• Journal of the Korean Society of Food Science and Nutrition
• /
• v.28 no.2
• /
• pp.471-476
• /
• 1999

The effects of total dietary restriction(100% restriction of energy intake) on thiobarbituric acid reactive substance(TBARS) contents and intracellular antioxidant enzymes activities in the liver and kidney of young male Sprague Dawley rats were studied. The TBARS contents were reduced in both liver and kidney, up to 77% and 79% of the control rats, fed ad libitum, respectively at 7 days after dietary restriction . Superoxide dismutase(SOD) activities in the liver and kidney of rats were increased significantly by total dietary restriction. However, the activity of catalase in kidney was decreased 27% at 6 days after dietary restriction, but this enzyme activity did not change in liver. The changes of glutathione peroxidae(GSHPx) and catalase activities in the liver and kidney of rats with dietary restriction were not significant. These result suggested that dietary restriction reduce the free radical induced by tissue damage, as determined by TBARS content, in both the liver and kidney but the changes of activities of antioxidant enzymes may not be a contributory factor in reducing oxidative damage to tissue.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.8
• /
• pp.485-493
• /
• 2019

The purpose of this study is to gain basic information to manage the free choice activities of kindergarten by investigating the teachers' perception of restriction rules. The subjects of the study were 200 kindergarten teachers who worked in J province. The instrument used for this study was a questionnaire that focused on teachers' perception about the restriction rules for the free choice activities. The results of this study were as follows. First, the teachers considered restriction rules in the art center as the most important factor. Second, the teachers recognized that limiting the number of players in a same center is the most important thing among the three restriction rules. Third, the teachers' perception regarding the necessity of restriction rules is as follows. The rule of restricting the number of players is needed to prevent too many players focusing in a certain center. The rule of restricting play time is necessary to encourage children to play in various centers, and the rule of restricting play space is crucial to solidify the educational purpose that every interest center has. The meaning and the necessity of the restriction rules on children's free choice activities were further discussed as connected with children's right to play.

• The Korean Journal of Food And Nutrition
• /
• v.11 no.4
• /
• pp.460-465
• /
• 1998

The effects of food restriction on the fecal microflora, moisture, pH, indole, ${\beta}$-glucosidas, and ${\beta}$-glucuronidase in rate were studied for 4 weeks. Four groups of rats for feeding was allocated to the following experimental trials : (1) control containing 1% cellulose, (2) control with food restriction, (3) treatment of diet containing butterbur, (4) treatment of butterbur combined with diet restriction. Treatment of butterbur combined food restriction significantly (p<0.05) reduced the growth of Bacteroides, Peptococus, Streptococcus, Staphylococcus, and Escherchia coli, respectively. No remarkable changes in the ${\beta}$-glucosidase and ${\beta}$-glucuronidase activities were observed but indole content significanlty decreased. Based on these results, treatment of butterbur combined with diet restriction in rats had a significantly effect for preventing the growth of those pathogenic microorganims.

• Korean Journal of Childcare and Education
• /
• v.12 no.1
• /
• pp.57-81
• /
• 2016

The purpose of this study was to find out the feature of children's play according to a player number restriction rule in the free choice activities. And it is expected that the result of this study will contribute to improving the management of free choice activities. The participants of this study were a homeroom teacher, professor as a co-researcher and 25 4-year-old children of a private kindergarten. The data were collected by observation, children interview and reflective journal of the teacher from July to October in 2014. The results indicated that the children were stressed out with using name cards for presenting center selection, showed overcompetitive behaviors, and frequently violated the rules. The researchers found that the restriction rule had some dysfunctions, which were interferences of moral development, social-emotional development, self-regulation development, preventing safety-accident and free choice behavior. The researcher as a teacher abandoned the player number restriction rule, and observed the children's play. As a result, children's self-regulation abilities on physical space, play and conflicts improved and the teacher changed her strategy when managing free choice activities. Based on the results, the needs of various restriction rules and appropriate methods for applying the rules in free choice activities were further discussed.

• Journal of Convergence for Information Technology
• /
• v.11 no.3
• /
• pp.87-94
• /
• 2021

This study was conducted to identify the mental health and quality of life of cardiovascular disease patients by their activities restriction through the second analysis of the 7th KNHANES collected from 2016 to 2018. The subjects of this study were 521 adults with angina or myocardial infarction who had no missing variables among 24,269 subjects. The difference between mental health and quality of life according to the activity restriction was analyzed by Chi-square method and the effect of mental health and quality of life by activity restriction by Logistic regression method using the SAS 9.4 version. The results of the analysis showed that the stress level, the depression for the last two weeks and suicide thought level was high when there was activity restriction, which had a significant effect on mental health. Mobility, selfcare and usual activities were disrupted, and pain/inconvenience and anxiety/depression increased when there was activity restriction, which also showed a significant effect on quality of life. Therefore, it is suggested that the development and operation of effective physical activity promotion program to minimize activity restriction is necessary to improve mental health and quality of life of cardiovascular patients.

