• Title/Summary/Keyword: Pattern consistency index

Search Result 24, Processing Time 0.029 seconds

Missing values imputation for time course gene expression data using the pattern consistency index adaptive nearest neighbors (시간경로 유전자 발현자료에서 패턴일치지수와 적응 최근접 이웃을 활용한 결측값 대치법)

  • Shin, Heyseo;Kim, Dongjae
    • The Korean Journal of Applied Statistics
    • /
    • v.33 no.3
    • /
    • pp.269-280
    • /
    • 2020
  • Time course gene expression data is a large amount of data observed over time in microarray experiments. This data can also simultaneously identify the level of gene expression. However, the experiment process is complex, resulting in frequent missing values due to various causes. In this paper, we propose a pattern consistency index adaptive nearest neighbors as a method of missing value imputation. This method combines the adaptive nearest neighbors (ANN) method that reflects local characteristics and the pattern consistency index that considers consistent degree for gene expression between observations over time points. We conducted a Monte Carlo simulation study to evaluate the usefulness of proposed the pattern consistency index adaptive nearest neighbors (PANN) method for two yeast time course data.

A Pattern Consistency Index for Detecting Heterogeneous Time Series in Clustering Time Course Gene Expression Data (시간경로 유전자 발현자료의 군집분석에서 이질적인 시계열의 탐지를 위한 패턴일치지수)

  • Son, Young-Sook;Baek, Jang-Sun
    • The Korean Journal of Applied Statistics
    • /
    • v.18 no.2
    • /
    • pp.371-379
    • /
    • 2005
  • In this paper, we propose a pattern consistency index for detecting heterogeneous time series that deviate from the representative pattern of each cluster in clustering time course gene expression data using the Pearson correlation coefficient. We examine its usefulness by applying this index to serum time course gene expression data from microarrays.

Stability of High Internal Phase Emulsions

  • Park, C.I.;Cho, W.G.
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.25 no.4 s.34
    • /
    • pp.65-74
    • /
    • 1999
  • We have studied the stability of W/O high internal phase emulsions(HIPE) containing water, cetyl dimethicone copolyol and oils varying magnesium sulfate in the range 0 to 0.5 wt% and oil polarities, respectively. The rheological consistency was mainly destroyed by the coalescence of the deformed water droplets. The greater the increase of complex modulus was, the less coalescence occurred and the more consistent the concentrated emulsions were. The increasing pattern of complex modulus versus volume fraction has been explained with the resistance to coalescence of the deformed interfacial film of water droplets in concentrated W/O emulsion. The stability is dependent on: (i) the choice of the oil is important, the requirements coincide with the requirements for the formation of the rigid liquid crystalline phases; and (ii) addition of salts the aqueous phase opposes the instability due to coalescence. Increasing the salt concentration increases the refractive index of the aqueous phase. It lowers the difference in the refractive index between the oil and aqueous phases. This decreases the attraction between the water domains, thus increasing the stability.

  • PDF

Stability of High Internal Phase Emulsions

  • Park, C-I.;W-G. Cho
    • Proceedings of the SCSK Conference
    • /
    • 1999.10a
    • /
    • pp.65-74
    • /
    • 1999
  • We have studied the stability of W/O high internal phase emulsions(HIPE) containing water, cetyl dimethicone copolyol and oils varying magnesium sulfate in the range 0 to 0.5wt% and oil polarities, respectively. The rheological consistency was mainly destroyed by the coalescence of the deformed water droplets. The greater the increase of concentrated modulus was, the less coalescence occurred and the more consistent the concentrated emulsions were. The increasing pattern of complex modulus versus volume fraction has been explained with the resistance to coalescence of the deformed interfacial film of water droplets in concentrated W/O emulsion. The stability is dependent on: (i) the choice of the oil is important, the requirements coincide with the requirements for the formation of the rigid liquid crystalline phases :5; and (ii) addition of salts the aqueous phase opposes the instability due to coalescence:. Increasing the salt concentration increases the refractive index of the aqueous phase. It lowers the difference in the refractive index between the oil and aqueous phases. This decreases the attraction between the water domains, thus increasing the stability.

