• Title, Summary, Keyword: Research and Developmen

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Silica Induces Nuclear Factor-kB Activation through TAK1 and NIK in Rat2 cell line

  • Young Lim;Nam, Hae-Yun;Rha, Suk-Joo;Kim, Young-Hoon;Cho, Yong-Yeun;Yang, Ki-Hwa;Kim, Kyoung-Ah;Lee, Kweon-Haeng
    • Proceedings of the Korean Society of Toxicology Conference
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    • pp.75-75
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    • 2003
  • Silica has been known to be a factor in acute cell injury and chronic pulmonary fibrosis. In Rat2 fibroblasts, silica induced the activation of NFkB, which plays a crucial role in regulating the expression of many genes involved in the subsequent inflammatory response. In addition, we observed that TAK1 and NIK were involved in silica-mediated NF-kB activation in Rat2 cells. (omitted)

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A Study on the influence of Productivity improvement of middle and small sized company's learning organization on productivity (중소기업 학습조직 활성화가 생산성에 미치는 영향에 관한 연구)

  • Jo, Yu-Jin;Kang, Kyung-Sik
    • Journal of the Korea Safety Management & Science
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    • v.19 no.4
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    • pp.283-290
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    • 2017
  • In knowledge information society entering global unlimited competition era, our middle and small sized companies are the base of national and enterprise competitiveness and core base of national economy as an origin of jobs. The competitiveness of middle and small sized companies is so important to decide the level of the competitiveness of the whole industries, but the gap from big sized company is much low in comparison with advanced countries from angles of important factors of enterprise growth, productivity and technological competitiveness, so, it's urgent to improve the competitiveness through productivity enhancement. The purpose of this research is to do a positive study on effects of learning organization management outcomes of middle and small sized company on enterprise productivity among various types of outcome brought for strengthening of enterprise competitiveness. It confirmed learning organization has functions and usefulness as a management tool bringing positive effects on enterprise productivity through the Productivity improvement.

The Developmen a Standarized Instrument and an Analysis of Lifestyle Patterns of Residents in Seoul (서울시 거주자의 생활양식 측정도구 개발 및 유형분석)

  • 윤복자
    • Journal of the Korean Home Economics Association
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    • v.32 no.2
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    • pp.255-263
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    • 1994
  • The objectives of this study were : 1) to find research trends on lifestyles 2) to analyze the lifestyle patterns of middle class residents in Seoul and 3) to develop a standarized instrument to measure lifestyles. Questionnaires were administered to 1615 homemakers in Seoul, The statistics with the SPSS software package was used for factor analysis. The major findings were as follows: the lifestyles of middle class residents in Seoul were categorized into six patterns : Fashion oriented Interior Design Oriented Economy Concerned Simplicity in Eating Hobby Oriented and Health Concerned. A standarized instrument using validity and reliability testes for lifestyles was developed.

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Developmen tof a Production lnformation System for Marine Propellers (박용프로펠러 생산정보시스템 개발)

  • Park Jaeseong;Kim Dong-Soo;Jun Cha-Soo;Park Jung W.;Ju Sang-yoon
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • pp.194-199
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    • 2003
  • Developed m this research is a production information system for marie propellers. The paper deals with surface modeling and tool path generation modules of the system. Since the input point data may have some errors, the data is examined using the 2nd divided difference. The point data is interpolated to a $G^2$ chord-length spline surface with some end-conditions. The effects of the various end-conditions on the interpolated surface are discussed in the paper. The tool paths for blade, fillet, and boss of the propeller are generated. Some illustrative examples from an industry are presented.

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Trends of Government Funded Research for Kampo Medicine in Japan and It's Implication (일본에서의 한방의학(漢方醫學)에 대한 국비 지원 연구 동향과 그 함의)

  • Jeung, Chang-Woon;Choi, Chang-Hyuk;Jo, Hee-Geun;Song, Min-Yeong;Baek, Eun-Hye
    • Journal of Korean Medicine Rehabilitation
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    • v.28 no.1
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    • pp.121-131
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    • 2018
  • Objectives We analyzed the trends of government-funded research on Kampo medicine in Japan to provide advanced evidence to R&D support policy for Korean medicine, and to introduce new research fields and trends to the researchers. Methods We reviewed the researches on Kampo medicine through 'research-er.jp' and 'KAKEN' database which contain R&D status in Japan and scientific research funding project issued by the Japan Ministry of Education, Culture, Sports, Science and Technology. Results Since 1976, government-funded research on Kampo medicine has been continuously announced, and now 533 tasks have been completed or are in progress. The average duration of the study is 2.54 years, but it has been prolonged to 3.52 years in recent years. 4~5 million yen was supported per project for laboratory research, and an average of 44,342 thousand yen was supported per project for specialized laboratory research and clinical research. Conclusions Despite the absence of systematically supporting departments, the researches on Kampo medicine in Japan were qualitatively superior since they focused on providing the scientific basis for clinical application. As competition in the world's traditional medicine market becomes more intense, it is necessary to improve the competitiveness of Korean medicine. Therefore, a keen interest in Korean medicine and active support from the government is needed.

