%) were overweight, and 15 (4.7%) were obese. There were differences in BMI according to age, sex, and major. Students majoring in natural science and engineering were 58.3% and 51% normal weight, respectively, and the next most common weight class was overweight. The non smoking group showed had primarily normal weight subjects followed by underweight-subjects, but the smoking group had primarily normal weight subjects followed by overweight subjects (P<0.001). The frequency of dining out for breakfast significantly correlated with BMI (P<0.05). The group that frequently dined out for breakfast were primarily of normal weight followed by overweight subjects, but the group that rarely dined out for breakfast were primarily of normal weight followed by underweight subjects(21.4%). Groups whose criteria for selecting dining out meals were flavor and price showed a higher percentage of underweight subjects than other groups. The group whose motivations for choosing dining out meals were convenience and habit showed a higher percentage underweight subjects than other motivations. The group that selected the Western food menu for dining out showed a higher percentage of underweight subjects than other food menu groups. And, the groups that selected Japanese and Korean food were primarily of normal weight followed by underweight subjects, but the result was not significant.

A study on the characteristics of female shoes in 2000's (여성구두의 디자인 특성에 관한 연구 -2000년대를 중심으로-)

  • Chae, Min-Jung;Koo, Kyo-Jong;Chae, Jin-Mee
    • Korean Journal of Human Ecology
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    • v.17 no.5
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    • pp.975-987
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    • 2008
  • The purpose of this thesis is to conduct a thorough research on shoes of 2000s, understand the changes and analyze the differences and the characteristics of the shoe designs of the past and present in order to predict and indicate the future direction of the women shoe designs. The shoes of the millennium not only kept the old fashioned shapes but also showed futuristic shapes. With the increasing importance of shoes in fashion, shoes with various images were created. As far as the materials are concerned, natural materials and artificial materials were both used. The colors were vivid and the futuristic colors. On the other hand, pastel toned colors and romantic colors were used in many different designs and shapes regardlees of the seasons. Straps and hills differed from the oldies. Heavy decorations were added to strap shoes to form a whole new design and hills show geometrical platforms or the avantgarde like heights. Feminine images overwhelmed the shoe designs of the millennium. To elaborate, Pumps displayed feminine images the most for it showed a high frequency number regardless of the seasons. Shoes are presented in aesthetical perspective rather then functional or practical perspectives that are based on human nature. Cultural, social, environmental and some part religious factors had a great influence on the evolution on the shoes. Especially in the 2000s, future oriented concepts were implemented on shoe designs, resulting a wider range of expressiveness and in the end leading to a more creative shoe designing. Changes in shoe designs could be pointed out in many ways according to the shapes materials, colors, modeling of decorations or also with the diverting trends.

Development of a Genome-Wide Random Mutagenesis System Using Proofreading-Deficient DNA Polymerase ${\delta}$ in the Methylotrophic Yeast Hansenula polymorpha

  • Kim, Oh Cheol;Kim, Sang-Yoon;Hwang, Dong Hyeon;Oh, Doo-Byoung;Kang, Hyun Ah;Kwon, Ohsuk
    • Journal of Microbiology and Biotechnology
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    • v.23 no.3
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    • pp.304-312
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    • 2013
  • The thermotolerant methylotrophic yeast Hansenula polymorpha is attracting interest as a potential strain for the production of recombinant proteins and biofuels. However, only limited numbers of genome engineering tools are currently available for H. polymorpha. In the present study, we identified the HpPOL3 gene encoding the catalytic subunit of DNA polymerase ${\delta}$ of H. polymorpha and mutated the sequence encoding conserved amino acid residues that are important for its proofreading 3'${\rightarrow}$5' exonuclease activity. The resulting $HpPOL3^*$ gene encoding the error-prone proofreading-deficient DNA polymerase ${\delta}$ was cloned under a methanol oxidase promoter to construct the mutator plasmid pHIF8, which also contains additional elements for site-specific chromosomal integration, selection, and excision. In a H. polymorpha mutator strain chromosomally integrated with pHIF8, a $URA3^-$ mutant resistant to 5-fluoroorotic acid was generated at a 50-fold higher frequency than in the wild-type strain, due to the dominant negative expression of $HpPOL3^*$. Moreover, after obtaining the desired mutant, the mutator allele was readily removed from the chromosome by homologous recombination to avoid the uncontrolled accumulation of additional mutations. Our mutator system, which depends on the accumulation of random mutations that are incorporated during DNA replication, will be useful to generate strains with mutant phenotypes, especially those related to unknown or multiple genes on the chromosome.

