• Journal of the Korean Applied Science and Technology
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• v.38 no.3
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• pp.629-637
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• 2021

To develop a safer cosmetic preservative, we carried out a comparative study on characteristics of OD and OD-gal, where OD-gal was synthesized from OD using E. coli β-gal. OD-gal synthesis was confirmed by mass spectrometry analysis as sodium adduct ion (m/z=331.1731) and protonated ion (m/z=309.1926) of OD-gal. To compare the antimicrobial activities of OD and newly synthesized OD-gal, MIC values were investigated using E. coli, S. aureus, C. albicans, and A. niger. As a result, it was observed that there was no remarkable difference between MIC values of OD and OD-gal. In addition, to compare the cytotoxicity of OD-gal and OD, HaCaT cells were treated with OD or OD-gal, and then cell viability was quantified using EZ-Cytox assay. In the case of 1.5% OD, the cell viability was 64% at 24 h and 42% at 48 h compared to the control, and cell viability of 1.5% OD-gal-treated cells showed no significant change at 24 h and was 85% at 48 h. Consequently, the cytotoxicity of OD-gal-treated cells was reduced by more than 40% when compared with that of OD-treated cells. Thus, the newly synthesized OD-gal in this study is safer than the existing OD used as a cosmetic additive. In the future, OD-gal will be applicable as a substitute for OD as a less toxic preservative for the cosmetic industry.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.7
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• pp.981-988
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• 2001

Characteristics of evaporation heat transfer in 6.2 and 5.1mm OD micro-fin tubes were investigated in the present study. The data were taken at evaporation temperatures of -5$^{\circ}C$ and 5$^{\circ}C$ and heat fluxes 5kW/$m^2$ to 10kW/$m^2$. Mass flux was consequently maintained at 210, 300 and 410kg/$m^2$s for the 6.2mm OD tube and 465, 500 and 600kg/$m^2$s for the 5.1mm OD tube. The effects of heat flux, mass flux, and outer diameter on the heat transfer coefficient are explored in the present study. The data showed that the evaporation heat transfer coefficient for the 6.2mm OD tube was averagly higher by 16% than that for a 7.0mm OD tube, while the 5.1mm OD tube had approximately 30% higher value than the 6.2mm OD tube.

• Journal of Korean Society of Transportation
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• v.23 no.7 s.85
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• pp.125-136
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• 2005

The goal of this paper is to develop freeway Origin-Destination (OD) demand estimation model using VDS and AVI data. The formulation of methodology proposed in this paper includes traffic flow technique to be able to remove the bi-level problem and optimal solution algorithm using a kalman filter algorithm. The proposed dynamic OD estimation model use ilk and off-ramp volumes collected from VDS and partial OD collected from AVI data to raise the accuracy of dynamic OD estimation. The proposed model is evaluated by using the real-time data of SOHAEAN freeway, South Korea. The result of the proposed dynamic OD estimation model based on VDS and AVI data is better than that of based on VDS data. The more AVI systems are equipped at on and off-ramp, the more excellent result of estimation accuracy is expected.

• Journal of Information Technology Services
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• v.11 no.sup
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• pp.177-189
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• 2012

We developed the ocean disaster detection system(OD2S) which copes with the occurrences of ocean disasters (e. g. the red and green tide, the oil spill, the typhoon, and the sea ice) by converging and integrating the ocean color remote sensing using the satellite and the information technology exploiting the mass data processing and the pattern recognitions. This system which is based on the cosine similarity detects the ocean disasters in real time. The existing ocean color sensors which are operated in the polar orbit platforms cannot conduct the real time observation of ocean environments because they support the low temporal resolutions of one observation a day. However, geostationary ocean color imager(GOCI), the first geostationary ocean color sensor in the world, produces the ocean color images(e. g. the chlorophyll, the colored dissolved organic matter(CDOM), and the total suspended solid(TSS)), with high temporal resolutions of hourly intervals up to eight observations a day. The evaluation demonstrated that the OD2S can detect the excessive concentration of chlorophyll, CDOM, and TSS. Based on these results, it is expected that OD2S detects the ocean disasters in real time.

• Korean Journal of Plant Resources
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• v.36 no.6
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• pp.556-561
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• 2023

Oldenlandia diffusa (OD), a member of the Rubiaceae family, has been used for treating inflammatory and infectious diseases. However, the anti-atopic effects of OD are not completely understood yet. Thus, the aim of the present study was to elucidate beneficial effects of OD on atopic dermatitis (AD) in vivo. We examined the pharmacological effects of OD on compound 48/80- or histamine-induced scratching behaviors and 2, 4-dinitrochlrobenzene (DNCB)-induced AD-like skin lesions in mice. Additionally, we evaluated regulatory effects of OD on the expression of interleukin (IL)-6 and tumor necrosis factor (TNF)-α in DNCB-induced AD-like skin lesions. Results showed that OD inhibited the scratching behavior and AD symptoms. It also decreased serum levels of IgE and histamine in mice. Moreover, OD significantly ameliorated the expression of IL-6 and TNF-α in AD-like skin lesion. These finding suggest experimental evidence of that OD's potential for treating AD.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.3D
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• pp.355-361
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• 2011

In order to properly evaluate ITS services exposed in SMART Highway project, a confident dynamic origin-destination (OD) is inevitably needed. This paper used WAVE communication information as a part of call and response (C&R) communication which constitutes core part of the technology for constructing OD. This information includes node information and vehicle information (e.g., latitude and longitude) as well as trajectory data and sample path volume date calculated using node information and vehicle information. A procedure developed to construct a dynamic OD and to validate OD is consist of 1) making toy network and one-hour 00 (random distribution), 2) collecting link information and vehicle information, 3) constructing five-minute OD, and 4) validating estimated OD result using traffic volume and travel time simultaneously. The constructed OD is about 84.79% correct within less than 20% error range for 15min traffic volume, and about 85.42%, within less than 20% error rate of 15 min travel time. Some limitations and future research agenda have also been discussed.

