• Journal of electromagnetic engineering and science
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• v.13 no.3
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• pp.186-188
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• 2013

A triple 2-of-3 pulse repetition frequency (PRF) scheme is presented for medium PRF pulsed-Doppler airborne radars, and a real-time method is developed that searches for optimal or sub-optimal PRF sets according to momentary battle situations. The effectiveness of the real-time search method of PRF sets is demonstrated by the experimental results obtained using simulated data.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.30 no.6
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• pp.498-506
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• 2019

In this paper, we propose a PRF design method to improve the performance of the ESA radar, by excluding the interference from an improper PRF. Like the conventional method, the proposed method also considers the interference between the transmitted signal and the nadir signal, but additionally analyzes the relationship between the interference and the signal beamwidth. The simulation results show that the proposed method quantitatively and qualitatively excluded interference from the PRF and additionally dealt with the beamwidth broadening effect of an ESA radar.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.965-966
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• 2014

The range and velocity ambiguities depending on the selected PRF are the serious problems in ultrasonic measurement. Therefore, the PRF selection method in the generation of waveform are analyzed. Also, the effects on measurements are discussed.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.27 no.6
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• pp.521-530
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• 2016

Weather radar is observation equipment that transmits electromagnetic waves and receives backscattered signals from the targets. The weather radar systems of the Korea Meteorological Administration have a doppler mode that can extract the target's radial velocity. However, the radial velocity over the maximum unambiguous velocity(${\nu}_m$) for which is in a trade-off relationship with the maximum unambiguous range is folded. Therefore, a dual PRF mode of which transmits and receives signals using two different PRFs(high and low) must be used to extend the vm while maintaining the maximum unambiguous range. Using a dual PRF mode, vm can be extended to the amount of lowest common denominator of two observed vm from high and low PRF. For this extension, we have developed a velocity unfolding algorithm of which uses several criteria for classification considering observed velocity differences between high and low PRF and their error boundary. Then, correction factors are calculated for each class and are applied to unfold radial velocity. The developed algorithm was applied to the Yong-In Testbed(YIT) radar and the generated better performance of radial velocity extraction than those of the previous system.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.48 no.6
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• pp.371-381
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• 2022

Objectives: This study determined the effect of platelet-rich fibrin (PRF) on extraction socket bone regeneration and assessed the patterns and determinants of bone regeneration after the surgical extraction of impacted mandibular third molars. Materials and Methods: This prospective study randomly allocated 90 patients into two treatment groups: A PRF group (intervention group) and a non-PRF group (control group). After surgical extractions, the PRF group had PRF placed in the extraction socket and the socket was sutured, while the socket was only sutured in the non-PRF group. At postoperative weeks 1, 4, 8, and 12, periapical radiographs were obtained and HLImage software was used to determine the region of newly formed bone (RNFB) and the pattern of bone formation. The determinants of bone regeneration were assessed. Statistical significance was set at P<0.05. Results: The percentage RNFB (RNFB%) was not significantly higher in the PRF group when compared with the non-PRF group at postoperative weeks 1, 4, 8, and 12 (P=0.188, 0.155, 0.132, and 0.219, respectively). Within the non-PRF group, the middle third consistently exhibited the highest bone formation while the least amount of bone formation was consistently observed in the cervical third. In the PRF group, the middle third had the highest bone formation, while bone formation at the apical third was smaller compared to the cervical third at the 8th week with this difference widening at the 12th week. The sex of the patient, type of impaction, and duration of surgery was significantly associated with percentage bone formation (P=0.041, 0.043, and 0.018, respectively). Conclusion: Placement of PRF in extraction sockets increased socket bone regeneration. However, this finding was not statistically significant. The patient's sex, type of impaction, and duration of surgery significantly influenced the percentage of bone formation.

• YAKHAK HOEJI
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• v.50 no.1
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• pp.8-14
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• 2006

A 1 : 1 mixture of acriflavine (ACF; CAS 8063-24-9) and guanosine is currently being evaluated as a possible antitumor agent in preclinical studies. Guanosine is known to potentiate the anticancer activity of some compounds. However, the distributions of trypaflavine (TRF) or proflavine (PRF) have not been investigated in mammals. We, therefore, investigated the distribution of TRF and PRF after i.m. administration of the combination mixture (ACF and guanosine) at a dose of 30 mg/kg ACF in rats. to analyze TRF and PRF levels in biological samples, we used an HPLC-based method. The calibration curves for TRF and PRF in the samples were linear over the concenration range of $0.05{\sim}200\;{\mu}g/ml$. The intra- and inter-day assay accuracies of this method were within ${\pm}15\%$ of norminal values and the precision did not exceed $15\%$ of relative standard diviation. The lower limits of quantitation were 50 ng/ml for both TRF and PRF. The distribution of TRF or PRF was determined by 48 h after i.m. administration of the combination mixture at a dose of 30 mg/kg ACF. TRF and PRF were distributed as the following order; kidney>lung>liver>small intestine>muscle. Of the various tissues, TRF and PRF were mainly distributed to the kidney and lung. The concentrations of TRF or PRF in the tissues 24 h after i.m. administration decreased to undetectable levels. The concentrations of TRF or PRF in the blood cells were comparable to those for the plasma. However, the concentrations of TRF or PRF in the both plasma and blood cells 12 h after i.m. administration were not detected. The number of the platelets in the 1 ml of the blood was calculated to be $0.183{\times}10^8/ml$ of blood. The PRF concentration in platelets was higher than that of TRF at initial times after i.m. administration of the combination mixture. However, both the TRF and PRF concentrations in the plateles 24 h after i.m. administration of the combination mixture were below the quantifiable limit. In conclusion, the concentrations of TRF or PRF in the various tissues, plasma, blood cells, and plateles decreased to undetectable levels 24 h after i.m. administration of the combination mixture at a dose of 30 mg/kg ACF.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.34 no.2
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• pp.155-161
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• 2012

