• Herbal Formula Science
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• v.11 no.1
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• pp.1-18
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• 2003

Science of prescriptions is an important part in the education of Korean Oriental Medicine. In spite of that, there is less agreement on measures for improving the education quality of science of prescriptions. Science of prescriptions can be classified into generalities and particulars. This study sought to present contents that must be incorporated into Introduction to Science of Prescriptions to enhance the quality of education by examining both teaching materials being used in colleges of traditional Chinese medicine and those of Korean oriental medicine and the Introduction part of books related with science of prescriptions. And when this study was carried out, training Korean oriental medicine practitioners and researchers and educators of science of prescriptions was taken into account. It is judged that Introduction to Science of Prescriptions needs to be divided into seven chapters and that each chapter requires containing opinions of ancient doctors and references to lay the basis of learning and revised and practical contents in addition to traditional ones. Chapter One Introduction (Conception, History, Disciplinery, Study, How to Learn, Range of Study, How to Study, Academic Activities) Chapter Two Prescriptions and Selection of Treatment Based on the Differential Diagnosis Chapter Three Prescriptions and Therapeutic Methods (Eight Therapeutic Methods, Sixty Four Therapeutic Methods etc.) Chapter Four Classification of Prescriptions Chapter Five Designing and Modification of Prescriptions (Compatibility, Designing, Modification) Chapter Six Preparation Forms of the Prescriptions (Origin, Charicteristics) Chapter Seven Methods of Decocting and Taking Korean Oriental Herbal Medicines Appendix Tables of Apothecaries' Measures and Weights in Current and Ancient Times

• Herbal Formula Science
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• v.17 no.1
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• pp.1-16
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• 2009

This report describes the studies as follows through the research of Basic-prescriptions about 123 prescriptions in high-chepter(上統) from Bang-Yak-Hap-Pyun(方藥合編). There are 24 Basic-prescriptions including Sagunja-tang(四君子湯), Samul-tang(四物湯), Sogeonjung-tang(小建中湯), lijung-tang(理中湯), Dangguibohyul-tang(當歸補血湯), Yijin-tang(二陳湯), Gauwon-chun(擧元煎), Jeongweon-eum(貞元飮), and Yukmichiwhang-won(六味地黃元), etc. about 123 prescriptions in high-chepter(上統) from Bang-Yak-Hap-Pyun(方藥合編). There were many cases compounding the Basic-prescriptions each other. So I investigated those cases. The results were the other typed (blended) Basic-prescriptions including Palmul-tang(八物湯), Sipjeondaebo-tang(十全大補湯), Yukgunja-tang(六君子湯), Bojungyikkee-tang(補中益氣湯), SsangHwa-tang(雙和湯), and Gwibitang(歸脾湯). And I investigated about pathologies in connection with these Basic-prescriptions. Oriental Medical Pathology applied with these Basic-prescriptions were Giheo(氣虛), hyulheo(血虛), Gihyulguheo(氣血俱虛), Biheohan(脾虛寒), Giheo-dameum(氣虛痰飮), Giheohaham(氣虛下陷), Sineumheo(腎陰虛), etc. These results indicated that 123 prescriptions in high-chepter from Bang-Yak-Hap-Pyun are composed of Bojei(補劑) to treatment against many kinds of Infirmity and promote physiological function.

• Herbal Formula Science
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• v.9 no.1
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• pp.207-214
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• 2001

For the purpose of developing KOREA herbalogy and prescription therapeutics I study the prescriptions among the DONG-UE-BO-GAM. The conclusions are as fallows; 1. There were total 97 prescriptions contended the Bupleurum as gunyak among the DONG-UE-BO-GAM. 2. The currental prescriptions contended the Bupleurum as gunyak were HAN period :1 disease 1 prescription, SONG period :6 diseases 6 prescriptions, GUEM and WON period: 14 diseases 23 prescriptions, MYONG period: 30 diseases 63 prescriptions. 3. The most high frequency of currental effect of the Bupleurum were HAN period: sang-han(傷寒), GUEM and WON period: hak(?), sang-han(傷寒) and gol-gueng-yel(骨蒸熱), MYONG period: sang-han(傷寒), hak(?), on-yek(溫疫), juek-chui(積聚) and an(眼). 4. The most high frequency effect of the Bupleurum as gunyak were sang-han(傷寒): 15 prescriptions, hak(?): 12 prescriptions, on-yek(溫疫) 7 prescriptions etc.

