• Title/Summary/Keyword: PIH

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Different Levels of Platelet Activation in Normal Pregnancy and Pregnancy-induced Hypertension (PIH)

  • Jo, Yoon-Kyung;Im, Jee-Aee;Eom, Yong-Bin;Suh, Sang-Hoon
    • Biomedical Science Letters
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    • v.13 no.1
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    • pp.11-15
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    • 2007
  • We examined the effects of pregnancy and pregnancy-induced hypertension (PIH) on platelet activation. Thirty-six women with PIH (blood pressure > 140/90 mm Hg after two consecutive measurements after the $24^{th}$ weeks of gestation) without proteinuria, fifty-six normotensive pregnant women, and fifty non-pregnant women were studied. WBC, RBC, platelet related variables, including mean platelet component (MPC), mean platelet volume (MPV) and platelet component distribution width (PCDW) were determined for this study. MPC levels were significantly lower in women with PIH compared with normotensive pregnant women and non-pregnant women (P<0.05). MPC levels were inversely con-elated with PIH (r=-0.49, P<0.001), systolic BP (r=-0.22, P<0.01), diastolic BP (r=-0.17, P<0.005), WBC (r=-0.30, P<0.001), MPV (r=-0.41, P<0.001), and PCDW (r=-0.68, P<0.001), and positively con-elated with RBC (r=0.32, P<0.001), platelet count (r=0.21, P<0.05), and mean platelet mass (MPM) (r=0.18, P<0.05). MPC levels were found to be an independent factor associated with PIH and PCDW (P<0.01) after adjustments were made for potential confounding factors such as gestational age, systolic blood pressure, diastolic blood pressure, WBC, RBC, Platelet count, and PCDW. In conclusion, MPC levels were significantly lower in women with PIH, and MPC levels were found to be an independent factor associated with PIH and PCDW. Therefore, platelet activation is suggested as a useful predictor for patients with PIH.

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Development of Discriminant Model of PIH Pregnant using Decision Tree

  • Park, Young-Sun;Choi, Hang-Suk;Cha, Kyung-Joon;Park, Moon-Il
    • Journal of the Korean Data and Information Science Society
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    • v.16 no.1
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    • pp.41-50
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    • 2005
  • The various methods have been studied to develop discriminant model for pregnancy induced hypertension(PIH) as high risk pregnant. In this study, we adapt the approximate entropy which is the non-linear chaotic measuring method. Then, we develop a system to discriminant PIH pregnant using QUEST with S-PLUS.

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Validity and Reliability of the Korean Version of the Partners In Health Scale (PIH-K) (한국어판 자기관리 측정도구(Partners In Health scale)의 타당도 및 신뢰도 분석)

  • Jeon, Mi-Kyeong;Ahn, Jung-Won;Park, Yeon-Hwan;Lee, Mi-Kyoung
    • Journal of Korean Critical Care Nursing
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    • v.12 no.2
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    • pp.1-12
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    • 2019
  • Purpose : The purpose of this study was to validate the Korean version of Partners In Health scale (PIH-K) which is used to measure the self-management of patients with chronic illnesses in Korea. Methods : Translation of the 12-item PIH-K was conducted according to the World Health Organization guidelines. Data from 306 participants who took medicines over 3 months by doctor's prescription were collected from October to November 2017. Validity such as content validity, construct validity, and concurrent validity were conducted using content validity index (CVI), exploratory and confirmatory factor analyses (CFA). To evaluate concurrent validity, the correlation coefficients between the PIH-K and concurrent scales (Self-As-Carer Inventory) were calculated. The reliability of the PIH-K was examined using the internal consistency and test-retest reliability tests. Results : The CVI of the PIH-K was 0.91. According to the CFA, factor loadings for four factors ranged from .64 to .97, which explained 67.5% of the total variance. The PIH-K was significantly correlated with concurrent variables such as those on the Self-As-Carer Inventory. The Cronbach's ${\alpha}$ was .86 and the intraclass correlation coefficient for the two-week test-retest reliability was .88. Conclusion : Findings show that the PIH-K is reliable and valid in measuring self-management of patients with chronic illnesses.

