• Korean Journal of Agricultural Science
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• v.28 no.1
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• pp.33-40
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• 2001

The authors attempted to derive a comprehensive quantitative structure-toxicity relationships (QSTRs) between various physicochemical parameters of phenyl substituents in fungicidal phenylthionocarbamate derivatives and toxicity evaluated using TOPKAT calculation. On the basis of this approach we made preditions for toxicity values for not yet tested substances with respect to these systems. The results suggested that the optimal values, $(B_2)_{opt.}=1.54_{\AA}$(Ames mutagenicity), $(R)_{opt.}=0.16$ (car-cinogenicity of male rat), $(\pi)_{opt.)=0.16$ (carcinogenicity of male mouse), $({\varepsilon}LOMO)_{opt}=-0.52e.v.$ ($LD_{50}$ of rat oral), $(B_3){opt.}=1.54_{\AA}$(chronic LOAEU), $(logP)_{opt.}=4.25$ ($LC_{50}$ of Fathead minnow) and $({\sigma})_{opt}=-0.68$ ($EC_{50}$ of Daphnia magna) of phenyl substituents were strongly correlated with the acute and chronic toxicities.

• Journal of Plant Biotechnology
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• v.37 no.4
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• pp.483-493
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• 2010

Knock-out of a gene by insertional mutagenesis is a direct way to address its function through the mutant phenotype. Among ca. 15,000 gene-trapped Ds insertion lines of rice, we identified one line from selected sensitive lines in highly salt stress. We conducted gene tagging by TAIL-PCR, and DNA gel blot analysis from salt sensitive mutant. A gene encoding an oligopeptide transporter (OPT family) homologue was disrupted by the insertion of a Ds transposon into the OsOPT10 gene that was located shot arm of chromosome 8. The OsOPT10 gene (NP_001062118.) has 6 exons and encodes a protein (752 aa) containing the OPT family domain. RT-PCR analysis showed that the expression of OsOPT10 gene was rapidly and strongly induced by stresses such as high-salinity (250 mM), osmotic, drought, $100\;{\mu}M$ ABA. The subcellular localization assay indicated that OsOPT10 was localized specifically in the plasma membrane. Overexpression of OsOPT10 in Arabidopsis thaliana and rice conferred tolerance of transgenic plants to salt stress. Further we found expression levels of some stress related genes were inhibited in OsOPT10 transgenic plants. These results suggested that OsOPT10 might play crucial but differential roles in plant responses to various abiotic stresses.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.22 no.52
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• pp.97-107
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• 1999

The asymmetric traveling salesman problem is a representative NP-Complete problem. Polynomial algorithm for this problem has not been yet found. So, many heuristic methods have been researched in this problem. We need heuristic methods that produce good answers for some larger problems in reasonable times. 3-opt is well known for the effective local-search heuristic method. It has been used in many applications of the asymmetric traveling salesman problem. This paper discusses 3-opt's properties and ineffective aspects and presents a highly effective heuristic method. 3-opt does not consider good arcs(shorter distance or little cost). This paper presents a fast heuritic algorithm compared with 3-opt by inserting good arcs and deleting related arcs later.

• The Journal of Industrial Distribution & Business
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• v.11 no.2
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• pp.49-59
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• 2020

Purpose: Online and social media and mobile shopping are increasing and companies are required to provide personal information in order to supplement the non-invasive characteristics of the channels. With the increased provision of personal information, consumers' personal and social concerns about the prevention of personal information infringement are also increasing, and in response, personal or opt-in marketing has emerged to compensate for reckless information abuse. Despite the background of this emergence, the existing prior studies are limited to ignoring the negative feelings of consumers in the real world, including only the net function and positive effect of the opt-in mail. Research design, data and methodology: The research framework was intended to utilize the impact of human marketing activities on consumer attitudes combined with positive and negative factors. Factors that positively affect attitudes toward permation marketing were presented, such as informality, and perceived risks were presented as negative impact factors. Also, based on previous prior research, the prior factors of opt-in marketing were to present the effect on purchase intent through the medium of attitude toward opt-in marketing. Results: In this study, we used the framework of a two factor theory to address positive and negative factors as a leading factor in the customer attitude toward opt-in mail advertising, and as a result, functionality and personalization have a positive effect on customer attitude and perceived risk have a negative impact on customer attitude. In addition, it was confirmed that the customer attitude formed this way affects the intention to purchase again. Conclusions: This study suggests that we have demonstrated that marketing, an opt-in marketing that has been recognized as part of marketing that is deployed after obtaining customer consent, has been applied without any other marketing methodology. E-mail advertising at this point also provides practical implications that the system safeguards are in place under an opt-in protocol or system, and that even if an e-mail advertisement is carried out, customers will need to look at the level of awareness about the risks, and suggests that they need to consider the customer's journey that could lead to purchase at the content level.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.15 no.4
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• pp.249-257
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• 2015