Population Dynamics of Crangon hakodatei from Coastal Area of Geoje Island, Korea (거제도 연안에 서식하는 마루자주새우, Crangon hakodatei의 개체군 역학)

  • Choi Jung Hwa;Kim Jung Nyun;Kim Sung Tae;Cha Hyung Kee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.35 no.4
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    • pp.380-385
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    • 2002
  • The sand shrimp, Crangon hakodatei commonly occured in the southern coast of Korea. The population structure, growth, mortality, and size at sexual maturity of C. hakodatei were examined by the samples collected from the coastal area of Geoje Island, Korea from October 2000 to October 2001. For estimation of parameters of growth and mortality, monthly length-frequency data were analysed by ELEFAN. Parameters of growth were estimated, using the modified yon Bertalanffy growth function model. The female grew faster and reached larger size at the same age than the male, There was a breeding season showing a peak in winter (January to february). Total mortality by length-converted catch curve was estimated at $3.10 yr^{-1}$, fishing mortality was $0.62 y^{-1}$ and natural mortality was $2.48 yr^{-1}$. The size at $50\%$ sexual maturity for the female ranged from CL 11.00 to 11.50 mm.

Protective Effects of a Herb, Menthae Herba, against Radiation-induced Oxidative DNA Damage

  • Jo, Sung-Kee;H, Heon-O;Uhee Jung;Kim, Sung-Ho;Byun, Myung-Woo
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.152-152
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    • 2003
  • As utilization of radiation in medicine, industry and biochemical research increases, the protection against radiation damage has become an important issue. Natural products such as herbal medicines are beginning to receive attention as modifiers on the radiation response. In the present study, the protective effect of a herb, Menthae Herba, against radiation-induced DNA damage was evaluated using alkaline single-cell gel electrophoresis (SCGE; comet assay) in the mouse peripheral blood Iymphocytes and the micronucleus formation test in the Chinese hamster ovary (CHO) cells. The tail moment, which was a marker of DNA damage in the SCGE, and the frequency of micronuclei was decreased in groups treated with Mentae Herba extract before exposure to 200 cGy of gamma-ray. We also confirmed its activities to scavenge DPPH and hydroxyl radicals. These experiments demonstrated that Menthae Herba was effective at reducing the radiation-induced damage of DNA and scavenging free radicals. It is plausible that scavenging of free radicals by Menthae Herba may have played an important role in providing the protection against the radiation-induced damage to the DNA. These results indicated that Menthae Herba might be a useful radioprotector and that radical scavenging appears to be one of the mechanisms of radiation protection.

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Phylogenetic Analysis by RFLP and Sequencing of Mitochondrial DNA in a Korean Population

  • Lee, Jin-Young;Kim, Heui-Soo;Ha, Bae-Jin;Park, Yeong-Hong
    • Archives of Pharmacal Research
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    • v.29 no.1
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    • pp.88-95
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    • 2006
  • Analysis of molecular nature of mitochondrial DNA (mtDNA) could be powerful marker for anthropological studies of modern populations. While population genetic studies on mtDNA have been reported for several ethnic groups, no such study has been documented for the Korean population. We surveyed mtDNA polymorphisms in the HVS I of noncoding D-loop region and its upstream region from 430 unrelated healthy Korean population by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and direct sequencing analysis. PCR product with 2,790 bp spanning the specific mtDNA region (mt13715-16504) was subjected to RFLP analysis using 6 restriction enzyme (Hinf I, Hae III, Alu I, Dde I, Mbo I, Rsa I). On the PAUP analysis of PCR-RFLP results, 38 mtDNA haplotypes (Hap 1-38) were detected in the Korean populations, which were classified into 11 haplogroups (Grp 1-11) of related haplotypes encompassing all 38 haplotypes. In comparison of sequencing data with Anderson's reference sequence, the transition type was more prevalent than the transversion type. Insertions or deletions were not found. In addition, three of the polymorphic sites (A16240C, A16351G, G16384A) in HVS-I region are determined newly. The polymorphic sites were distributed randomly in the region, though the frequency at each site was variable. Thus, this research might be required for the genealogical study of Orientals.

