• Title/Summary/Keyword: Orthopaedics

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Turrets Exostosis with Swan Neck Deformity: An Unusual Occurrence

  • Mruthyunjaya, Mruthyunjaya;Nekkanti, Supreeth;Venkateshaiah, Sheshagiri;Siddartha, Arunodhaya;Thottimane, Pramod;Pimpale, Tushar
    • Archives of Hand and Microsurgery
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    • v.23 no.4
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    • pp.277-280
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    • 2018
  • Turrets exostosis are extremely rare to occur. Benign bony outgrowths from the dorsum of the phalanges following trauma are termed Turrets exostosis. We report an unusual case of Turrets exostosis of the fourth finger with no preceding trauma which has never been reported before. A 50-year-old female patient presented to us with a bony swelling on the dorsum of the fourth finger of her right hand in one year. The swelling was dormant initially and started to progress in size since three months leading to pain, restriction of movements and deformity of the finger. Turrets exostosis are very rare to occur. A preceding history of trauma is not necessary for it to occur as described in the literature. Surgical excision yields good results and is indicated when the bony mass causes a progressive deformity of the finger and restriction of movements of the finger.

Socket Pressure Distribution of the Uni-Lateral Trans-Femoral Amputee with a Suction Socket (흡착식 소켓을 착용한 일측 대퇴절단환자의 소켓내부압력분포)

  • Chang, Y.H.;Kim, Y.H.;Yang, G.T.;Lim, S.H.;Mun, M.S.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.249-252
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    • 1997
  • A study on static and dynamic socket pressure distributions on a trans-femoral amputee with a suction socket was performed in order to assess an optimal socket fitting and function. Even for the amputee's static neutral position, pressure concentrations were observed in the lateral, medial, and posterior planes of the socket. During free walking, a significant movement of pressure concentration areas was observed. Large socket pressure was observed in the lateral, medial-anterior and posterior walls during mid-stance or push-off period. Socket pressure measurement will be one of the good tool to determine the optimal socket-limb interface.

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Plantar-Pressure Distributions on Hallux Valgus Patients (엄지발가락외반증 환자의 발바닥압력분포)

  • Yang, G.T.;Kim, Y.H.;Park, Si-Bog;Lim, S.H.;Chang, Y.H.;Mun, M.S.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.241-244
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    • 1997
  • 23 hallux valgus patients were evaluated with clinical examinations and plantar pressure distribution measurements. A masking method for detailed plantar pressure distribution analyses was suggested. With higher grade of hallux valgus, pressure, contact length & area, and impulse on metartasus were significantly increased. Localized pressure concentration is very important in foot diseases and appropriate plantar pressure distributions should be considered on any shoe design.

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Chloroquine and Valproic Acid Combined Treatment in Vitro has Enhanced Cytotoxicity in an Osteosarcoma Cell Line

  • Wang, Chuan-Kun;Yu, Xi-Dong;Li, Qiang;Xie, Gang;Teng, Yue
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4651-4654
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    • 2013
  • Choroquine (CQ) and valproic acid (VPA) have been extensively studied for biological effects. Here, we focused on efficacy of combined CQ and VPA on osteosarcoma cell lines. Viability of osteosarcoma cell lines (U20S and HOS) was analyzed by MTT assay. Apoptotic assays and colony formation assays were also applied. ROS generation and Western Blotting were performed to determine the mechanism of CQ and VPA combination in the process of apoptosis. The viability of different osteosarcoma cell lines significantly decreased after CQ and VPA combination treatment compared with either drug used alone, and apoptosis was increased significantly. ROS generation was triggered leading to expression of apoptosis related genes being increased and of antiapoptotic related genes being decreased. From our data shown here, CQ and VPA combination treatment in vitro enhanced cytotoxicy to osteosarcoma cells.