This paper introduces a heuristic algorithm to NP-hard travelling salesman problem. The proposed algorithm, in its bid to determine initial path, applies SW-DNN, DW-DNN, and DC-DNN, which are modified forms of the prevalent Double-sided Nearest Neighbor Search and searches the minimum value. As a part of its optimization process on the initial solution, it employs 2, 2.5, 3-opt of a local search k-opt on candidate delete edges and 4-opt on undeleted ones among them. When tested on TSP-1 of 26 European cities and TSP-2 of 49 U.S. cities, the proposed algorithm has successfully obtained optimal results in both, disproving the prevalent disbelief in the attainability of the optimal solution and making itself available as a general algorithm for the travelling salesman problem.

• Journal of the Korea Society of Computer and Information
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• v.17 no.10
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• pp.155-165
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• 2012

This paper suggests traveling salesman problem algorithm that have been unsolved problem with NP-Hard. The proposed algorithm is a heuristic with edge-swap method. The classical method finds the initial solution starts with first node and visits to mostly adjacent nodes then decides the traveling path. This paper selects minimum weight edge for each nodes, then perform Min-Min method that start from minimum weight edge among the selected edges and Min-Max method that starts from maximum weight edges among it. Then we decide tie initial solution to minimum path length between Min-Min and Min-Max method. To get the final optimal solution, we apply previous two-opt to initial solution. Also, we suggest extended 3-opt and 4-opt additionally. For the 7 actual experimental data, this algorithm can be get the optimal solutions of state-of-the-art with fast and correct.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1993.04a
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• pp.109-118
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• 1993

This paper describes the management of knowledge base and optimization models using knowledge-assisted optimization model formulation system UNIK-OPT (UNIfied Knowledge-OPTimization). We will illustrate UNIK-OPT with the case of production scheduling in refinery.

• The korean journal of orthodontics
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• v.21 no.3
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• pp.581-590
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• 1991

This study was carried out for the comparison of the head postures between mouth breathers and normal nasal breathers. For this purpose, a test group of 28 mouth breathers, between the ages of 8 to 12 years old and a control group of 25 nasal breathers were used. Following results were obtained after comparing the craniofacial and craniocervical angulations to the True Vertical line. 1. In the comparisions relating to the True Vertical Line, results were obtained using four items; NSL/VER, FH/VER, NL/VER, PMV/VER. Variations were observed in all the items and the craniofacial angulations in the mouth breathers group showed more superior position compared to the control group. 2. In the comparisions relating to the craniocervical angulations, results were obtained using four items; NSL/OPT, FH/OPT, NL/OPT, PMV/OPT. Variations between the two groups were observed only in the PMV/OPT item and the mouth breather group showed more craniocervical angulations compared to the control group.

• Journal of the Korea Society of Computer and Information
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• v.4 no.1
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• pp.54-61
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• 1999

The MRP, OPT and JIT systems have the respective limitations to become the suitable production management systems of the future. Therefore it is highly requested to develop an integrated production management system by the hybridization of those production systems. Accordingly, this study has focused its hybrid model using MRP, JIT and OPT. There has been many efforts in comparing and analyzing the usefulness and the limitations of those production systems and applying the usefulness to the maximum which improving and supplementing the weakpoints of respective systems. In this respect, this study develop the hybrid simulation model, and this hybrid model are evaluated and compared with MRP(Push system) and JIT(Pull system) by using a simulation.

• Journal of the Korea Society of Computer and Information
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• v.6 no.1
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• pp.95-102
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• 2001

Supply Chain Management drawing attention of business management all over the world. This study has simulated OPT(Optimized Production Technology) to verify the Supply Chain Management's effectiveness The OPT system develops a detailed operating Philosophy, not just an operating procedure, and it includes many of the features of the JIT system and additional benefits as well The important OPT concepts such as. transfer batch. manufacturing process batch and batch it self served as a Pivotal role in increasing the productivity in manufacturing when they were altered. In this respect, this study develop the OPT simulation model, and this OPT model are evaluated by using a simulation study. It has proved that the performances of OPT model are excellent.