• Title/Summary/Keyword: PFR

Search Result 66, Processing Time 0.03 seconds

A Possible Relation of the Helicobacter pylori pfr Gene to Iron Deficiency Anemia? (Helicobacter pylori 연관 철분 결핍성 빈혈과 H. pylori pfr 유전자 다형성과의 관련성)

  • Lee, Ji-Eun;Choe, Yon-Ho;Hwang, Tae-Sook
    • Pediatric Gastroenterology, Hepatology & Nutrition
    • /
    • v.4 no.1
    • /
    • pp.28-33
    • /
    • 2001
  • Purpose: H. pylori infection is thought to contribute to iron-deficiency anemia, especially during puberty. The ferritin protein Pfr of H. pylori is homologous to eukaryotic and prokaryotic ferritins. The purpose of this study was to analyze the H. pylori pfr status in gastric biopsy specimens according to clinical data, including antral gastritis with or without iron-deficiency anemia. Methods: A total of 26 H. pylori-positive patients aged from ten to 18 years were categorized into subgroups based on the presence or absence of iron-deficiency anemia. All of them had antral gastritis. Sixteen patients were proved to have iron-deficiency anemia by hematological study, two of which had a duodenal ulcer. The other ten patients showed normal hematological findings. DNA isolation was performed from each of the gastric biopsy specimens. PCR amplification of the pfr gene coding was done using two sets of primers. The pfr region, 501 bp, was generated by linking the sequences of the two PCR products. The nucleotide and protein sequences were compared between the pfr regions from Korean H. pylori strains and the NCTC 11638, 26695, and J99 strain, which were obtained from the Genbank. Sequence comparisons were also performed for the pfr regions between the iron-deficiency anemia (+) and (-) groups. Results: Analysis of the complete coding region of pfr gene revealed three sites of mutation. The Ser39Ala mutation was found in 100% (26/26), Gly111Asn in 26.9% (7/26), and Gly82Ser in 11.5% (3/26). There were no significant differences in the mutations of the pfr regions between the iron deficiency anemia (+) and (-) groups. Conclusion: The mutation in the pfr gene did not relate with the clinical phenotype, iron deficiency anemia. Further studies are needed on the aspects of host side or other complex factors to elucidate anemia. Further studies are needed on the aspects of host side or other complex factors to elucidate the mechanisms by which the H. pylori infection might lead to iron deficiency anemia.

  • PDF

Binding of 59 Kilodalton Phytochrome from Avena sativa to Liposomes and Cibacron Blue Dye (귀리로 부터 얻은 59 KD phytochrome의 liposome과 Cibacron Blue Dye와의 결합성질)

  • Hahn, Tae-Ryong
    • Applied Biological Chemistry
    • /
    • v.32 no.2
    • /
    • pp.126-131
    • /
    • 1989
  • Binding properties of the degraded 59kD phytochrome from etiolated Avena sativa seedlings to liposomes and Cibacron Blue dye were examined. In contrast with the native 124kD and partially degraded 118kD phytochromes, the farred light absorbing(Pfr) forms of the 59kD phytochrome binds to liposomes and Cibacron Blue dye via electrostatic interactions. Results indicate that the 59kD Pfr does not hold a hydrophobic surface which is exposed upon Pr to Pfr phototransformation of the 124 and 118kD phytochromes. Since a relatively extensive hydrophobic region is located in the chromophore bearing domain(59kD) of phytochrome(Hershey et al., Nuc. Acids Res., 13, 8543, 1986), the 55kD tryptic domain from the C-terminus plays an important role on the exposure of the hydrophobic area in the 118 and 124 Pfr to occur.

  • PDF

Development of a Pad Conditioning Method for ILD CMP using a High Pressure Micro Jet System

  • Lee, Hyo-Sang;DeNardis, Darren;Philipossian, Ara;Seike, Yoshiyuki;Takaoka, Mineo;Miyachi, Keiji;Doi, Toshiro
    • Transactions on Electrical and Electronic Materials
    • /
    • v.8 no.1
    • /
    • pp.26-31
    • /
    • 2007
  • The goal of this study is to determine if High Pressure Micro Jet (HPMJ) conditioning can be used as a substitute for, or in conjunction with, conventional diamond pad conditioning. Five conditioning methods were studied during which 50 ILD wafers were polished successively in a 100-mm scaled polisher and removal rate (RR), coefficient of friction (COF), pad flattening ratio (PFR) and scanning electron microscopy (SEM) measurements were obtained. Results indicated that PFR increased rapidly, and COF and removal rate decreased significantly, when conditioning was not employed. With diamond conditioning, both removal rate and COF were stable from wafer to wafer, and low PFR values were observed. SEM images indicated that clean grooves could be achieved by HPMJ pad conditioning, suggesting that HPMJ may have the potential to reduce micro scratches and defects caused by slurry abrasive particle residues inside grooves. Regardless of different pad conditioning methods, a linear correlation was observed between temperature, COF and removal rate, while an inverse relationship was seen between COF and PFR.

