• Earthquakes and Structures
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• v.15 no.2
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• pp.123-132
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• 2018

In this paper the strain energy density (SED) model is used to analyze the seismic behavior of suspen-domes and a new criterion is established for judging the seismic failure based on a characteristic point in the SED model. Firstly, a nonlinear time-history response analysis was carried out using the finite-element package ANSYS for typical suspen-domes subjected to different ground motions. The seismic responses including nodal displacements, ratios of yielding members, strain energy density and structural maximum deformation energy were extracted corresponding to the increasing peak ground acceleration (A). Secondly, the SED sum ($I_d$) was calculated which revealed that the $I_d-A$ curve exhibited a relatively large change (called a characteristic point) at a certain value of A with a very small load increment after the structures entered the elastic-plastic state. Thirdly, a SED criterion is proposed to judge the seismic failure load based on the characteristic point. Subsequently, the case study verifies the characteristic point and the proposed SED criterion. Finally, this paper describes the unity and application of the SED criterion. The SED method may open a new way for structural appraisal and the SED criterion might give a unified criterion for predicting the failure loads of various structures subjected to dynamic loads.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.27 no.6
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• pp.1361-1372
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• 2017

If an external attacker takes from a victim's smartphone a copy of a secret application or an application to which fingerprinting technique is applied, secret information can be leaked or the legitimate user can be misunderstood as an illegal redistributor, which results in a serious security problem. To solve this problem, this paper proposes an Android application code protection scheme using fingerprint authentication and dynamic loading. The proposed scheme divides one application into CLR(Class LoadeR) and SED(SEperated Dex). CLR is an APK file with the ability to dynamically load the SED, and the SED is a file containing the classes required to run the application. The SED is stored inside the smartphone after being encrypted, and the SED can be decrypted only if the user is successfully authenticated using his or her fingerprint. The proposed scheme can protect the application code from the attacker who physically acquired user's smartphone.

• Molecules and Cells
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• v.40 no.9
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• pp.643-654
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• 2017

Autophagy is a degradation pathway in eukaryotic cells in which aging proteins and organelles are sequestered into double-membrane vesicles, termed autophagosomes, which fuse with vacuoles to hydrolyze cargo. The key step in autophagy is the formation of autophagosomes, which requires different kinds of vesicles, including COPII vesicles and Atg9-containing vesicles, to transport lipid double-membranes to the phagophore assembly site (PAS). In yeast, the cis-Golgi localized t-SNARE protein Sed5 plays a role in endoplasmic reticulum (ER)-Golgi and intra-Golgi vesicular transport. We report that during autophagy, sed5-1 mutant cells could not properly transport Atg8 to the PAS, resulting in multiple Atg8 dots being dispersed into the cytoplasm. Some dots were trapped in the Golgi apparatus. Sed5 regulates the anterograde trafficking of Atg9-containing vesicles to the PAS by participating in the localization of Atg23 and Atg27 to the Golgi apparatus. Furthermore, we found that overexpression of SFT1 or SFT2 (suppressor of sed5 ts) rescued the autophagy defects in sed5-1 mutant cells. Our data suggest that Sed5 plays a novel role in autophagy, by regulating the formation of Atg9-containing vesicles in the Golgi apparatus, and the genetic interaction between Sft1/2 and Sed5 is essential for autophagy.

• Infection and chemotherapy
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• v.50 no.4
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• pp.319-327
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• 2018

Background: Lancet-related needlestick injuries (NSIs) occur steadily in clinical practices. Safety-engineered devices (SEDs) can systematically reduce NSIs. However, the use of SEDs is not active and no study to guide the implementation of SEDs was known in South Korea. The lancet-related NSIs may be eliminated to zero incidence using a SED lancet with effective sharp injury protection and reuse prevention features. Materials and Methods: We implemented a SED lancet by replacing a conventional prick lancet in a tertiary hospital in a sequential approach. A spot test of the new SED was conducted for 1 month to check the acceptability in practice and a questionnaire survey was obtained from the healthcare workers (HCWs). A pilot implementation of the SED lancet in 2 wards was made for 1 year. Based on these preliminary interventions, a hospital-wide full implementation of the SED lancet was launched. The incidence of NSIs and cost expenditure before and after the intervention were compared. Results: There were 29 cases of conventional prick lancet-related NSIs for 3 years before the full implementation of SED lancet. The proportion of prick lancet-related NSIs among yearly all kinds of NSIs during two years before the pilot study was average 11.7% (22/188). Pre-interventional baseline incidence of all kinds of NSIs was 7.01 per 100 HCW-years. After the full implementation of SED lancet, the lancet-related NSIs became zero in the 2nd year (P = 0.001). The average direct cost of 18,393 US dollars (USD) per year from device and post-exposure medical care before the intervention rose to 20,701 USD in the 2nd year of the intervention. The incremental cost-effectiveness ratio was 210 USD per injury avoided. Conclusion: The implementation of a SED lancet could eliminate the lancet-related NSIs to zero incidence. The cost increase incurred by the use of SED lancet was tolerable.