• Journal of Korean Medical classics
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• v.21 no.1
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• pp.111-122
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• 2008

At the book I of "The Golden Mirror of Medicine[醫宗金鑑] The Elimination and Supplement about Famous Prescription Comments[刪補名醫方論]", 22 prescriptions are recorded. At the first part of the book, it mainly described about the prescriptions of invigorating Gi[補氣], which is followed by the prescriptions on enriching blood and nourishing vital essence fluid[補陰血], and the prescriptions on strengthening Gihyeol[補氣血] and tranquilization[安神] are described at the last part of the book. At the current review, the 8 prescriptions of strengthening Gihyeol[補氣血] and tranquilization[安神] of the last part of the book I will be translated, and compared with the similar related comments in the book of "The Famous Prescription Comments on Ancient and Modern Times[古今名醫方論]" to review about the characteristics of formula, prescriptions notes and the relationship of these contents. In terms of formula, the order of prescriptions to strengthen Gihyeol[補氣血] could be listed from the indirectly strengthening prescriptions to the directly strengthening prescriptions. In addition, the list of prescriptions will be sequenced by following the order of weak strengthening prescriptions to the strong strengthening prescriptions. The order of tranquilization prescription must be ordered for the symptoms showing mild psychological symptoms to severe symptoms in terms of severity of symptom, and will be ordered from the prescriptions highly dependent on invigorating Gi[補氣] to the prescriptionless dependent on invigorating Gi[補氣]. In the way of controlling Premier Fire[相火], these prescriptions are ordered from the prescriptions that use indirect methods to the prescriptions that use direct methods Characteristics of the prescription notes could be mentioned that the herbs of invigorating Gi(補氣) is pivotal in strengthening Gihyeol[補氣血] and the sour flavor and pungent flavor acted as negative and positive[陰陽的] when sour flavor and pungent flavor are used to enrich liver, and that sweet flavor could easily indigested to cause abdominal distension. When comparing with the content of "The Famous Prescription Comments on Ancient and Modern Times[古今名醫方論]", it mostly adopted the content as it is, but differentiation of the formula and addition of 2 new prescriptions with their explanation in the middle of the book could be considered to be creative aspect that helped the convenience of readers.

• The Journal of Korean Medical History
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• v.31 no.1
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• pp.105-122
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• 2018

Most of the prescriptions currently used by Korean medicine institutions to treat patients are delivered in the form of decoctions. The author reviewed the five-viscera section (五臟門) of Euibangyoochui (醫方類聚), which is composed of theory, medicinals, diet, taboo, acupuncture and moxibustion, and exercises. The medicinals cover a total of 1,144 prescriptions cited from 14 medical books, and provides a wide range of prescriptions and delivery options, including decoctions, powders and pills. Of the 1,144 prescriptions, the author notes that among them, 577 prescriptions which use powders (41%) are the most popular; 444 are pills (31%) and are the second most popular; 329 decoctions (23%) are the third most popular, and 64 other prescriptions are 5 percent. Expanding treatment options and delivery of medicinal prescriptions presented in the five-viscera section (五臟門) of Euibangyoochui (醫方類聚), is beneficial to both patients and doctors. The author suggests that expansion of herbal treatment options will provide opportunities to overcome current treatment limitations in the Korean medical service industry.

• Herbal Formula Science
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• v.23 no.2
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• pp.245-259
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• 2015

Objectives : This study is intended to establish the areas of use of the major effects of Coptidis Rhizoma-Evodiae Fructus Pair in the Prescriptions. Methods : Prescriptions that include both Coptidis Rhizoma and Evodiae Fructus have been selected with the use of programs offered by http://www.koreantk.com, http://youl.net/data . This study compared and analyzed the main effects of the selected prescriptions. Results : Prescriptions that work on upper digestive system tend to have Coptidis Rhizoma to Evodiae Fructus ratio of 2:1~10:1, and Prescriptions that work on lower digestive system tend to have ratio of 1:1. When Coptidis Rhizoma takes up 50% or more of the total dose of the prescriptions, these prescriptions tend to have major effect on the upper digestive system, and when it takes less than 50%, these tend to have major effect on the lower digestive system on the contrary. Conclusions : The prescriptions based on Coptidis Rhizoma-Evodiae Fructus Pair have a tendency to treat digestive problems caused by mass of fever in Liver-system. On this basis, further studies are expected to unveil the effectiveness of these prescriptions on adult diseases.

• Journal of Sasang Constitutional Medicine
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• v.35 no.4
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• pp.10-22
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• 2023

Objectives The aim of this study is to explore the mechanism of action and target diseases of Sasang constitutional prescriptions using a multiscale interactome approach. Methods The compound and target information of Sasang constitutional prescriptions were retrieved from various databases such as the TM-MC, STITCH, and TTD. Key targets for Sasang constitutional prescriptions were identified by selecting the top 100 targets based on the number of simple paths within the constructed network. Diffusion profiles for Sasang constitutional prescriptions and diseases were calculated based on a biased random walk algorithm. Potential diseases and key mechanisms of Sasang constitutional prescriptions were identified by analyzing diffusion profiles. Results We identified 144 Sasang constitutional prescriptions and their targets, finding 80 herbs with effective biological targets. A cluster analysis based on selecting up to 100 key targets for each prescription revealed a more cohesive grouping of prescriptions according to Sasang constitution. We then predicted potential diseases for 62 Sasang constitutional prescriptions using diffusion profiles calculated on a multiscale interactome. Finally, our analysis of diffusion profiles revealed key targets and biological functions of prescriptions in obesity and diabetes. Conclusions This study demonstrates the effectiveness of a multiscale interactome approach in elucidating the complex mechanisms and potential therapeutic applications of prescriptions in Sasang constitutional medicine.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.6
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• pp.1543-1547
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• 2004