  • PDF

Development of Drought Index based on Streamflow for Monitoring Hydrological Drought (수문학적 가뭄감시를 위한 하천유량 기반 가뭄지수 개발)

  • Yoo, Jiyoung;Kim, Tae-Woong;Kim, Jeong-Yup;Moon, Jang-Won
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.37 no.4
    • /
    • pp.669-680
    • /
    • 2017
  • This study evaluated the consistency of the standard flow to forecast low-flow based on various drought indices. The data used in this study were streamflow data at the Gurye2 station located in the Seomjin River and the Angang station located in the Hyeongsan River, as well as rainfall data of nearby weather stations (Namwon and Pohang). Using streamflow data, the streamflow accumulation drought index (SADI) was developed in this study to represent the hydrological drought condition. For SADI calculations, the threshold of drought was determined by a Change-Point analysis of the flow pattern and a reduction factor was estimated based on the kernel density function. Standardized runoff index (SRI) and standardized precipitation index (SPI) were also calculated to compared with the SADI. SRI and SPI were calculated for the 30-, 90-, 180-, and 270-day period and then an ROC curve analysis was performed to determine the appropriate time-period which has the highest consistency with the standard flow. The result of ROC curve analysis indicated that for the Seomjin River-Gurye2 station SADI_C3, SRI30, SADI_C1, SADI_C2, and SPI90 were confirmed in oder of having high consistency with standard flow under the attention stage and for the Hyeongsan River-Angang station, SADI_C3, SADI_C1, SPI270, SRI30, and SADI_C2 have order of high consistency with standard flow under the attention stage.

The Development of Obese Pattern Identification Questionnaire for Uzbekistan (우즈베키스탄 비만변증 설문지 개발)

  • Kim, Yunyoung;Moon, Jin Seok;Choi, Sun Mi;Jang, Eunsu
    • Journal of Korean Medicine for Obesity Research
    • /
    • v.16 no.1
    • /
    • pp.1-10
    • /
    • 2016
  • Objectives: The purpose of this study was to develop Russian version of Korean obese pattern identification questionnaire (KOPIQ) and classify the pattern of Uzbekistan obese patients. Methods: This study was conducted from 10 September 2014 to 10 December 2014 in Korea-Uzbekistan Oriental Hospital. The KOPIQ was translated to Russian language with the help of local expert in Russia and Korean Medicine. The patients who visited obese clinic in hospital were guided to join this study and informed consent was obtained. The inclusion criteria was >$23kg/m^2$ in body mass index. The Cronbach's alpha was used for it's inter consistency reliability and the KOPIQ result was compared with the experts one. Results: The Russian version of KOPIQ was developed. The 103 patient (25 males, 78 females; average age 57.2 years) joined in this study. The Cronbach's alpha of questionnaire was 0.787~0.883 according to individual pattern. The agreement rate of pattern Identification between local expert and KOPIQ was 13%. This developed questionnaire was realized as web version, which could be easily used in Uzbekistan. Conclusions: The Russian version of KOPIQ is developed in this study with suitable reliability. Further study is needed for KOPIQ to be applied in Uzbekistan with high validity.

Risk Analysis Based on Accident-Category for Railway Work Zones (철도건설현장의 사고유형기반 위험도 분석)

  • Park, Mi-Yun;Choi, Eun-Soo;Park, Joo-Nam;Choi, Seung-Sun
    • Journal of the Korean Society for Railway
    • /
    • v.12 no.2
    • /
    • pp.260-266
    • /
    • 2009
  • The theory of risk is applied frequently in analysis of railway accidents. The aim of risk analysis is to search potential causes and contribution factors of accidents by checking the total system of construction field. This paper analyze a pattern and a cause of accident occupied in construction field, calculate risk index considering accident frequency and severity, and then provide the relative risk assessment. Based on this, this paper will provide the methodology of qualitative risk assessment guiding to reach a consistency of risk index with risk assessment.

