• Title/Summary/Keyword: Occupational

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Changes of pulmonary function during 60 days of welding fume exposure period in SD rats

  • Sung, Jae-Hyuk;Park, Byung-Gil;Maeng, Seung-Hee;Kim, Soo-Jin;Chung, Yong-Hyun;Han, Jeong-Hee;Hyun, Jin-Suk;Song, Kyung-Seuk;Yu, Il-Je
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.10b
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    • pp.125-125
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    • 2003
  • Respiratory effects in full time welders include bronchitis, airway irritation, lung function changes, and lung fibrosis. Welder's pneumoconiosis has been generally determined to be benign and not associated with respiratory symptoms based on the absence of pulmonary function abnormalities in welders with marked radiographic abnormalities.(omitted)

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Oxidative DNA Damages and Its Repair Enzyme Acitivities in the SD rats by Repeated Inhalation Exposure to the Hexavalent Chromium

  • Seung-Hee Maeng;Il-Je Yu;Hyun-Young Kim;Cheol-Hong Lim;Jong-Yoon Lee;Kwon-seob Lee;Yong-Mook Lee;Ho-Keun Chung;Hai-Won Chung
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.151-151
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    • 2001
  • According to the epidemiological studies in chromium workers, hexavalent chromium is associated with the risk of lung cancer. Reactive oxygen species produced by hexavalent chromium exposure may play an important role in the carcinogenesis process. We measured one kind of oxidative DNA damages, 8-hydroxydeoxyguanosine (8-OHdG) and its repair activities as an indicators of cellular oxidative stress in rat lungs by the repeated inhalation exposure to sodium chromate.(omitted)

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MICRONUCLEI INDUCTION BY REPEATED INHALATION EXPOSURE TO THE 1,1-DICHLORO-1-FLUOROETHANE BUT NOT BY THE SINGLE PERITONEAL INJECTION

  • Maeng, Seung-Hee;Chung, Hai-Won;Kim, Hyun-Young;Lim, Cheol-Hong;Lee, Jong-Yoon;Chung, Yong-Hyun;Lee, Yong-Mook;Chung, Ho-Keun;Yu, Il-Je
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.179-179
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    • 2001
  • To investigate the genotoxic effect of 1, 1-dichloro-1-fluoroethane which was widely used as a cleaning solvent at the electronic part industry, the micronucleus frequencies were recorded by examining polychromatic erythrocytes in bone marrows of single i.p. injected mice at high doses and of the repeatedly inhaled rats for 13 weeks at relatively low concentrations.(omitted)

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1,1-Dichloro-1-fluoroethane Induces Micronuclei in Bone Marrow Cells by Repeated Inhalation Exposure but not by the Single Peritoneal Injection

  • Maeng, Seung-Hee;Kim, Hyun-Young;Lim, Cheol-Hong;Lee, Jong-Yoon;Lee, Yong-Mook;Chung, Ho-Keun;Chung, Hai-Won;Yu, Il-Je
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.150-150
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    • 2001
  • To investigate the genotoxic effect of 1, 1-dichloro-1-fluoroethane, which was widely used as a cleaning solvent at the electronic part industry, the micronucleus frequencies were recorded by examining polychromatic erythrocytes in bone marrows of the rodents exposed to it with different routes.(omitted)

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Achievements, Problems, and Future Direction of the Quality Control Program for Special Periodic Health Examination Agencies in Republic of Korea

  • Won, Yong Lim;Ko, Kyung Sun;Park, Jae Oh;Choi, Yoon jung;Lee, Hyeji;Sung, Jung-min;Lee, Mi-young
    • Safety and Health at Work
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    • v.10 no.1
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    • pp.125-129
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    • 2019
  • The ultimate goal of the quality control program for special periodic health examination agencies is to diagnose the health condition of a worker correctly, based on accurate examination and analysis skills, leading to protect the worker's health. The quality control program on three areas, chemical analysis for biological monitoring since 1995, and pneumoconiosis, audiometric testing since 1996, has contributed to improve the reliability of occupational health screenings by improving the issues including standardization of testing methods, tools, diagnostic opinions, and reliability of analysis for biological monitoring. It has contributed to improving the reliability of occupational health monitoring by rectifying the following issues associated with previous monitoring: absence of standardized testing methods, testing tools that are not upgraded, mismatching diagnostic opinions, and unreliable results of biological specimen analysis. Nevertheless, there are issues in need of further improvement such as lack of expertise or the use of inappropriate method for health examination, and passive and unwilling participation in the quality control. We suggested solutions to these problems for each area of quality control program. Above all, it is essential to provide active support for health examiners to develop their expertise, while encouraging all the health screening agencies, employers, and workers to develop the desire to improve the system and to maintain the relevance.