• KSBB Journal
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• v.8 no.5
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• pp.424-430
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• 1993

The anti-stress effect by the treatment of vitamin C was investigated in this study. The treatment of ascorbic acid in the presence of $Cu^{2+}$ion induced strong time- and dose-dependent degradation of hitamine, and also the addition of histamine accelerated time-dependent decomposition of ascorbic acid in vitro. The treatment of ascorbic acid in $ODS^{od}/_{od}$rats, which cannot synthesize ascorbic acid, significantly decreased the urinary histamine. The protreatment of ascorbic acid, dexamethasone and promethazine inhibited the lethal effect induced by immobilization stress, but that of dimethylsulfoxide did not. The addition of ascorbic and to a culture of spleen cells of $ODS^{od}/_{od}$rats significantly increased the Con A-dependent T lymphocyte proliferation.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.9
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• pp.1269-1275
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• 2012

An experiment was conducted to study the effect of soluble protein supplements on concentration of soluble non-ammonia nitrogen (SNAN) in the liquid phase of ruminal (RD) and omasal digesta (OD) of Korean native steers, and to investigate diurnal pattern in SNAN concentration in RD and OD. Three ruminally cannulated Korean native steers in a $3{\times}3$ Latin square design consumed a basal diet of rice straw and corn-based concentrate (control), and that supplemented (kg/d DM basis) with intact casein (0.24; IC) or acid hydrolyzed casein (0.46; AHC). Ruminal digesta was sampled using a vacuum pump, whereas OD was collected using an omasal sampling system at 2.0 h intervals after a morning feeding. The SNAN fractions (free amino acid (AA), peptide and soluble protein) in RD and OD were assessed using the ninhydrin assay. Concentrations of free AA and total SNAN in RD were significantly (p<0.05) lower than those in OD. Although free AA concentration was relatively high, mean peptide was quantitatively the most important fraction of total SNAN in both RD and OD, indicating that degradation of peptide to AA rather than hydrolysis of soluble protein to peptide or deamination may be the most limiting step in rumen proteolysis of Korean native steers. Diurnal variation in peptide concentration in OD for the soluble protein supplemented diets during the feeding cycle peaked 2 h post-feeding and decreased thereafter whereas that for the control was relatively constant during the entire feeding cycle. Diurnal variation in peptide concentration was rather similar between RD and OD.

• ETRI Journal
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• v.27 no.3
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• pp.319-325
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• 2005

In this paper the effect of temperature on the electrical properties of organic semiconductor disperse orange dye 25 (OD) have been examined. Thin films of OD have been deposited on $In_{2}O_{3}$ substrates using a centrifugal machine. DC current-voltage (I-V) characteristics of the fabricated devices $(Al/OD/In_{2}O_{3)$ have been evaluated at varying temperatures ranging from 40 to $60^{\circ}C$. A rectification behavior in these devices has been observed such that the rectifying ratio increases as a function of temperature. I-V characteristics observed in $Al/OD/In_{2}O_{3)$ devices have been classified as low temperature $({\leq} 50^{\circ}C)$ and high temperature characteristics (approximately $60^{\circ}C$). Low temperature characteristics have been explained on the basis of the charge transport mechanism associated with free carriers available in OD, whereas high temperature characteristics have been explained on the basis of the trapped space-charge-limited current. Different electrical parameters such as traps factor, free carrier density, trapped carrier density, trap density of states, and effective mobility have been determined from the observed temperature dependent I-V characteristics. It has been shown that the traps factor, effective mobility, and free carrier density increase with increasing values of temperature, whilst no significant change has been observed in the trap density of states.

• Restorative Dentistry and Endodontics
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• v.29 no.4
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• pp.399-408
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• 2004

Odontoblasts are responsible for the formation and maintenance of dentin. They are known to synthesize unique gene products including dentin sialophosphoprotein (DSPP). Another unique genes of the cells remain unclear. OD314 was isolated from the odontoblasts/pulp cells of rats and partially characterized as an odontoblast-enriched gene (Dey et al., 2001). This study aimed to elucidate the biological function of OD314, relating to odontoblast differentiation and dentinogenesis. After determining the open reading frame (ORP) of OD314 by transient transfection analysis using green fluorescent protein (GPP) expression vector, mRNA in-situ hybridization, immunohistochemistry, reverse transcription-polymerase chain reaction (RT-PCR) and western analysis were performed. The results were as follows: 1. In in-situ hybridization, OD314 mRNAs were expressed in odontoblasts of developing coronal and root pulp. 2. OD314 was a novel protein encoding 154 amino acids, and the protein was mainly expressed in cytoplasm by transient transfection analysis. 3. Mineralized nodules were associated with multilayer cell nodules in the culture of human dental pulp cells and first detected from day 21 using alizarin-red S staining. 4. In RT-PCR analysis, OD314, osteocalcin (OC) and DSPP strongly expressed throughout 28 days of culture. Whereas, osteonectin (ON) mRNA expression stayed low up to day 14, and then gradually decreased from day 21. 5. Western blots showed an approximately 17 kDa band. OD314 protein was expressed from the start of culture and then increased greatly from day 21. In conclusion, OD314 is considered as an odontoblast-enriched gene and may play important roles in odontoblast differentiation and dentin mineralization.