• Korean Journal of Exercise Nutrition
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• v.24 no.3
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• pp.1-6
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• 2020

[Purpose] While the anti-obesity effects of exercise and capsiate are well-observed individually, the effect of exercise with capsiate intake has not been systematically explored yet. Therefore, the purpose of this study is to investigate whether the anti-obesity effects of exercise training can be further enhanced by capsiate intake. [Methods] 8-week-old male mice were divided into 3 groups (n = 8 per group): sedentary group (SED; nontrained), exercise-trained group (EXE) and exercise-trained group with 10 mg/kg of capsiate intake (EXE+CAP). All mice were offered high-fat diet and water ad libitum. The mild-intensity treadmill training was conducted 5 times a week for 8 weeks. After 8 weeks, metabolism during exercise and abdominal fat weight were measured. [Results] Body weight and the rate of total abdominal fat were significantly less in EXE+CAP than in SED but not between EXE and SED. The average of respiratory exchange rate during exercise was significantly much lower in EXE+SED (p = 0.003) compared to the difference between EXE and SED (p = 0.025). Likewise, the fat oxidation during exercise was significantly much higher in EXE+SED (p = 0.016) compared to the difference between EXE and SED (p = 0.045). Then, the carbohydrate oxidation during exercise was significantly much lower in EXE+SED (p = 0.003) compared to the difference between EXE and SED (p = 0.028). [Conclusion] In conclusion, the anti-obesity functions of exercise training can be further enhanced by capsiate intake by increasing fat oxidation during exercise. Therefore, we suggest that capsiate could be a candidate supplement which can additively ameliorate obesity when combined with exercise.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.1770-1774
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• 2010

하구는 담수와 해수가 만나 넓은 갯벌과 기수역을 형성하여 각종 생물의 서식지이자 어류의 산란지로 이용되는 생태학적으로 중요한 지역이다. 특히 한강 하구는 국내 4 대강 가운데 유일하게 하구둑이 설치되어 있지 않아 조수의 출입이 자유롭고 민간인 접근이 통제되어 있어 자연적인 하천지형과 기수역 생태계가 비교적 잘 보전된 구역이다. 본 연구의 모의영역은 한강 하류부로 상류 경계단은 행주대교, 하류 경계단은 전류단 수위표가 위치한 경기도 연천군 전곡읍 전곡 사랑교 부근으로 설정하였다. 지형자료는 한국건설기술연구원에서 2009년 8월 홍수사상 전 후에 대해 측량한 자료를 사용하였다. 한강 하구역에 대한 지형 격자를 구성하기 위하여 RAMS 전후 처리기인 RAMS-GUI를 사용하였으며, 구성된 지형 격자의 절점 수는 2,354개, 요소 수는 2,145개로 삼각요소와 사각요소가 혼용되어 있다. 구성된 격자망을 이용하여 2차원 하상변동 해석 모형인 SED-2D 모의를 통해 홍수사상에 의한 한강 하구부의 하상변동을 살펴보았다. SED-2D 모형은 미국 육군 공변단의 WES와 미 연방 도로국이 연계하여 개발되어 현재 국내외 2차원 하천해석에서 가장 널리 사용되고 있는 모형 중 하나이다. 하상변동 해석모형인 SED-2D를 통해 모의된 하상 변동량을 실제 측량된 홍수 전 후의 지형자료와 비교함으로써 모형의 성능을 분석하였다. 분석결과 SED-2D 모형의 경우 침식에 의한 하상변동이 모의되지 않았지만, 전반적인 하상변동 경향을 살펴볼 수 있음을 알 수 있었다.