Pollination Mechanism of Bupleurum latissimum (Apiaceae) (멸종위기종인 섬시호(Bupleurum latissimum, 산형과)의 수분기작)

  • So, Soonku;Han, Kyeongsuk;Kim, Muyeol;Park, Hyerim;Seo, Eunkyoung;Kim, Yang-Pyo;Kim, Tae-Heung
    • Korean Journal of Plant Taxonomy
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    • v.38 no.1
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    • pp.43-50
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    • 2008
  • The pollination system of Bupleurum latissimum Nakai (Apiaceae) was investigated in the natural population of Korea. The various insects of 19 species, 11 families, 5 orders visited the flowers of B. latissimum. Episyrphus balteatus and Lasioglossum occidens were considered as the most effective pollen vector which have associated specially with B. latissimum. The visitation frequency peaked at 10 AM - 13 PM and no visitor was recognized during night time. The flowers of B. latissimum last during only three days and they are protandry. It is also confirmed that the flower of B. latissimum is self-compatible and cross-pollination by vectors is critical for successful seed setting.

Analysis of Dynamic Behavior of Railway Bridge with Concrete Track (콘크리트궤도 부설 철도교량의 동적거동 분석)

  • Min, Rak-Ki;Sung, Deok-Yong;Park, Yong-Gul
    • Journal of the Korean Society for Railway
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    • v.15 no.2
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    • pp.147-153
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    • 2012
  • Precise estimation f a structure's dynamic characteristics is indispensable for ensuring stable dynamic response during life time especially for the structures which can experience resonance such as railway bridges. Especially, concrete track can change the modal properties of the railway bridge, through the contribution of stiffness as well as mass effects, generally only the mass effect is considered in dynamic analysis of the railway bridge. In this paper, static and dynamic behaviors of railway bridge with concrete track were investigated through experimental study. Also, numerical analysis was performed about considering only mass of concrete track and together with stiffness and mass of concrete track. These were compared with experiment value. Numerical analysis value considering together with stiffness and mass of concrete track was similar experiment value. Therefore, when dynamic analysis of railway bridge with concrete track is performed, the contribution of stiffness as well as mass effects for concrete track is considered.

The Synoptic Characteristics of Heavy Rain in South Korea (한반도 집중호우의 종관적 특성)

  • Jeong, Goan-Young;Ryu, Chan-Su
    • Journal of the Chosun Natural Science
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    • v.1 no.2
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    • pp.89-114
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    • 2008
  • Interrelationship between heavy rainfalls and related with low-level jets(LLJ) is analyzed by using fifty cases of heavy rainfall events occurred over the Korean peninsula from 1992 to 2001. Those cases are classified with four synoptical features. There are 32% chances that the low pressure exist in heavy rainfall over than 150 mm per day case by case. Secondly Changma front and front zone account for 28% of all cases. The ratio of marine tropical boundary type and trough type record 22% and 18% respectively. The moist and warm south-westerly winds associated with low-level jets have been induced convective instability and baroclinic instability. Therefore, heavy rainfall due to the approach of a low pressure occurred at September and before Changma. During the period of Changma, this type has been happened heavy rainfall when low pressure and stationary front has vibrated south and north. Changma type has longer the duration time of precipitation than other types. Third type, located with marine Tropical boundary, have mainly rained in August and September. The last trough case locally downpoured in short time with developing cell. The occurrence low-level jets related to heavy rainfall has increased over 12.5 m/s wind speed. The result is that 43 heavy rainfalls out of 50 cases reach peak at the time of maximum precipitation intensity. Also, the variation of wet number and K-index corresponded with the variation of wind speed. It is found that the number of frequency of low-level jets with southwestward direction has been increased and these jets are mainly passed from the southwest toward to the northeast of the Korean peninsula in that time.

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