The Characteristics and Predictability of Convective System Based on GOES-9 Observations during the Summer of 2004 over East Asia (정지기상위성의 밝기온도로 분석한 2004년 동아시아지역에서 발생한 여름철 대류 시스템의 특성과 그 예측 가능성)

  • Baek, Seon-Kyun;Choi, Young-Jean;Chung, Chu-Yong;Cho, Chun-Ho
    • Atmosphere
    • /
    • v.16 no.3
    • /
    • pp.225-234
    • /
    • 2006
  • Convective systems propagate eastward with a persistent pattern in the longitude-time space. The characteristic structure and fluctuation of convective system is helpful in determining its predictability. In this study, convective index (CI) was defined as a difference between GOES-9 window and water vapor channel brightness temperatures following Mosher (2001). Then the temporal-spatial scales and variational characteristics of the summer convective systems in the East Asia were analyzed. It is found that the average moving speed of the convective system is about 14 m/s which is much faster than the low pressure system in the summer. Their average duration is about 12 hours and the average length of the cloud streak is about 750km. These characteristics are consistent with results from other studies. Although the convective systems are forced by the synoptic system and are mostly developed in the eastern edge of the Tibetan Plateau, they have a persistent pattern, i.e., appearance of the maximum intensity of convective systems, as they approach the Korean Peninsula. The consistency of the convective systems, i.e., the eastward propagation, suggests that there exists an intrinsic predictability.

The Trend of the Specialization of Hospitals in 2003 to 2005 in Metropolitan Cities (광역시소재 병원을 대상으로 한 전문화 수준의 다년간 추세분석)

  • Lee, Kwang-Soo;Chun, Ki-Hong
    • Health Policy and Management
    • /
    • v.20 no.3
    • /
    • pp.21-35
    • /
    • 2010
  • This study examined the changes in the service mix of Korean hospitals in 6 metropolitan cities between 2003 and 2005, and assessed whether the sample hospitals exhibit consistent trend or chance variation in multiple years. Three measures of hospital service mix, focusing on the specialization of services, were applied: information theory index, internal Herfindahl index, and number of distinct diagnosis-related groups (DRGs) treated. National Health Insurance claims were used to calculate the indexes. Specialization indexes were calculated in each year, and then examined to identify the pattern over time. Kappa analysis was applied to assess the agreements of specialization score between two years after hospitals were categorized into 4 groups with quartiles. Kappa score showed that the service mix of hospitals were changed during the study years. Specialization scores were increased given the market structure for three years. Hospitals which showed higher or lower specialization scores than the average of the scores consistently classified into the same group. Specialization indexes showed relatively consistent pattern over 3 years, and such consistencies were evident for hospitals regardless of the specialization status. Policy makers can identify the degree of specialization with the indexes, and it could provide a picture of how hospital services were mixed and changed over time.

A Pilot Study to Evaluate the Reliability of Pattern Identification Tool for Knee Osteoarthritis and to Analyze Correlation between Pattern Identification Tool and Knee Range of Motion, Visual Analog Scale and Western Ontario & Mcmaster Universities Osteoarthritis Index (퇴행성 무릎관절염 변증도구의 신뢰도 평가 및 무릎 ROM, VAS, WOMAC과의 상관관계에 대한 탐색적 연구)

  • Oh, Seung-Joon;Jang, Eunsu;Oh, Young-Seon;Kang, Wee-chang;Lee, Eun-Jung;Jung, In Chul
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.29 no.3
    • /
    • pp.113-128
    • /
    • 2019
  • Objectives To evaluate the pattern identification tool for knee osteoarthritis and to investigate the relationship between pattern identification tool and knee ROM (range of motion), VAS (visual analog scale) and WOMAC (Western Ontario & McMaster Universities osteoarthritis index). Methods We studied 50 patients who are diagnosed as degenerative osteoarthritis. With one patient dropping out, total of 49 patient went through pattern identification tool. Re-test of the pattern identification tool was implemented after about a week. The reliability was analyzed by calculating ICC (intraclass correlation coefficient). Also, reliability of each pattern identification score was calculated along with influence factor and correlation between knee ROM, VAS and WOMAC. Results Reliability of the pattern identification tool was evaluated as 'poor agreement beyond chance' with ICC value of 0.396. Reliablility of each pattern identification score was calculated and four out of five were measured 'good' with one 'moderate' reliability. Two of inter-item consistency were 'good', two were 'acceptable' and one was 'questionable'. Correlation between each pattern identification and knee ROM showed 'clear negative linear relationship' with two patterns. VAS showed 'clear positivie linear relationship' with all five patterns. WOMAC showed 'positivie linear relationship' with all five patterns. Conclusions According to the results, pattern identification tool for knee osteoarthritis seems to have meaningful relationship with other agnedas. Also, further research is needed to develop the tool.