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.5
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• pp.461-469
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• 2021

Background: The global population is aging rapidly, and accordingly, the number of patients with dementia is increasing every year. Although the need for dental treatment increases for various reasons in patients with dementia, they cannot cooperate during dental treatment. Therefore, behavioral management, including sedation (SED) or general anesthesia (GA), is required for patients with dementia. Thus, this study aimed to investigate the trends and effects of SED or GA in patients with dementia undergoing dental treatment in South Korea based on the Korean National Health Insurance claims data. Methods: This study utilized customized health information data provided by the Health Insurance Review and Assessment Service. Among patients with records of using sedative drugs during dental treatment from January 2007 to September 2019, patients with the International Classification of Diseases-10 code for dementia (F00, F01, F02, F03, and G30) were selected. We then analyzed the full insurance claims data for dental care. Age, sex, sedative use, and dental treatment of patients were analyzed yearly. In addition, the number of cases of GA or SED per year was analyzed, and changes in behavioral management methods with increasing age were investigated. Results: Between January 2007 and September 2019, a total of 4,383 (male, 1,454; female, 2,929) patients with dementia received dental treatment under SED or GA. The total number of SED and GA cases were 1,515 (male, 528 ; female, 987 ) and 3,396 (male, 1,119 ; female, 2,277) cases, respectively. The total number of cases of dental treatment for 4,383 patients with dementia was 153,051 cases, of which 2.22% were under GA and 0.98% were under SED. Midazolam was the most commonly used drug for SED. Conclusion: Although gingivitis and pulpitis were the most common reasons for patients with dementia to visit the dentist, GA or SED for patients with dementia was frequently used in oral and maxillofacial or periodontal surgery.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.54.3-55
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• 2016

We model the spectral energy distribution (SED) of the Class 0 protostar L1527 IRS using a dust continuum radiative transfer code RADMC-3D to study the initial condition of gravitational collapse. To constrain the envelope structure, we use the data obtained by Herschel /PACS, which covers the far-infrared regime ($55-190{\mu}m$) where the SED of L1527 IRS peaks. According to our modeling, a more flattened density profile fits the far-infrared SED of L1527 IRS better than the density profile of a rotating and infalling envelope. Thus, we employ the density structure of a Bonnor-Ebert sphere, which consists of the inner flat-topped and the outer power-law regions and is often used for describing the density structure of the youngest sources in the low mass star formation process. A Bonnor-Ebert sphere fits very well the observed SED at ${\lambda}$ > $10{\mu}m$, suggesting that L1527 IRS might collapse from an unstable Bonnor-Ebert sphere rather than a singular isothermal sphere.

• Journal of Environmental Science International
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• v.12 no.10
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• pp.1109-1116
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• 2003

The genetic algorithm is investigated fer parameters estimation of SED (storage - effective drainage) model from the Wi-stream watershed in Nakdong river basin. In the practical application of model, as a number of watershed parameters do not measure directly, it is desirable to make a good estimation from the known rainfall and runoff data. For the estimation of parameters of the SED model using the genetic algorithm, parameters of Green-Ampt equation(SM, K$\_$s/) for the estimation of an effective rainfall and initial storage(y$\_$in/) used in SED model are obtained a regression equation with 5, 10, 20 days antecedent precipitation. And as a consequence of computation, the parameters were obtained to satisfy the proposed objective function. From the comparison of observed and computed hydrographs, it shows a good agreement in the shape and the rising limb, peak, falling limb of hydrograph, so the SED model using the genetic algorithm shows a suitable model for runoff analysis in river basin.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.51.2-52
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• 2021

Pulsar Wind Nebula(PWN)는 radio부터 TeV band까지 넓은 파장에 걸쳐 복사를 하며 이 복사는 Spectral Energy Distribution(SED)으로 측정된다. 관측된 SED는 두 개의 주요한 bump를 보이는데 low-energy emission bump는 synchrotron radiation에 의해 만들어지고 high-energy emission bump는 inverse Compton scattering에 의해 만들어진다. 대부분 PWN들의 SED는 단일 전자 분포로 설명이 가능하지만 최근 연구 결과에 의하면 Crab nebula, G21.5-0.9 같은 일부 young pulsar wind nebula의 X-ray SED에서 단차나 기울기의 변화 등 단일 전자 분포로 설명하기 어려운 부분이 관측되기도 한다. 이런 PWN에 대하여 우리는 이중 전자 분포를 이용해서 broadband SED가 잘 설명이 되는지 확인하고 이를 통하여 PWN 입자 가속의 특성을 이해해보고자 한다.