• Title/Summary/Keyword: Palate

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Phonological Characteristics of Early Vocabulary in Young Children with Cleft Palate (구개열 아동의 초기 어휘에 나타난 음운 특성 연구)

  • Ha, Seunghee
    • Phonetics and Speech Sciences
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    • v.6 no.2
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    • pp.65-71
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    • 2014
  • The purpose of this study was to investigate whether young children with cleft palate differ from those of noncleft typically developing children in terms of expressive vocabulary size, phonological characteristics and lexical selectivity. A total of 12 children with cleft palate and 12 noncleft children who were matched by age and gender participated in the study. The groups were compared by size of expressive vocabulary reported on Korean version of MacArthur-Bates Communicative Development Inventories and the number of different words, consonant inventory, the percentage of words beginning with obstruents and vowels, nasal, and glottal sounds, and the percentage of words which do not include obstruents in a language sample. Also, correlation analysis were performed to examine the relationship between measures on size of expressive vocabulary and phonological characteristics. The results showed that expressive vocabulary size and consonant inventory for children with cleft palate produced significantly smaller than those for noncleft children. Children with cleft palate produced significantly more words beginning with vowel or which do not include obstruents, and fewer words beginning with obstruents than noncleft children. The two groups showed different results on significant correlations between measures on size of expressive vocabulary and phonological characteristics indicating that children with cleft palate show different lexical selectivity from their noncleft peers. The results suggest that children with cleft palate aged 18-30 months demonstrate a slower rate of lexical and phonological development compared with their noncleft peers and they develop lexical selectivity reflecting cleft palate speech. The results will have a clinical implication on speech-language intervention for young children with cleft palates.

IMMUNOHISTOCHEMICAL DETECTION OF GROWTH FACTORS AND EXTRACELLULAR MATRIX PROTEINS IN THE DEGENERATING TISSUES OF PRE-AND POSTNATAL HUMAN CLEFT LIP AND PALATE (태생 및 생후 구순.구개열에 나타나는 조직변성에 대한 성장인자와 세포외 기질 단백의 면역조직화학적 연구)

  • Min, Bong-Gi;Lee, Suk-Keun;Park, Young-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.6
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    • pp.421-433
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    • 2002
  • In order to elucidate the pathogenesis of cleft lip and palate, first of all, it is necessary to understand the developmental mechanisms of growth factors and extracellular matrix proteins in the tissues of cleft lip and palate. We have performed immunohistochemical studies on human cleft lip and palate tissues to elucidate the pathogenetic implications of cleft lip and palate. 16 specimens from postnatal human cleft lip and palate subjects and 17 specimens from autopsy of prenatal human cleft lip and palate were fixed in 10% buffered formalin, embedded in paraffin. The sections were routinely stained by hematoxylin and eosin, also stained by PAS, and followed by immunohistochemical stainings using the antiseras of growth factors and extracellular matrix proteins such as PCNA, S-100, c-erb-B2, MMP-3, MMP-10, HSP-70, transglutaninase-C, E-cadherin, VEGF, vWF. Both the prenatal and postnatal specimens of cleft lip and palate showed dysplastic proliferation of the basal cell layer, increased infiltration of melanocytes into mucosal epithelium, sebaceous gland hyperplasia ingrowing into the muscular tissue of lip and palate, and fatty infiltration into the submucosal deep connective tissue. The strong reactions of MMP-3 and HSP-70 were detected in the tissues of cleft lip and palate, especially increased in degenerating muscle bundles, while the immunostainings of PCNA and c-erb-B2 were weakly positive in the tissues of cleft lip and palate. These data suggest that the retrogressive tissue degeneration around the cleft areas persistently exist during the prenatal and postnatal period after cleft formation, and the sebaceous gland hyperplasia and fatty infiltration with the intense expression of MMP-3 and HSP-70 is closely related to the muscular degeneration around the cleft area.

CHARACTERISTICS OF OROPHARYNGEAL AIR PRESSURE, AIRFLOW IN CLEFT PALATE PATIENTS (구개열 환자에서의 구강인두압력 및 공기유량에 관한 음성학적 특징)

  • Baek, Jin-A
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.1
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    • pp.13-20
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    • 2006
  • The articulation disorders associated with velopharyngeal insufficiency (VPI) in cleft palate patients are interested to clinicians particularly. The purpose of this study was to investigate mainly the oropharyngeal air pressure and overall air flow in cleft palate patients. The pressure-measuring catheter was positioned at the midportion of the oropharyngeal cavity with a facial mask. Test words were composed of 9 meaningless polysyllabic words and 17 meaningful words. Aerophone II and Nasometer II were used to measure peak air pressure, mean air pressure, maximum flow rate, volume, phonatory flow rate, nasalance. The data shows that airflow of the cleft palate patient group were higher than those of the control group. Intraoral air pressure of the cleft palate patient group was lower than those of the control group. The first vowel formant and first Bandwidths of the cleft palate patient group were higher than those of the control group.