Performance Analysis with Various Amounts of Electrolyte in a Molten Carbonate Fuel Cell

  • Kim, Yu-Jeong;Kim, Tae-Kyun;Lee, Ki-Jeong;Lee, Choong-Gon
    • Journal of Electrochemical Science and Technology
    • /
    • v.7 no.3
    • /
    • pp.234-240
    • /
    • 2016
  • The effect of initial electrolyte loading (IEL) on cell performance in a coin-type molten carbonate fuel cell (MCFC) was investigated in this work. Since the material of MCFC depends on the manufacturer, optimisation requires experimental investigation. In total, four IEL values, 1.5, 2.0, 3.0, and 4.0 g, were used, corresponding to a pore filling ratio (PFR) of 38, 51, 77, and 102%, respectively. The cell performance with respect to the PFR was analysed via steady-state polarisation, step-chronopotentiomtery, and impedance methods. The electrochemical analyses revealed that internal resistance and overpotential of the cell decreased with increasing PFR, and a large overpotential was observed when the PFR was 102%, probably due to the flooding phenomenon. After operation, cross-section of the cell was analysed via surface analysis of SEM and EDS methods, and the remaining electrolyte was estimated by dissolution of the cell in 10 wt% acetic acid. A linear relationship between IEL and the weight reduction ratio by dissolution was obtained. Thus, the remaining amount of electrolyte could be measured after operation. The results of SEM and EDS showed that a PFR of 38 and 102% showed a lack and flooding of electrolytes at the cell, respectively, which led to a large overpotential. This work reports that MCFC performance is allowed only in the narrow range of PFR.

Anaerobic Organic Wastewater Treatment and Energy Regeneration by Utilizing E-PFR System (E-PER 반응기를 이용한 유기성 폐기물의 혐기성 처리와 재생에너지 생산에 관한 연구)

  • Kim, Burmshik;Choi, Hong-Bok;Lee, Jae-Ki;Park, Joo Hyung;Ji, Duk Gi;Choi, Eun-Ju
    • Journal of the Korea Organic Resources Recycling Association
    • /
    • v.16 no.2
    • /
    • pp.57-65
    • /
    • 2008
  • Wastewater containing strong organic matter is very difficult to treat by utilizing general sewage treatment plant. but the wastewater is adequate to generate biomass energy (bio-gas; methane gas) by utilizing anaerobic digestion. EcoDays Plug Flow Reactor (E-PFR), which was already proved as an excellent aerobic wastewater treatment reactor, was adapted for anaerobic food wastewater digestion. This research was performed to improve the efficiency of bio-gas production and to optimize anaerobic wastewater treatment system. Food wastewater from N food waste treatment plant was applied for the pilot scale experiments. The results indicated that the efficiency of anaerobic wastewater treatment and the volume of bio-gas were increased by applying E-PFR to anaerobic digestion. The structural characteristics of E-PFR can cause the high efficiency of anaerobic treatment processes. The unique structure of E-PFR is a diaphragm dividing vertical hydraulic multi-stages and the inversely protruded fluid transfer tubes on each diaphragm. The unique structure of E-PFR can make gas hold-up space at the top part of each stage in the reactor. Also, E-PFR can contain relatively high MLSS concentration in lower stage by vertical up-flow of wastewater. This hydraulic flow can cause high buffering capacity against shock load from the wastewater in the reactor, resulting in stable pH (7.0~8.0), relatively higher wastewater treatment efficiency, and larger volume of bio-gas generation. In addition, relatively longer solid retention time (SRT) in the reactor can increase organic matter degradation and bio-gas production efficiency. These characteristics in the reactor can be regarded as "ideal" anaerobic wastewater treatment conditions. Anaerobic wastewater treatment plant design factor can be assessed for having 70 % of methane gas content, and better bio-gas yielding and stable treatment efficiency based on the results of this research. For example, inner circulation with generated bio-gas in the reactor and better mixing conditions by improving fluid transfer tube structure can be used for achieving better bio-gas yielding efficiency. This research results can be used for acquiring better improved regenerated energy system.

  • PDF

Controllability of White Pitch and Compatibility of Micropolymer on PEO/Cofactor Retention System and PAM/Bentonite Retention System (PEO/cofactor 보류 시스템과 PAM/bentonite 보류 시스템에서의 micropolymer 상용성과 백색 점착성 이물질 제어 효과)

  • Jung, Chul-Hun;Lee, Jin-Ho;Park, Jong-Moon
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.44 no.6
    • /
    • pp.43-49
    • /
    • 2012
  • In this work, the non-ionic polyethylene oxide(PEO)/phenolic formaldehyde resin(PFR) retention system, which was less affected by furnish charge, was analyzed for possibility and effectiveness when using recycled stock. When the micropolymer was added at the PEO/PFR retention system and the PAM/bentonite retention system, performance of retention and drainage was improved. When the cationic micropolymer was added on the PEO/PFR retention system, the highest retention was achieved. The Polyacrylamide(PAM)/bentonite system induced flocculation of white pitch by electrostatic flocculation. On the other hand, the non-ionic PEO/PFR retention system induced less flocculation of white pitch than the PAM/bentonite retention system.

