• Journal of The Korean Society of Inherited Metabolic disease
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• v.21 no.1
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• pp.7-14
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• 2021

Purpose: Pseudohypoparathyroidism (PHP) is caused by genetic and epigenetic alteration in the GNAS locus, and characterized by the resistance to multiple hormones and the Albright's hereditary osteodystrophy (AHO) phenotype. This study investigated the phenotypic characteristics and molecular features of PHP. Methods: Eight patients who diagnosed as PHP were enrolled at Pusan National University Children's hospital and clinical features, biochemical and genetic findings were retrospectively reviewed. Results: Of a total of 8 patients, 5 were diagnosed with PHP1a, and 3 were diagnosed with PHP1b. Patients with PHP1a had three different mutations in the GNAS gene, and patients with PHPIb had imprinting defect in differentially methylated regions (DMRs) of the GNAS locus. Two novel GNAS variants were identified in patients with PHP1a, including c.313-2A>T and c.1094G>A. All patients with PHP1a displayed AHO features; short stature (80%), brachydactyly (80%), a round face (80%), obesity (40%), heterotopic ossification (60%), and intellectual disability (60%), whereas only one patient (33.3%) with PHP1b showed AHO feature such as a round face. When phenotypic features between PHP1a and PHP1b patients were compared, patients with PHP1b showed a tendency of higher current height standard deviation scores (SDS) compared to patients with PHP1a, (-3.2±2.1 vs.-1.1±0.8; P=0.06) Conclusions: This study summarizes the phenotypic and genetic features of the PHP patients. Although we found considerable clinical overlap between PHP1a and PHP1b, further long-term follow-up is needed to evaluate the growth and development of children with PHP, as well as the effects of end-organ resistances to endocrine hormones.

• KIISE Transactions on Computing Practices
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• v.21 no.11
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• pp.721-726
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• 2015

This paper shows secure coding rules for PHP programs. Programmers should comply with these rules during development of their programs. The rules are crafted to restrain 28 weaknesses that are composed of 22 corresponding to reported CVEs of PHP, the children of CWE-661 for PHP, and the top 5 weaknesses according to OWASP. The rule set consists of 28 detailed rules under 14 categories. This paper also demonstrates through examples that programs complying with these rules can curb weaknesses. The rules can also serve as a guideline in developing analysis tools for security purposes.

• Journal of Korean society of Dental Hygiene
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• v.13 no.2
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• pp.261-269
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• 2013

Objectives : This research examined the Patient Hygiene Performance(PHP) index according to smoking and tooth brushing behavior, in order to analyze how they influence the oral hygiene. Methods : This research used PHP index and the structured questionnaire. The subjects were 203 men in their 20's who visited K university's dental hygiene department for oral prophylaxis from March to July of 2012. For data analysis SPSS WIN 12.0 was used. Results : 1. The average PHP index of all experimented subjects was 2.66, a very poor level. The PHP index according to general characteristics, smoking, drinking, and exercise showed statistical significance(p<0.05). 2. PHP index decreased with more frequencies and longer durations of toothbrushing(p<0.05). 3. The PHP index of smokers is higher than that of non-smokers. In the case of non-smokers, the frequency, method, and duration of tooth brushing had a statistical significance(p<0.05). 4. The PHP index of smokers who smoke less than or equal to ten cigarettes is 2.53 and smokers who smoked more than 10 cigarettes is 3.10. 5. The results of multiple regression analysis showed that smoking increased the PHP index, while the increase in tooth brushing frequency and the up and down tooth brushing method decreased the PHP index. All the coefficients were statistically significant (p<0.05). Conclusions : In order to increase Patient Hygiene Performance(PHP) index. there must be a decrease in smoking rate while people increase their tooth brushing frequency and use a proper tooth brushing method.

• Polymer(Korea)
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• v.26 no.2
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• pp.185-192
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• 2002

Rigid polyurethane foams (PUFs) were prepared from polymeric 4.4'-diphenyl-methane diisocyanate (PMDI), polyether polyol, 1,4-butane diol, silicone surfactant, and distilled water. The density of the PUF was decreased from 173.7 to 41.7 kg/㎥ with an increase in distilled water from 0.5 to 3.0 php (parts per hundred polyol by weight), respectively, at the 0 php butane diol. The cell size of the PUF increased from 115 to 258 $mu extrm{m}$ with an increase in the amount of distilled water from 0.5 to 3.0 php, respectively, at the 10 php butane diol. It was found that the compressive strength of the PUF increased with the content of distilled water, at the same density. Out of the study for the surfactant effect on the properties of the PUF, it was observed that the cell site of the PUF decreased from 360 to 146 $mu extrm{m}$ with an increase in the amount of the surfactant from 0 to 0.33 php, respectively, but the tell size did not change significantly when the amount of the surfactant exceeded 0.33 php.