Postinflammatory Hyperpigmentation Secondary to Acupuncture and Cupping Successfully treated with 1,064-nm Picosecond-Domain Neodymium:Yttrium-Aluminum-Garnet Laser

  • Lee, Hae-Jin;Lee, Seung Hun;Yoon, So Young;Kim, Youn Jin;Kim, Young Koo
    • Medical Lasers
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    • v.8 no.1
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    • pp.32-34
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    • 2019
  • Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis of the skin that occurs as a result of variable inflammatory processes, such as trauma, and many inflammatory conditions. Although a range of modalities of managing PIH have been reported, the treatment of PIH is challenging. In this report, a patient with PIH was treated using picosecond-domain Nd:YAG lasers. After three sessions of 1,064-nm picosecond-domain Nd:YAG laser treatment, the patient showed almost complete improvement with no remarkable side effects or recurrence over the duration of six months. Overall, 1,064-nm picosecond-domain Nd:YAG laser can be used effectively and safely for treating pigmented lesions in the dermis, particularly PIH, in Asian patients.

Hematologic Status of Newborn Infants of Mother with Pregancy-induced Hypertension (임신성 고혈압 산모의 태아의 혈액상)

  • Lee, Doo-Jin;Koh, Min-Whan;Lee, Sung-Ho
    • Journal of Yeungnam Medical Science
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    • v.11 no.2
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    • pp.352-362
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    • 1994
  • To evaluate the effects of pregnancy-induced hypertension (PIH) to the iron status of fetuses, umbilical cord blood of 35 newborn infants borne by PIH mothers and of 37 normal term infants delivered at Yeungnam University Hospital from September 1, 1993 to September 30, 1994, were studied. The serum hemoglobin concentration of women with PIH was significantly higher than normal full-term pregnant women. There was no significant difference in serum hemoglobin concetration between women with PIH and normal full-term pregnant women and their newborn infants. There was no significant difference in serum hemoglobin concentration beween infants of women with PIH and normal full-term infants. The serum iron concentration of newborn infants of women with PIH was higher and the serum ferritin concentration of newborn infants of women with PIH was lower than normal full-term infants, but there were no significant difference between the two groups. The serum total iron-binding capactity and unsaturated iron-binding capacity of infants of women with PIH were significantly higher than normal full-term infants. The newborn infants of PIH women seemed that they might have occult depletion of iron store and need meticulous follow up during early neonatal period.

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Development of Discriminant Model of PIH Pregnant using Decision Tree

  • Park, Young-Sun;Choi, Hang-Suk;Lee, Young-Koun;Cha, Kyung-Joon;Lee, Sung-Hoon;Park, Moon-Il
    • 한국데이터정보과학회:학술대회논문집
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    • 2004.04a
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    • pp.141-149
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    • 2004
  • The various methods have been studied to develop discriminant model for Pregnancy Induced Hypertension(PIH) as high risk pregnant. In this study, we adapt the approximate entropy which is the non-linear chaotic measuring method. Then, we develop the system to discriminant PIH pregnant using QUEST with S-PLUS.

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Postinflammatory Hyperpigmentation Secondary to Liposuction Successfully Treated with a 1,064-nm Picosecond-Domain Neodymium:Yttrium-Aluminum-Garnet Laser

  • Lee, Hae-Jin;Kim, Young Koo
    • Medical Lasers
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    • v.8 no.2
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    • pp.87-89
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    • 2019
  • Post inflammatory hyperpigmentation (PIH) is a reactive hypermelanosis of the skin that occurs as a result of various inflammatory responses such as surgical procedure, trauma, and many inflammatory conditions. There are several reported studies of various modality in managing PIH. However, the treatment of PIH can prove to be challenging. In this report, we treated a patient with PIH using picosecond-domain Nd:YAG lasers. After ten sessions of 1,064-nm picosecond-domain Nd:YAG laser treatment, the patient presented considerable improvement with no remarkable side effects or recurrence over the duration of 6 months. We suggest that a 1,064-nm picosecond-domain Nd:YAG laser can be effectively and safely used for treating pigmented lesions resulting from surgical procedure in the skin of Asian patients.