A Cooperation Mechanism among Seller Agents based on Exchanging Goods in Agent-mediated Electronic Commerce

  • Ito, Takayuki;Hattori, Hiromitsy;Shintani, Toramatsu
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • pp.89-96
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    • 2001
  • Agent-mediated electronic markets have been a grow-ing area of agent research and developmen tin recent year. There exist a lot of e-commerce sites on the In-ternet(e.g. Priceline, com, Amazon, com etc). These e-commerce site have proposed new business models for effective and efficient commerce activity. Intelli-gent agents have been studied very widely in the field of artificial intelligence, For purpose of this paper, an agent can act autonomously and collaboratively in a network environment on behalf of its users. It is hard for people to effectively and efficiently monitor, buy, and sell at multiple e-commerce sites. If we intro-duce agent technologies into e-commerce systems, we can expect to further enhance the intelligence of their support. In this paper, we propose a new coopera-tion mechanism among seller agents based on exchang-ing their goods in our agent-mediated electronic market system. G-Commerce. On G-Commerce, seller agents and buyer agents negotiate with each other. In our model, seller agents cooperatively negotiate in order to effectively sell goods in stock. Buyer agents coopera-tively form coalitions in order to buy goods based an discount proices. Seller agent's negotiation goods. Our current experiments show that exchanging mechanism enables seller agents to effectively sell goods in stock. Also, we present the Pareto optimality of our exchang-ing mechanism.

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Embryonic Developmen Larvae and Juveniles of the Small Yellow Croaker (Larimichthys polyactis) Reared in Aquarium (실내수조에서 사육한 참조기 배발생 및 자치어의 형태)

  • MYOUNG Jung-Goo;KIM Young Uk;PARK Yong-Joo;KIM Pyeong-Ki;KIM Jong-Man;HUH Hyung Tak
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.37 no.6
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    • pp.478-484
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    • 2004
  • On 11 June 1991, eggs from the brood stock of small yellow croaker (Larimichthys polyactis) were artificially fertilized using the standard dry method and were hatched. Each of the fertilized eggs (1.1-1.2 mm in diameter) had an oil globule and was transparent and buoyant. The fertilized eggs hatched in a range of water temperatures $(17.5-20.3^{\circ}C)$ 44 hrs after fertilization. The total lengths of the newly hatched larvae were 3.1-3.3 mm, and these hatchlings had 31 myotomes (10+21). Melanophores and yellow-brown chromatophores were concentrated on the head, at the ventral part of the yolk, and in the middle of the tail. Four days after hatching, the larvae completely absorbed the yolk and became flexions of 5.1-5.5 mm in total length. Fifteen days after hatching, one spine (the anterior tip of the maxillary) appeared in the upper jaw and three spines developed at the upper parts of the eyes and on the posterior part of the head. At this stage, the larvae were approximately 8.3 mm long. Thirty-nine days after hatching, juveniles (1.9-3.4 mm in total length) had a pointed tail fin. By 66 days after hatching, the juvenile fish (about 4.0-6.5 mm in total length) were similar to adult fish in body shape. The larvae of L. polyactis could be distinguished from those of L. croacea by two distinct characteristics: the large number of vertebrae (28-29), and a relatively small bony ridge on the occipital region of the head.

A Study on the Development of Food Truck Concept based on Demographic Characteristics (인구통계적 특성에 기초한 푸드트럭 컨셉개발에 관한 연구)

  • Kim, Heon Choul
    • Culinary science and hospitality research
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    • v.23 no.7
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    • pp.149-158
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    • 2017
  • This study aimed to develop food truck concept based on demographic characteristics by using conjoint analysis. This study investigated the attributes importance and attributes level based on gender, age and income. Results of the research were following. First, as a result of analyzing the attributes importance and attributes level of gender, age, and income, it found that the price was more important than the type of food. The shape of food, a design of the truck and service are the following features of the attributes importance. Second, in the entire of market analysis, packaging was the most important factor next to the price and the food shape. Third, according to gender analysis, male and female prefer Korean style with price range of 5,000~7,000 won. Men prefer take - out menu such as plastic packaging and traditional truck design. Also, the study showed that women prefer having a meal at restaurant, paper packaging style and modern design. Fourth, according to the age analysis results, all of ages group prefer the price range of 5,000~7,000 won except for people who are 60s and beyond. Also, in the food type, people prefer Western style in their 20s, Japanese style in their 30s and Korean style in their 40s, 50s, 60s. Fifth, according to income analysis, Western menus with income of 4,000,000~5,000,000won are preferred a price range of 7,000~10,000won and Japanese menus with income more than 5,000,000won are preferred a price range of 7,000~10,000won.

A Study on the Change of the Corrosion Products by the Activity of Iron Reducing Bacteria for Corrosion Carbon Steel (부식철편에 있어서 철환원능력을 갖춘 세균의 활동에 의한 부식생성물의 변화)

  • Lee, So-Yeon;Matsui, Toshiya;Yoshikawa, Hideki
    • Journal of Conservation Science
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    • v.26 no.4
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    • pp.407-416
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    • 2010
  • Bacteria with ability for iron reduction in the soil can use corrosion products of iron remains as energy source. The activities of this bacteria cause the change of corrosion products. As a result, it can be difficult to identify corrosion products promoting corrosion of iron remains. The purpose of this study, is to investigate the change in corrosion products that bacteria causes and to improve understanding about the corrosion of iron remains. To simulate corroded condition of excavated iron remains, carbon steel corroded by solution of NaCl and $Na_2SO_4$ was prepared. Then the prepared carbon steel was immersed in a liquid medium with bacteria. The incubation period was 42days. After experiment, the carbon steel was analyzed by SEM-EDS, X-ray diffraction method. The result is that the carbon was changed to green because of activity of bacteria and that the plate crystal and lozenge crystal were generated on the corrosion specimen. Also, we confirmed that the activities of bacteria differenciated colors and forms of corrosion products.