• Journal of Korean society of Dental Hygiene
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• v.15 no.3
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• pp.451-459
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• 2015

Objectives: The objective of this study is to investigate oral health behavior, PHP index and OHIP, awareness, attitude and behavior toward oral health in the foreign factory workers. Thsi study will provide the basic data for the improvement of the foreigners' quality of life. Methods: A self-reported questionnaire was completed by 126 Sri Lankans and 76 Chinese over 20 years old in Daegu and Gyeongbuk from January to April, 2012 through man to man interview after receiving informed consent. The questionnaire included oral health status, PHP index and OHIP. Results: OHIP was closely related to sex, marital status, and medical expense burden. PHP index was closely related to religion and income. The averages of OHP and PHP were 4.36 and 3.7, respectively and very bad. OHIP was influenced by number of toothbrushing, time of toothbrushing, use of oral hygiene device, and dental visit within a year. PHP index was influenced by the area of toothbrushing, time of toothbrushing, and the dental visit within a year. Regression analysis of PHP index according to OHIP and oral care conditions showed the equation. Y(OHIP)=2.999+0.103(area of toothbrushing)+0.346(the use of oral hygiene article)+ 0.077(visiting to the dentist during the past one year)-0.173(PHP index)(p<0.05). Conclusions: Low PHP index in the foreign workers affected quality of life. So the company must provide the continuing oral health care for the foreign workers every year. The concern for the health care for the foreigners will improve oral health behavior in the future.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2002.05a
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• pp.58-64
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• 2002

본 연구의 목적은 프로그램 언어(Perl/CGI, PHP)가 웹 어플리케이션의 개발성과에 미치는 영향을 조사하기 위한 것이다. 이를 위해 본 연구는 정보시스템의 복잡성과 프로그램 언어에 따른 프로그램의 생산성 효과 이론 등과 같은 선행연구(Wrigley & Dexter, 1991; McFarlan, 1981; Ha & McLean, 1985)와 연구 대상인 Perl/CGI와 PHP에 관한 이론을 조사하였다. 이를 바탕으로 프로그램 인어(Perl/CGI, PHP)가 과업의 위험성(개발사 경험, 요구사항의 난이도)에 따라 개발성과 발생산성, 개발사 만족도)에 미치는 영향을 조사하기 위한 모델을 개발하고 실험을 통해 이를 검증하였으며, 결과는 다음과 같다. 사용 언어에 따른 집단별(초보자집단/전문가집단) 성과의 차이는 요구사항이 간단할 경우에는 초보자집단과 전문가집단 사이에 개발성과의 차이점을 발견할 수 없었다. 그러나 요구사항이 복잡할 경우에는 두 개의 프로그램 언어 모두에 대해 전문가 집단이 초보자 집단보다 개발성과가 높게 나타났다. 또한 사용 언어별 성과에서는 PHP를 사용하는 경우가 Perl/CGI를 사용하는 경우보다 개발자 경험이나 요구사항의 난이도와 관계없이 높은 개발성과를 보여 주었다.

• Journal of applied mathematics & informatics
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• v.37 no.1_2
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• pp.157-162
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• 2019

Programming tools are essential for students learning numerical analysis. It is troublesome to go to a laboratory where a computer is located after taking a lecture. Nowadays most students have mobile phones which can be used for programming practice through the Internet. PHP is a server-side scripting language designed for web development but also used as a general-purpose programming language. However, PHP has many inconveniences, such as adding a dollar symbol ($) to every varable. This paper introduces a slightly modified language, NAPHP, and a system which is designed for students to use their own mobile phone to write down the language NAPHP and run it on the web page. The system NAPHP-SYS is an educational tool that turns NAPHP into PHP, run PHP code and show the results on the web.

• The KIPS Transactions:PartA
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• v.18A no.5
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• pp.193-204
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• 2011

Since web applications are accessed by anonymous users via web, more security risks are imposed on those applications. In particular, because security vulnerabilities caused by insecure source codes cannot be properly handled by the system-level security system such as the intrusion detection system, it is necessary to eliminate such problems in advance. In this paper, to enhance the security of web applications, we develop a static analyzer for detecting the well-known security vulnerability of PHP file inclusion vulnerability. Using a semantic based static analysis, our vulnerability analyzer guarantees the soundness of the vulnerability detection and imposes no runtime overhead, differently from the other approaches such as the penetration test method and the application firewall method. For this end, our analyzer adopts abstract interpretation framework and uses an abstract analysis domain designed for the detection of the target vulnerability in PHP programs. Thus, our analyzer can efficiently analyze complicated data-flow relations in PHP programs caused by extensive usage of string data. The analysis results can be browsed using a JAVA GUI tool and the memory states and variable values at vulnerable program points can also be checked. To show the correctness and practicability of our analyzer, we analyzed the source codes of open PHP applications using the analyzer. Our experimental results show that our analyzer has practical performance in analysis capability and execution time.

• Journal of the Korean Data and Information Science Society
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• v.10 no.2
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• pp.501-510
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• 1999

We have seen a rapid development of multimedia intustry as computer evolves and the internet has changed our way of life dramatically in these days. There we several attempts to teach elementary statistics on the web but most of them are based on commercial products. The need for statistical data analysis and decision making based on those analysis is growing. In this article we try to show one way of reaching that goal by using a server side scripting language PHP3 toghether with extra graphical module and statistical distribution module on the web. We showed some elementary exploratory graphical data analysis and statistical inferences. There are plenty of room of improvements to make it a full blown statistical analysis tool on the web in the new future. All the programs and databases used in our article we public programs. The main engine PHP3 is included as an apache web server module so it is very light and fast. It will be much better when the PHP4(ZEND) will be officially out in terms of processing speed.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.20 no.2
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• pp.44-49
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• 2020

Pseudohypoparathyroidism (PHP) is a disorder characterized by hypocalcemia and hyperphosphatemia due to end organ resistance to parathyroid hormone. PHP is caused by the deficiency of the α-subunit of the stimulatory G protein encoded by the GNAS gene, and this defect arises from genetic or imprinting disturbances. Sporadic PHP 1b shows two or more methylation defects of upstream of GNAS gene and some of them lead to loss of maternal GNAS imprints, therefore, only paternally derived GNAS gene is expressed. Here, we report a 10 year 9 month old boy presented with intermittent tetany who was finally diagnosed with PHP 1b caused by paternal uniparental disomy of chromosome 20q.