• KSBB Journal
• /
• v.9 no.1
• /
• pp.63-71
• /
• 1994

During the last decade enzyme reaction in organic solvent has been studied to show that specificity in buffer is different from that in organic solvent. The specificity of restriction enzyme was effected by various factors such as ionic strength, salt organic solvent and temperature. In this study, restriction enzyme PvuII which is used most frequently in genetic engineering and the substrate was vector pGEM3 whose sequence was already known were used. As a result the recognition sequence site was changed in the presence of organic solvents whose Log P are -1.5∼0. Their specificities were contrast with activities were contrasted. Specificities were not changed in organic solvent easily in inactivating enzyme. We think that the enzyme recognition site was not changed randomly but by preferential order. A recombinant vector which does not contain typical cleavage site CAG↓CTG was cleaved in 20% ethanol solution. This result might show that restriction enzyme could be used to cleave at unusual sites by changing the reaction conditions.

• Korean Journal of Social Welfare Studies
• /
• v.42 no.2
• /
• pp.323-350
• /
• 2011

Work ability is a fundamental factor to determine who are the recipients of disability benefits or employment services. Disability Grade based on medical impairments is used as a work ability assessment in Korea, but it has been heavily criticized that it does not assess disabled person's work ability adequately. This study tried to find out an index which explains employment status of disabled persons the best among four work ability assessment indexes of disability grade, level of ICF activity limitations and participation restriction, level of help needed with daily activities, and self-assessed health status. As a result, the level of ICF activity limitations and participation restriction explained the employment status the best, and help needed for daily activities is the second, disability grade is the third, and self-assessed health status is the last. In conclusion, level of ICF activity limitations and participation restriction is the best work ability assessment in Disabled People Pension and Employment Policy for Disabled People. Therefore, it is the basic premise to develop a new work ability assessment index which consists of items in ICF activity limitations and participation restriction.

• Nutritional Sciences
• /
• v.8 no.4
• /
• pp.231-236
• /
• 2005

This study investigated the changes in the neuronal nitric oxide synthase (nNOS) and nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) activities during food restriction in the rat brain such as cerebral cortex, cerebellum, caudate pautamen and hypothalamus. The rats were placed on a restricted feeding schedule consisting of half the ad libitum quantity for 3 days and 1, 2, 4, 6 and 9 weeks, and a free feeding schedule for 4 weeks. The loss of body weight peaked after 1 week of food restriction and persisted during the entire 9-week period of food restriction. The dramatic weight change in the first week ($12\%$) and the reduction in weight changes thereafter suggest that major adaptation changes occur early and body maintenance occurs subsequently. In the hypothalamus, the optical densities of the NADPH-d and nNOS immunoreactivities were found to be significantly higher in the 1-week and lower in the 9-week food restricted group than in the ad libitum fed control rats. In contrast, in the cerebral cortex, the optical densities of the NADPH-d- and nNOS-positive neurons were not changed significantly during the period of food restriction. This study provides the morphological evidence showing that food restriction has a significant effect on the nitric oxide synthesizing system of the hypothalamus.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.2
• /
• pp.803-809
• /
• 2015

Background: Colorectal cancer (CRC) is a leading cause of cancer-related death. Oxidative DNA damage may contribute to cancer risk and the antioxidant paraoxonase is one endogenous free radical scavenger in the human body which could therefore exert an influeence. Purpose: Aim of this study was to determine the role of serum arylesterase (ARE) and paraoxonase 1(PON1) activities in CRC patients and to find any association between (PON1) Q192R and L55M gene polymorphisms in CRC patients. Also the serum ARE and PON1 activities in CRC patients will be investigated before and after surgery Materials and Methods: This study involved a total of 50 patients with newly diagnosed CRC and 80 healthy controls. PON1 and ARE activities were determined using an enzymatic spectrophotometric method. PON1 Q192R and L55M gene polymorphisms were determined using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) based restriction fragment analysis. The restriction enzyme AlwI was used to examine the Q192R polymorphism and Hsp92II for the L55M polymorphism. Results: Significant differences in the PON1 Q192R polymorphism were found between patients and controls. The Q allele was more frequent in the patient group than in controls, while the R allele was more frequent in the controls. Significant differences were found in the L55M polymorphism. Additionally, there were significant differences in L and M allele frequencies (p=0.001). The serum activities of PON1 and ARE were low in QQ and MM genotype. Conclusions: serum PON1 and ARE activities were significantly lower in CRC patients compared to healthy subjects. The R allele may protect against colorectal cancer.

• Journal of the East Asian Society of Dietary Life
• /
• v.24 no.3
• /
• pp.291-300
• /
• 2014

This study determined the effects of television (TV) advertising restriction of Energy-Dense and Nutrient-Poor Foods on product and promotion activities by food companies producing or selling children's favorite foods. A survey using a selfadministered questionnaire was conducted via on-line or fax by marketers or R&D managers from 108 food companies. The data from 55 respondents (50.9%) were analyzed. Restriction exerted positive effects on food products with respect to compliance with labeling requirements (4.0 out of 5 points) and reinforcement of nutritional contents examination of new products (3.7 out of 5 points). Reformulations of products such as reduction of nutrients like sodium, sugar and fat were also reported. In addition, food companies underwent diverse changes in promotional activities, including modification of package designs and displays in stores, offering free gifts, discounts, etc. In conclusion, restriction of TV food advertising may contribute to improvement of children's food environment by encouraging food companies to make favorable product changes. On the other hand, the results also revealed that food companies adopt diverse marketing channels that are not yet under regulation. Hence, to make policies more effective, regulation needs to be extended from TV to other marketing channels to which children are easily exposed.