• Title/Summary/Keyword: Pharmacognosy

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Protective Effect of Methanol Extract of Swietenia macrophylla Seeds on Oxidative States Associated with Streptozotocin Induced Diabetic Rats

  • Maiti, Anup;Dewanjee, Saikat;Kundu, Mintu;Mandal, Subhash C.
    • Natural Product Sciences
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    • v.13 no.4
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    • pp.295-299
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    • 2007

  • The methanol extract of seeds of Swietenia macrophylla King. (MESM) was studied for its antidiabetic activity in streptozotocin induced diabetic rats. It was principally aimed to correlate the efficacious role of MESM on reduction of oxidative state associated with diabetes. The extract was found to be potent antidiabetic evidenced by significant reduction of blood glucose level in diabetic rats (47.96% reduction of blood glucose level, at 300 mg/kg, on day 10). It was found that, MESM at 300 mg/kg, significantly decreased TBARS (35.03 and 22.22%) whilst increased GSH (86.75 and 31.45%), SOD (93.05 and 45.88%) and CAT (56.99 and 68.46%) levels in liver and kidney respectively in diabetic rats.

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Pharmacognostic Evaluation of Curcuma aeurigenosa Roxb.

  • Srivastava, Sharad;Nitin, Chitranshi;Srivastava, Sanjay;Dan, Mathew;Rawat, A.K.S.;Pushpangadan, Palpu
    • Natural Product Sciences
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    • v.12 no.3
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    • pp.162-165
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    • 2006

  • Curcuma aeruginosa Roxb. (FamilyZingeberaceae), commonly known as 'pink and blue giner' is widely used in Indian system of medicine since time immemorial. The plant is found well in wild habitat and cultivated in southern India. The plant is distinguished by red corolla lobes and ferruginous or greenish-blue rhizome. Rhizoma is used medicinally as anti-diarrheal, anti-fungal; external use as astringent for wounds. A detailed pharmacognostic evaluation of its rhizome showed total ash 6.1%, acid insoluble ash 1.20%, alcohol soluble extractives 3.70% , water soluble extractives 14.50%, sugar 20.93%, starch 41.85%, and tannins 0.68%. Oh hydro distillation, the rhizomes and sessile tubers yielded 0.17% oil.

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