In this study, symptoms, pathologies, compositions and clinical applications of 52 prescriptions for woman-related disease treatment descripted in Bang Yahk Hap Peun were investigated. The results were same as following; Classification of prescriptions for woman-related disease treatments was 23 prescriptions in high-chepter, prescriptions in 16 medium-chepter, and prescriptions in 13 low-chepter prescriptions and the frequency of clinical applications for high-chepter, medium-chepter and low-chepter prescriptions was 44%, 31% and 25%, respectively. Clinical applications of woman-related disease prescriptions were identified aocording to pre-pregnancy and post-birth, uterus, breast disease, before pregnancy. Infertile, emmeniopathy, uterus Blooding made practical application to high frequency in the treatments. Oriental Medical Pathology applied with prescriptions were Biheo(脾虛), Ganbinoyool(肝脾怒鬱), Infirmity(虛弱), 熱入血室, Jungpung(中風), Gihyulguheo(氣血俱虛), hyulheo(血虛), Aeohyul(瘀血) etc. Prescriptions applied with the most frequency in woman-related disease were Samuoltang(四物湯), Sagunjatang(四君子湯), Gungkuitang(芎歸湯), Boanbaekchuolsan(保安白朮散), Dangguibohyeltang(當歸補血湯), Sanhyointang(酸棗仁湯), Dohongsamuoltang(桃紅四物湯), Jipeisan(芷貝散), Silsosan(失笑散).

• Herbal Formula Science
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• v.10 no.1
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• pp.41-55
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• 2002

There are total 403 prescriptions containing Radix Scutellariae in Donguibogam and among them, 106 prescriptions treat Radix Scutellariae as a principal medicine. This report describes the study on therapeutic range, symptom, pathology and composition of 106 Radix Scutellariae-main blended Prescriptions from Donguibogam. The frequency and percentage of Radix Scutellariae-main blended prescriptions for the therapeutic range are as follows; cold symptom-complex is the most frequent(11 prescriptions, 10.37%) and gynecology is second(10 prescriptions, 9.43%). The symptoms that Radix Scutellariae-main blended prescriptions are made out for are 70 prescriptions of 28 therapeutic ranges, for example, minor Eum physical appearance, fire of triple burners jaundice, etc. The main pathologies that Radix Scutellariae-main blended prescriptions are being affected by cold, fire triple burners, dampness and heat, wind and heat, heat of heart and lung, heat of liver, heat of spleen, etc. Through the research into the composition of Radix Scutellariae-main blended prescriptions, the kind of medicines and certain rules of compounding medicines centering on Radix Scutellariae are deduced as follows: The main combinations of herbal medicines are Radix Scutellariae and Fructus Gardeniae, Radix Scutellariae and Rhizona Rhei, and Radix Scutellariae, Rhizona coptidis and Fructus Gardeniae. The main combinations of prescriptions are Yihwanghwan(Radix Scutellariae, Rhizoma Cotidis, Radix Glycyrrhizae), Boanbaekchulsan(Radix Scutellariae. Rhizoma Atractylodis macrocephalae), Sambohwan(Radix Scutellariae, Rhizoma Cotidis, Cortex Phellodendrj), Samhwangwon(Radix Scutellariae, Rhizoma Cotidis, Rhizoma Rhei), Hwangryeonhaedoktang(Radix Scutellariae, Cortex Phellodendri, Rhizoma Cotidis. Fructus Gardeniae), Daegumhwahwan(Radix Scutellariae, Rhizoma Cotidis, Cortex Phellodendri. Rhizoma Rhei). Sanyeolumja(Radix Scutellariae. Rhizoma Cotidis. Radix Osterici koreani. Radix Ledebouriellae), etc.

• Herbal Formula Science
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• v.23 no.1
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• pp.77-89
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• 2015

Objectives : This Study aims to extract the actual prescriptions used frequently in the clinical settings and the frequently used prescription list of textbook on herbal formulae by comparing the prescriptions recorded in the textbook on herbal formulae, and to examine the range of the efficacies of the corresponding prescription on the basis of the records of the Electronic Medical Record (EMR). Methods : By making comparison of the herb weight ratios of the prescriptions recorded in the textbook on herbal formulae with those recorded in EMR, the frequency is measured on the basis of the textbook on herbal formulae prescription and the frequency indication is computed for the clinical prescriptions with lower level of differences. Results & Conclusions : On the basis of the details of the clinical prescriptions used at the P Hospital, Yugmijihwang-tang, Samlyeongbaegchul-san, Jugyeobseoggo-tang, Maegmundong-tang, Olyeong-san and Baegho-tang, among the similar prescriptions for which the title prescriptions of the textbook on herbal formulae and the herbal composition coincide by more than 80%, are not included in the list of prescriptions covered under the national health insurance system even though they are frequently used prescriptions.