Effect of early postnatal neutropenia in very low birth weight infants born to mothers with pregnancy-induced hypertension

  • Park, Yang Hee;Lee, Gyung Min;Yoon, Jung Min;Cheon, Enn Jung;Ko, Kyung Ok;Lee, Yung Hyuk;Lim, Jae Woo
    • Clinical and Experimental Pediatrics
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    • v.55 no.12
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    • pp.462-469
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    • 2012
  • Purpose: In this study, we aimed to investigate the perinatal clinical conditions of very low birth weight (VLBW) infants born to mothers with pregnancy-induced hypertension (PIH) focusing on the effects of early postnatal neutropenia. Methods: We reviewed the medical records of 191 VLBW infants who were born at Konyang University Hospital, between March 2003 and May 2011. We retrospectively analyzed the clinical characteristics of the infants and their mothers and compared the incidence of perinatal diseases and mortality of the infants according to the presence or absence of maternal PIH and neutropenia on the first postnatal day. Results: Infants born to mothers with PIH showed an increased incidence of neutropenia on the first postnatal day (47.4%), cesarean delivery, and intrauterine growth restriction. When the infants born to mothers with PIH showed neutropenia on the first postnatal day, their incidence of respiratory distress syndrome (RDS) was increased (P=0.031); however, the difference was not found to be significant through logistic regression analysis. In all the VLBW infants, neutropenia on the first postnatal day was correlated with the development of RDS. The incidence of the other perinatal diseases involving sepsis and mortality did not significantly differ according to the presence or absence of neutropenia in infants born to mothers with PIH. Conclusion: In VLBW infants born to mothers with PIH, the incidence of neutropenia on the first postnatal day was increased and it was not significantly correlated with the development of perinatal diseases involving RDS, sepsis, and mortality.

Comparison of Mineral Contents in Colostrum of the Mothers with Fullterm, Preterm Delivery and Pregnancy Induced Hypertension (만기분만과 조산 및 임신성 고혈압 산모의 초유내 무기질 함량 비교)

  • 안홍석;이주예
    • Journal of Nutrition and Health
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    • v.34 no.6
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    • pp.656-663
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    • 2001
  • This study was carried out to evaluate the minerals and trace elements contents in colostrum milk produced from 30 normal healthy mothers delivery at term, 10 mothers delivery preterm and 8 pregnancy induced hypertensive mothers(PIH) and to investigate the relationship between maternal minerals intakes during pregnancy and milk contents of minerals. Five minerals(Na, K, Ca, P, Mg) and three trace elements(Fe, Zn, Cu) in colostrum were determined by ICP-AES and maternal dietary intakes during pregnancy were estimated by semiquantitative frequency questionnaire. Maternal dietary intakes of three groups during pregnancy were below the recommended allowances except protein and phosphorus. The overall mean nutrients intakes of mothers delivered preterm were the lowest among three study groups, especially phosphorus and sodium intakes of preterm mothers were significantly lower than those of normal term mothers(p < 0.05). Dietary intakes of mothers with pregnancy induced hypertension were similar to those of normal term mothers except calcium intake of pregnancy induced hypefensive mother was the lowest among three groups. While potassium and phosphorus concentrations in preterm colosalm were significantly lower than those of term milk(p < 0.05), iron contents of colostrum in preterm and PIH groups were significantly higher than term milk respectively(p < 0.07). The other minerals concentrations of colostrum produced by the preterm mothers tended to be lower than term milk. There were not significant relationships between maternal dietary intakes of minerals during pregnancy and the corresponding mineral levels of colostrum of three groups of mothers except that Pearson correlation coefficient showed positive significant relationships between the calcium intakes of PIH mothers and the colostrum milk calcium levels. These results suggest that preterm milk might be insufficient for the mineral nutrition of preterm infects in considering of the poor tissue storage of minerals and catch-up growth of preterm infects.

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Maximum-Likelihood Estimation using a Variance-Covariance Relationship of Stochastic elements within a panel (패널내 추계적 요인들의 공분산 관계에 의한 최우추정)

  • 이회경;이진우
    • Korean Management Science Review
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    • v.11 no.2
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    • pp.29-41
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    • 1994
  • This paper analyses the stochastic nature of the Permanent Income Hypothesis (PIH) by specifying the variance-covariance structure of PIH based on Hall and Mishkin[3]. Maximum likelihood is employed to estimate the model by explicitely incorporating the heteroscedastic nature of the data into the likelihood. The data used are individual Korean household consumption and income data. The results indicate that the data are generally consistent with the Permanent Income Hypothesis, and about 11 percent of the total variation in consumption may be attributable to the excess sensitivity of consumption to income.

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