A study on Applicable to Advanced treatment of using Side Stream Plug-Flow Reactor (효과적 공간활용을 위한 Side Stream Plug-Flow Reactor를 이용한 하수 고도처리 공정 적용에 관한 연구)

  • Kim, samju;Hyun, InHwan;Dockko, Suk
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.22 no.3
    • /
    • pp.367-372
    • /
    • 2008
  • This study configured the conventional $A^2O$ (Anaerobic-Anoxic-Aerobic bioreactor) system which the fixed media immersed into the anoxic reactor(Named PFR system : Plug Flow Reactor) for evaluating the removal efficiency of nitrogen in the wastewater. The experimental equipment was a cylinder which was consist of 4 pleated PE Pipes(Length 330M, Diameter 100mm) including 2 rope shape media. As a result, the average effluent T-N removal efficiency of the conventional $A^2O$ system was 17.9, 40.3, 50.6, 44.6% in each mode, but the average effluent T-N removal efficiency of the PFR system could achieve 38.8, 57.1, 71.8, 65.4% in each mode. It indicated that the PFR system caused to the increasing of C/N ratio that effected to the increasing of the denitrification efficiency. Not only the effective T-N removal efficiency but also the controllable install space will give advantages for retrofitting of the wastewater treatment plant with the conventional treatment system to the PFR system.

A Study for Phoria and Positive Fusion Reverse on Vision Training of Convergence Insufficiency (폭주부족 피검사자의 시기능 훈련에 의한 양성융합여력 및 사위 변화에 관한 연구)

  • Lee, Chang-Sun;Kim, In-Su;Son, Jeong-Sik;Sung, Duk-Yong;Kim, Jaedo;Kim, Ki-Hong
    • Journal of Korean Ophthalmic Optics Society
    • /
    • v.13 no.1
    • /
    • pp.83-87
    • /
    • 2008
  • Purpose: This study was investigated for the effects of vision training on the phoria and positive fusion reverse (PFR) of patients with convergence insufficiency (C.I). Methods: Subjects were included 11 patients with CI of T Vision Center (5 patients with distance orthophoria, 6 patients with distance exophoria). The vision training of this study had been processed daily during an average of 2 months for each patients. Results: The result showed that after vision training, the phoria and PFR of CI patient were improved significantly than that before vision training (p<0.05) and when the groups were divided to the distance orthophoria convergence insufficiency (DOCI) group and distance exophoria convergence insufficiency (DE-CI) group, these improvements were proved similarly in the both groups. Conclusions: This study proved that vision training for patients with C.I was effective for the improvement of the phoria and PFR of these patients.

  • PDF

A Study on the Site Planning of an Apartment Complex for Improving the Outdoor and Indoor Air Quality (아파트의 실내외 공기질 향상을 위한 주동 배치 계획 연구)

  • Shin, Jee-Woong;Kim, Tae-Yeon;Lee, Kyung-Hoi
    • KIEAE Journal
    • /
    • v.4 no.3
    • /
    • pp.195-202
    • /
    • 2004
  • This study focuses on the impacts of apartment building arrangements on the outdoor and indoor air quality - the efficiency of natural ventilation in the outside/inside area of an apartment with consideration to the characteristics of an air flow in outside area depending on the types of the arrangements, the main direction of the wind, and the outside wind pressure on the building facade. As indices to evaluate the efficiency of natural ventilation, the concepts of "Age of Air" and "Purging Flow Rate(PFR)" were used in this study. As indices to classify the efficiency of indoor natural ventilation, the mean values of the wind pressure differences between the front and the back elevations of an apartment building were used. The research showed that the PFR of each apartment building arrangement ranges from 0.867 to 3.253. The "minus-shaped" arrangement showed the highest PFR, 2.306; the "zigzag-shaped" arrangement measured 1.889; the "angle-shaped" arrangement measured 1.465, and the "square-shaped" arrangement measured 1.241. Depending on the direction of the wind, the pressure differences range extremely, with variations from 170% to 2300%. Thus, the indoor natural ventilation efficiency can be changed by the pressure differences of the wind, which are sensitive to the main direction of the wind even though the structure and planning of the apartment complexes are the same. Despite the same direction of the wind, even the efficiency can be diverse. This study showed how to predict the most beneficial apartment building arrangement for the profitable natural ventilation efficiency in each direction of the wind.