Platelet-rich fibrin (PRF) is a strong but flexible fibrin including a enrich platelet which contain growth factors and cytokines. PRF can be made very simply and requires no artificial additives unlike platelet-rich plasma. While PRF is remodeled and released in the tissue, this induces cell growth, vascularization, collagen synthesis, osteoblast differentiation and an anti-inflammatory reaction. Taking advantage of these functions, PRF can stimulate regeneration of bone and soft tissue in a diverse number of ways during the course of hemostasis, wound coverage, preservation, and reconstruction of alveolar bone. Moreover, the use of PRF to improve bone regeneration has become a recent technique in implantology. In this study, through a literature review of PRF's existing clinical applications, we classified a range of potential PRF oral and maxillofacial surgery applications including preservation of extraction sockets, guided bone graft, sinus lift, dressing and periodontal treatment. This trial gave us chance to confirm the usefulness of PRF. Recently, updated clinical studies results concerning skin and tendon wound healing have become available. These results suggest that the usage of RPF will gradually expand.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.10
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• pp.1050-1061
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• 2014

Airborne radar usually use MPRF(medium PRF) waveforms to detect and track look-down or all-directions air-to-air targets. To use MPRF waveforms, airborne radar have to operate optimal PRF schedules and select optimal PRFs able to detect look-down air-to-air targets, overcoming look-down clutter and resolving range/velocity ambiguities. In this paper, we propose a real-time search method for the optimal(and sub-optimal) PRFs able to detect and track targets in real-time change of situation for MPRF pulsed-Doppler airborne radars.

• Journal of the Korea Institute of Military Science and Technology
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• v.24 no.4
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• pp.368-373
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• 2021

This paper presents a method of independent pulse repetition frequency(PRF) generation and control for frequency phase calibration on mono-pulse radar at a remote location. In order to generate an independent PRF signal of 320[Hz], pulse width modulation(PWM) of 16-bit timer/counter was applied. For a precision control of PRF signal, 16-bit timer/counter interrupt was changed for each period. Therefore, average frequency of PRF could be controlled by 0.0001[Hz]. To calibrate a frequency phase of mono-pulse radar at a remote location, the proposed PRF generator with a precision control of frequency was used regardless of receiving PRF signal from a radar. For the verification of the proposed PRF generator, theoretical analysis and experimental results are included.

• Journal of Life Science
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• v.32 no.7
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• pp.542-549
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• 2022

Polymethoxyflavones (PMFs) are flavonoids mainly found in citrus fruits and have been reported to exhibit a wide range of bioactivities, including anti-obesity, anti-cancer, and anti-inflammatory actions. To utilize PMFs as functional materials, it is necessary to develop a simple method of obtaining PMFs from citrus tissues containing a large amount of PMFs. It has been reported that Jinkyool (C. sunki Hort ex. Tanaka) peel contained a large amount of PMFs, but there are no studies on PMFs isolated from its leaves. In this study, we established a simple procedure for obtaining the PMF-rich fraction (PRF) from the leaves of Jinkyool and investigated the effects of PRF on lipid metabolism in 3T3-L1 cells. PRF inhibited lipogenesis during the differentiation of 3T3-L1 preadipocytes. It decreased the expression of peroxisome proliferator-activated receptor gamma (PPAR𝛾) and CCAAT/enhancer binding protein alpha (CEBP𝛼), FAS, and adipocyte fatty-acid-binding protein 2 (aP2). In mature 3T3-L1 adipocytes, PRF increases the phosphorylation of protein kinase A (PKA)/hormone-sensitive lipase (HSL), which are key factors involved in lipolysis. Moreover, it increases the phosphorylation of the AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) involved in fatty acid oxidation. These results suggest that PRF from Jinkyool leaves can be used as an anti-obesity agent with the action of inhibiting lipogenesis and promoting lipolysis and fatty acid oxidation in 3T3-L1 adipocytes.